carbamazepine has been researched along with Pregnancy in 376 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This paper aims to undertake a comprehensive review regarding the possible risks of four classical (phenytoin, carbamazepine, phenobarbital, and valproate) and two newer (lamotrigine and levetiracetam) AEDs during pregnancy." | 9.12 | Use of Phenytoin, Phenobarbital Carbamazepine, Levetiracetam Lamotrigine and Valproate in Pregnancy and Breastfeeding: Risk of Major Malformations, Dose-dependency, Monotherapy vs Polytherapy, Pharmacokinetics and Clinical Implications. ( Demir, O; Kaplan, YC, 2021) |
| "Our objective was to evaluate the patterns of malformations in children exposed in utero to phenytoin (DPH) and carbamazepine (CBZ) monotherapy, and to compare them prospectively with matched mother-child pairs exposed to nonteratogens, and to separate the effects of antiepileptic drugs (AEDs) from those of epilepsy by collecting groups of untreated epileptics and those treated with DPH and CBZ for conditions other than epilepsy." | 9.08 | Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications. ( Chitayat, D; Farkas, LD; Koren, G; Nulman, I; Scolnik, D, 1997) |
| "Lamotrigine is used in pregnancy to control epilepsy and mood disorders." | 8.95 | Pregnancy Outcomes Following In Utero Exposure to Lamotrigine: A Systematic Review and Meta-Analysis. ( Adams-Webber, T; Barzilay, E; Leibson, T; Nulman, I; Pariente, G; Shulman, T, 2017) |
| " However, a particular association of valproate and carbamazepine with neural tube defects (NTDs)--specifically, with spina bifida aperta (SB)--has been identified." | 8.82 | Management issues for women with epilepsy: neural tube defects and folic acid supplementation. ( Yerby, MS, 2003) |
| " In this review, the safety of the newer AED oxcarbazepine during pregnancy is assessed based on published pregnancy outcome data." | 8.82 | Safety of the newer antiepileptic drug oxcarbazepine during pregnancy. ( Montouris, G, 2005) |
| "To check for an association between carbamazepine (CBZ) use by the mother during pregnancy and congenital eye malformations (i." | 8.81 | Is there an association between maternal carbamazepine use during pregnancy and eye malformations in the child? ( Cornel, MC; Kroes, HY; Reefhuis, J, 2002) |
| "This study was carried out to determine changes over time in use of folic acid, anti-epileptic drugs (AED), seizures during pregnancy and malformation rate over two decades in women with epilepsy enrolled in the Kerala registry of Epilepsy and Pregnancy (KREP)." | 7.96 | Anti-epileptic drug and folic acid usage during pregnancy, seizure and malformation outcomes: Changes over two decades in the Kerala Registry of Epilepsy and Pregnancy. ( A S, R; Baishya, J; Jose, M; Keni, RR; Sankara Sarma, P; Thomas, SV, 2020) |
| "The aims of this study were to characterize the alterations in total and free carbamazepine (CBZ) and in total and free carbamazepine-epoxide (CBZ-EPO) clearances during pregnancy, to calculate the change in free fractions of CBZ and CBZ-EPO during pregnancy, and to determine whether seizure worsening is associated with a low ratio to nonpregnant baseline concentration of total or free CBZ or CBZ-EPO." | 7.80 | Carbamazepine clearance and seizure stability during pregnancy. ( Johnson, EL; Knight, B; Newman, ML; Newport, DJ; Pennell, PB; Ritchie, JC; Stowe, ZN, 2014) |
| "Oxcarbazepine is an antiepileptic agent that has been used during pregnancy, although its safety during pregnancy has not been sufficiently established." | 7.79 | In utero oxcarbazepine and a withdrawal syndrome, anomalies, and hyponatremia. ( Klinger, G; Merlob, P; Rolnitsky, A, 2013) |
| "We report a stillborn, GA/LMP = 37 weeks, delivered by an epileptic woman, who received in the first four months of pregnancy phenobarbital (PH) 0." | 7.79 | Sirenomelia after phenobarbital and carbamazepine therapy in pregnancy. ( Brailoiu, CG; Cernea, N; Tica, AA; Tica, OS; Tica, VI, 2013) |
| "Similar to valproic acid, carbamazepine increases the risk of neural tube defects; however, it does not increase the risk of other malformations." | 7.78 | Is carbamazepine safe to take during pregnancy? ( Koren, G; Matlow, J, 2012) |
| "Thirteen pregnancies in ten women on oxcarbazepine (OXC) monotherapy and one pregnancy in a woman on OXC and topiramate therapy were retrospectively analyzed." | 7.75 | Seizure deterioration in women treated with oxcarbazepine during pregnancy. ( Hansen-Schwartz, J; Petrenaite, V; Sabers, A, 2009) |
| "To determine potential changes in the plasma concentrations of oxcarbazepine (OXC) and its metabolites during pregnancy and puerperium." | 7.73 | Changes in the disposition of oxcarbazepine and its metabolites during pregnancy and the puerperium. ( Atakli, D; Gatti, G; Mazzucchelli, I; Neve, AL; Onat, FY; Ozkara, C; Perucca, E; Specchio, LM, 2006) |
| " Preceding a planned pregnancy, the patient was switched to oxcarbazepine and tapered off both phenytoin and gabapentin." | 7.73 | Treatment with oxcarbazepine during pregnancy. ( Eisenschenk, S, 2006) |
| "We assessed the concentration of the oxcarbazepine metabolite 10-hydroxycarbazepine (MHD) in nine pregnancies among seven women before, during, and after pregnancy." | 7.73 | Oxcarbazepine concentrations during pregnancy: a retrospective study in patients with epilepsy. ( Christensen, J; Sabers, A; Sidenius, P, 2006) |
| " The boy was exposed to phenytoin, in combination with carbamazepine, during pregnancy." | 7.71 | Chondrodysplasia punctata (CDP) with features of the tibia-metacarpal type and maternal phenytoin treatment during pregnancy. ( Annerén, G; Brandberg, G; Larsson, M; Lönnerholm, T; Wester, U, 2002) |
| "To report a case of transient cholestatic hepatitis occurring in an infant between the third and seventh weeks of life, most likely due to carbamazepine exposure during pregnancy and breast feeding." | 7.71 | Neonatal cholestatic hepatitis from carbamazepine exposure during pregnancy and breast feeding. ( Braegger, CP; Frey, B; Ghelfi, D, 2002) |
| " A metastatic neuroblastoma was detected immediately after birth in a boy born to a 26 year old woman with bipolar disorder, who received carbamazepine (400 mg/day) all through her pregnancy." | 7.70 | Congenital neuroblastoma in a boy born to a woman with bipolar disorder treated with carbamazepine during pregnancy. ( Araujo, H; Baptista, T; Hernández, L; Rada, P, 1998) |
| " The mothers of all for children were treated with carbamazepine during pregnancy." | 7.70 | Eye malformations associated with treatment with carbamazepine during pregnancy. ( Jones, RB; Sutcliffe, AG; Woodruff, G, 1998) |
| "Urinary excretions of carbamazepine, carbamazepine-10,11-epoxide, carbamazepine-10,11-trans-diol, 9-hydroxyacridan and 2- and 3-hydroxycarbamazepine were measured at various stages of pregnancy, and in the post-natal period, in ten epileptic women, six of whom took no other enzyme-inducing anticonvulsant and four of whom took such co-medication." | 7.69 | Metabolism of carbamazepine and co-administered anticonvulsants during pregnancy. ( Bernus, I; Dickinson, RG; Eadie, MJ; Hooper, WD, 1995) |
| "The purpose of the study was to assess whether there was an increased rate of congenital anomalies or significant developmental delay in infants of women with epilepsy who had been treated with carbamazepine during pregnancy." | 7.69 | Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy. ( Cohen, E; Ornoy, A, 1996) |
| "We report a 3-week-old boy with cholestatic hepatitis, most likely due to carbamazepine exposure during pregnancy and breastfeeding." | 7.68 | Transient cholestatic hepatitis in a neonate associated with carbamazepine exposure during pregnancy and breast-feeding. ( Frey, B; Musy, JP; Schubiger, G, 1990) |
| "An epileptic patient whose seizures were controlled with carbamazepine and primidone was followed throughout pregnancy and lactation." | 7.66 | Carbamazepine levels in pregnancy and lactation. ( Blake, DA; Freeman, JM; Luff, RD; Niebyl, JR, 1979) |
| "Oxcarbazepine is a second-generation antiepileptic drug that is used to treat partial seizures." | 6.55 | In Utero Oxcarbazepine Exposure and Neonatal Abstinence Syndrome: Case Report and Brief Review of the Literature. ( Chen, CY; Cui, YM; Feng, Q; Li, X; Ma, LY; Wu, PH; Zhou, Y, 2017) |
| "Phenobarbital was associated with a higher rate of drug withdrawal although there was no evidence to suggest that phenobarbital caused more adverse events compared to carbamazepine, valproic acid or phenytoin." | 6.47 | Side effects of phenobarbital in epilepsy: a systematic review. ( Li, YP; Zeng, LN; Zhang, LL, 2011) |
| "Epilepsy treatment during pregnancy is still challenging." | 5.72 | Levetiracetam, lamotrigine and carbamazepine: which monotherapy during pregnancy? ( Castelli, A; Del Bianco, C; Izzi, F; Liguori, C; Manfredi, N; Mari, L; Mercuri, NB; Placidi, F; Romigi, A; Tombini, M; Ulivi, M, 2022) |
| "LEV provides similar seizure control to that of the older AEDs, and it is more effective and better than LTG." | 5.48 | Comparative study of antiepileptic drug use during pregnancy over a period of 12 years in Spain. Efficacy of the newer antiepileptic drugs lamotrigine, levetiracetam, and oxcarbazepine. ( Escartin Siquier, A; Forcadas Berdusan, M; Martin Moro, M; Martinez Ferri, M; Peña Mayor, P; Perez López-Fraile, I, 2018) |
| "Carbamazepine and water were given by gastric gavage throughout gestational period." | 5.42 | Teratogenic effect of Carbamazepine use during pregnancy in the mice. ( El-Kenawy, Ael-M; Elshama, SS; Osman, HE, 2015) |
| " In case of breakthrough seizures or increased seizure frequency, dosage adjustment of both drugs may be required." | 5.36 | Drug monitoring of lamotrigine and oxcarbazepine combination during pregnancy. ( de Haan, GJ; Edelbroek, P; Lindhout, D; Sander, JW; Wegner, I, 2010) |
| "Lamotrigine (LTG) has been used in epilepsia patients for treatment of partial seizures." | 5.35 | Unilateral radius aplasia due to lamotrigine and oxcarbazepine use in pregnancy. ( Cetinkaya, M; Köksal, N; Ozkan, H, 2008) |
| "Pregnant women with epilepsy on one or more of the following AEDs: lamotrigine, carbamazepine, phenytoin or levetiracetam." | 5.27 | AntiEpileptic drug Monitoring in PREgnancy (EMPiRE): a double-blind randomised trial on effectiveness and acceptability of monitoring strategies. ( Bagary, M; Coleman, J; D'Amico, M; Denny, E; Dodds, J; Eldridge, S; Greenhill, L; Hard, K; Kelso, A; Khan, KS; Marlin, N; McCorry, D; Middleton, L; Moss, N; Newton, S; Pirie, A; Pullen, A; Rikunenko, R; Roberts, T; Rogozińska, E; Thangaratinam, S; Weckesser, A, 2018) |
| "Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment." | 5.27 | Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983) |
| " This paper aims to undertake a comprehensive review regarding the possible risks of four classical (phenytoin, carbamazepine, phenobarbital, and valproate) and two newer (lamotrigine and levetiracetam) AEDs during pregnancy." | 5.12 | Use of Phenytoin, Phenobarbital Carbamazepine, Levetiracetam Lamotrigine and Valproate in Pregnancy and Breastfeeding: Risk of Major Malformations, Dose-dependency, Monotherapy vs Polytherapy, Pharmacokinetics and Clinical Implications. ( Demir, O; Kaplan, YC, 2021) |
| "Our objective was to evaluate the patterns of malformations in children exposed in utero to phenytoin (DPH) and carbamazepine (CBZ) monotherapy, and to compare them prospectively with matched mother-child pairs exposed to nonteratogens, and to separate the effects of antiepileptic drugs (AEDs) from those of epilepsy by collecting groups of untreated epileptics and those treated with DPH and CBZ for conditions other than epilepsy." | 5.08 | Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications. ( Chitayat, D; Farkas, LD; Koren, G; Nulman, I; Scolnik, D, 1997) |
| "Lamotrigine is used in pregnancy to control epilepsy and mood disorders." | 4.95 | Pregnancy Outcomes Following In Utero Exposure to Lamotrigine: A Systematic Review and Meta-Analysis. ( Adams-Webber, T; Barzilay, E; Leibson, T; Nulman, I; Pariente, G; Shulman, T, 2017) |
| " Oxcarbazepine and lamotrigine were associated with increased occurrence of autism." | 4.95 | Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta-analysis. ( Cogo, E; D'Souza, J; Finkelstein, Y; Hemmelgarn, BR; Hutton, B; Kealey, R; MacDonald, H; Reynen, E; Rios, P; Soobiah, C; Straus, SE; Thavorn, K; Tricco, AC; Veroniki, AA; Yazdi, F, 2017) |
| "The developmental quotient (DQ) was lower in children exposed to carbamazepine (CBZ) (n = 50) than in children born to women without epilepsy (n = 79); mean difference (MD) of -5." | 4.90 | Treatment for epilepsy in pregnancy: neurodevelopmental outcomes in the child. ( Adab, N; Bromley, R; Greenhalgh, J; Marson, AG; McKay, AJ; Sanniti, A; Tudur Smith, C; Weston, J, 2014) |
| "A systematic search was carried out of electronic databases, reference books and other sources for original research studies which examined the effects of commonly used mood stabilizers (sodium valproate, carbamazepine, lamotrigine and lithium carbonate) on pregnancy outcomes." | 4.86 | Mood stabilizers in pregnancy: a systematic review. ( Buist, A; Galbally, M; Roberts, M, 2010) |
| "To identify specific major congenital malformations associated with use of carbamazepine in the first trimester of pregnancy." | 4.86 | Intrauterine exposure to carbamazepine and specific congenital malformations: systematic review and case-control study. ( de Jong-van den Berg, L; Dolk, H; Garne, E; Jentink, J; Loane, MA; Morris, JK; Wellesley, D, 2010) |
| "Studies have confirmed that the elimination of lamotrigine and the active metabolite of oxcarbazepine is enhanced during pregnancy." | 4.85 | Managing antiepileptic drugs during pregnancy and lactation. ( Sabers, A; Tomson, T, 2009) |
| " However, a particular association of valproate and carbamazepine with neural tube defects (NTDs)--specifically, with spina bifida aperta (SB)--has been identified." | 4.82 | Management issues for women with epilepsy: neural tube defects and folic acid supplementation. ( Yerby, MS, 2003) |
| " In this review, the safety of the newer AED oxcarbazepine during pregnancy is assessed based on published pregnancy outcome data." | 4.82 | Safety of the newer antiepileptic drug oxcarbazepine during pregnancy. ( Montouris, G, 2005) |
| "To check for an association between carbamazepine (CBZ) use by the mother during pregnancy and congenital eye malformations (i." | 4.81 | Is there an association between maternal carbamazepine use during pregnancy and eye malformations in the child? ( Cornel, MC; Kroes, HY; Reefhuis, J, 2002) |
| " The terms used individually and in combination were oxcarbazepine, carbamazepine, epilepsy, and seizures." | 4.81 | Oxcarbazepine, an antiepileptic agent. ( Huff, NA; Kalis, MM, 2001) |
| "The acute and chronic pharmacotherapy of bipolar disorder requires an understanding of the pharmacology of very dissimilar compounds--the mood stabilizers (lithium, carbamazepine and valproate) and several classes of antidepressants." | 4.78 | Pharmacological issues in the treatment of bipolar disorder: focus on mood-stabilizing compounds. ( Ketter, TA; Potter, WZ, 1993) |
| "To investigate whether children born to mothers who used carbamazepine during pregnancy had worse academic performance in adolescence." | 4.31 | Prenatal Carbamazepine Exposure and Academic Performance in Adolescents: A Population-Based Cohort Study. ( Lee, PMY; Li, F; Li, J; Ren, T, 2023) |
| "Findings from this explorative study strengthen the evidence for the warning against the use of valproate in pregnancy and raise concern of risks of specific psychiatric disorders associated with topiramate and levetiracetam." | 4.31 | Prenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders. ( Alvestad, S; Bjørk, MH; Christensen, J; Cohen, JM; Dreier, JW; Furu, K; Gissler, M; Igland, J; Leinonen, MK; Sun, Y; Tomson, T; Zoega, H, 2023) |
| "05) of an increased hazard of fetal malformation associated with exposure to valproate, carbamazepine, topiramate, zonisamide, and with conception after assisted fertilization, but a reduced hazard in the offspring of women who continued to smoke during pregnancy." | 4.31 | Specific fetal malformations following intrauterine exposure to antiseizure medication. ( Eadie, M; Graham, J; Hitchcock, A; Lander, C; O'Brien, T; Perucca, P; Vajda, F, 2023) |
