carbamazepine has been researched along with Spasms, Infantile in 22 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Spasms, Infantile: An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In our patient, seizures immediately stopped upon initiation of vigabatrin treatment, and his development and neurological examination at one year are normal." | 7.78 | Ohtahara syndrome or early-onset West syndrome? A case with overlapping features and favorable response to vigabatrin. ( Fluss, J; Korff, CM; Picard, F; Vulliemoz, S, 2012) |
| "The drug encorat, an analogue of valproic acid (Sun, India) was given to 16 children aged from 4 month to 5 years suffering from resistant forms of early infantile epilepsy." | 5.07 | [The enkorat treatment of infantile spasms and the Lennox-Gastaut syndrome]. ( Badalian, LO; Iskander, MB; Kharlamov, DA; Medvedev, MI; Mukhin, KIu; Temin, PA; Veselov, NK, 1994) |
| " The point estimates of carbamazepine and lamotrigine efficacy showed their superiority with respect to all comparator antiepileptic drugs for the treatment of newly diagnosed focal epilepsy." | 4.98 | Comparative efficacy of antiepileptic drugs in children and adolescents: A network meta-analysis. ( Crescioli, G; De Masi, S; Guerrini, R; Ilvento, L; Lucenteforte, E; McGreevy, KS; Mugelli, A; Pugi, A; Rosati, A; Virgili, G, 2018) |
| "We report two female infants with early myoclonic encephalopathy (EME) whose intractable focal seizures were suppressed with lidocaine and carbamazepine (CBZ)." | 3.79 | Successful treatment of early myoclonic encephalopathy using lidocaine and carbamazepine. ( Kobayashi, K; Kodani, N; Maniwa, S; Nakano, K; Ohtsuka, Y, 2013) |
| "In our patient, seizures immediately stopped upon initiation of vigabatrin treatment, and his development and neurological examination at one year are normal." | 3.78 | Ohtahara syndrome or early-onset West syndrome? A case with overlapping features and favorable response to vigabatrin. ( Fluss, J; Korff, CM; Picard, F; Vulliemoz, S, 2012) |
| "In seven patients (58%) seizures and hypsarrhythmia stopped during the week after introduction of STM (10 mg x kg (-1)body weight day (-1))." | 2.70 | Add-on treatment with pyridoxine and sulthiame in 12 infants with West syndrome: an open clinical study. ( Debus, OM; Fiedler, B; Franssen, M; Köhring, J; Kurlemann, G, 2002) |
| "Interictal EEG showed hypsarrhythmia in 27 infants and multifocal spikes with normal or nearly normal background in 17 infants." | 2.70 | Infantile spasms: diagnosis and assessment of treatment response by video-EEG. ( Gaily, E; Granström, ML; Liukkonen, E; Paetau, R; Rekola, R, 2001) |
| "Epileptic spasms without hypsarrhythmia have been described in some series of patients, occurring either in infancy or childhood." | 1.42 | Epileptic spasms without hypsarrhythmia in infancy and childhood: tonic spasms as a seizure type. ( Carvalho, KC; Corso, JT; Ferrari-Marinho, T; Guaranha, MS; Marchi, LR; Naves, PV; Ramirez, MD; Seraphim, EA; Yacubian, EM, 2015) |
| "Oxcarbazepine has been reported to precipitate myoclonic, generalised tonic-clonic, absence, and complex partial seizures, and carbamazepine to precipitate absences, myoclonic seizures and spasms." | 1.38 | Possible induction of West syndrome by oxcarbazepine therapy in a patient with complex partial seizures. ( Mikati, MA; Singh, P; Veerapandiyan, A, 2012) |
| "Carbamazepine is a standard anticonvulsant in children and adults." | 1.31 | Carbamazepine in phenobarbital-nonresponders: experience with ten preterm infants. ( Bartmann, P; Elger, CE; Hoppen, T, 2001) |
