carbamazepine has been researched along with Porphyrias in 11 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A case of non-hereditary acute porphyria, similar to acute intermittent porphyria, following treatment of epilepsy with carbamazepine is reported." | 7.66 | Carbamazepine-induced non-hereditary acute porphyria. ( Brodie, MJ; Goldberg, A; Macphee, GJ; Moore, MR; Philip, MF; Rapeport, WG; Thompson, GG; Yeung Laiwah, AA, 1983) |
| "The effects of acute carbamazepine (CBZ) administration on haem metabolism in rat liver were examined in relation to the mechanism by which it exacerbates hepatic porphyrias." | 3.68 | Effects of acute carbamazepine administration on haem metabolism in rat liver. ( Badawy, AA; Morgan, CJ, 1992) |
| " A case of non-hereditary acute porphyria, similar to acute intermittent porphyria, following treatment of epilepsy with carbamazepine is reported." | 3.66 | Carbamazepine-induced non-hereditary acute porphyria. ( Brodie, MJ; Goldberg, A; Macphee, GJ; Moore, MR; Philip, MF; Rapeport, WG; Thompson, GG; Yeung Laiwah, AA, 1983) |
| "The porphyrias are a metabolic disorders of heme biosynthesis characterized by the excessive production and excretion of porphyrins and porphyrin precursors." | 2.39 | [Porphyrias and drugs]. ( Karasawa, M; Murakami, H; Tamura, J, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yeung Laiwah, AA | 1 |
| Rapeport, WG | 1 |
| Thompson, GG | 1 |
| Macphee, GJ | 1 |
| Philip, MF | 1 |
| Moore, MR | 1 |
| Brodie, MJ | 2 |
| Goldberg, A | 2 |
| Shanley, BC | 1 |
| Laiwah, AC | 1 |
| Rideout, JM | 1 |
| Wright, DJ | 1 |
| Lim, CK | 1 |
| Rinsler, MG | 1 |
| Peters, TJ | 1 |
| Doss, M | 1 |
| Schäfer, HJ | 1 |
| Lai, CW | 2 |
| Peters, HA | 1 |
| Murakami, H | 1 |
| Tamura, J | 1 |
| Karasawa, M | 1 |
| Larson, AW | 1 |
| Wasserstrom, WR | 1 |
| Felsher, BF | 1 |
| Chih, JC | 1 |
| Hung, TP | 1 |
| Lin, WS | 1 |
| Morgan, CJ | 1 |
| Badawy, AA | 1 |
1 review available for carbamazepine and Porphyrias
| Article | Year |
|---|---|
[Porphyrias and drugs].
Topics: Carbamazepine; Contraindications; Estrogens; Hemin; Humans; Hypnotics and Sedatives; Meprobamate; Po | 1995 |
10 other studies available for carbamazepine and Porphyrias
| Article | Year |
|---|---|
Carbamazepine-induced non-hereditary acute porphyria.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Carbamazepine; Diagnosis, Differential; Epilepsy | 1983 |
Carbamazepine-induced non-hereditary acute porphyria.
Topics: Acute Disease; Carbamazepine; Epilepsy; Humans; Porphyrias | 1983 |
Carbamazepine-induced non-hereditary acute porphyria.
Topics: Acute Disease; Carbamazepine; Humans; Porphyrias | 1983 |
Carbamazepine-induced non-hereditary acute porphyria.
Topics: Acute Disease; Carbamazepine; Erythrocytes; Humans; Porphobilinogen Synthase; Porphyrias | 1983 |
Carbamazepine-induced acute porphyria syndrome.
Topics: Acute Disease; Aged; Carbamazepine; Child; Epilepsy; Female; Humans; Middle Aged; Porphyrias; Syndro | 1984 |
Carbamazepine in seizure management in acute intermittent porphyria.
Topics: 5-Aminolevulinate Synthetase; Carbamazepine; Humans; Porphobilinogen; Porphyrias; Seizures | 1981 |
Carbamazepine in seizure management in acute intermittent porphyria.
Topics: Acute Disease; Carbamazepine; Humans; Porphyrias; Seizures | 1981 |
Posttraumatic epilepsy and acute intermittent porphyria: effects of phenytoin, carbamazepine, and clonazepam.
Topics: Acute Disease; Adult; Benzodiazepinones; Carbamazepine; Clonazepam; Epilepsy, Post-Traumatic; Humans | 1978 |
Blindness of cerebral origin in acute intermittent porphyria. Report of a case and postmortem examination.
Topics: Adult; Blindness; Brain; Carbamazepine; Electroencephalography; Epilepsy; Female; Humans; Hypertensi | 1977 |
Effects of acute carbamazepine administration on haem metabolism in rat liver.
Topics: 5-Aminolevulinate Synthetase; Allopurinol; Animals; Carbamazepine; Chemical and Drug Induced Liver I | 1992 |