| "Usage during pregnancy of the antiseizure medication (ASM), phenobarbital (PB), carbamazepine (CBZ), and phenytoin (PHT), has been associated with adverse pregnancy outcomes." | 4.12 | Neuropsychological effects in children exposed to anticonvulsant monotherapy during gestation: Phenobarbital, carbamazepine, and phenytoin. ( Adams, J; Carlson, JM; Dhillon, R; Holmes, LB; Janulewicz, PA; Macklin, EA; Phillips, C; Schomer, DL; Tosches, WA, 2022) |
| "This study was carried out to determine changes over time in use of folic acid, anti-epileptic drugs (AED), seizures during pregnancy and malformation rate over two decades in women with epilepsy enrolled in the Kerala registry of Epilepsy and Pregnancy (KREP)." | 3.96 | Anti-epileptic drug and folic acid usage during pregnancy, seizure and malformation outcomes: Changes over two decades in the Kerala Registry of Epilepsy and Pregnancy. ( A S, R; Baishya, J; Jose, M; Keni, RR; Sankara Sarma, P; Thomas, SV, 2020) |
| "Carbamazepine and topiramate both have established potentials for causing teratogenesis, and it is possible that replacement of carbamazepine with a less teratogenic AED, for example levetiracetam, might result in any subsequent depression that occurs in pregnancy being inappropriately attributed to the newly introduced agent." | 3.96 | Antiepileptic drugs and depression during pregnancy in women with epilepsy. ( Eadie, MJ; Graham, JE; Hitchcock, AA; Horgan, D; Lander, CM; Mitchell, J; O'Brien, TJ; Vajda, FJE, 2020) |
| "Intrauterine exposure to anti-epileptic drugs, particularly carbamazepine, may be associated with an increased risk of foetal death during pregnancy." | 3.88 | Anti-epileptic drug exposure and risk of foetal death in utero. ( Eadie, MJ; Graham, J; Hitchcock, AA; Lander, CM; O'Brien, TJ; Vajda, FJE, 2018) |
| " This limitation and high risks of neural tube and other major teratogenic effects, especially of valproate, indicate the need for great caution in the use of valproate and carbamazepine to treat bipolar disorder in women of child-bearing age." | 3.88 | Mood-Stabilizing Anticonvulsants, Spina Bifida, and Folate Supplementation: Commentary. ( Baldessarini, RJ; Patel, N; Viguera, AC, 2018) |
| " Both administrations of CBZ caused a hypothyroidism in dams and fetuses whereas the decreases in serum thyroxine (T4) and triiodothyronine (T3) and increases in serum thyrotropin (TSH) levels were highly significant (LSD; P <0." | 3.85 | Maternal carbamazepine alters fetal neuroendocrine-cytokines axis. ( Ahmed, RG; El-Gareib, AW, 2017) |
| "Carbamazepine is one of the three most frequently prescribed antiepileptic drugs in pregnancy." | 3.83 | Concentrations of carbamazepine and carbamazepine-10,11-epoxide in maternal and umbilical cord blood at birth: Influence of co-administration of valproic acid or enzyme-inducing antiepileptic drugs. ( Brozmanova, H; Grundmann, M; Kacirova, I, 2016) |
| " Here we provide updated results from the UK Epilepsy and Pregnancy Register of the risk of MCMs after monotherapy exposure to valproate, carbamazepine and lamotrigine." | 3.80 | Malformation risks of antiepileptic drug monotherapies in pregnancy: updated results from the UK and Ireland Epilepsy and Pregnancy Registers. ( Campbell, E; Craig, J; Delanty, N; Hunt, SJ; Irwin, B; Kennedy, F; Liggan, B; Morrison, PJ; Morrow, J; Parsons, L; Russell, A; Smithson, WH, 2014) |
| "The aims of this study were to characterize the alterations in total and free carbamazepine (CBZ) and in total and free carbamazepine-epoxide (CBZ-EPO) clearances during pregnancy, to calculate the change in free fractions of CBZ and CBZ-EPO during pregnancy, and to determine whether seizure worsening is associated with a low ratio to nonpregnant baseline concentration of total or free CBZ or CBZ-EPO." | 3.80 | Carbamazepine clearance and seizure stability during pregnancy. ( Johnson, EL; Knight, B; Newman, ML; Newport, DJ; Pennell, PB; Ritchie, JC; Stowe, ZN, 2014) |
| "Maternal epilepsy treated with carbamazepine and migraine were found to be associated with higher risk of ventricular septal defect; panic disorders were associated with higher risk of hypoplastic left heart; type I diabetes mellitus was associated with higher risk of coarctation of the aorta; chronic hypertension was associated with higher risk of ventricular septal defect, common atrioventricular canal and common truncus; and paroxysmal supraventricular tachycardia was associated with higher risk of atrial septal defect secundum, common atrioventricular canal and ventricular septal defect." | 3.80 | Association of certain chronic maternal diseases with the risk of specific congenital heart defects: a population-based study. ( Czeizel, AE; Gerencsér, B; Szabó, I; Vereczkey, A, 2014) |
| "Oxcarbazepine is an antiepileptic agent that has been used during pregnancy, although its safety during pregnancy has not been sufficiently established." | 3.79 | In utero oxcarbazepine and a withdrawal syndrome, anomalies, and hyponatremia. ( Klinger, G; Merlob, P; Rolnitsky, A, 2013) |
| "We report a stillborn, GA/LMP = 37 weeks, delivered by an epileptic woman, who received in the first four months of pregnancy phenobarbital (PH) 0." | 3.79 | Sirenomelia after phenobarbital and carbamazepine therapy in pregnancy. ( Brailoiu, CG; Cernea, N; Tica, AA; Tica, OS; Tica, VI, 2013) |
| "To analyze seizure control, dose adjustments, and other changes of antiepileptic drug (AED) treatment during pregnancy in a large cohort of women with epilepsy entering pregnancy on monotherapy with carbamazepine, lamotrigine, phenobarbital, or valproate." | 3.79 | Seizure control and treatment changes in pregnancy: observations from the EURAP epilepsy pregnancy registry. ( Battino, D; Bonizzoni, E; Craig, J; Lindhout, D; Perucca, E; Sabers, A; Tomson, T; Vajda, F, 2013) |
| "Similar to valproic acid, carbamazepine increases the risk of neural tube defects; however, it does not increase the risk of other malformations." | 3.78 | Is carbamazepine safe to take during pregnancy? ( Koren, G; Matlow, J, 2012) |
| "We present a case of a woman who used topiramate (100 mg) and oxcarbazepine (300 mg) continuously during pregnancy." | 3.78 | Multiple fetal anomalies in association with topiramate and oxcarbezepine treatment. ( Aksoy, F; Aydin, Y; Bakkaloglu, D; Sen, C; Uludag, S; Yilmaz, O, 2012) |
| "Based on epidemiological data it is advised to whenever possible avoid valproic acid during pregnancy." | 3.78 | Economic evaluation of anti-epileptic drug therapies with specific focus on teratogenic outcomes. ( Boersma, C; de Jong-van den Berg, LT; Jentink, J; Postma, MJ, 2012) |
| "To determine the frequency of malformations among infants born to women who had taken lamotrigine or carbamazepine as part of polytherapy during the first trimester of pregnancy." | 3.77 | Fetal effects of anticonvulsant polytherapies: different risks from different drug combinations. ( Hernandez-Diaz, S; Holmes, LB; Mittendorf, R; Shen, A; Smith, CR, 2011) |
| " To assess the impact of influencing AED prescribing practices on spina bifida and cleft palate we searched the literature for estimates of the association between valproic acid or carbamazepine use during pregnancy and these defects and summarized the associations using meta-analyses." | 3.77 | Influencing clinical practice regarding the use of antiepileptic medications during pregnancy: modeling the potential impact on the prevalences of spina bifida and cleft palate in the United States. ( Boulet, SL; Broussard, CS; Devine, OJ; Duwe, KN; Flak, AL; Gilboa, SM; Honein, MA; Moore, CA; Werler, MM, 2011) |
| "Valproic acid, which current guidelines suggest should be avoided in pregnancy, was most notable in terms of strength and breadth of its associations." | 3.77 | Use of antiepileptic medications in pregnancy in relation to risks of birth defects. ( Ahrens, KA; Anderka, MT; Bosco, JL; Gilboa, SM; Holmes, LB; Mitchell, AA; Werler, MM, 2011) |
| " The carbamazepine concentration in breast milk of one epilepsy maternal patient was assayed by high performance liquid chromatography, and the literature was reviewed to find the nursing evidence in the use of cabamazepine." | 3.76 | [A case report of monitoring on carbamazepine in breast feeding woman]. ( Wei, Y; Xiong, X; Yang, L; Zhai, SD; Zhao, M; Zhou, Y, 2010) |
| " Between 1999 and 2004, we enrolled pregnant women with epilepsy who were taking a single AED (carbamazepine, lamotrigine, phenytoin, or valproate)." | 3.76 | Effects of breastfeeding in children of women taking antiepileptic drugs. ( Baker, GA; Browning, N; Clayton-Smith, J; Cohen, M; Combs-Cantrell, DT; Kalayjian, LA; Kanner, A; Liporace, JD; Loring, DW; Meador, KJ; Pennell, PB; Privitera, M, 2010) |
| "Thirteen pregnancies in ten women on oxcarbazepine (OXC) monotherapy and one pregnancy in a woman on OXC and topiramate therapy were retrospectively analyzed." | 3.75 | Seizure deterioration in women treated with oxcarbazepine during pregnancy. ( Hansen-Schwartz, J; Petrenaite, V; Sabers, A, 2009) |
| "Between 1999 and 2004, we enrolled pregnant women with epilepsy who were taking a single antiepileptic agent (carbamazepine, lamotrigine, phenytoin, or valproate) in a prospective, observational, multicenter study in the United States and the United Kingdom." | 3.75 | Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs. ( Baker, GA; Browning, N; Clayton-Smith, J; Cohen, M; Combs-Cantrell, DT; Kalayjian, LA; Kanner, A; Liporace, JD; Loring, DW; Meador, KJ; Pennell, PB; Privitera, M, 2009) |
| " We point out that during the pregnancy 4 of these 5 women with epilepsy had taken valproates, and the other one--carbamazepine." | 3.75 | [Fetal malformations in women with epilepsy]. ( Bozhinov, P; Bozhinova, C; Markova, C, 2009) |
| "This substudy of the Neurodevelopmental Effects of Antiepileptic Drugs investigation enrolled pregnant women with epilepsy on AED monotherapy (carbamazepine, lamotrigine, and valproate)." | 3.75 | A prospective study of cognitive fluency and originality in children exposed in utero to carbamazepine, lamotrigine, or valproate monotherapy. ( Gaillard, WD; McVearry, KM; Meador, KJ; VanMeter, J, 2009) |
| "(1) Numerous follow-up studies of pregnancies in women with epilepsy show that valproic acid is more teratogenic than other antiepileptics." | 3.75 | Valproic acid: long-term effects on children exposed in utero. ( , 2009) |
| "An increased risk for isolated CL/P was found in cases born to mothers treated with amoxicillin, phenytoin, oxprenolol, and thiethylperazine during the second and third month of pregnancy, i." | 3.74 | Drug treatment during pregnancy and isolated orofacial clefts in hungary. ( Czeizel, AE; Métneki, J; Puhó, EH; Szunyogh, M, 2007) |
| " By contrast, offspring of rats exposed to carbamazepine (which at the dose used produced low plasma concentrations) or to generalized convulsive seizures showed no clear-cut evidence of dysplasias." | 3.74 | Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias. ( Ben-Ari, Y; Depaulis, A; Jorquera, I; Manent, JB; Mazzucchelli, I; Perucca, E; Represa, A, 2007) |
| "Children exposed during pregnancy to the anticonvulsant drugs phenytoin, phenobarbital, and carbamazepine as monotherapy and polytherapy have an increased frequency of midface and digit hypoplasia." | 3.73 | The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs. ( Coull, BA; Dorfman, J; Holmes, LB; Rosenberger, PB, 2005) |
| "To determine potential changes in the plasma concentrations of oxcarbazepine (OXC) and its metabolites during pregnancy and puerperium." | 3.73 | Changes in the disposition of oxcarbazepine and its metabolites during pregnancy and the puerperium. ( Atakli, D; Gatti, G; Mazzucchelli, I; Neve, AL; Onat, FY; Ozkara, C; Perucca, E; Specchio, LM, 2006) |
| " Preceding a planned pregnancy, the patient was switched to oxcarbazepine and tapered off both phenytoin and gabapentin." | 3.73 | Treatment with oxcarbazepine during pregnancy. ( Eisenschenk, S, 2006) |
| "We assessed the concentration of the oxcarbazepine metabolite 10-hydroxycarbazepine (MHD) in nine pregnancies among seven women before, during, and after pregnancy." | 3.73 | Oxcarbazepine concentrations during pregnancy: a retrospective study in patients with epilepsy. ( Christensen, J; Sabers, A; Sidenius, P, 2006) |
| "To investigate the effect of antiepileptic drugs, especially carbamazepine and valproate, on intelligence in prenatally exposed children of mothers with epilepsy." | 3.72 | Normal intelligence in children with prenatal exposure to carbamazepine. ( Bardy, A; Gaily, E; Granström, ML; Hiilesmaa, V; Isoaho, M; Kaaja, E; Kantola-Sorsa, E; Kotila, M; Matila, R; Nylund, T, 2004) |
| "The purpose of this study was to determine if there are any correlations between carbamazepine serum levels of epileptic mothers during pregnancy and the brainstem auditory evoked potentials in their infants as an index of drug neurotoxicity in newborns exposed prenatally." | 3.71 | Effects of prenatal exposure to carbamazepine on brainstem auditory evoked potentials in infants of epileptic mothers. ( Belmont, A; Garza, S; Ibarra, J; López, V; Poblano, A; Rosas, Y; Sosa, J, 2002) |
| " The boy was exposed to phenytoin, in combination with carbamazepine, during pregnancy." | 3.71 | Chondrodysplasia punctata (CDP) with features of the tibia-metacarpal type and maternal phenytoin treatment during pregnancy. ( Annerén, G; Brandberg, G; Larsson, M; Lönnerholm, T; Wester, U, 2002) |
| "We selected all subjects who enrolled in the California Teratogen Information Service (CTIS) pregnancy outcome study for prenatal exposure to carbamazepine or valproic acid between 1990 and 1997 and who received prenatal care through Kaiser Permanente of Southern California (n = 13)." | 3.71 | Selection bias in Teratology Information Service pregnancy outcome studies. ( Chambers, CD; Johnson, KA; Jones, KL; Weber, PA, 2001) |
| "To report a case of transient cholestatic hepatitis occurring in an infant between the third and seventh weeks of life, most likely due to carbamazepine exposure during pregnancy and breast feeding." | 3.71 | Neonatal cholestatic hepatitis from carbamazepine exposure during pregnancy and breast feeding. ( Braegger, CP; Frey, B; Ghelfi, D, 2002) |
| " A metastatic neuroblastoma was detected immediately after birth in a boy born to a 26 year old woman with bipolar disorder, who received carbamazepine (400 mg/day) all through her pregnancy." | 3.70 | Congenital neuroblastoma in a boy born to a woman with bipolar disorder treated with carbamazepine during pregnancy. ( Araujo, H; Baptista, T; Hernández, L; Rada, P, 1998) |
| " The mothers of all for children were treated with carbamazepine during pregnancy." | 3.70 | Eye malformations associated with treatment with carbamazepine during pregnancy. ( Jones, RB; Sutcliffe, AG; Woodruff, G, 1998) |
| "We present an uncommon severe first branchial arch congenital malformation, in which complete unilateral bony fusion between the maxillary and mandibular processes was found in a newborn exposed to carbamazepine medication all through pregnancy." | 3.70 | Congenital unilateral fusion of the maxilla and mandible. ( Haddad, IK; Salah, S; Shamo'on, H, 1999) |
| "Twenty epileptic women were treated with valproate only during pregnancy and two were treated with valproate and carbamazepine." | 3.70 | Neonatal hypoglycaemia and withdrawal symptoms after exposure in utero to valproate. ( Ebbesen, F; Holsteen, V; Hoseth, E; Joergensen, A; Kaad, PH; Moeller, M; Rix, M, 2000) |
| "To compare pregnancy outcome prospectively after phenytoin and carbamazepine monotherapy with outcome in matched mother-child pairs exposed to nonteratogens to evaluate the relative fetal safety of these drugs." | 3.69 | Neurodevelopment of children exposed in utero to phenytoin and carbamazepine monotherapy. ( Ashby, P; Czuchta, D; Einarson, T; Gardner, HA; Gladstone, D; Gladstone, R; Nulman, I; Rovet, J; Scolnik, D; Weksberg, R, 1994) |