| " The dosage was increased when she developed generalized tonic-clonic seizures and she is currently maintained on a maximal dose of a controlled release formulation." | 1.29 | Case summary: Kate. ( Ebbing, A; Kirkham, FJ, 1994) |
| " Dosage of both drugs was within the usual range." | 1.27 | Carbamazepine and benzodiazepines in combination--a possibility to improve the efficacy of treatment of patients with 'intractable' infantile spasms? ( Groh, C; Lischka, A; Müller, R; Tatzer, E, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 7 (31.82) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 8 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buttle, SG | 1 |
| Sell, E | 1 |
| Dyment, D | 1 |
| Bulusu, S | 1 |
| Pohl, D | 1 |
| Rosati, A | 1 |
| Ilvento, L | 1 |
| Lucenteforte, E | 1 |
| Pugi, A | 1 |
| Crescioli, G | 1 |
| McGreevy, KS | 1 |
| Virgili, G | 1 |
| Mugelli, A | 1 |
| De Masi, S | 1 |
| Guerrini, R | 1 |
| Sharawat, IK | 1 |
| Kasinathan, A | 1 |
| Sahu, JK | 1 |
| Sankhyan, N | 1 |
| Nakano, K | 1 |
| Kobayashi, K | 1 |
| Maniwa, S | 1 |
| Kodani, N | 1 |
| Ohtsuka, Y | 1 |
| Marchi, LR | 1 |
| Seraphim, EA | 1 |
| Corso, JT | 1 |
| Naves, PV | 1 |
| Carvalho, KC | 1 |
| Ramirez, MD | 1 |
| Ferrari-Marinho, T | 1 |
| Guaranha, MS | 1 |
| Yacubian, EM | 1 |
| Dilena, R | 1 |
| Striano, P | 1 |
| Gennaro, E | 1 |
| Bassi, L | 1 |
| Olivotto, S | 1 |
| Tadini, L | 1 |
| Mosca, F | 1 |
| Barbieri, S | 1 |
| Zara, F | 1 |
| Fumagalli, M | 1 |
| Veerapandiyan, A | 1 |
| Singh, P | 1 |
| Mikati, MA | 1 |
| Korff, CM | 1 |
| Vulliemoz, S | 1 |
| Picard, F | 1 |
| Fluss, J | 1 |
| Debus, OM | 1 |
| Köhring, J | 1 |
| Fiedler, B | 1 |
| Franssen, M | 1 |
| Kurlemann, G | 1 |
| Badalian, LO | 1 |
| Temin, PA | 1 |
| Medvedev, MI | 1 |
| Mukhin, KIu | 1 |
| Iskander, MB | 1 |
| Kharlamov, DA | 1 |
| Veselov, NK | 1 |
| Miyazaki, M | 1 |
| Hashimoto, T | 1 |
| Omura, H | 1 |
| Satomura, S | 1 |
| Bando, N | 1 |
| Yoshimoto, T | 1 |
| Tayama, M | 1 |
| Kuroda, Y | 1 |
| Konishi, T | 1 |
| Naganuma, Y | 1 |
| Hongo, K | 1 |
| Murakami, M | 1 |
| Yagi, S | 1 |
| Yamatani, M | 1 |
| Okada, T | 1 |
| Kirkham, FJ | 1 |
| Ebbing, A | 1 |
| Koide, H | 1 |
| Shime, H | 1 |
| Mutoh, K | 1 |
| Okuno, T | 1 |
| Mitsuyoshi, I | 1 |
| Hayakawa, T | 1 |
| Hamada, Y | 1 |
| Mikawa, H | 1 |
| Hoppen, T | 1 |
| Elger, CE | 1 |
| Bartmann, P | 1 |
| Gaily, E | 1 |
| Liukkonen, E | 1 |
| Paetau, R | 1 |
| Rekola, R | 1 |
| Granström, ML | 1 |
| Aucamp, AK | 1 |
| Trompetter-van Woerden, ML | 1 |
| van der Zwan, A | 1 |
| Meldrum, BS | 1 |
| Anlezark, G | 1 |
| Balzamo, E | 1 |
| Horton, RW | 1 |
| Trimble, M | 1 |
| Papazian, O | 1 |
| Tatzer, E | 1 |
| Groh, C | 1 |
| Müller, R | 1 |
| Lischka, A | 1 |
2 reviews available for carbamazepine and Spasms, Infantile
| Article | Year |
|---|---|
Comparative efficacy of antiepileptic drugs in children and adolescents: A network meta-analysis.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Carbamazepine; Ch | 2018 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, | 1979 |
4 trials available for carbamazepine and Spasms, Infantile
| Article | Year |
|---|---|
Add-on treatment with pyridoxine and sulthiame in 12 infants with West syndrome: an open clinical study.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Humans; Infant; Male; Pyridoxine; Spasms, | 2002 |
[The enkorat treatment of infantile spasms and the Lennox-Gastaut syndrome].
