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carbamazepine and Renal Insufficiency

carbamazepine has been researched along with Renal Insufficiency in 5 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.

Research Excerpts

ExcerptRelevanceReference
"Epileptic patients receiving medications such as phenytoin or phenobarbital have been noted to have an exceedingly low incidence of myocardial infarction, but children treated with carbamazepine have shown alteration of their serum lipid profile that could predispose them to atherosclerosis."7.72Epilepsy, atherosclerosis, myocardial infarction, and carbamazepine. ( de Chadarévian, JP; Katsetos, CD; Legido, A; Miles, DK, 2003)
"To the best of our knowledge, this is the first published case report implicating carbamazepine as the cause of anemia associated with bone marrow hypercellularity and dyserythropoietic changes, instead of hypocellularity and reduction of erythroid precursors."7.70Severe multisystemic hypersensitivity reaction to carbamazepine including dyserythropoietic anemia. ( Corrocher, R; Girelli, DG; Lombardi, SM, 1999)
"Epileptic patients receiving medications such as phenytoin or phenobarbital have been noted to have an exceedingly low incidence of myocardial infarction, but children treated with carbamazepine have shown alteration of their serum lipid profile that could predispose them to atherosclerosis."3.72Epilepsy, atherosclerosis, myocardial infarction, and carbamazepine. ( de Chadarévian, JP; Katsetos, CD; Legido, A; Miles, DK, 2003)
"To the best of our knowledge, this is the first published case report implicating carbamazepine as the cause of anemia associated with bone marrow hypercellularity and dyserythropoietic changes, instead of hypocellularity and reduction of erythroid precursors."3.70Severe multisystemic hypersensitivity reaction to carbamazepine including dyserythropoietic anemia. ( Corrocher, R; Girelli, DG; Lombardi, SM, 1999)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tutor-Crespo, MJ1
Hermida, J1
Tutor, JC1
de Chadarévian, JP1
Legido, A1
Miles, DK1
Katsetos, CD1
Haase, MR1
Lombardi, SM1
Girelli, DG1
Corrocher, R1
Hurkacz, M1
Wiela-Hojeńska, A1
Orzechowska-Juzwenko, K1
Kozik, A1
Unolt, J1

Other Studies

5 other studies available for carbamazepine and Renal Insufficiency

ArticleYear
Relative proportions of serum carbamazepine and its pharmacologically active 10,11-epoxy derivative: effect of polytherapy and renal insufficiency.
    Upsala journal of medical sciences, 2008, Volume: 113, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Child, Preschool;

2008
Epilepsy, atherosclerosis, myocardial infarction, and carbamazepine.
    Journal of child neurology, 2003, Volume: 18, Issue:2

    Topics: Anticonvulsants; Autopsy; Carbamazepine; Child; Coronary Artery Disease; Epilepsy; Fatal Outcome; Hu

2003
Carbamazepine-induced hepatorenal failure in a child.
    Pharmacotherapy, 1999, Volume: 19, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Child; Humans; Liver Failure; Male; Renal Insufficiency

1999
Severe multisystemic hypersensitivity reaction to carbamazepine including dyserythropoietic anemia.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:5

    Topics: Aged; Anemia; Anticonvulsants; Carbamazepine; Cell Size; Dermatitis, Exfoliative; Drug Hypersensitiv

1999
[Monitoring of renal function in epileptic children and teenagers treated with valproic acid or carbamazepine in concomitant therapy with tiagabine].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2001, Volume: 11, Issue:66

    Topics: Acetylglucosaminidase; Adolescent; Adult; Anticonvulsants; beta 2-Microglobulin; Carbamazepine; Case

2001