| "Urinary excretions of carbamazepine, carbamazepine-10,11-epoxide, carbamazepine-10,11-trans-diol, 9-hydroxyacridan and 2- and 3-hydroxycarbamazepine were measured at various stages of pregnancy, and in the post-natal period, in ten epileptic women, six of whom took no other enzyme-inducing anticonvulsant and four of whom took such co-medication." | 3.69 | Metabolism of carbamazepine and co-administered anticonvulsants during pregnancy. ( Bernus, I; Dickinson, RG; Eadie, MJ; Hooper, WD, 1995) |
| " The mother had taken clonazepam, a benzodiazepine, and carbamazepine during the entire pregnancy for epilepsy." | 3.69 | Paralytic ileus in a fetus-neonate after maternal intake of benzodiazepine. ( Haeusler, MC; Hoellwarth, ME; Holzer, P, 1995) |
| "The purpose of the study was to assess whether there was an increased rate of congenital anomalies or significant developmental delay in infants of women with epilepsy who had been treated with carbamazepine during pregnancy." | 3.69 | Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy. ( Cohen, E; Ornoy, A, 1996) |
| "5 months of pregnancy then carbamazepine 400 mg LP x 2/day, raised to 600 mg LP x 2/day at the 25th week of gestation because of epileptic crisis." | 3.69 | [Carbamazepine and vigabatrin in epileptic pregnant woman and side effects in the newborn infant]. ( Aboulghit, H; Beust, M; Kayemba Kay'S, S; Mourtada, A; Voisin, M, 1997) |
| "The first case describes a 15-year-old boy who received valproic acid and carbamazepine for partial seizures." | 3.68 | Loss of seizure control associated with generic substitution of carbamazepine. ( Arazi, R; Hale, BC; Pickering, PR; Welty, TE, 1992) |
| "The effects of antiepileptic drugs (AED) on infants during pregnancy and delivery were studied in a total of 82 epileptic mothers on various monotherapies; 29 cases receiving valproic acid (VPA), 20 receiving phenytoin (PHT), 18 on carbamazepine (CBZ) and 15 on phenobarbital (PB)." | 3.68 | [Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital]. ( Ishikawa, S; Izumi, M; Okada, H; Takeda, A; Tanaka, H, 1991) |
| "A girl was born to a mother who had undergone treatment for epilepsy with carbamazepine during pregnancy." | 3.68 | Teratogenic effect of carbamazepine. ( Vestermark, S; Vestermark, V, 1991) |
| "We report a 3-week-old boy with cholestatic hepatitis, most likely due to carbamazepine exposure during pregnancy and breastfeeding." | 3.68 | Transient cholestatic hepatitis in a neonate associated with carbamazepine exposure during pregnancy and breast-feeding. ( Frey, B; Musy, JP; Schubiger, G, 1990) |
| " Fifty-two children had been exposed to phenytoin monotherapy, 19 to carbamazepine monotherapy, 27 to drug combinations including barbiturates, 29 to other drug combinations, and 17 children had not been exposed to antiepileptic drugs (AEDs) during pregnancy." | 3.68 | Head circumference in children of epileptic mothers: contributions of drug exposure and genetic background. ( Bardy, AH; Gaily, EK; Granström, ML; Hiilesmaa, VK, 1990) |
| "Serum concentrations of the main vitamin D metabolites and of calcium, phosphate, and alkaline phosphatase were determined in each of the three trimesters of pregnancy and in simultaneously obtained maternal and cord blood at delivery in 22 epileptic women treated with diphenylhydantoin or carbamazepine alone or with a combination with one other drug." | 3.67 | Anticonvulsant drug therapy in human pregnancy: effects on serum concentrations of vitamin D metabolites in maternal and cord blood. ( Aarskog, D; Aksnes, L; Markestad, T; Strandjord, RE; Ulstein, M, 1984) |
| "Neural tube, craniofacial, and other congenital abnormalities have been described in infants born to mothers with epilepsy who were treated with valproic acid (VPA) during pregnancy." | 3.67 | Congenital abnormalities in two sibs exposed to valproic acid in utero. ( Anderson, L; Chitayat, D; Farrell, K; Hall, JG, 1988) |
| " The mother had received carbamazepine therapy for epilepsy." | 3.67 | Persistent right umbilical vein--case report and review of literature. ( Bell, AD; Gerlis, LM; Variend, S, 1986) |
| "An epileptic patient whose seizures were controlled with carbamazepine and primidone was followed throughout pregnancy and lactation." | 3.66 | Carbamazepine levels in pregnancy and lactation. ( Blake, DA; Freeman, JM; Luff, RD; Niebyl, JR, 1979) |
| "The pharmacokinetics of carbamazepine were studied during pregnancy and early childhood by investigating the extent of its placental penetration and its distribution in the foetal and neonatal tissues at autopsy." | 3.65 | Carbamazepine: placental transport, tissue concentrations in foetus and newborn, and level in milk. ( Erkkola, R; Kanto, J; Pynnönen, S; Sillanpää, M, 1977) |
| "Levetiracetam has been widely used as a treatment option for different types of epilepsy in both adults and children." | 2.72 | Population Pharmacokinetics of Levetiracetam: A Systematic Review. ( Jiao, Z; Li, ZR; Wang, CY; Zhu, X, 2021) |
| "Pregnancy was thus associated with increased microsomal oxidations of phenytoin and carbamazepine, without proportionate increases in the subsequent hydrolysis of carbamazepine-10,11-epoxide and in the O-glucuronidations of the earlier stage metabolites." | 2.68 | Effects of pregnancy on various pathways of human antiepileptic drug metabolism. ( Bernus, I; Dickinson, RG; Eadie, MJ; Hooper, WD, 1997) |
| "Oxcarbazepine is a second-generation antiepileptic drug that is used to treat partial seizures." | 2.55 | In Utero Oxcarbazepine Exposure and Neonatal Abstinence Syndrome: Case Report and Brief Review of the Literature. ( Chen, CY; Cui, YM; Feng, Q; Li, X; Ma, LY; Wu, PH; Zhou, Y, 2017) |
| "Lamotrigine was preferred in patients with co-morbid depression." | 2.55 | Epilepsy treatment in adults and adolescents: Expert opinion, 2016. ( Chimato, N; Frank, RD; Karceski, SC; Shih, JJ; Vargas, E; Whitlock, JB, 2017) |
| "Pharmacotherapy for mood disorders during pregnancy is often complicated by pregnancy-related pharmacokinetic changes and the need for dose adjustments." | 2.50 | Pharmacotherapy for mood disorders in pregnancy: a review of pharmacokinetic changes and clinical recommendations for therapeutic drug monitoring. ( Byatt, N; Deligiannidis, KM; Freeman, MP, 2014) |
| "Seizures and intracranial hemorrhage are possible medical diseases that any obstetrician may encounter." | 2.49 | Seizures and intracranial hemorrhage. ( Alexander, JM; Wilson, KL, 2013) |
| "Phenobarbital was associated with a higher rate of drug withdrawal although there was no evidence to suggest that phenobarbital caused more adverse events compared to carbamazepine, valproic acid or phenytoin." | 2.47 | Side effects of phenobarbital in epilepsy: a systematic review. ( Li, YP; Zeng, LN; Zhang, LL, 2011) |
| "Neural tube defects (NTDs), including spina bifida and anencephaly, are common congenital malformations that occur when the neural tube fails to achieve proper closure during early embryogenesis." | 2.42 | Pathobiology and genetics of neural tube defects. ( Finnell, RH; Gould, A; Spiegelstein, O, 2003) |
| " Rates of metabolism in children may be much faster than in nonelderly adults, requiring dosing adjustments to ensure enough medication is used to control seizures." | 2.41 | Treatment of epilepsy in 3 specialized populations. ( Leppik, IE, 2001) |
| "We also present an overview of the psychiatric disorders in which carbamazepine has been found, or suggested, to be efficacious." | 2.39 | Carbamazepine clinical pharmacology: a review. ( Albani, F; Baruzzi, A; Riva, R, 1995) |
| "Restless legs syndrome is a common complaint in pregnancy affecting up to one in every three women." | 2.38 | Restless legs syndrome in pregnancy. Case reports. ( McParland, P; Pearce, JM, 1990) |
| "Anticonvulsant therapy was among the first areas to benefit from clinical pharmacokinetic studies." | 2.35 | Clinical pharmacokinetics of anticonvulsants. ( Dam, M; Hvidberg, EF, 1976) |
| "Carbamazepine was detectable (≥1." | 1.56 | Involuntary human exposure to carbamazepine: A cross-sectional study of correlates across the lifespan and dietary spectrum. ( Chefetz, B; Golan, N; Goldsmith, R; Kalo, D; Kirshenbaum, N; Manor, O; Mordehay, V; Paltiel, O; Schapira, M, 2020) |
| "To study the risk of intellectual disability and delayed development in childhood milestones among children of women who used valproate or other AEDs during pregnancy." | 1.56 | Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Intellectual Disability and Delayed Childhood Milestones. ( Christensen, J; Daugaard, CA; Dreier, JW; Pedersen, L; Sun, Y, 2020) |
| "Children with Congenital Zika Syndrome and microcephaly are at high risk for epilepsy; however, the risk is unclear in normocephalic children with prenatal Zika virus (ZIKV) exposure [Exposed Children (EC)]." | 1.56 | Epilepsy surveillance in normocephalic children with and without prenatal Zika virus exposure. ( Abdel Baki, S; Blackmon, K; Burgen, KS; Chari, G; Cudjoe, N; Dlugos, D; Donald, T; Evans, R; Grossi-Soyster, EN; Jayatilake, P; Krystosik, AR; LaBeaud, AD; Landon, B; Macpherson, C; Noël, T; Oyegunle, V; Patel, AA; Pedraza, O; Thesen, T; Waechter, R, 2020) |
| "Usually, no adverse effects are observed in breastfed infants whose mothers are treated with the anti-epileptic carbamazepine." | 1.48 | Maternal Carbamazepine Therapy and Unusual Adverse Effects in a Breastfed Infant. ( Antonucci, R; Cherchi, C; Cuzzolin, L; Locci, C; Manconi, A; Oggiano, AM, 2018) |
| "Evidence for the comparative teratogenic risk of antiepileptic drugs is insufficient, particularly in relation to the dosage used." | 1.48 | Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry. ( Battino, D; Bonizzoni, E; Craig, J; Lindhout, D; Perucca, E; Sabers, A; Thomas, SV; Tomson, T; Vajda, F, 2018) |
| "LEV provides similar seizure control to that of the older AEDs, and it is more effective and better than LTG." | 1.48 | Comparative study of antiepileptic drug use during pregnancy over a period of 12 years in Spain. Efficacy of the newer antiepileptic drugs lamotrigine, levetiracetam, and oxcarbazepine. ( Escartin Siquier, A; Forcadas Berdusan, M; Martin Moro, M; Martinez Ferri, M; Peña Mayor, P; Perez López-Fraile, I, 2018) |
| "Psychoactive pharmaceuticals have been found as teratogens at clinical dosage during pregnancy." | 1.43 | Maternal exposure to carbamazepine at environmental concentrations can cross intestinal and placental barriers. ( Aho, K; Bearden, S; Finney, B; Huber, DP; Kaushik, G; Thomas, MA; Zarbalis, KS, 2016) |
| "Carbamazepine and water were given by gastric gavage throughout gestational period." | 1.42 | Teratogenic effect of Carbamazepine use during pregnancy in the mice. ( El-Kenawy, Ael-M; Elshama, SS; Osman, HE, 2015) |
| "Carbamazepine (CBZ) is an anti-epileptic drug that acts on Leydig cells, affecting steroidogenesis and causes fetal malformation." | 1.40 | Carbamazepine-exposure during gestation and lactation affects pubertal onset and spermatic parameters in male pubertal offspring. ( Andretta, RR; de Oliva, SU; Miraglia, SM; Okada, FK; Paccola, CC; Stumpp, T, 2014) |
| "We present a female with seizures one month after delivery who had borderline elevated liver enzymes prior to the initiation of OXC treatment." | 1.39 | Acute oxcarbazepine-induced hepatotoxicity in a patient susceptible to developing drug-induced liver injury. ( Bielen, A; Bielen, I; Marusić, M; Planjar-Prvan, M; Sruk, A, 2013) |
| " The mean dosage of AED for valproate was 498 mg/day and carbamazepine was 555 mg/day." | 1.39 | Malformation in index pregnancy in women with epilepsy is not followed by recurrence in subsequent pregnancy. ( Begum, S; Sarma, SP; Thomas, SV, 2013) |
| "Carbamazepine is an antiepileptic drug used widely for the treatment of epileptic seizures and neuropathic pain." | 1.36 | Teratogenic effects of carbamazepine on embryonic eye development in pregnant mice. ( Afshar, M; Houshang Mohammadpour, A; Jafar Golalipour, M; Majid Jalalian, S; Moallem, SA; Shiravi, A, 2010) |
| " In case of breakthrough seizures or increased seizure frequency, dosage adjustment of both drugs may be required." | 1.36 | Drug monitoring of lamotrigine and oxcarbazepine combination during pregnancy. ( de Haan, GJ; Edelbroek, P; Lindhout, D; Sander, JW; Wegner, I, 2010) |
| "Lamotrigine (LTG) has been used in epilepsia patients for treatment of partial seizures." | 1.35 | Unilateral radius aplasia due to lamotrigine and oxcarbazepine use in pregnancy. ( Cetinkaya, M; Köksal, N; Ozkan, H, 2008) |
| " Carbamazepine (CBZ) and phenobarbital (PHB) during pregnancy should be used at the lowest dosage compatible with maternal disease." | 1.34 | Unilateral multicystic dysplastic kidney in infants exposed to antiepileptic drugs during pregnancy. ( Carta, M; Cimador, M; Corsello, G; De Grazia, E; Di Pace, MR; Giuffrè, M; Sergio, M, 2007) |
| " The number or dosage of AEDs were more often increased in pregnancies with seizures (OR: 3." | 1.33 | Seizure control and treatment in pregnancy: observations from the EURAP epilepsy pregnancy registry. ( , 2006) |
| "Women with epilepsy have a higher risk of having dysmorphic child." | 1.33 | A case of fetal anticonvulsant syndrome with severe bilateral upper limb defect. ( Batukan, C; Ceylaner, G; Ceylaner, S; Guven, MA; Uzel, M, 2006) |
| "The incidence of birth defects in relation to specific AEDs was: valproate (16." | 1.32 | The Australian registry of anti-epileptic drugs in pregnancy: experience after 30 months. ( Graham, J; Hitchcock, A; Lander, C; O'Brien, TJ; Vajda, FJ, 2003) |
| " However, there is no information available on the number of therapeutic abortions, or the different types of epilepsy or drug dosage in the two treatment groups." | 1.32 | Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study. ( Källén, B; Wide, K; Winbladh, B, 2004) |
| "Oxcarbazepine (OXC) is a new antiepileptic drug derived from carbamazepine (CBZ)." | 1.31 | [Oxcarbazepine]. ( Arroyo, S, 2001) |
| " During this pregnancy the patient took a reduced dosage of carbamazepine." | 1.29 | Fetal malformations in an epileptic pregnant woman treated with carbamazepine. ( Caradonna, F; Caruso, G; Ceci, O; Clemente, R; Ferreri, R; Loizzi, P, 1996) |
| " Phenobarbital cotreatment (45 mg/kg/day) with OXC (1100 mg/kg/day) did not lead to changes in the incidence of malformation when compared with OXC (1100 mg/kg/day) dosed alone." | 1.29 | Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse. ( Amore, BM; Bennett, GD; Finnell, RH; Kalhorn, TF; Nelson, SD; Skiles, GL; Slattery, JT; Wlodarczyk, B, 1996) |
| "Carbamazepine was the antiepileptic drug prescribed most frequently followed by valproic acid." | 1.28 | [The course of pregnancy and teratogenicity of antiepileptic agents in 66 patients with epilepsy]. ( Bülau, P; Fröscher, W; Herrmann, R; Hildenbrand, G; Niesen, M; Penin, H, 1991) |
| " Pharmacokinetic interactions between antiepileptic drugs may lead to considerable fluctuation in plasma drug concentration, and monotherapy is often preferable." | 1.27 | Pharmacokinetics of antiepileptic drugs. ( Neuvonen, PJ; Tokola, RA, 1983) |
| "Only when the epilepsy is uncontrolled despite high plasma concentrations which cannot be raised because of side effects, a second drug should be given." | 1.27 | [Pharmacotherapy of epilepsy--current problems and controversies]. ( Schmidt, D, 1983) |
| "Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment." | 1.27 | Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983) |
| "The objective of this investigation was to study the teratogenic effects of dosage levels and time of administration of three anticonvulsant drugs (carbamazepine [CMZ], sodium valproate [NaV], and diphenylhydantoin [DPH]) on craniofacial development in the CD-1 mouse fetus." | 1.27 | Teratogenic effects of dosage levels and time of administration of carbamazepine, sodium valproate, and diphenylhydantoin on craniofacial development in the CD-1 mouse fetus. ( Eluma, FO; Hayes, TG; Paulson, RB; Sucheston, ME, 1984) |
| "The effects of pregnancy on seizure excitability as well as antiepileptic drug disposition and efficacy were studied in the mouse during late gestation." | 1.27 | Effects of pregnancy on seizure threshold and the disposition and efficacy of antiepileptic drugs in the mouse. ( Kuhnz, W; Löscher, W; Nau, H, 1985) |