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsy; E | 1994 |
Infantile spasms: diagnosis and assessment of treatment response by video-EEG.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Brain; Carbamazepine; Clobazam; Electroenceph | 2001 |
[Experiences with sodium 2-propyl valerate (Depakine) in the treatment of epilepsy].
Topics: Adolescent; Adult; Aged; Carbamazepine; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Clinica | 1977 |
16 other studies available for carbamazepine and Spasms, Infantile
| Article | Year |
|---|---|
Pointed rhythmic theta waves: a unique EEG pattern in KCNQ2-related neonatal epileptic encephalopathy.
Topics: Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Female; Humans; Infant, Newborn; KCNQ | 2017 |
Response to Carbamazepine in KCNQ2 Related Early Infantile Epileptic Encephalopathy.
Topics: Carbamazepine; Electroencephalography; Exons; Genetic Predisposition to Disease; Humans; KCNQ2 Potas | 2019 |
Successful treatment of early myoclonic encephalopathy using lidocaine and carbamazepine.
Topics: Anesthetics, Local; Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Epilepsy, Tonic-C | 2013 |
Epileptic spasms without hypsarrhythmia in infancy and childhood: tonic spasms as a seizure type.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Epilepsies, Partial; Humans; Infant; Male; Oxcarba | 2015 |
Efficacy of sodium channel blockers in SCN2A early infantile epileptic encephalopathy.
Topics: Anticonvulsants; Brain; Carbamazepine; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Ma | 2017 |
Possible induction of West syndrome by oxcarbazepine therapy in a patient with complex partial seizures.
Topics: Anticonvulsants; Carbamazepine; Epilepsy, Complex Partial; Female; Humans; Infant; Oxcarbazepine; Sp | 2012 |
Ohtahara syndrome or early-onset West syndrome? A case with overlapping features and favorable response to vigabatrin.
Topics: Anticonvulsants; Carbamazepine; Drug Resistance; Electroencephalography; Humans; Infant; Male; Neuro | 2012 |
Infantile spasms with predominantly unilateral cerebral abnormalities.
Topics: Carbamazepine; Cerebral Cortex; Electroencephalography; Evoked Potentials, Auditory, Brain Stem; Evo | 1994 |
Discontinuation of antiepileptic drug in childhood epilepsy: evaluation of the differences between epileptic syndromes.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Administration Schedule; E | 1994 |
Case summary: Kate.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Brain Neoplasms; Carbamazepine; Child; Child, Preschoo | 1994 |
West syndrome with cerebellar porencephalus.
Topics: Age of Onset; Carbamazepine; Cerebellar Diseases; Child; Child, Preschool; Cysts; Electroencephalogr | 1993 |
Induction of tonic spasms by carbamazepine: observations on 2 infants.
Topics: Carbamazepine; Child, Preschool; Dose-Response Relationship, Drug; Electroencephalography; Epilepsie | 1993 |
Carbamazepine in phenobarbital-nonresponders: experience with ten preterm infants.
Topics: Administration, Oral; Anticonvulsants; Carbamazepine; Electroencephalography; Female; Follow-Up Stud | 2001 |
Photically induced epilepsy in Papio papio as a model for drug studies.
Topics: Acetylcholine; Animals; Carbamazepine; Clonazepam; Diazepam; Disease Models, Animal; Dopamine; Dose- | 1975 |
Common epileptic syndromes in children.
Topics: Adolescent; Adrenocorticotropic Hormone; Carbamazepine; Child; Child, Preschool; Electroencephalogra | 1991 |
Carbamazepine and benzodiazepines in combination--a possibility to improve the efficacy of treatment of patients with 'intractable' infantile spasms?
Topics: Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combination; Female; Follow-Up Stu | 1987 |