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carbamazepine and Serotonin Syndrome

carbamazepine has been researched along with Serotonin Syndrome in 4 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research Excerpts

ExcerptRelevanceReference
" We present a case of serotonin syndrome, which was precipitated by this medicine in a patient who had been predisposed by long-term treatment with sertraline, a selective serotonin reuptake inhibitor."7.78Fatal serotonin syndrome precipitated by oxcarbazepine in a patient using an selective serotonin reuptake inhibitor. ( Dardis, C; Ly, V; Omoregie, E, 2012)
" We present a case of serotonin syndrome, which was precipitated by this medicine in a patient who had been predisposed by long-term treatment with sertraline, a selective serotonin reuptake inhibitor."3.78Fatal serotonin syndrome precipitated by oxcarbazepine in a patient using an selective serotonin reuptake inhibitor. ( Dardis, C; Ly, V; Omoregie, E, 2012)
"Lamotrigine is a novel anticonvulsant drug which also stabilises mood in bipolar illness via an unknown mechanism."1.30Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats. ( Hagan, RM; Higgins, GA; Kirkby, D; Southam, E, 1998)
"The serotonin syndrome is a rare, but potentially fatal complication to treatment with serotonin reuptake inhibitors."1.30[Serotonin syndrome with fatal outcome caused by selective serotonin reuptake inhibitors]. ( Apelland, T; Dietrichson, T; Gedde-Dahl, T, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Prakash, S1
Rathore, C1
Rana, K1
Patel, H1
Dardis, C1
Omoregie, E1
Ly, V1
Southam, E1
Kirkby, D1
Higgins, GA1
Hagan, RM1
Apelland, T1
Gedde-Dahl, T1
Dietrichson, T1

Reviews

1 review available for carbamazepine and Serotonin Syndrome

ArticleYear
Antiepileptic drugs and serotonin syndrome- A systematic review of case series and case reports.
    Seizure, 2021, Volume: 91

    Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Middle Aged; Oxcarbazepine; Serotonin Syndrom

2021

Other Studies

3 other studies available for carbamazepine and Serotonin Syndrome

ArticleYear
Fatal serotonin syndrome precipitated by oxcarbazepine in a patient using an selective serotonin reuptake inhibitor.
    The neurologist, 2012, Volume: 18, Issue:4

    Topics: Aged, 80 and over; Analgesics; Antihypertensive Agents; Atrial Fibrillation; Bronchodilator Agents;

2012
Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats.
    European journal of pharmacology, 1998, Sep-25, Volume: 358, Issue:1

    Topics: Acetates; Amines; Animals; Anticonvulsants; Biogenic Amines; Blood Platelets; Brain; Carbamazepine;

1998
[Serotonin syndrome with fatal outcome caused by selective serotonin reuptake inhibitors].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1999, Feb-20, Volume: 119, Issue:5

    Topics: Anticonvulsants; Antipsychotic Agents; Butyrophenones; Carbamazepine; Drug Interactions; Drug Therap

1999