| " The mechanisms responsible for these effects have not been elucidated and possibly include decreased bioavailability or compliance, increased metabolic clearance, or decreased plasma protein binding." | 1.27 | Effects of pregnancy on antiepileptic drug utilization. ( Levy, RH; Yerby, MS, 1985) |
| "The incidence of malformations in fetal mice exposed to phenytoin depends on drug dosage and the strain of mice." | 1.26 | Teratogenic effects of anticonvulsants. ( Paulson, GW; Paulson, RB, 1981) |
| "Only 21% of those with myoclonic astatic epilepsy have become free from seizures." | 1.26 | Sodium valproate: monotherapy and polytherapy. ( Covanis, A; Gupta, AK; Jeavons, PM, 1982) |
| " Monitoring plasma concentrations may lead to adaptations of the choice of the drug and of the dosage regimen." | 1.26 | Kinetics of drug interactions in the treatment of epilepsy. ( Guelen, P; Knop, H; Schobten, F; van der Kleijn, E; Vree, T; Westenberg, H, 1978) |
| " In all cases, data on plasma levels were subjected to pharmacokinetic analyses." | 1.26 | Carbamazepine pharmacokinetics in young, adult and pregnant rats. Relation to pharmacological effects. ( Assael, BM; Bossi, L; Garattini, S; Gerna, M; Gomeni, R; Morselli, PL, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 101 (26.86) | 18.7374 |
| 1990's | 75 (19.95) | 18.2507 |
| 2000's | 86 (22.87) | 29.6817 |
| 2010's | 87 (23.14) | 24.3611 |
| 2020's | 27 (7.18) | 2.80 |
| Authors | Studies |
|---|---|
| Dickmann, LJ | 1 |
| Isoherranen, N | 1 |
| Mari, L | 1 |
| Placidi, F | 1 |
| Romigi, A | 1 |
| Tombini, M | 1 |
| Del Bianco, C | 1 |
| Ulivi, M | 1 |
| Liguori, C | 1 |
| Manfredi, N | 1 |
| Castelli, A | 1 |
| Mercuri, NB | 1 |
| Izzi, F | 1 |
| Adams, J | 2 |
| Janulewicz, PA | 1 |
| Macklin, EA | 1 |
| Dhillon, R | 1 |
| Phillips, C | 2 |
| Schomer, DL | 1 |
| Tosches, WA | 1 |
| Carlson, JM | 1 |
| Holmes, LB | 5 |
| Pennell, PB | 7 |
| Karanam, A | 1 |
| Meador, KJ | 9 |
| Gerard, E | 1 |
| Kalayjian, L | 1 |
| Penovich, P | 1 |
| Matthews, A | 1 |
| McElrath, TM | 1 |
| Birnbaum, AK | 1 |
| Kacirova, I | 2 |
| Grundmann, M | 2 |
| Brozmanova, H | 2 |
| Bjørk, MH | 6 |
| Zoega, H | 5 |
| Leinonen, MK | 5 |
| Cohen, JM | 5 |
| Dreier, JW | 3 |
| Furu, K | 5 |
| Gilhus, NE | 2 |
| Gissler, M | 5 |
| Hálfdánarson, Ó | 1 |
| Igland, J | 2 |
| Sun, Y | 3 |
| Tomson, T | 16 |
| Alvestad, S | 5 |
| Christensen, J | 5 |
| Ren, T | 1 |
| Lee, PMY | 1 |
| Li, F | 1 |
| Li, J | 2 |
| Cesta, CE | 3 |
| Nørgaard, M | 3 |
| Einarsdóttir, K | 3 |
| Engeland, A | 3 |
| Karlstad, Ø | 3 |
| Klungsøyr, K | 3 |
| Odsbu, I | 3 |
| Reutfors, J | 3 |
| Selmer, RM | 3 |
| Ulrichsen, SP | 3 |
| Vajda, F | 5 |
| O'Brien, T | 1 |
| Graham, J | 4 |
| Hitchcock, A | 2 |
| Perucca, P | 1 |
| Lander, C | 2 |
| Eadie, M | 1 |
| Pekoz, MT | 1 |
| Aslan-Kara, K | 1 |
| Tekin, B | 1 |
| Gurses, C | 1 |
| Yeni, SN | 1 |
| Bozdemir, H | 1 |
| Keskin-Guler, S | 1 |
| Ataklı, D | 2 |
| Gul, G | 1 |
| Eren, F | 1 |
| Sarı, H | 1 |
| Gul, ZB | 1 |
| Ceyhan-Dirican, A | 1 |
| Genc, F | 1 |
| Bicer-Gomceli, Y | 1 |
| Ozkara, C | 2 |
| Delil, S | 1 |
| Atalar, AC | 1 |
| Bebek, N | 1 |
| Baykan, B | 1 |
| Bora, İ | 1 |
| Bican-Demir, A | 1 |
| Mısırlı, CH | 1 |
| Tutkavul, K | 1 |
| Velioglu, SK | 1 |
| Ilhan-Algin, D | 1 |
| Erdinc, O | 1 |
| Saygi, S | 1 |
| Tezer-Fılık, I | 1 |
| Apaydın-Dogan, E | 1 |
| Akyol, A | 1 |
| Kamisli, O | 1 |
| Yalcın, AD | 1 |
| Cakmak, G | 1 |
| Ersoy, A | 1 |
| Ustun-Ozek, S | 1 |
| Halac, G | 1 |
| Kutlu, G | 1 |
| Tantik-Pak, A | 1 |
| Yücel, SP | 1 |
| Du, Y | 1 |
| Xu, Q | 1 |
| Lin, J | 1 |
| Gong, J | 1 |
| Xia, N | 1 |
| Zhu, Z | 1 |
| Wang, X | 1 |
| Zheng, R | 1 |
| Xu, H | 1 |
| Kardoost, M | 1 |
| Hajizadeh-Saffar, E | 1 |
| Ghorbanian, MT | 1 |
| Ghezelayagh, Z | 1 |
| Pooshang Bagheri, K | 1 |
| Behdani, M | 1 |
| Habibi-Anbouhi, M | 1 |
| Husebye, ESN | 1 |
| Spigset, O | 1 |
| Daltveit, AK | 1 |
| Keni, RR | 1 |
| Jose, M | 1 |
| A S, R | 1 |
| Baishya, J | 1 |
| Sankara Sarma, P | 1 |
| Thomas, SV | 3 |
| Söderberg Löfdal, K | 1 |
| Huber-Mollema, Y | 2 |
| van Iterson, L | 1 |
| Oort, FJ | 2 |
| Lindhout, D | 12 |
| Rodenburg, R | 2 |
| Clark, CT | 1 |
| de Oliva, SU | 2 |
| Engelbrecht, RM | 1 |
| Miraglia, SM | 3 |
| Schapira, M | 1 |
| Manor, O | 1 |
| Golan, N | 1 |
| Kalo, D | 1 |
| Mordehay, V | 1 |
| Kirshenbaum, N | 1 |
| Goldsmith, R | 1 |
| Chefetz, B | 1 |
| Paltiel, O | 1 |
| Wiggs, KK | 1 |
| Rickert, ME | 1 |
| Sujan, AC | 1 |
| Quinn, PD | 1 |
| Larsson, H | 1 |
| Lichtenstein, P | 1 |
| Oberg, AS | 1 |
| D'Onofrio, BM | 1 |
| Daugaard, CA | 1 |
| Pedersen, L | 1 |
| Blackmon, K | 1 |
| Waechter, R | 1 |
| Landon, B | 1 |
| Noël, T | 1 |
| Macpherson, C | 1 |
| Donald, T | 1 |
| Cudjoe, N | 1 |
| Evans, R | 1 |
| Burgen, KS | 1 |
| Jayatilake, P | 1 |
| Oyegunle, V | 1 |
| Pedraza, O | 1 |
| Abdel Baki, S | 1 |
| Thesen, T | 1 |
| Dlugos, D | 1 |
| Chari, G | 1 |
| Patel, AA | 1 |
| Grossi-Soyster, EN | 1 |
| Krystosik, AR | 1 |
| LaBeaud, AD | 1 |
| Vajda, FJE | 3 |
| O'Brien, TJ | 5 |
| Graham, JE | 1 |
| Hitchcock, AA | 2 |
| Mitchell, J | 1 |
| Horgan, D | 1 |
| Lander, CM | 3 |
| Eadie, MJ | 8 |
| Oliva, SU | 1 |
| Andretta, RR | 2 |
| Simas, JN | 1 |
| Tesser, RB | 1 |
| Paccola, CC | 2 |
| Li, ZR | 1 |
| Wang, CY | 1 |
| Zhu, X | 1 |
| Jiao, Z | 1 |
| Kaplan, YC | 1 |
| Demir, O | 1 |
| Kakumoto, M | 1 |
| Shimokawa, K | 1 |
| Ueshima, S | 1 |
| Hira, D | 1 |
| Okano, T | 1 |
| Pariente, G | 1 |
| Leibson, T | 1 |
| Shulman, T | 1 |
| Adams-Webber, T | 1 |
| Barzilay, E | 1 |
| Nulman, I | 4 |
| Chen, CY | 1 |
| Li, X | 1 |
| Ma, LY | 1 |
| Wu, PH | 1 |
| Zhou, Y | 2 |
| Feng, Q | 1 |
| Cui, YM | 1 |
| Veroniki, AA | 1 |
| Rios, P | 1 |
| Cogo, E | 1 |
| Straus, SE | 1 |
| Finkelstein, Y | 1 |
| Kealey, R | 1 |
| Reynen, E | 1 |
| Soobiah, C | 1 |
| Thavorn, K | 1 |
| Hutton, B | 1 |
| Hemmelgarn, BR | 1 |
| Yazdi, F | 1 |
| D'Souza, J | 2 |
| MacDonald, H | 1 |
| Tricco, AC | 1 |
| Patel, N | 1 |
| Viguera, AC | 1 |
| Baldessarini, RJ | 1 |
| Graham, RK | 1 |
| Tavella, G | 1 |
| Parker, GB | 1 |
| Antonucci, R | 1 |
| Cuzzolin, L | 1 |
| Manconi, A | 1 |
| Cherchi, C | 1 |
| Oggiano, AM | 1 |
| Locci, C | 1 |
| Battino, D | 5 |
| Bonizzoni, E | 3 |
| Craig, J | 4 |
| Perucca, E | 6 |
| Sabers, A | 6 |
| Thangaratinam, S | 1 |
| Marlin, N | 1 |
| Newton, S | 1 |
| Weckesser, A | 1 |
| Bagary, M | 1 |
| Greenhill, L | 1 |
| Rikunenko, R | 1 |
| D'Amico, M | 1 |
| Rogozińska, E | 1 |
| Kelso, A | 1 |
| Hard, K | 1 |
| Coleman, J | 1 |
| Moss, N | 1 |
| Roberts, T | 1 |
| Middleton, L | 1 |
| Dodds, J | 1 |
| Pullen, A | 1 |
| Eldridge, S | 1 |
| Pirie, A | 1 |
| Denny, E | 1 |
| McCorry, D | 1 |
| Khan, KS | 1 |
| Galappatthy, P | 1 |
| Liyanage, CK | 1 |
| Lucas, MN | 1 |
| Jayasekara, DTLM | 1 |
| Abhayaratna, SA | 1 |
| Weeraratne, C | 1 |
| De Abrew, K | 1 |
| Gunaratne, PS | 1 |
| Gamage, R | 1 |
| Wijeyaratne, CN | 1 |
| Barton, S | 1 |
| Nadebaum, C | 1 |
| Anderson, VA | 1 |
| Reutens, DC | 1 |
| Wood, AG | 1 |
| Cohen, MJ | 2 |
| May, R | 1 |
| Loblein, H | 1 |
| Conrad, T | 1 |
| Baker, GA | 7 |
| Bromley, RL | 3 |
| Clayton-Smith, J | 7 |
| Kalayjian, LA | 5 |
| Kanner, A | 3 |
| Liporace, JD | 4 |
| Privitera, M | 3 |
| Loring, DW | 6 |
| Richards, N | 1 |
| Reith, D | 1 |
| Stitely, M | 1 |
| Smith, A | 1 |
| Yang, F | 1 |
| Yuan, W | 1 |
| Liang, H | 1 |
| Song, X | 1 |
| Yu, Y | 1 |
| Gelaye, B | 1 |
| Miao, M | 1 |
| Johnson, KD | 1 |
| Miller, LN | 1 |
| Pouliot, JD | 1 |
| Martin, PR | 1 |
| Giménez, A | 1 |
| Pacchiarotti, I | 1 |
| Gil, J | 1 |
| Murru, A | 1 |
| Gomes, SP | 1 |
| Pinzón, JE | 1 |
| Anmella, G | 1 |
| Gómez-Ramiro, M | 1 |
| Verdolini, N | 1 |
| Valentí, M | 1 |
| Goikolea, JM | 1 |
| Vieta, E | 1 |
| Wilson, KL | 1 |
| Alexander, JM | 1 |
| Rolnitsky, A | 1 |
| Merlob, P | 2 |
| Klinger, G | 1 |
| Planjar-Prvan, M | 1 |
| Bielen, A | 1 |
| Sruk, A | 1 |
| Marusić, M | 1 |
| Bielen, I | 1 |
| Tica, OS | 1 |
| Tica, AA | 1 |
| Brailoiu, CG | 1 |
| Cernea, N | 1 |
| Tica, VI | 1 |
| Eikmeier, G | 1 |
| Forquignon, I | 1 |
| Honig, H | 1 |
| Okada, FK | 1 |
| Stumpp, T | 1 |
| Begum, S | 1 |
| Sarma, SP | 1 |
| Åberg, E | 1 |
| Holst, S | 1 |
| Neagu, A | 1 |
| Ögren, SO | 1 |
| Lavebratt, C | 1 |
| Lee, SH | 1 |
| Kang, JW | 1 |
| Lin, T | 1 |
| Lee, JE | 1 |
| Jin, DI | 1 |
| Campbell, E | 1 |
| Kennedy, F | 1 |
| Russell, A | 1 |
| Smithson, WH | 1 |
| Parsons, L | 1 |
| Morrison, PJ | 1 |
| Liggan, B | 1 |
| Irwin, B | 1 |
| Delanty, N | 1 |
| Hunt, SJ | 1 |
| Morrow, J | 2 |
| Deligiannidis, KM | 1 |
| Byatt, N | 1 |
| Freeman, MP | 1 |
| Johnson, EL | 1 |
| Stowe, ZN | 2 |
| Ritchie, JC | 1 |
| Newport, DJ | 2 |
| Newman, ML | 1 |
| Knight, B | 1 |
| Baranyai, D | 1 |
| Muro, E | 1 |
| Gödtel-Armbrust, U | 1 |
| Schirmer, MA | 1 |
| Kisanga, E | 1 |
| Diczfalusy, U | 1 |
| Fillekes, Q | 2 |
| Schuurman, R | 2 |
| Burger, D | 1 |
| Wojnowski, L | 1 |
| Verrotti, A | 1 |
| Scaparrotta, A | 1 |
| Cofini, M | 1 |
| Chiarelli, F | 1 |
| Tiboni, GM | 1 |
| Vereczkey, A | 1 |
| Gerencsér, B | 1 |
| Czeizel, AE | 2 |
| Szabó, I | 1 |
| Bromley, R | 2 |
| Weston, J | 1 |
| Adab, N | 2 |
| Greenhalgh, J | 1 |
| Sanniti, A | 1 |
| McKay, AJ | 1 |
| Tudur Smith, C | 1 |
| Marson, AG | 1 |
| Briggs, M | 2 |
| Cheyne, CP | 1 |
| García-Fiñana, M | 2 |
| Gummery, A | 1 |
| Kneen, R | 2 |
| Mawer, G | 3 |
| Shallcross, R | 2 |
| Klein, P | 1 |
| Elshama, SS | 1 |
| Osman, HE | 1 |
| El-Kenawy, Ael-M | 1 |
| Lopalco, A | 1 |
| Ali, H | 1 |
| Denora, N | 1 |
| Rytting, E | 1 |
| Pelizzo, G | 1 |
| Calcaterra, V | 1 |
| Mannarino, S | 1 |
| Moramarco, LP | 1 |
| Leati, G | 1 |
| Quaretti, P | 1 |
| Homberg, V | 1 |
| Lavi-Blau, T | 1 |
| Ekstein, D | 1 |
| Neufeld, MY | 1 |
| Eyal, S | 1 |
| Vanya, M | 1 |
| Devosa, I | 1 |
| Szok, D | 1 |
| Bártfai, G | 1 |
| Kaushik, G | 1 |
| Huber, DP | 1 |
| Aho, K | 1 |
| Finney, B | 1 |
| Bearden, S | 1 |
| Zarbalis, KS | 1 |
| Thomas, MA | 1 |
| Hirashima, R | 1 |
| Michimae, H | 1 |
| Takemoto, H | 1 |
| Sasaki, A | 1 |
| Kobayashi, Y | 1 |
| Itoh, T | 1 |
| Tukey, RH | 1 |
| Fujiwara, R | 1 |
| Martinez Ferri, M | 1 |
| Peña Mayor, P | 1 |
| Perez López-Fraile, I | 1 |
| Escartin Siquier, A | 1 |
| Martin Moro, M | 1 |
| Forcadas Berdusan, M | 1 |
| Würtz, AM | 1 |
| Rytter, D | 1 |
| Vestergaard, CH | 1 |
| Vestergaard, M | 1 |
| Bech, BH | 1 |
| Shih, JJ | 1 |
| Whitlock, JB | 1 |
| Chimato, N | 1 |
| Vargas, E | 1 |
| Karceski, SC | 1 |
| Frank, RD | 1 |
| Ahmed, RG | 1 |
| El-Gareib, AW | 1 |
| Lazorwitz, A | 1 |
| Davis, A | 1 |
| Swartz, M | 1 |
| Guiahi, M | 1 |
| Pearlstein, T | 1 |
| Harden, CL | 1 |
| Sethi, NK | 1 |
| Cetinkaya, M | 1 |
| Ozkan, H | 1 |
| Köksal, N | 1 |
| Aksamija, A | 1 |
| Habek, D | 1 |
| Stanojević, M | 1 |
| Ujević, B | 1 |
| Petrenaite, V | 1 |
| Hansen-Schwartz, J | 1 |
| Ackers, R | 1 |
| Besag, FM | 1 |
| Wade, A | 1 |
| Murray, ML | 1 |
| Wong, IC | 1 |
| Browning, N | 2 |
| Combs-Cantrell, DT | 2 |
| Cohen, M | 2 |
| Bozhinov, P | 1 |
| Bozhinova, C | 1 |
| Markova, C | 1 |
| Cansu, A | 2 |
| Erdogan, D | 2 |
| Serdaroglu, A | 1 |
| Take, G | 1 |
| Coskun, ZK | 2 |
| Gurgen, SG | 2 |
| Somerville, ER | 1 |
| Cook, MJ | 1 |
| Asnis, D | 1 |
| Kazakov, J | 1 |
| Toronjadze, T | 1 |
| Bern, C | 1 |
| Garcia, HH | 1 |
| McAuliffe, I | 1 |
| Bishop, H | 1 |
| Lee, L | 1 |
| Grossmann, R | 1 |
| Garcia, MA | 1 |
| Di John, D | 1 |
| McVearry, KM | 1 |
| Gaillard, WD | 1 |
| VanMeter, J | 1 |
| Afshar, M | 1 |
| Moallem, SA | 1 |
| Houshang Mohammadpour, A | 1 |
| Shiravi, A | 1 |
| Majid Jalalian, S | 1 |
| Jafar Golalipour, M | 1 |
| Nassef, M | 1 |
| Kim, SG | 1 |
| Seki, M | 1 |
| Kang, IJ | 1 |
| Hano, T | 1 |
| Shimasaki, Y | 1 |
| Oshima, Y | 1 |
| Zhao, M | 1 |
| Yang, L | 1 |
| Wei, Y | 1 |
| Xiong, X | 1 |
| Zhai, SD | 1 |
| Galbally, M | 1 |
| Roberts, M | 1 |
| Buist, A | 1 |
| Jentink, J | 2 |
| Dolk, H | 1 |
| Loane, MA | 1 |
| Morris, JK | 1 |
| Wellesley, D | 1 |
| Garne, E | 1 |
| de Jong-van den Berg, L | 1 |
| Chambers, CD | 2 |
| Wegner, I | 1 |
| Edelbroek, P | 1 |
| de Haan, GJ | 1 |
| Sander, JW | 2 |
| Iniesta, I | 1 |
| Cummings, C | 1 |
| Stewart, M | 1 |
| Stevenson, M | 1 |
| Nelson, J | 1 |
| Mittendorf, R | 1 |
| Shen, A | 1 |
| Smith, CR | 1 |
| Hernandez-Diaz, S | 1 |
| Kulaga, S | 1 |
| Sheehy, O | 1 |
| Zargarzadeh, AH | 1 |
| Moussally, K | 1 |
| Bérard, A | 1 |
| Gilboa, SM | 2 |
| Broussard, CS | 1 |
| Devine, OJ | 1 |
| Duwe, KN | 1 |
| Flak, AL | 1 |
| Boulet, SL | 1 |
| Moore, CA | 1 |
| Werler, MM | 2 |
| Honein, MA | 1 |
| Zhang, LL | 1 |
| Zeng, LN | 1 |
| Li, YP | 1 |
| Ahrens, KA | 1 |
| Bosco, JL | 1 |
| Mitchell, AA | 1 |
| Anderka, MT | 1 |
| Muro, EP | 1 |
| Kisanga, ER | 1 |
| L'homme, R | 1 |
| Aitken, SC | 1 |
| Mariki, G | 1 |
| Van der Ven, AJ | 1 |
| Dolmans, W | 1 |
| Walker, AS | 1 |
| Gibb, DM | 1 |
| Burger, DM | 1 |
| Staikou, C | 1 |
| Mani, A | 1 |
| Petropoulos, G | 1 |
| Blumkin, L | 1 |
| Suls, A | 1 |
| Deconinck, T | 1 |
| De Jonghe, P | 1 |
| Linder, I | 1 |
| Kivity, S | 1 |
| Dabby, R | 1 |
| Leshinsky-Silver, E | 1 |
| Lev, D | 1 |
| Lerman-Sagie, T | 1 |
| Azak, A | 1 |
| Koçak, G | 1 |
| Huddam, B | 1 |
| Duranay, M | 1 |
| Matlow, J | 1 |
| Koren, G | 6 |
| Uludag, S | 1 |
| Aydin, Y | 1 |
| Yilmaz, O | 1 |
| Aksoy, F | 1 |
| Bakkaloglu, D | 1 |
| Sen, C | 1 |
| Smith, AK | 1 |
| Conneely, KN | 1 |
| Kilaru, V | 1 |
| Schroeder, JW | 1 |
| Knight, BT | 1 |
| Cubells, JC | 1 |
| Brennan, PA | 1 |
| Boersma, C | 1 |
| de Jong-van den Berg, LT | 1 |
| Postma, MJ | 1 |
| Akar, M | 1 |
| Dilli, D | 1 |
| Yilmaz, Y | 1 |
| Erdeve, O | 1 |
| Oguz, S | 1 |
| Uras, N | 1 |
| Dilmen, U | 1 |
| Dursun, A | 1 |
| Karadağ, N | 1 |
| Karagöl, B | 1 |
| Kundak, AA | 1 |
| Zenciroğlu, A | 1 |
| Okumuş, N | 1 |
| Ceylaner, S | 2 |
| Sanaei-Zadeh, H | 1 |
| Bravo, A | 1 |
| Hernandez, D | 1 |
| Martinez-Villarreal, L | 1 |
| Elizondo, G | 1 |
| Esmer, C | 1 |
| Turek, T | 1 |
| Wigton, A | 1 |
| Mawer, GE | 1 |
| Cheyne, C | 1 |
| Lucas, SB | 1 |
| Poblano, A | 1 |
| Belmont, A | 1 |
| Sosa, J | 1 |
| Ibarra, J | 1 |
| Rosas, Y | 1 |
| López, V | 1 |
| Garza, S | 1 |
| Kroes, HY | 1 |
| Reefhuis, J | 1 |
| Cornel, MC | 2 |
| Smyth, MD | 1 |
| Barbaro, NM | 1 |
| Baraban, SC | 1 |
| Wester, U | 1 |
| Brandberg, G | 1 |
| Larsson, M | 1 |
| Lönnerholm, T | 1 |
| Annerén, G | 1 |
| Kaaja, E | 2 |
| Kaaja, R | 1 |
| Hiilesmaa, V | 2 |
| Yerby, MS | 9 |
| Finnell, RH | 4 |
| Gould, A | 1 |
| Spiegelstein, O | 1 |
| Vajda, FJ | 1 |
| Deering, SH | 1 |
| Thompson, K | 1 |
| Taylor, J | 1 |
| Hueppchen, N | 1 |
| Miller, M | 1 |
| Zaninelli, R | 1 |
| Gaily, E | 1 |
| Kantola-Sorsa, E | 1 |
| Isoaho, M | 1 |
| Matila, R | 1 |
| Kotila, M | 1 |
| Nylund, T | 1 |
| Bardy, A | 1 |
| Granström, ML | 4 |
| Meischenguiser, R | 2 |
| D'Giano, CH | 2 |
| Ferraro, SM | 2 |
| Christensen, HD | 2 |
| Rayburn, WF | 2 |
| Parker, KM | 2 |
| Gonzalez, CL | 2 |
| Gold, KP | 1 |
| Wide, K | 2 |
| Winbladh, B | 2 |
| Källén, B | 3 |
| Yonkers, KA | 1 |
| Wisner, KL | 2 |
| Stowe, Z | 1 |
| Leibenluft, E | 1 |
| Cohen, L | 1 |
| Miller, L | 1 |
| Manber, R | 1 |
| Viguera, A | 1 |
| Suppes, T | 1 |
| Altshuler, L | 1 |
| Shorvon, SD | 1 |
| Karlov, VA | 1 |
| Coull, BA | 2 |
| Dorfman, J | 1 |
| Rosenberger, PB | 1 |
| Carney, EW | 1 |
| Scialli, AR | 1 |
| Watson, RE | 1 |
| DeSesso, JM | 1 |
| Saygan-Karamursel, B | 1 |
| Guven, S | 1 |
| Onderoglu, L | 1 |
| Deren, O | 1 |
| Durukan, T | 1 |
| Montouris, G | 1 |
| Schindlbeck, C | 1 |
| Janni, W | 1 |
| Friese, K | 1 |
| Kini, U | 1 |
| Vinten, J | 1 |
| Fryer, A | 1 |
| Mazzucchelli, I | 2 |
| Onat, FY | 1 |
| Specchio, LM | 1 |
| Neve, AL | 1 |
| Gatti, G | 1 |
| Ducray, F | 1 |
| Colin, P | 1 |
| Cartalat-Carel, S | 1 |
| Pelissou-Guyotat, I | 1 |
| Mahla, K | 1 |
| Audra, P | 1 |
| Gaucherand, P | 1 |
| Honnorat, J | 1 |
| Trouillas, P | 1 |
| Heuss, D | 1 |
| Phillips, H | 1 |
| Guven, MA | 1 |
| Batukan, C | 1 |
| Ceylaner, G | 1 |
| Uzel, M | 1 |
| Barqawi, R | 1 |
| Artama, M | 1 |
| Isojärvi, JI | 1 |
| Auvinen, A | 1 |
| Rezvani, M | 1 |
| Smith, JC | 1 |
| Wolff, MC | 1 |
| Eisenschenk, S | 1 |
| Holly, P | 1 |
| Viinikainen, K | 1 |
| Eriksson, K | 1 |
| Mönkkönen, A | 1 |
| Aikiä, M | 1 |
| Nieminen, P | 1 |
| Heinonen, S | 1 |
| Kälviäinen, R | 1 |
| Sidenius, P | 1 |
| Stoner, SC | 1 |
| Nelson, LA | 1 |
| Lea, JW | 1 |
| Marken, PA | 1 |
| Sommi, RW | 1 |
| Dahmen, MM | 1 |
| Narang, M | 1 |
| Shah, D | 1 |
| Natasha, G | 1 |
| Carta, M | 1 |
| Cimador, M | 1 |
| Giuffrè, M | 1 |
| Sergio, M | 1 |
| Di Pace, MR | 1 |
| De Grazia, E | 1 |
| Corsello, G | 1 |
| Puhó, EH | 1 |
| Szunyogh, M | 1 |
| Métneki, J | 1 |
| Wieck, A | 1 |
| Rao, S | 1 |
| Sein, K | 1 |
| Haddad, PM | 1 |
| Manent, JB | 1 |
| Jorquera, I | 1 |
| Depaulis, A | 1 |
| Ben-Ari, Y | 1 |
| Represa, A | 1 |
| Misirlioğlu, ED | 1 |
| Aliefendioğlu, D | 1 |
| Doğru, MT | 1 |
| Sanli, C | 1 |
| Oktay, A | 1 |
| Lutz, UC | 1 |
| Wiatr, G | 1 |
| Gaertner, HJ | 1 |
| Bartels, M | 1 |
| Markestad, T | 1 |
| Ulstein, M | 1 |
| Strandjord, RE | 1 |
| Aksnes, L | 1 |
| Aarskog, D | 1 |
| Hiilesmaa, VK | 4 |
| Teramo, K | 3 |
| Bardy, AH | 4 |
| Meinardi, H | 4 |
| Tokola, RA | 1 |
| Neuvonen, PJ | 2 |
| Cavalieri, RR | 1 |
| Pitt-Rivers, R | 1 |
| Friis, ML | 1 |
| Schmidt, D | 1 |
| Bruni, J | 1 |
| Albright, PS | 1 |
| Keränen, T | 1 |
| Sivenius, J | 1 |
| Rating, D | 2 |
| Jäger-Roman, E | 2 |
| Nau, H | 5 |
| Kuhnz, W | 4 |
| Helge, H | 2 |
| Eluma, FO | 2 |
| Sucheston, ME | 2 |
| Hayes, TG | 2 |
| Paulson, RB | 3 |
| Warfield, CA | 1 |
| Sereno Colo, JA | 1 |
| Domínguez Chavez, FJ | 1 |
| Núñez Gutiérrez, J | 1 |
| Murasaki, M | 1 |
| Okamoto, K | 1 |
| Takahashi, A | 1 |
| Nagai, T | 1 |
| Robertson, IG | 1 |
| Donnai, D | 1 |
| D'Souza, S | 1 |
| Butler, CD | 1 |
| El-Sayed, MG | 1 |
| Aly, AE | 1 |
| Kadri, M | 1 |
| Moustafa, AM | 1 |
| Deichl, A | 1 |
| Kunze, J | 1 |
| Höppener, RJ | 1 |
| Steldinger, R | 1 |
| Morselli, PL | 4 |
| Franco-Morselli, R | 1 |
| Paulson, GW | 2 |
| Aminoff, MJ | 1 |
| Dam, M | 3 |
| Philbert, A | 1 |
| Covanis, A | 1 |
| Gupta, AK | 1 |
| Jeavons, PM | 1 |
| Pedersen, A | 1 |
| Poskitt, EM | 1 |
| Hensey, OJ | 1 |
| Smith, CS | 1 |
| Sillanpää, M | 3 |
| Zenk, KE | 1 |
| Wray, SD | 1 |
| Hassell, TM | 1 |
| Johnston, MC | 1 |
| Tijhuis, GJ | 1 |
| Strijbos, JH | 1 |
| van Ermen, A | 1 |
| Offerman, JJ | 1 |
| Dubois, AE | 1 |
| Scolnik, D | 2 |
| Rovet, J | 1 |
| Gladstone, D | 1 |
| Czuchta, D | 1 |
| Gardner, HA | 1 |
| Gladstone, R | 1 |
| Ashby, P | 1 |
| Weksberg, R | 1 |
| Einarson, T | 1 |
| Jeret, JS | 1 |
| Thompson, WO | 1 |
| Lindbom, U | 1 |
| Sundqvist, A | 1 |
| Berg, A | 1 |
| Pienimäki, P | 4 |
| Hartikainen, AL | 1 |
| Arvela, P | 2 |
| Partanen, T | 1 |
| Herva, R | 1 |
| Pelkonen, O | 1 |
| Vähäkangas, K | 4 |
| Bernus, I | 2 |
| Hooper, WD | 2 |
| Dickinson, RG | 2 |
| Robinson, AG | 1 |
| Verbalis, JG | 1 |
| Oakeshott, P | 3 |
| Hunt, G | 1 |
| Ylagan, LR | 1 |
| Budorick, NE | 1 |
| Martin, PJ | 1 |
| Millac, PA | 1 |
| Martin-du Pan, RC | 1 |
| Rouiller, D | 1 |
| Kaneko, S | 1 |
| Otani, K | 1 |
| Kondo, T | 1 |
| Fukushima, Y | 1 |
| Kan, R | 1 |
| Takeda, A | 2 |
| Nakane, Y | 1 |
| Mowadat, HR | 1 |
| Kerr, EE | 1 |
| StClair, D | 1 |
| Morrison, C | 1 |
| Rieder, MJ | 1 |
| Omtzigt, JG | 2 |
| Los, FJ | 1 |
| Meijer, JW | 3 |
| Potter, WZ | 1 |
| Ketter, TA | 1 |
| Sachs, GS | 1 |
| Haeusler, MC | 1 |
| Hoellwarth, ME | 1 |
| Holzer, P | 1 |
| Gomita, Y | 2 |
| Furuno, K | 2 |
| Kawasaki, H | 1 |
| Albani, F | 1 |
| Riva, R | 1 |
| Baruzzi, A | 1 |
| Phillips, NK | 1 |
| Lockard, JS | 1 |
| Ceci, O | 1 |
| Loizzi, P | 1 |
| Caruso, G | 1 |
| Caradonna, F | 1 |
| Clemente, R | 1 |
| Ferreri, R | 1 |
| Fuchs, S | 1 |
| Isojärvi, J | 1 |
| Bennett, GD | 2 |
| Amore, BM | 1 |
| Wlodarczyk, B | 1 |
| Kalhorn, TF | 1 |
| Skiles, GL | 1 |
| Nelson, SD | 1 |
| Slattery, JT | 1 |
| Garza-Morales, S | 2 |
| Ibarra-Puig, JM | 1 |
| Poblano-Luna, A | 1 |
| Gilda Mayén-Molina, D | 1 |
| Córdova-López, S | 1 |
| Quattrini, A | 1 |
| Ortenzi, A | 1 |
| Paggi, A | 1 |
| Foschi, N | 1 |
| Quattrini, C | 1 |
| Chitayat, D | 2 |
| Farkas, LD | 1 |
| Ornoy, A | 2 |
| Cohen, E | 1 |
| Lampela, E | 1 |
| Hakkola, J | 1 |
| Raunio, H | 1 |
| Belmont-Gomez, A | 1 |
| Ibarra-Puig, J | 1 |
| López-Ugalde, V | 1 |
| Morales-Garcia, A | 1 |
| Kunhardt-Rasch, J | 1 |
| Kayemba Kay'S, S | 1 |
| Beust, M | 1 |
| Aboulghit, H | 1 |
| Voisin, M | 1 |
| Mourtada, A | 1 |
| Brent, NB | 1 |
| Azarbayjani, F | 1 |
| Danielsson, BR | 1 |
| Baptista, T | 1 |
| Araujo, H | 1 |
| Rada, P | 1 |
| Hernández, L | 1 |
| Tueth, MJ | 1 |
| Murphy, TK | 1 |
| Evans, DL | 1 |
| Sutcliffe, AG | 1 |
| Jones, RB | 1 |
| Woodruff, G | 1 |
| Al Bunyan, M | 1 |
| Abo-Talib, Z | 1 |
| Haddad, IK | 1 |
| Shamo'on, H | 1 |
| Salah, S | 1 |
| Champel, V | 1 |
| Radal, M | 1 |
| Moulin-Vallez, M | 1 |
| Jonville-Béra, AP | 1 |
| Autret-Leca, E | 1 |
| Canger, R | 1 |
| Canevini, MP | 1 |
| Fumarola, C | 1 |
| Guidolin, L | 1 |
| Vignoli, A | 1 |
| Mamoli, D | 1 |
| Palmieri, C | 1 |
| Molteni, F | 1 |
| Granata, T | 1 |
| Hassibi, P | 1 |
| Zamperini, P | 1 |
| Pardi, G | 1 |
| Avanzini, G | 1 |
| Hashimoto, LN | 1 |
| Bass, WT | 1 |
| Green, GA | 1 |
| Werner, AL | 1 |
| Reagan, TJ | 1 |
| Goldman, WJ | 1 |
| Chaudron, LH | 1 |
| Jefferson, JW | 1 |
| Moore, SJ | 1 |
| Turnpenny, P | 1 |
| Quinn, A | 1 |
| Glover, S | 1 |
| Lloyd, DJ | 1 |
| Montgomery, T | 1 |
| Dean, JC | 1 |
| Ebbesen, F | 1 |
| Joergensen, A | 1 |
| Hoseth, E | 1 |
| Kaad, PH | 1 |
| Moeller, M | 1 |
| Holsteen, V | 1 |
| Rix, M | 1 |
| Fairgrieve, SD | 1 |
| Jackson, M | 1 |
| Jonas, P | 1 |
| Walshaw, D | 1 |
| White, K | 1 |
| Montgomery, TL | 1 |
| Burn, J | 1 |
| Lynch, SA | 1 |
| Griswold, KS | 1 |
| Pessar, LF | 1 |
| Ambrósio, AF | 1 |
| Silva, AP | 1 |
| Araújo, I | 1 |
| Malva, JO | 1 |
| Soares-da-Silva, P | 1 |
| Carvalho, AP | 1 |
| Carvalho, CM | 1 |
| Iqbal, MM | 2 |
| Gundlapalli, SP | 1 |
| Ryan, WG | 1 |
| Ryals, T | 1 |
| Passman, TE | 1 |
| Harvey, EA | 1 |
| Huntington, KB | 1 |
| Khoshbin, S | 1 |
| Hayes, AM | 1 |
| Ryan, LM | 1 |
| Kalis, MM | 1 |
| Huff, NA | 1 |
| Lyszkiewicz, DA | 1 |
| Gerichhausen, S | 1 |
| Björnsdóttir, I | 1 |
| Einarson, TR | 1 |
| Einarson, A | 1 |
| Johnson, KA | 2 |
| Weber, PA | 1 |
| Jones, KL | 2 |
| Diav-Citrin, O | 1 |
| Shechtman, S | 1 |
| Arnon, J | 1 |
| Leppik, IE | 1 |
| Sohhan, T | 1 |
| Mahmud, SZ | 1 |
| Arroyo, S | 1 |
| Gupta, G | 1 |
| Bansal, A | 1 |
| Singh, M | 1 |
| Myllynen, P | 1 |
| Jouppila, P | 1 |
| Frey, B | 2 |
| Braegger, CP | 1 |
| Ghelfi, D | 1 |
| Avery, JK | 1 |
| Assael, BM | 2 |
| Bossi, L | 2 |
| Pynnönen, S | 2 |
| Livingston, S | 1 |
| Pruce, I | 1 |
| Pauli, LL | 1 |
| Aucamp, AK | 1 |
| Janz, D | 1 |
| Poser, W | 1 |
| Poser, S | 1 |
| Ritter, G | 1 |
| Gehlen, W | 1 |
| Conomy, JP | 1 |
| Reith, H | 1 |
| Schäfer, H | 1 |
| Swanson, PD | 1 |
| Windorfer, A | 1 |
| Stünkel, S | 1 |
| Jreissaty, S | 1 |
| Hicks, EP | 1 |
| Kanto, J | 2 |
| Erkkola, R | 1 |
| van der Kleijn, E | 2 |
| Vree, T | 1 |
| Guelen, P | 1 |
| Schobten, F | 1 |
| Westenberg, H | 1 |
| Knop, H | 1 |
| Vesterhus, P | 1 |
| Johannessen, SI | 1 |
| Niebyl, JR | 1 |
| Blake, DA | 1 |
| Freeman, JM | 2 |
| Luff, RD | 1 |
| Hvidberg, EF | 1 |
| Singer, HS | 1 |
| Sullivan, FM | 1 |
| McElhatton, PR | 1 |
| Garattini, S | 1 |
| Gerna, M | 1 |
| Gomeni, R | 1 |
| Kullander, S | 1 |
| Hempel, E | 1 |
| Klinger, W | 1 |
| Van Rees, H | 1 |
| Cereghino, JJ | 1 |
| Rane, A | 2 |
| Bertilsson, L | 3 |
| Palmér, L | 1 |
| Herkes, GK | 2 |
| Mor, N | 1 |
| Litwin, A | 1 |
| Coons, PM | 1 |
| Friel, PN | 3 |
| McCormick, K | 2 |
| Leavitt, A | 1 |
| Erickson, DM | 1 |
| McCormick, KB | 1 |
| Loewenson, RB | 1 |
| Sells, CJ | 2 |
| Benedetti, TJ | 1 |
| Gladstone, DJ | 1 |
| Bologa, M | 1 |
| Maguire, C | 1 |
| Pastuszak, A | 1 |
| Welty, TE | 1 |
| Pickering, PR | 1 |
| Hale, BC | 1 |
| Arazi, R | 1 |
| Lampe, H | 1 |
| Bigalke, H | 1 |
| Fröscher, W | 2 |
| Herrmann, R | 1 |
| Niesen, M | 2 |
| Bülau, P | 1 |
| Penin, H | 1 |
| Hildenbrand, G | 1 |
| Tanaka, H | 1 |
| Izumi, M | 1 |
| Okada, H | 1 |
| Ishikawa, S | 1 |
| Nygaard, TG | 1 |
| Marsden, CD | 1 |
| Fahn, S | 1 |
| Hunt, GM | 1 |
| van der Pol, MC | 1 |
| Hadders-Algra, M | 1 |
| Huisjes, HJ | 1 |
| Touwen, BC | 1 |
| Rosa, FW | 1 |
| Legido, A | 1 |
| Toomey, K | 1 |
| Goldsmith, L | 1 |
| Vestermark, V | 1 |
| Vestermark, S | 1 |
| Cohen, LS | 2 |
| Heller, VL | 2 |
| Araki, Y | 1 |
| Fukuda, T | 1 |
| McParland, P | 2 |
| Pearce, JM | 2 |
| Schubiger, G | 1 |
| Musy, JP | 1 |
| Zona, C | 1 |
| Tancredi, V | 1 |
| Palma, E | 1 |
| Pirrone, GC | 1 |
| Avoli, M | 1 |
| Gaily, EK | 1 |
| Koerner, M | 1 |
| Van Allen, M | 1 |
| Leavitt, AM | 1 |
| Yerby, JA | 1 |
| Saunders, M | 1 |
| Chadwick, D | 1 |
| Piccione, E | 1 |
| Ticconi, C | 1 |
| Cennamo, M | 1 |
| Pellock, JM | 1 |
| Lacro, RV | 1 |
| Knott, C | 1 |
| Reynolds, F | 1 |
| Bag, S | 1 |
| Behari, M | 1 |
| Ahuja, GK | 1 |
| Karmarkar, MG | 1 |
| Rapport, DJ | 1 |
| Calabrese, JR | 2 |
| Pacifici, GM | 1 |
| Mohl, VK | 1 |
| Taylor, SM | 1 |
| Shinnar, S | 1 |
| Bertollini, R | 1 |
| Mastroiacovo, P | 1 |
| Robert, E | 1 |
| Ratsula, K | 1 |
| Wladimiroff, JW | 1 |
| Stewart, PA | 1 |
| Reuss, A | 1 |
| van Swaay, E | 1 |
| Sachs, ES | 1 |
| Farrell, K | 1 |
| Anderson, L | 1 |
| Hall, JG | 1 |
| Rosenbaum, JF | 1 |
| Gulledge, AD | 1 |
| Mueller, PS | 1 |
| Kuoppala, T | 1 |
| Tuimala, R | 1 |
| Koskinen, T | 1 |
| Dalessio, DJ | 1 |
| Löscher, W | 1 |
| Levy, RH | 1 |
| Bell, AD | 1 |
| Gerlis, LM | 1 |
| Variend, S | 1 |
| Duncan, JS | 1 |
| Ekbom, K | 1 |
| Sjöqvist, F | 1 |
| Miller, DQ | 1 |
| Regli, F | 1 |
| Danks, DM | 1 |
| Barry, JE | 1 |
| Sheffield, LJ | 1 |
| Elian, M | 1 |
| Meyer, JG | 1 |
| Loiseau, P | 1 |
| Henry, TP | 1 |
| Redpath, TH | 1 |
| Gayford, JJ | 1 |
| Fernandez, VE | 1 |
| Vestergård, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Physiological-based Pharmacokinetics Approach to Determine the Extent of Drug Exposure of Antiseizure Medications During Pregnancy and Breastfeeding[NCT05450978] | 60 participants (Anticipated) | Observational [Patient Registry] | 2022-07-20 | Recruiting | |||
| A Pilot Study of Prophylactic Management of Lamotrigine for Bipolar Disorder in Pregnant Women[NCT03774641] | 20 participants (Anticipated) | Observational | 2018-12-03 | Recruiting | |||
| The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822] | 550 participants (Anticipated) | Observational | 2022-02-18 | Recruiting | |||
| Homeopathic Treatment in Pregnant Women With Overweight and Mental Disorder: a Double Blinded Controlled Clinical Trial[NCT00942097] | Phase 2/Phase 3 | 134 participants (Actual) | Interventional | 2009-08-31 | Completed | ||
| The Effect of Single Dose Carbamazepine on the Pharmacokinetics of Single Dose Nevirapine (Viramune, NVP) and Development of NVP Resistance, PMTCT Program of Moshi, Tanzania (VITA1)[NCT00294892] | Phase 2 | 144 participants (Actual) | Interventional | 2006-02-28 | Completed | ||
| Effects and Consequences for Mother and Child From Treatment for Depression, A Prospective Randomized, Placebo- Controlled, Trial With Internet-based Cognitive Behavior Therapy and Sertraline or Placebo for Moderate Depression in Pregnancy[NCT02185547] | Phase 4 | 17 participants (Actual) | Interventional | 2016-02-21 | Terminated (stopped due to Difficulties in recruiting participants.) | ||
| A Study of Divalproex Sodium in Children With Autism Spectrum Disorder and Epileptiform EEG[NCT01170325] | Phase 2 | 0 participants (Actual) | Interventional | 2010-06-30 | Withdrawn | ||
| Neurodevelopmental Effects of Antiepileptic Drugs II: the NEAD Study[NCT00021866] | 331 participants (Actual) | Observational | 2000-09-30 | Completed | |||
| Prophylactic Use of Immediate Postpartum Sertraline to Prevent Postpartum Depression: A Double Blind Randomized Placebo Controlled Trial[NCT02235064] | 2 participants (Actual) | Interventional | 2014-07-31 | Terminated (stopped due to Low recruitment, completion of funding cycle) | |||
| A Preliminary Study of the Efficacy and Safety of Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency[NCT01379469] | Phase 2 | 20 participants (Actual) | Interventional | 2012-01-31 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The Antidepressant Side-Effect Checklist (ASEC) was employed to detect any adverse reaction to treatment regimens (NCT02235064)
Timeframe: Discharge from hospital to 12 weeks postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Sertraline | 0 |
| Placebo | 1 |
"Patients met with single psychiatrist (co-investigator), blinded to group assignment, who evaluated the patient using Edinburgh Postpartum Depression Screen, Hamilton Depression Rating Scale, Global Assessment of Functioning Scale, and clinical assessment~0 = No postpartum depression up to 12 weeks following discharge from hospital~1 = Postpartum depression up to 12 weeks following discharge from hospital" (NCT02235064)
Timeframe: Discharge from hospital to 12 weeks postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Sertraline | 0 |
| Placebo | 0 |
(NCT02235064)
Timeframe: 12 weeks postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Sertraline | 0 |
| Placebo | 0 |
(NCT02235064)
Timeframe: 4 weeks postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Sertraline | 0 |
| Placebo | 0 |
(NCT02235064)
Timeframe: 8 weeks postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Sertraline | 0 |
| Placebo | 0 |
(NCT02235064)
Timeframe: 12 weeks postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Sertraline | 0 |
| Placebo | 0 |
(NCT02235064)
Timeframe: 4 weeks postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Sertraline | 0 |
| Placebo | 0 |
(NCT02235064)
Timeframe: 8 weeks postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Sertraline | 0 |
| Placebo | 0 |
(NCT02235064)
Timeframe: 12 weeks postpartum
| Intervention | Grams (Mean) |
|---|---|
| Sertraline | 5301 |
| Placebo | 4734 |
(NCT02235064)
Timeframe: 4 weeks postpartum
| Intervention | Grams (Mean) |
|---|---|
| Sertraline | 3033 |
| Placebo | 2750 |
(NCT02235064)
Timeframe: 8 weeks postpartum
| Intervention | Grams (Mean) |
|---|---|
| Sertraline | 5301 |
| Placebo | 3685 |
62 reviews available for carbamazepine and Pregnancy
| Article | Year |
|---|---|
Psychotropic drug use in perinatal women with bipolar disorder.
Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Drug Elimination Routes; Fe | 2020 |
Population Pharmacokinetics of Levetiracetam: A Systematic Review.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Female; Humans; Infant, Newborn; Levetiracetam; Phenyt | 2021 |
Use of Phenytoin, Phenobarbital Carbamazepine, Levetiracetam Lamotrigine and Valproate in Pregnancy and Breastfeeding: Risk of Major Malformations, Dose-dependency, Monotherapy vs Polytherapy, Pharmacokinetics and Clinical Implications.
Topics: Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam | 2021 |
Pregnancy Outcomes Following In Utero Exposure to Lamotrigine: A Systematic Review and Meta-Analysis.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newbo | 2017 |
In Utero Oxcarbazepine Exposure and Neonatal Abstinence Syndrome: Case Report and Brief Review of the Literature.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Male; Neonatal Abstinence Sy | 2017 |
Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta-analysis.
Topics: Anticonvulsants; Autistic Disorder; Bayes Theorem; Breast Feeding; Carbamazepine; Child; Epilepsy; F | 2017 |
Is there consensus across international evidence-based guidelines for the psychotropic drug management of bipolar disorder during the perinatal period?
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Bre | 2018 |
Adverse outcomes during pregnancy and major congenital malformations in infants of patients with bipolar and schizoaffective disorders treated with antiepileptic drugs: A systematic review.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Bipolar Disorder; Carbamazepine; Female; Humans | 2019 |
Seizures and intracranial hemorrhage.
Topics: Anticonvulsants; Carbamazepine; Congenital Abnormalities; Eclampsia; Epilepsy; Female; Folic Acid; H | 2013 |
Pharmacotherapy for mood disorders in pregnancy: a review of pharmacokinetic changes and clinical recommendations for therapeutic drug monitoring.
Topics: Antidepressive Agents; Carbamazepine; Drug Monitoring; Female; Humans; Lamotrigine; Mood Disorders; | 2014 |
Developmental neurotoxicity and anticonvulsant drugs: a possible link.
Topics: Animals; Anticonvulsants; Breast Feeding; Carbamazepine; Cognition Disorders; Developmental Disabili | 2014 |
Treatment for epilepsy in pregnancy: neurodevelopmental outcomes in the child.
Topics: Age Factors; Anticonvulsants; Carbamazepine; Child; Developmental Disabilities; Epilepsy; Female; Hu | 2014 |
Is carbamazepine a human teratogen?
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Australia; Carbamazepine; Epilepsy; Female; Fet | 2016 |
[Preconceptional and perinatal challenges of pregnancy in women with epilepsy].
Topics: Adult; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epileps | 2016 |
Epilepsy treatment in adults and adolescents: Expert opinion, 2016.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Depression; Double-Blind Method; Dru | 2017 |
Perinatal depression: treatment options and dilemmas.
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Case-Control Studies; Cyclohexan | 2008 |
Epileptic disorders in pregnancy: an overview.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Folic Acid; Hemorrhag | 2008 |
Fetal malformations associated with the use of methylphenobarbital and carbamazepine during pregnancy. Two case reports and review of the literature.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; | 2009 |
Managing antiepileptic drugs during pregnancy and lactation.
Topics: Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Humans; Infant; Lactation; Lamotri | 2009 |
Mood stabilizers in pregnancy: a systematic review.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Carbamazepin | 2010 |
Intrauterine exposure to carbamazepine and specific congenital malformations: systematic review and case-control study.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Case-Control Studies; Epilepsy; Europe; | 2010 |
Side effects of phenobarbital in epilepsy: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Child; Cognition Disorders; Cohort Studies; Cross-Over Studies; Data | 2011 |
Is there an association between maternal carbamazepine use during pregnancy and eye malformations in the child?
Topics: Carbamazepine; Databases as Topic; Epilepsy; Eye Abnormalities; Female; Humans; Incidence; Netherlan | 2002 |
Pathobiology and genetics of neural tube defects.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; Female; Folic Acid; Genetic Predisposition to Dis | 2003 |
Management issues for women with epilepsy: neural tube defects and folic acid supplementation.
Topics: Adult; Animals; Anticonvulsants; Carbamazepine; Cleft Lip; Cleft Palate; Epilepsy; Female; Folic Aci | 2003 |
Management of bipolar disorder during pregnancy and the postpartum period.
Topics: Adolescent; Adult; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbam | 2004 |
[Therapy of epilepsy: current strategy and tactics].
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Child; | 2004 |
Mechanisms regulating toxicant disposition to the embryo during early pregnancy: an interspecies comparison.
Topics: Animals; Biological Transport; Carbamazepine; Embryonic Development; Female; Humans; Maternal-Fetal | 2004 |
Safety of the newer antiepileptic drug oxcarbazepine during pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Carbamazepine; Female; Humans; Oxcarba | 2005 |
Does vitamin K prophylaxis prevent bleeding in neonates exposed to enzyme-inducing antiepileptic drugs in utero?
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Pregnancy; Prenatal Exposure Delaye | 2006 |
Historical review of carbamazepine for the treatment of bipolar disorder.
Topics: Antimanic Agents; Bipolar Disorder; Carbamazepine; Controlled Clinical Trials as Topic; Delayed-Acti | 2007 |
Antiepileptic drugs as human teratogens.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital | 2008 |
ACOG Practice Bulletin: Clinical management guidelines for obstetrician-gynecologists number 92, April 2008 (replaces practice bulletin number 87, November 2007). Use of psychiatric medications during pregnancy and lactation.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Anxiety Disorders; Bipolar Disorder; Breast Feed | 2008 |
The effects of drugs on the distribution and metabolism of thyroid hormones.
Topics: Animals; Antithyroid Agents; Carbamazepine; Carcinogens; Female; Heparin; Hormones; Humans; Male; Ph | 1981 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Hal | 1984 |
Clinical pharmacokinetics of antiepileptic drugs in adults.
Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Disease; Ethosuximide; Female; H | 1980 |
The epileptic mother and her child.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Fetal | 1982 |
An overview of perinatal clinical pharmacology.
Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digo | 1981 |
Pharmacological issues in the treatment of bipolar disorder: focus on mood-stabilizing compounds.
Topics: Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Carbamazepine; Drug Interactions; Female; | 1993 |
Bipolar mood disorder: practical strategies for acute and maintenance phase treatment.
Topics: Acute Disease; Adult; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Clinical T | 1996 |
[Carbamazepine].
Topics: Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child; Drug Monitoring; Female; Humans; Pr | 1995 |
Carbamazepine clinical pharmacology: a review.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Mental Disorders; Pregnancy | 1995 |
Special considerations: use of lithium in children, adolescents, and elderly populations.
Topics: Abnormalities, Drug-Induced; Acetates; Adolescent; Adult; Age Factors; Aged; Amines; Anticonvulsants | 1998 |
Mood stabilizers during breastfeeding: a review.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Breast Feeding; Carbamazepine; Cyclohexanecarbo | 2000 |
Management of bipolar disorder.
Topics: Adolescent; Adult; Age Distribution; Antimanic Agents; Bipolar Disorder; Carbamazepine; Child, Presc | 2000 |
Effects of antimanic mood-stabilizing drugs on fetuses, neonates, and nursing infants.
Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Antimanic Agents; Benzodiazepines; Breast Feed | 2001 |
Oxcarbazepine, an antiepileptic agent.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; | 2001 |
Treatment of epilepsy in 3 specialized populations.
Topics: Age Factors; Aged; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Epilepsy; Female; Human | 2001 |
The effects of lithium, valproic acid, and carbamazepine during pregnancy and lactation.
Topics: Adult; Anticonvulsants; Antimanic Agents; Carbamazepine; Female; Humans; Lactation; Lithium; Pregnan | 2001 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, | 1979 |
The teratogenic risk of antiepileptic drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anencephaly; Anti-Anxiety Agents; Anticonvulsa | 1975 |
[Iatrogenic damage possibilities in the drug therapy of neurologic and psychiatric diseases].
Topics: Amantadine; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Central Nervous System Di | 1977 |
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data].
Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; | 1979 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam | 1976 |
Spina bifida in infants of women treated with carbamazepine during pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Epilepsy; Female; Human | 1991 |
Restless legs syndrome in pregnancy. Case reports.
Topics: Carbamazepine; Female; Humans; Pregnancy; Pregnancy Complications; Restless Legs Syndrome | 1990 |
Epilepsy in women of childbearing age.
Topics: Carbamazepine; Epilepsy; Female; Humans; Pregnancy; Pregnancy Complications | 1989 |
[Problems of neurological drug therapy in pregnancy].
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Antiparkinson Agents; Carbamazepine; Chelating Agents; | 1989 |
Efficacy and adverse effects of antiepileptic drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital | 1989 |
Antiepileptic drugs in adolescents.
Topics: Adaptation, Psychological; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Dru | 1987 |
Problems and management of the pregnant woman with epilepsy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Pregnancy; Pr | 1987 |
Current concepts. Seizure disorders and pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Administration Schedule; Epilepsy; | 1985 |
8 trials available for carbamazepine and Pregnancy
| Article | Year |
|---|---|
AntiEpileptic drug Monitoring in PREgnancy (EMPiRE): a double-blind randomised trial on effectiveness and acceptability of monitoring strategies.
Topics: Anticonvulsants; Carbamazepine; Double-Blind Method; Drug Monitoring; Epilepsy; Female; Humans; Lamo | 2018 |
Intrapartum single-dose carbamazepine reduces nevirapine levels faster and may decrease resistance after a single dose of nevirapine for perinatal HIV prevention.
Topics: Adolescent; Adult; Carbamazepine; CD4 Lymphocyte Count; Chi-Square Distribution; Drug Interactions; | 2012 |
Major malformations in offspring of women with epilepsy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Logistic Mode | 2003 |
Evaluation of antiepileptic drugs in pregnancy in a Jordanian army hospital.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Clinical Protocols; Drug Monitor | 2005 |
In utero antiepileptic drug exposure: fetal death and malformations.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Cognition; Female; Fetal Death; | 2006 |
Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications.
Topics: Adult; Carbamazepine; Cohort Studies; Craniofacial Abnormalities; Epilepsy; Female; Fingers; Humans; | 1997 |
Effects of pregnancy on various pathways of human antiepileptic drug metabolism.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Phenytoin; Pregnancy; Pregnancy Complications | 1997 |
[Treatment of vascular headaches].
Topics: Adrenergic beta-Antagonists; Carbamazepine; Cerebrovascular Disorders; Clonidine; Ergotamine; Female | 1973 |
306 other studies available for carbamazepine and Pregnancy
| Article | Year |
|---|---|
Quantitative prediction of CYP2B6 induction by estradiol during pregnancy: potential explanation for increased methadone clearance during pregnancy.
Topics: Analgesics, Opioid; Aryl Hydrocarbon Hydroxylases; Biotransformation; Bupropion; Carbamazepine; Cell | 2013 |
Levetiracetam, lamotrigine and carbamazepine: which monotherapy during pregnancy?
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Lamotrigine; Levetiracetam; Pregnancy; Retrospective | 2022 |
Neuropsychological effects in children exposed to anticonvulsant monotherapy during gestation: Phenobarbital, carbamazepine, and phenytoin.
Topics: Anticonvulsants; Carbamazepine; Child; Female; Humans; Intelligence Tests; Phenobarbital; Phenytoin; | 2022 |
Antiseizure Medication Concentrations During Pregnancy: Results From the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) Study.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lacosamide; Lamotrigine; Levetirace | 2022 |
Carbamazepine and carbamazepine-epoxide concentrations in mothers, colostrum, and breastfed newborns: Comparison with concentrations determined during delivery and in the mature milk period.
Topics: Anticonvulsants; Benzodiazepines; Breast Feeding; Carbamazepine; Cohort Studies; Colostrum; Epoxy Co | 2022 |
Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability.
Topics: Anticonvulsants; Autism Spectrum Disorder; Autistic Disorder; Carbamazepine; Child; Cohort Studies; | 2022 |
Prenatal Carbamazepine Exposure and Academic Performance in Adolescents: A Population-Based Cohort Study.
Topics: Academic Performance; Adolescent; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Cohort Stu | 2023 |
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep | 2023 |
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep | 2023 |
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep | 2023 |
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep | 2023 |
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep | 2023 |
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep | 2023 |
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep | 2023 |
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep | 2023 |
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep | 2023 |
Prenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders.
Topics: Adolescent; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Carbamazepine; Child; Ch | 2023 |
Specific fetal malformations following intrauterine exposure to antiseizure medication.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Australia; Carbamazepine; Female; Humans; Male; Pregna | 2023 |
Birth outcomes in pregnant women with epilepsy: A Nationwide multicenter study from Türkiye.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant; Infant, Newborn; Lamotrigine; Preg | 2023 |
External validation of the AntiEpileptic Drug Monitoring in PREgnancy (EMPiRE) model for predicting seizures in pregnant women with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Cohort Studies; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam | 2023 |
Genotoxicity assessment of antiepileptic drugs (AEDs) in human embryonic stem cells.
Topics: Anticonvulsants; Carbamazepine; DNA Damage; Epilepsy; Female; Human Embryonic Stem Cells; Humans; La | 2019 |
Language impairment in children aged 5 and 8 years after antiepileptic drug exposure in utero - the Norwegian Mother and Child Cohort Study.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cohort Studies; Epilepsy; Female; Humans; L | 2020 |
Anti-epileptic drug and folic acid usage during pregnancy, seizure and malformation outcomes: Changes over two decades in the Kerala Registry of Epilepsy and Pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Folic Acid; Humans; India; Lamotrigine; Levetiracetam | 2020 |
[New recommendations for antiepileptic drug therapy: the last piece in the review of epilepsy care].
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Pregnancy; Pre | 2020 |
Neurocognition after prenatal levetiracetam, lamotrigine, carbamazepine or valproate exposure.
Topics: Anticonvulsants; Carbamazepine; Child; Child Development; Cognitive Dysfunction; Female; Humans; Lam | 2020 |
Maternal CBZ exposure impairs testicular development, spermatogenesis and sperm parameters in male offspring at puberty.
Topics: Animals; Carbamazepine; Female; Humans; Male; Placenta; Pregnancy; Puberty; Rats; Spermatogenesis; S | 2020 |
Involuntary human exposure to carbamazepine: A cross-sectional study of correlates across the lifespan and dietary spectrum.
Topics: Aged; Agricultural Irrigation; Carbamazepine; Child; Child, Preschool; Cross-Sectional Studies; Diet | 2020 |
Antiseizure medication use during pregnancy and risk of ASD and ADHD in children.
Topics: Adolescent; Adult; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Autism Spectrum D | 2020 |
Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Intellectual Disability and Delayed Childhood Milestones.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Denmark; Developmen | 2020 |
Epilepsy surveillance in normocephalic children with and without prenatal Zika virus exposure.
Topics: Anticonvulsants; Carbamazepine; Cohort Studies; Electroencephalography; Epilepsy; Female; Grenada; H | 2020 |
Antiepileptic drugs and depression during pregnancy in women with epilepsy.
Topics: Adult; Anticonvulsants; Australia; Carbamazepine; Depression; Epilepsy; Female; Humans; Levetiraceta | 2020 |
Thyroid hormones, Sertoli cell proliferation and differentiation in progenies from carbamazepine-treated rat dams during pregnancy and lactation.
Topics: Animals; Carbamazepine; Cell Differentiation; Cell Proliferation; Female; Lactation; Male; Pregnancy | 2021 |
Effects of antiepileptic drugs' administration during pregnancy on the nerve cell proliferation and axonal outgrowth of human neuroblastoma SH-SY5Y nerve cells.
Topics: Anticonvulsants; Carbamazepine; Cell Line, Tumor; Cell Proliferation; Child; Epilepsy; Female; Human | 2021 |
Anti-epileptic drug exposure and risk of foetal death in utero.
Topics: Adult; Anticonvulsants; Australia; Carbamazepine; Epilepsy; Female; Fetal Death; Humans; Pregnancy; | 2018 |
Mood-Stabilizing Anticonvulsants, Spina Bifida, and Folate Supplementation: Commentary.
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Dietary Supplements; Female; Fol | 2018 |
Maternal Carbamazepine Therapy and Unusual Adverse Effects in a Breastfed Infant.
Topics: Adult; Anticonvulsants; Bottle Feeding; Breast Feeding; Carbamazepine; Child of Impaired Parents; Ep | 2018 |
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug | 2018 |
Obstetric outcomes and effects on babies born to women treated for epilepsy during pregnancy in a resource limited setting: a comparative cohort study.
Topics: Abortion, Spontaneous; Adolescent; Adult; Anticonvulsants; Body Height; Body Weight; Carbamazepine; | 2018 |
Memory dysfunction in school-aged children exposed prenatally to antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsy; Female; Hu | 2018 |
Fetal antiepileptic drug exposure and learning and memory functioning at 6 years of age: The NEAD prospective observational study.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Lamotrigine; Learning; Memor | 2019 |
Developmental outcomes at age four following maternal antiepileptic drug use.
Topics: Adult; Anticonvulsants; Carbamazepine; Child Development; Child, Preschool; Cohort Studies; Epilepsy | 2019 |
Preconceptional paternal antiepileptic drugs use and risk of congenital anomalies in offspring: a nationwide cohort study.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cohort Studies; Denmark; Epilepsy; F | 2019 |
Behavioral problems in children of mothers with epilepsy prenatally exposed to valproate, carbamazepine, lamotrigine, or levetiracetam monotherapy.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child Behavior Disorders; Epilepsy; Female; Humans; La | 2019 |
Retrospective Analysis of Oxcarbazepine in Pregnant Women With Substance Use Disorders: Focus on Safety.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Oxcarbazepine; Pregnancy; Pregnant | 2021 |
In utero oxcarbazepine and a withdrawal syndrome, anomalies, and hyponatremia.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Hyponatremia; Infant; Oxcarbazepine; Pregn | 2013 |
Acute oxcarbazepine-induced hepatotoxicity in a patient susceptible to developing drug-induced liver injury.
Topics: Acridines; Carbamazepine; Chemical and Drug Induced Liver Injury; Delivery, Obstetric; Female; Human | 2013 |
Sirenomelia after phenobarbital and carbamazepine therapy in pregnancy.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Ectromelia; Epilepsy; Fatal Outcome; Female; Humans; Phe | 2013 |
[Klüver-Bucy syndrome after herpes simplex encephalitis].
Topics: Adolescent; Anticonvulsants; Brain Edema; Carbamazepine; Encephalitis, Herpes Simplex; Female; Herpe | 2013 |
Seizure control and treatment changes in pregnancy: observations from the EURAP epilepsy pregnancy registry.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Lamotrigine; Phenobarbital; Pregnancy; Pregnancy Com | 2013 |
Carbamazepine-exposure during gestation and lactation affects pubertal onset and spermatic parameters in male pubertal offspring.
Topics: Animals; Anticonvulsants; Carbamazepine; Estradiol; Female; Lactation; Luteinizing Hormone; Male; Ma | 2014 |
Malformation in index pregnancy in women with epilepsy is not followed by recurrence in subsequent pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; India; Pregna | 2013 |
Prenatal exposure to carbamazepine reduces hippocampal and cortical neuronal cell population in new-born and young mice without detectable effects on learning and memory.
Topics: Amygdala; Animals; Carbamazepine; Cerebral Cortex; Female; Hippocampus; Immunohistochemistry; Learni | 2013 |
Teratogenic potential of antiepileptic drugs in the zebrafish model.
Topics: Acetamides; Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Ethosuximide; Female; F | 2013 |
Malformation risks of antiepileptic drug monotherapies in pregnancy: updated results from the UK and Ireland Epilepsy and Pregnancy Registers.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug | 2014 |
Carbamazepine clearance and seizure stability during pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Pregnancy; Pregnancy Complications; | 2014 |
Reduction of nevirapine-driven HIV mutations by carbamazepine is modulated by CYP3A activity.
Topics: Anti-HIV Agents; Carbamazepine; Chemoprevention; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Indu | 2014 |
Association of certain chronic maternal diseases with the risk of specific congenital heart defects: a population-based study.
Topics: Adult; Anticonvulsants; Aortic Coarctation; Carbamazepine; Case-Control Studies; Chronic Disease; Di | 2014 |
IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child Development; Epilepsy; Female; Humans; Intellige | 2015 |
Fine-tuning risk assessment with antiepileptic drug use in pregnancy.
Topics: Anticonvulsants; Carbamazepine; Child Development; Epilepsy; Female; Humans; Intelligence; Lamotrigi | 2015 |
Teratogenic effect of Carbamazepine use during pregnancy in the mice.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Female; Fetal Growth Retardati | 2015 |
Valproate and pregnancy: think again.
Topics: Anticonvulsants; Carbamazepine; Child Development; Epilepsy; Female; Humans; Intelligence; Lamotrigi | 2015 |
Oxcarbazepine-loaded polymeric nanoparticles: development and permeability studies across in vitro models of the blood-brain barrier and human placental trophoblast.
Topics: Blood-Brain Barrier; Carbamazepine; Cell Line; Cell Membrane Permeability; Female; Humans; Lactic Ac | 2015 |
Aortopulmonary collateral artery in prenatal exposure to carbamazepine - endovascular therapy and technical considerations: a case report.
Topics: Anticonvulsants; Aorta; Carbamazepine; Child; Embolization, Therapeutic; Female; Heart Defects, Cong | 2015 |
[Valproic acid responsible for low IQ].
Topics: Anticonvulsants; Carbamazepine; Child Development; Epilepsy; Female; Humans; Intelligence; Male; Pre | 2015 |
Fine-tuning risk assessment with antiepileptic drug use in pregnancy.
Topics: Anticonvulsants; Carbamazepine; Child Development; Epilepsy; Female; Humans; Intelligence; Male; Pre | 2015 |
Use of antiepileptic drugs during pregnancy and lactation: Type of information provided by searching Google.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans | 2016 |
Concentrations of carbamazepine and carbamazepine-10,11-epoxide in maternal and umbilical cord blood at birth: Influence of co-administration of valproic acid or enzyme-inducing antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Dose-Response Relationsh | 2016 |
Maternal exposure to carbamazepine at environmental concentrations can cross intestinal and placental barriers.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Female; Fluoxetine; Intestinal Absorption; Liver; Ma | 2016 |
Induction of the UDP-Glucuronosyltransferase 1A1 during the Perinatal Period Can Cause Neurodevelopmental Toxicity.
Topics: Animals; Animals, Newborn; Brain; Carbamazepine; Cell Movement; Enzyme Induction; Female; Gene Expre | 2016 |
Comparative study of antiepileptic drug use during pregnancy over a period of 12 years in Spain. Efficacy of the newer antiepileptic drugs lamotrigine, levetiracetam, and oxcarbazepine.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Longitu | 2018 |
Prenatal exposure to antiepileptic drugs and use of primary healthcare during childhood: a population-based cohort study in Denmark.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Denmark; Epilepsy; Femal | 2017 |
Maternal carbamazepine alters fetal neuroendocrine-cytokines axis.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebellum; Cytokines; Female; Fetus; Growth Hormone; Hypot | 2017 |
The effect of carbamazepine on etonogestrel concentrations in contraceptive implant users.
Topics: Adult; Anticonvulsants; Body Mass Index; Carbamazepine; Contraceptive Agents, Female; Cross-Over Stu | 2017 |
Unilateral radius aplasia due to lamotrigine and oxcarbazepine use in pregnancy.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Lamotrigine; Maxillofacial Abnormal | 2008 |
Seizure deterioration in women treated with oxcarbazepine during pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Oxcarbazepine; Pregnancy; Pregnancy Complicat | 2009 |
Changing trends in antiepileptic drug prescribing in girls of child-bearing potential.
Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Child; Contraceptive Agents | 2009 |
Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child, Preschool; Cognition; Developmental Disabilities; Dose | 2009 |
[Fetal malformations in women with epilepsy].
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Bulgaria; Carbamazepine; Epilepsy; Female; Humans; Inf | 2009 |
Histologic and morphologic effects of valproic acid and oxcarbazepine on rat uterine and ovarian cells.
Topics: Animals; Anticonvulsants; Apoptosis; Carbamazepine; Cell Count; Cytoplasm; Embryo Implantation; Endo | 2010 |
Pregnancy treatment guidelines: throwing the baby out with the bath water.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Femal | 2009 |
Neurocysticercosis in the infant of a pregnant mother with a tapeworm.
Topics: Albendazole; Animals; Anthelmintics; Anti-Inflammatory Agents; Anticonvulsants; Carbamazepine; Dexam | 2009 |
A prospective study of cognitive fluency and originality in children exposed in utero to carbamazepine, lamotrigine, or valproate monotherapy.
Topics: Analysis of Variance; Anticonvulsants; Carbamazepine; Child, Preschool; Cognition; Creativity; Epile | 2009 |
Teratogenic effects of carbamazepine on embryonic eye development in pregnant mice.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Analgesics, Non-Narcotic; Animals; Anticonvuls | 2010 |
Valproic acid: long-term effects on children exposed in utero.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Contraindications; Dose | 2009 |
In ovo nanoinjection of triclosan, diclofenac and carbamazepine affects embryonic development of medaka fish (Oryzias latipes).
Topics: Animals; Carbamazepine; Diclofenac; Environmental Monitoring; Female; Injections; Maternal-Fetal Exc | 2010 |
[A case report of monitoring on carbamazepine in breast feeding woman].
Topics: Adult; Breast Feeding; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Epileps | 2010 |
Effects of breastfeeding in children of women taking antiepileptic drugs.
Topics: Adult; Anticonvulsants; Breast Feeding; Carbamazepine; Child, Preschool; Cognition; Epilepsy; Female | 2010 |
Carbamazepine in pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newbo | 2010 |
Value of the small cohort study including a physical examination for minor structural defects in identifying new human teratogens.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Antidepressive Agents; Arthritis, Rheumatoid; Carbamaz | 2011 |
Drug monitoring of lamotrigine and oxcarbazepine combination during pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Monitoring; Drug Thera | 2010 |
Carbamazepine in pregnancy: Levetiracetam and lamotrigine are better options.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Contraindications; Epilepsy; Female; Hu | 2011 |
Neurodevelopment of children exposed in utero to lamotrigine, sodium valproate and carbamazepine.
Topics: Anticonvulsants; Carbamazepine; Case-Control Studies; Child, Preschool; Developmental Disabilities; | 2011 |
Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epile | 2011 |
Fetal effects of anticonvulsant polytherapies: different risks from different drug combinations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Canada; Carbamazepine; Cohort Studies; Drug Therapy, C | 2011 |
Antiepileptic drug use during pregnancy: perinatal outcomes.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Cohort Studies; Drug | 2011 |
Influencing clinical practice regarding the use of antiepileptic medications during pregnancy: modeling the potential impact on the prevalences of spina bifida and cleft palate in the United States.
Topics: Anticonvulsants; Carbamazepine; Cleft Palate; Female; Humans; Pregnancy; Pregnancy Complications; Pr | 2011 |
Use of antiepileptic medications in pregnancy in relation to risks of birth defects.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Hu | 2011 |
The effect of valproic acid and oxcarbazepine on the distribution of adhesion molecules in embryo implantation.
Topics: Animals; Anticonvulsants; Carbamazepine; Cell Adhesion Molecules; Collagen Type IV; Embryo Implantat | 2012 |
Perioperative management of a parturient with hyponatraemia due to carbamazepine therapy.
Topics: Adult; Anesthesia, Obstetrical; Anticonvulsants; Carbamazepine; Cesarean Section; Female; Humans; Hy | 2012 |
Neonatal seizures associated with a severe neonatal myoclonus like dyskinesia due to a familial KCNQ2 gene mutation.
Topics: Adult; Anticonvulsants; Carbamazepine; Developmental Disabilities; Dyskinesias; Electroencephalograp | 2012 |
Is conventional hemodialysis enough to manage carbamazepine intoxication?.
Topics: Adult; Anticonvulsants; Carbamazepine; Charcoal; Drug Overdose; Female; Humans; Pregnancy; Renal Dia | 2012 |
Is carbamazepine safe to take during pregnancy?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Neural Tube D | 2012 |
Multiple fetal anomalies in association with topiramate and oxcarbezepine treatment.
Topics: Abnormalities, Multiple; Adult; Anticonvulsants; Carbamazepine; Female; Fetus; Fructose; Humans; Oxc | 2012 |
Prenatal antiepileptic exposure associates with neonatal DNA methylation differences.
Topics: Anticonvulsants; Carbamazepine; CpG Islands; Depressive Disorder, Major; DNA Methylation; Drug Evalu | 2012 |
Economic evaluation of anti-epileptic drug therapies with specific focus on teratogenic outcomes.
Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Cost-Benefit Analysis; Epil | 2012 |
A case of fetal carbamazepine syndrome with right hemihypoplasia of the entire body.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Bone and Bones; Carbamazepine; Congenital Abnormalitie | 2012 |
Carbamazepine use in pregnancy and coincidental thalidomide-like phocomelia in a newborn.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Ectromelia; Female; Humans; Infant, New | 2012 |
Is early hemodialysis indicated in the treatment of carbamazepine intoxication?
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Pregnancy; Renal Dialysis | 2012 |
Severe consequences of carbamazepine exposure in utero.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant | 2011 |
Calcitonin for phantom limb pain in a pregnant woman.
Topics: Adult; Amines; Amputation, Surgical; Analgesics, Opioid; Calcitonin; Carbamazepine; Cyclohexanecarbo | 2012 |
The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Child Development Disorders, Per | 2013 |
Effects of prenatal exposure to carbamazepine on brainstem auditory evoked potentials in infants of epileptic mothers.
Topics: Adult; Anticonvulsants; Carbamazepine; Embryonic and Fetal Development; Epilepsy; Evoked Potentials, | 2002 |
Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Carbamazepine; Disea | 2002 |
Chondrodysplasia punctata (CDP) with features of the tibia-metacarpal type and maternal phenytoin treatment during pregnancy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Chondrodysplasia Punctata; Craniofacial Abnormalit | 2002 |
Comment on antiepileptics and antipsychotics.
Topics: Animals; Anticonvulsants; Antipsychotic Agents; Carbamazepine; Female; Folic Acid; Hematinics; Human | 2002 |
Major malformations in offspring of women with epilepsy.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Comorbidity; Educational Status; | 2003 |
A pregnant woman with newly diagnosed epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Tolerance; Epilepsies, Partial; Epilepsy, Generalized; F | 2003 |
The Australian registry of anti-epileptic drugs in pregnancy: experience after 30 months.
Topics: Abortion, Induced; Anticonvulsants; Australia; Carbamazepine; Cohort Studies; Congenital Abnormaliti | 2003 |
Anticonvulsant hypersensitivity reaction in pregnancy.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Female; Humans; Meningeal Neoplasms; Meningio | 2003 |
Major malformations in offspring of women with epilepsy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Logistic Mode | 2003 |
Normal intelligence in children with prenatal exposure to carbamazepine.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy; | 2004 |
Chronic prenatal exposure to carbamazepine and perinatal outcomes of C3H/He mice.
Topics: Animals; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Female; Mice | 2004 |
Chronic prenatal exposure to carbamazepine and behavior effects on mice offspring.
Topics: Animals; Anticonvulsants; Arousal; Carbamazepine; Cognition; Female; Mice; Mice, Inbred C3H; Motivat | 2004 |
Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study.
Topics: Abnormalities, Multiple; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fetal Diseases; Hu | 2004 |
Oxcarbazepine in pregnancy: clinical experience in Argentina.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Argentina; Carbamazepine; Drug Therapy, Combination; E | 2004 |
Navigating toward fetal and maternal health: the challenge of treating epilepsy in pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Child; Cohort Studies; Confoundi | 2004 |
Longer term outcome of children born to mothers with epilepsy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Fema | 2004 |
The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cognition Disorders; Face; Facie | 2005 |
Mega-dose carbamazepine complicating third trimester of pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Cardiotocography; Diagnosis, Differential; Female; Fetal Bloo | 2005 |
Failure of Implanon contraception in a patient taking carbamazepin for epilepsia.
Topics: Adult; Anticonvulsants; Carbamazepine; Contraceptive Agents, Female; Desogestrel; Drug Interactions; | 2006 |
Dysmorphic features: an important clue to the diagnosis and severity of fetal anticonvulsant syndromes.
Topics: Abnormalities, Drug-Induced; Adolescent; Anthropometry; Anticonvulsants; Carbamazepine; Child; Child | 2006 |
Seizure control and treatment in pregnancy: observations from the EURAP epilepsy pregnancy registry.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Femal | 2006 |
Changes in the disposition of oxcarbazepine and its metabolites during pregnancy and the puerperium.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dose-Response Relations | 2006 |
[Management of malignant gliomas diagnosed during pregnancy].
Topics: Abortion, Therapeutic; Adrenal Cortex Hormones; Adult; Algorithms; Anesthesia, General; Antineoplast | 2006 |
[Muscle cramp--what is at the bottom of it? Only a little strained or seriously sick?].
Topics: Age Factors; Aged; Amines; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Citric Acid; Cy | 2006 |
Woman on the verge.
Topics: Antimanic Agents; Bipolar Disorder; Carbamazepine; Female; Humans; Physician-Patient Relations; Preg | 2006 |
A case of fetal anticonvulsant syndrome with severe bilateral upper limb defect.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fetal Diseases | 2006 |
Antiepileptic drug use and birth rate in patients with epilepsy--a population-based cohort study in Finland.
Topics: Adolescent; Adult; Anticonvulsants; Birth Rate; Carbamazepine; Cohort Studies; Epilepsy; Female; Fin | 2006 |
Treatment with oxcarbazepine during pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy, Complex Partial; Female; Humans; Oxcarbazepine; Pre | 2006 |
Women on the verge.
Topics: Adult; Bipolar Disorder; Carbamazepine; Decision Making; Female; Humans; Pregnancy; Pregnancy Compli | 2006 |
The effects of valproate exposure in utero on behavior and the need for educational support in school-aged children.
Topics: Anticonvulsants; Carbamazepine; Child; Cognition; Education, Special; Epilepsy; Female; Humans; Ment | 2006 |
Oxcarbazepine concentrations during pregnancy: a retrospective study in patients with epilepsy.
Topics: Analysis of Variance; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dose-Res | 2006 |
Intracranial arteriovenous malformation with maternal carbamazepine use.
Topics: Adult; Carbamazepine; Cerebral Angiography; Fatal Outcome; Female; Humans; Infant; Intracranial Arte | 2007 |
Unilateral multicystic dysplastic kidney in infants exposed to antiepileptic drugs during pregnancy.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Follow-Up Studies; Humans; Infant, Newborn; Matern | 2007 |
Drug treatment during pregnancy and isolated orofacial clefts in hungary.
Topics: Abnormalities, Drug-Induced; Adrenergic beta-Antagonists; Amoxicillin; Anti-Bacterial Agents; Antico | 2007 |
A survey of antiepileptic prescribing to women of childbearing potential in psychiatry.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Prescriptions; England; Epilepsy; Female; Ho | 2007 |
Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Female; Fetus | 2007 |
Transposition of the great arteries in a newborn whose mother was treated with carbamazepine during pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Diagnosis, Differential; Female; Humans; Infant, Newborn; Mal | 2007 |
Oxcarbazepine treatment during breast-feeding: a case report.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Breast Feeding; Carbamazepine; Child, Preschool; Depressiv | 2007 |
Anticonvulsant drug therapy in human pregnancy: effects on serum concentrations of vitamin D metabolites in maternal and cord blood.
Topics: 24,25-Dihydroxyvitamin D 3; Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Calcifediol; C | 1984 |
Fetal head growth retardation associated with maternal antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Female; Fetal Growth Retardation; Follow- | 1981 |
False-negative pregnancy test women taking carbamazepine.
Topics: Carbamazepine; False Negative Reactions; Female; Humans; Pregnancy; Pregnancy Tests | 1982 |
Pharmacokinetics of antiepileptic drugs.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool | 1983 |
Antiepileptic drugs and teratogenesis. How should patients, doctors and health authorities be counselled?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newbo | 1983 |
Serum folate concentrations during pregnancy in women with epilepsy: relation to antiepileptic drug concentrations, number of seizures, and fetal outcome.
Topics: Carbamazepine; Congenital Abnormalities; Epilepsy; Female; Fetal Death; Folic Acid; Humans; Phenobar | 1983 |
[Pharmacotherapy of epilepsy--current problems and controversies].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, | 1983 |
Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy.
Topics: Abnormalities, Drug-Induced; Arousal; Benzodiazepinones; Carbamazepine; Chemical and Drug Induced Li | 1983 |
Enzyme induction in neonates after fetal exposure to antiepileptic drugs.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Anticonvulsants; Breath Tests; Carbamazepine; Carbon Radiois | 1983 |
Teratogenic effects of dosage levels and time of administration of carbamazepine, sodium valproate, and diphenylhydantoin on craniofacial development in the CD-1 mouse fetus.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Dr | 1984 |
Obturator neuropathy after forceps delivery.
Topics: Adult; Carbamazepine; Delivery, Obstetric; Female; Humans; Hyperesthesia; Lidocaine; Methylprednisol | 1984 |
[Treatment of pregnant epileptics with carbamazepine. Preliminary report].
Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Epilepsy; Female; Humans; Pregnancy; Pregnancy Co | 1984 |
Psychomotor status--a female case in the 34th week of pregnancy.
Topics: Adult; Carbamazepine; Clonazepam; Drugs, Chinese Herbal; Electroencephalography; Epilepsy; Epilepsy, | 1983 |
Cranial nerve agenesis in a fetus exposed to carbamazepine.
Topics: Adult; Carbamazepine; Facial Nerve; Female; Humans; Hypoglossal Nerve; Infant, Newborn; Pregnancy | 1983 |
Carbamazepine, seizure disorders, and pregnancy.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Epilepsy; Female; Humans; Pregnancy; Pregnancy Complicat | 1983 |
Comparative study on the teratogenicity of some antiepileptics in the rat.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Carbamazepine; Ethos | 1983 |
Carbamazepine and carbamazepine-10,11- epoxide during pregnancy and postnatal period in epileptic mother and their nursed infants: pharmacokinetics and clinical effects.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Female; | 1983 |
Teratogenicity of antiepileptic drug combinations with special emphasis on epoxidation (of carbamazepine).
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Therapy, | 1984 |
Protein binding of carbamazepine and its epoxide in maternal and fetal plasma at delivery: comparison to other anticonvulsants.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Fatty Acids, | 1984 |
Teratogenic effects of anticonvulsants.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Cleft Palate; Eyelid Diseases; | 1981 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Female; | 1981 |
Recent advances in the treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Huma | 1980 |
Sodium valproate: monotherapy and polytherapy.
Topics: Adolescent; Adult; Carbamazepine; Drug Therapy, Combination; Epilepsies, Myoclonic; Epilepsies, Part | 1982 |
[Valproate and congenital abnormalities].
Topics: Abnormalities, Drug-Induced; Carbamazepine; Female; Humans; Pregnancy; Valproic Acid | 1982 |
Alcohol, other drugs and the fetus.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Dextropropoxyphene; Diazepam; Drug Synergism; Female; Fe | 1982 |
Carbamazepine. Pharmacology and clinical uses.
Topics: Adult; Alcohol Withdrawal Delirium; Arrhythmias, Cardiac; Behavior; Carbamazepine; Child; Diabetes I | 1981 |
Preliminary study of the effects of carbamazepine on congenital orofacial defects in offspring of A/J mice.
Topics: Abnormalities, Drug-Induced; Animals; Carbamazepine; Cleft Lip; Cleft Palate; Female; Maternal-Fetal | 1982 |
[Generalized side effects with the use of carbamazepine].
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Lympha | 1995 |
Neurodevelopment of children exposed in utero to phenytoin and carbamazepine monotherapy.
Topics: Carbamazepine; Case-Control Studies; Child; Cognition; Developmental Disabilities; Female; Humans; I | 1994 |
Neurodevelopment after in utero exposure to phenytoin and carbamazepine.
Topics: Carbamazepine; Child; Developmental Disabilities; Female; Humans; Phenytoin; Pregnancy; Prenatal Exp | 1994 |
Neurodevelopment after in utero exposure to phenytoin and carbamazepine.
Topics: Carbamazepine; Child; Developmental Disabilities; Female; Humans; Phenytoin; Pregnancy; Prenatal Exp | 1994 |
Red cell folate levels in pregnant epileptic women.
Topics: Adult; Carbamazepine; Epilepsy; Erythrocytes; Female; Folic Acid; Follow-Up Studies; Humans; Phenyto | 1995 |
Carbamazepine and its metabolites in human perfused placenta and in maternal and cord blood.
Topics: Antipyrine; Biological Transport; Blood; Carbamazepine; Chromatography, Gas; Chromatography, High Pr | 1995 |
Metabolism of carbamazepine and co-administered anticonvulsants during pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenytoi | 1995 |
Diabetes insipidus.
Topics: Benzothiadiazines; Carbamazepine; Chlorpropamide; Clofibrate; Diabetes Insipidus; Diuretics; Female; | 1994 |
Lithium: the present and the future.
Topics: Acute Disease; Bipolar Disorder; Carbamazepine; Depressive Disorder; Drug Interactions; Female; Huma | 1995 |
Prevention of neural tube defects.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Female; Folic Acid; Humans; Neural Tube Defects; Pregnan | 1994 |
Radial ray aplasia in utero: a prenatal finding associated with valproic acid exposure.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Carbamazepine; Epilepsy, Absence; Female; Huma | 1994 |
Pregnancy, epilepsy, management and outcome: a 10-year perspective.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Birth Weight; Carbamazepine; Cohort Studies; Drug Ther | 1993 |
[Diabetes insipidus during pregnancy: apropos of 2 case reports].
Topics: Adult; Carbamazepine; Deamino Arginine Vasopressin; Diabetes Insipidus; Female; Humans; Infant, Newb | 1994 |
Teratogenicity of antiepileptic drugs and drug specific malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug | 1993 |
Sporadic Pick's disease in a 28-year-old woman.
Topics: Adult; Atrophy; Carbamazepine; Dementia; Electroconvulsive Therapy; Female; Frontal Lobe; Haloperido | 1993 |
Practices of epilepsy during pregnancy: a survey of Canadian neurologists.
Topics: Anticonvulsants; Canada; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Neurolo | 1993 |
The 10,11-epoxide-10,11-diol pathway of carbamazepine in early pregnancy in maternal serum, urine, and amniotic fluid: effect of dose, comedication, and relation to outcome of pregnancy.
Topics: Abnormalities, Drug-Induced; Amniotic Fluid; Carbamazepine; Cohort Studies; Dose-Response Relationsh | 1993 |
Paralytic ileus in a fetus-neonate after maternal intake of benzodiazepine.
Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Epilepsy; Female; Fetal Diseases; Humans; Infant, | 1995 |
Infant monkey hyperexcitability after prenatal exposure to antiepileptic compounds.
Topics: Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Carbamazepine; Dioxolanes; Disease Mod | 1996 |
Fetal malformations in an epileptic pregnant woman treated with carbamazepine.
Topics: Abnormalities, Drug-Induced; Abortion, Eugenic; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Fem | 1996 |
Improved detection and determination of carbamazepine and oxcarbazepine and their metabolites by high-performance liquid chromatography.
Topics: Anticonvulsants; Calibration; Carbamazepine; Chromatography, High Pressure Liquid; Female; Humans; M | 1995 |
Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Female; Mice; Mice, Inbred Strains; Oxcarbazepine; Pregnanc | 1996 |
[Epilepsy and pregnancy. Prospective study of 100 cases].
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Birth Weight; Carbamazepine; Epilepsy; Female; Hum | 1996 |
Lamotrigine and pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Femal | 1996 |
Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy.
Topics: Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Child Development; Child, Preschool; Cr | 1996 |
Pharmacokinetics of oxcarbazepine and carbamazepine in human placenta.
Topics: Anticonvulsants; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Epilepsy; Fe | 1997 |
[Pharmacokinetic variations in anticonvulsants in Mexican epileptic women during different stages of the postpartum period].
Topics: Animals; Anticonvulsants; Carbamazepine; Cricetinae; Epilepsy; Female; Humans; Milk, Human; Phenytoi | 1997 |
[Carbamazepine and vigabatrin in epileptic pregnant woman and side effects in the newborn infant].
Topics: Alkaline Phosphatase; Anticonvulsants; Carbamazepine; Chlorine; Drug Therapy, Combination; Epilepsy; | 1997 |
Fluoxetine and carbamazepine concentrations in a nursing mother/infant pair.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Breast Feeding; Carbamazepine; Female; Fluoxetine; Humans; | 1998 |
Teratogenic effects of antiepileptic drugs: what do we advise patients?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Patient Advoc | 1997 |
Pharmacologically induced embryonic dysrhythmia and episodes of hypoxia followed by reoxygenation: a common teratogenic mechanism for antiepileptic drugs?
Topics: Abnormalities, Drug-Induced; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; | 1998 |
Congenital neuroblastoma in a boy born to a woman with bipolar disorder treated with carbamazepine during pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenal Gland Neoplasms; Adult; Anticonvulsants; Bipolar Disorder; Carb | 1998 |
Eye malformations associated with treatment with carbamazepine during pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Coloboma; Eye Abnormalities; Female; Fe | 1998 |
Outcome of pregnancies in epileptic women: a study in Saudi Arabia.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Middle Aged; Pregnancy; | 1999 |
Congenital unilateral fusion of the maxilla and mandible.
Topics: Anticonvulsants; Branchial Region; Carbamazepine; Dose-Response Relationship, Drug; Fatal Outcome; F | 1999 |
[Should folic acid be given to women treated with valproic acid and/or carbamazepine? Folic acid and pregnancy in epilepsy].
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Folic Acid; Humans; Neural Tube Defects; Pregnancy | 1999 |
Malformations in offspring of women with epilepsy: a prospective study.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Comorbidity; Congenital Abnormalities; | 1999 |
Radial microbrain form of micrencephaly: possible association with carbamazepine.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Male; Microcephaly; Pregnancy; Preg | 1999 |
Epileptogenic activity of folic acid.
Topics: Anticonvulsants; Carbamazepine; Dietary Supplements; Epilepsy; Female; Folic Acid; Humans; Lupus Ery | 2000 |
A clinical study of 57 children with fetal anticonvulsant syndromes.
Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Ep | 2000 |
Body dimensions of infants exposed to antiepileptic drugs in utero: observations spanning 25 years.
Topics: Anticonvulsants; Birth Weight; Body Height; Carbamazepine; Drug Therapy, Combination; Embryonic and | 2000 |
Neonatal hypoglycaemia and withdrawal symptoms after exposure in utero to valproate.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Hypoglycemia; I | 2000 |
Population based, prospective study of the care of women with epilepsy in pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fetal Death; Guidelin | 2000 |
Neurotoxic/neuroprotective profile of carbamazepine, oxcarbazepine and two new putative antiepileptic drugs, BIA 2-093 and BIA 2-024.
Topics: Animals; Anticonvulsants; Carbamazepine; Caspase 3; Caspases; Cells, Cultured; Dibenzazepines; Excit | 2000 |
The teratogenicity of anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Case-Control Studies; Congenital Abnorm | 2001 |
Evidence based information on drug use during pregnancy: a survey of community pharmacists in three countries.
Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Antitrichomonal Agents; Canada; Ca | 2001 |
Selection bias in Teratology Information Service pregnancy outcome studies.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; California; Carbamazepine; Drug Information Ser | 2001 |
Is carbamazepine teratogenic? A prospective controlled study of 210 pregnancies.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Pregna | 2001 |
[Oxcarbazepine].
Topics: Adult; Animals; Anticonvulsants; Carbamazepine; Child, Preschool; Clinical Trials as Topic; Drug Int | 2001 |
Antenatal carbamazepine use associated with d-TGA and ASD.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Heart Septal Defects, Atrial; Humans; Infan | 2002 |
Transplacental passage of oxcarbazepine and its metabolites in vivo.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fetal Blood; Humans; Maternal-Fetal Exchang | 2001 |
Neonatal cholestatic hepatitis from carbamazepine exposure during pregnancy and breast feeding.
Topics: Breast Feeding; Carbamazepine; Chemical and Drug Induced Liver Injury; Cholestasis; Epilepsy; Female | 2002 |
Loss prevention case of the month. Knowledge deficit: all of us have them.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy, Tonic-Clonic; Fatal Outcome; Female; Humans; Malpra | 2002 |
Placental transfer of carbamazepine in the rat.
Topics: Animals; Brain; Carbamazepine; Female; Fetus; Gestational Age; Kinetics; Maternal-Fetal Exchange; Mo | 1975 |
Letter: Carbamazepine and mother's milk.
Topics: Carbamazepine; Female; Humans; Infant, Newborn; Milk, Human; Pregnancy | 1975 |
The medical treatment of epilepsy: antiepileptic drug interactions and teratogenicity.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Calcium; Carbamazepine; Child; Dicumarol; Digit | 1979 |
[Drug therapy of epilepsy].
Topics: Age Factors; Anticonvulsants; Barbiturates; Benzodiazepines; Bromides; Carbamazepine; Chlormethiazol | 1977 |
Long-term use of the major anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximi | 1978 |
Anticonvulsant therapy. Approaches to some common clinical problems.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Eth | 1979 |
[Significance of pharmacogenic liver reactions for metabolism of endogenous and exogenous substances].
Topics: Carbamazepine; Diazepam; Drug-Related Side Effects and Adverse Reactions; Female; Fenoterol; Humans; | 1979 |
Phenytoin and carbamazepine in production of cleft palates in mice. Comparison of teratogenic effects.
Topics: Animals; Carbamazepine; Cleft Palate; Dose-Response Relationship, Drug; Female; Mice; Phenytoin; Pre | 1979 |
Carbamazepine in two pregnancies.
Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Epilepsy; Female; Fetal Death; Humans; Maternal-F | 1979 |
Carbamazepine: placental transport, tissue concentrations in foetus and newborn, and level in milk.
Topics: Adolescent; Adult; Carbamazepine; Female; Fetus; Humans; Infant; Infant, Newborn; Male; Maternal-Fet | 1977 |
Kinetics of drug interactions in the treatment of epilepsy.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethanol; Female; Humans; Kinet | 1978 |
[Neonatal abstinence syndrome in children whose mothers were treated for epilepsy during pregnancy].
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newborn; Infant, Newborn, D | 1978 |
Carbamazepine levels in pregnancy and lactation.
Topics: Adult; Carbamazepine; Epilepsy, Temporal Lobe; Female; Fetal Blood; Fetus; Humans; Lactation; Milk, | 1979 |
Seizures in adolescents.
Topics: Adolescent; Anticonvulsants; Automobile Driving; Benzodiazepines; Carbamazepine; Diagnosis, Differen | 1975 |
A comparison of the teratogenic activity of the antiepileptic drugs carbamazepine, clonazepam, ethosuximide, phenobarbital, phenytoin, and primidone in mice.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Fema | 1977 |
[Antiepileptics, pregnancy and breast feeding].
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Breast Feeding; Carbamazepine; Epilepsy; Female; Hum | 1976 |
Carbamazepine pharmacokinetics in young, adult and pregnant rats. Relation to pharmacological effects.
Topics: Aging; Animals; Carbamazepine; Electroshock; Female; Kinetics; Male; Maternal-Fetal Exchange; Pentob | 1976 |
Effect of 2 br-alpha-ergocryptin (CB 154) on serum prolactin and the clinical picture in a case of progressive gigantomastia in pregnancy.
Topics: Adult; Breast Diseases; Bromocriptine; Carbamazepine; Diazepam; Epilepsy, Temporal Lobe; Ergolines; | 1976 |
Drug stimulated biotransformation of hormonal steroid contraceptives: clinical implications.
Topics: Ampicillin; Biotransformation; Carbamazepine; Contraceptives, Oral; Contraceptives, Oral, Hormonal; | 1976 |
Absorption and distribution of antiepileptic drugs.
Topics: Administration, Oral; Animals; Anticonvulsants; Capsules; Carbamazepine; Female; Humans; Injections, | 1975 |
Carbamazepine: absorption, distribution, and excretion.
Topics: Administration, Oral; Animals; Carbamazepine; Epilepsy; Female; Humans; Injections, Intravenous; Int | 1975 |
Serum carbamazepine concentration and clinical control.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Male; Pregnancy; Seizures; Substance-Related Disorde | 1975 |
Disposition of placentally transferred carbamazepine (Tegretol) in the newborn.
Topics: Carbamazepine; Epilepsy; Female; Half-Life; Humans; Infant, Newborn; Kinetics; Maternal-Fetal Exchan | 1975 |
Salivary concentrations of antiepileptic drugs, oestradiol and progesterone throughout pregnancy in epileptic women.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Estradiol; Female; Humans; Osmolar Concentration; P | 1992 |
Transient hepatic dysfunction in an infant of an epileptic mother treated with carbamazepine during pregnancy and breastfeeding.
Topics: Adult; Breast Feeding; Carbamazepine; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Infant, N | 1992 |
The use of carbamazepine for episodic violence in multiple personality disorder and dissociative disorder not otherwise specified: two additional cases.
Topics: Adolescent; Adult; Anger; Carbamazepine; Dissociative Disorders; Dissociative Identity Disorder; Dos | 1992 |
Spectrum of neural-tube defects in 34 infants prenatally exposed to antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, | 1992 |
Antiepileptic drug disposition during pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Valproic | 1992 |
Antiepileptics and the development of congenital anomalies.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Apgar Score; Birth Weight; Carbamazepine; Epilepsy; Fe | 1992 |
Antiepileptic drugs and teratogenesis in two consecutive cohorts: changes in prescription policy paralleled by changes in pattern of malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Drug Prescriptions; Epi | 1992 |
Course of pregnancy and fetal outcome following maternal exposure to carbamazepine and phenytoin: a prospective study.
Topics: Abnormalities, Drug-Induced; Analysis of Variance; Carbamazepine; Epilepsy; Female; Humans; Phenytoi | 1992 |
Loss of seizure control associated with generic substitution of carbamazepine.
Topics: Adolescent; Adult; Carbamazepine; Drugs, Generic; Female; Humans; Male; Pregnancy; Pregnancy Complic | 1992 |
Teratogenesis with carbamazepine.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Epilepsy; Female; Humans; Pregnancy; Pregnancy Complicat | 1991 |
Carbamazepine blocks NMDA-activated currents in cultured spinal cord neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Carbamazepine; Cells, Cultured; Dizocilpine Malea | 1990 |
[The course of pregnancy and teratogenicity of antiepileptic agents in 66 patients with epilepsy].
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combin | 1991 |
Sodium valproate, carbamazepine and spina bifida.
Topics: Carbamazepine; Female; Humans; Pregnancy; Spinal Dysraphism; Valproic Acid | 1991 |
Spina bifida in infants of women taking carbamazepine.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newborn; Pregnancy; Pregnancy Comp | 1991 |
[Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital].
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Birth Weight; Carbamazepine; Embryonic and Feta | 1991 |
Dopa-responsive dystonia: long-term treatment response and prognosis.
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Depression; Dihydroxyphenylalanine; Disab | 1991 |
Carbamazepine and spina bifida.
Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Female; Humans; Infant, Newborn; Pregnancy; Spina | 1991 |
Antiepileptic medication in pregnancy: late effects on the children's central nervous system development.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Central Nervous System; Child; Child De | 1991 |
Congenital rib anomalies in a fetus exposed to carbamazepine.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Female; Fetus; Humans; Infant, Newborn; Maternal-Fetal E | 1991 |
Teratogenic effect of carbamazepine.
Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Epilepsy; Facial Bones; Female; Humans; Infant, N | 1991 |
On the use of anticonvulsants for manic depression during pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Bipolar Disorder; Carbamazepine; Female; Humans; Infan | 1990 |
Possible roles for frequent salivary antiepileptic drug monitoring in the management of epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Menstrua | 1990 |
[Therapeutic drug monitoring of carbamazepine].
Topics: Adult; Age Factors; Biological Availability; Carbamazepine; Child; Child, Preschool; Female; Humans; | 1990 |
Transient cholestatic hepatitis in a neonate associated with carbamazepine exposure during pregnancy and breast-feeding.
Topics: Breast Feeding; Carbamazepine; Chemical and Drug Induced Liver Injury; Epilepsy; Female; Humans; Inf | 1990 |
Protein binding of antiepileptic drugs during pregnancy, labor, and puerperium.
Topics: Adult; Anticonvulsants; Carbamazepine; Fatty Acids, Nonesterified; Female; Fetal Blood; Humans; Labo | 1990 |
Potassium currents in rat cortical neurons in culture are enhanced by the antiepileptic drug carbamazepine.
Topics: 4-Aminopyridine; Animals; Cadmium; Calcium; Carbamazepine; Cells, Cultured; Cerebral Cortex; Ethanol | 1990 |
Head circumference in children of epileptic mothers: contributions of drug exposure and genetic background.
Topics: Adult; Anticonvulsants; Carbamazepine; Child, Preschool; Epilepsy; Female; Humans; Intelligence Test | 1990 |
Pharmacokinetics of anticonvulsants in pregnancy: alterations in plasma protein binding.
Topics: Adult; Anticonvulsants; Blood Proteins; Carbamazepine; Epilepsy; Female; Humans; Maternal-Fetal Exch | 1990 |
Epilepsy in women of childbearing age.
Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Child; Epilepsy; Female; Humans; Pregnancy; Pregn | 1989 |
Epilepsy in women of childbearing age.
Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Epilepsy; Female; Humans; Pregnancy; Pregnancy Co | 1989 |
Pattern of malformations in the children of women treated with carbamazepine during pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Female; Fetu | 1989 |
Value of saliva anticonvulsant monitoring in pregnancy and the newborn.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Monitoring, Physiologic; Phenobarbi | 1989 |
Pregnancy and epilepsy.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Estrogens; Female; Hum | 1989 |
Interactions between carbamazepine and birth control pills.
Topics: Adult; Bipolar Disorder; Carbamazepine; Contraceptives, Oral; Drug Interactions; Female; Humans; Pre | 1989 |
Teratogenic effects of carbamazepine.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Epilepsy; Female; Fetus; Humans; Pregnancy; Pregnancy Co | 1989 |
Valpromide/carbamazepine and risk of teratogenicity.
Topics: Abnormalities, Drug-Induced; Animals; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Hu | 1985 |
Failure of epoxide formation to influence carbamazepine-induced teratogenesis in a mouse model.
Topics: Animals; Carbamazepine; Female; Fetal Blood; Fetal Growth Retardation; Mice; Mice, Inbred Strains; P | 1986 |
Relationship between ossification and body weight of the CD-1 mouse fetus exposed in utero to anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Female; Fetu | 1986 |
Anticonvulsant drugs in monotherapy. Effect on the fetus.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fe | 1987 |
Clinical performance of a levonorgestrel-releasing intracervical contraceptive device during the first year of use.
Topics: Adult; Carbamazepine; Cervix Uteri; Contraceptive Devices, Female; Female; Humans; Levonorgestrel; N | 1987 |
The role of ultrasound in the early diagnosis of fetal structural defects following maternal anticonvulsant therapy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Diazepam; Female; Humans; Infant, Newbo | 1988 |
Restless leg syndrome in pregnancy.
Topics: Carbamazepine; Female; Humans; Pregnancy; Pregnancy Complications; Restless Legs Syndrome | 1988 |
Congenital abnormalities in two sibs exposed to valproic acid in utero.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Infan | 1988 |
Prescribing lithium for pregnant women.
Topics: Adult; Bipolar Disorder; Carbamazepine; Female; Gestational Age; Haloperidol; Humans; Infant, Newbor | 1988 |
Carbamazepine, clonazepam use during pregnancy.
Topics: Abnormalities, Drug-Induced; Benzodiazepinones; Carbamazepine; Clonazepam; Epilepsy; Female; Humans; | 1986 |
Carbamazepine in pregnancy.
Topics: Carbamazepine; Female; Humans; Pregnancy; Pregnancy Complications; Psychotic Disorders | 1986 |
The effects of long-term anticonvulsant drug therapy on vitamin D metabolites and mineral homeostasis in pregnant epileptic women and their newborns.
Topics: Adolescent; Adult; Anticonvulsants; Calcifediol; Calcitriol; Carbamazepine; Dihydroxycholecalciferol | 1985 |
Effects of pregnancy on seizure threshold and the disposition and efficacy of antiepileptic drugs in the mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Electroshock; Female; Kinetics; Mice; Phenobarbital; Phenyt | 1985 |
Effects of pregnancy on antiepileptic drug utilization.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Epilepsy; Female; Humans; Kinetics; Metabol | 1985 |
Persistent right umbilical vein--case report and review of literature.
Topics: Abnormalities, Multiple; Carbamazepine; Ectromelia; Epilepsy; Female; Heart Septal Defects, Atrial; | 1986 |
Seizure disorders and pregnancy.
Topics: Carbamazepine; Female; Humans; Phenytoin; Pregnancy; Pregnancy Complications; Seizures | 1986 |
[Clinical pharmacology of carbamazepine--a comparison with phenytoin].
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Female; Humans; Male; Phenytoin; Pregnancy | 1985 |
Finger- and toenail hypoplasia after carbamazepine monotherapy in late pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Epilepsy; Female; Humans; Infant, Newborn; Nails, | 1985 |
Carbamazepine protein binding and disposition in pregnancy.
Topics: Adult; Blood Proteins; Carbamazepine; Female; Humans; Maternal-Fetal Exchange; Metabolic Clearance R | 1985 |
Letter: Digital hypoplasia and anticonvulsants during pregnancy.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Diazepam; Female; Fingers; Maternal-Fetal Exchange; Ph | 1974 |
[Treatment of epilepsy with carbamazepine].
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Child, Preschool; Epilepsy, Tonic-Clonic; Female; Hum | 1972 |
Carbamazepine (tegretol)--trigeminal neuralgia and other uses.
Topics: Carbamazepine; Epilepsy; Facial Neuralgia; Female; Glossopharyngeal Nerve; Humans; Multiple Sclerosi | 1973 |
The teratological effects of anticonvulsants and the effects on pregnancy and birth.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cleft Lip; Cleft Palate; Cyclohe | 1973 |
[Letter: Teratogenic hazards in antiepileptic therapy].
Topics: Abnormalities, Drug-Induced; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Preg | 1974 |
The side effects of carbamazepine therapy.
Topics: Ataxia; Carbamazepine; Depression; Dibenzazepines; Female; Humans; Leukocyte Count; Male; Middle Age | 1968 |
[Pharmacology of carbamazepine].
Topics: Animals; Carbamazepine; Cats; Dibenzazepines; Female; Male; Mice; Pregnancy; Pregnancy, Animal; Rabb | 1967 |
[Congenital adrenogenital syndrome. A case observed in connection with therapy with Tegretol in pregnancy].
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Carbamazepine; Dibenzazepines; Female; Humans; Infant, | 1969 |