Page last updated: 2024-10-24

carbamazepine and Parkinson Disease

carbamazepine has been researched along with Parkinson Disease in 13 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
"The phenytoin treatment causes cerebellar defect and anemia."2.82The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches. ( Agrawal, M; Dhurandhar, Y; Panda, SP, 2022)
"Some comorbidities [e."1.48A systematic approach for identifying shared mechanisms in epilepsy and its comorbidities. ( Balzer, N; Domingo-Fernández, D; Güldenpfennig, A; Hofmann-Apitius, M; Hoyt, CT, 2018)
"We identified 8549 patients with Parkinson's disease using diagnosis criteria with a positive predictive value of 90%."1.39The association between Parkinson's disease and anti-epilepsy drug carbamazepine: a case-control study using the UK General Practice Research Database. ( Douglas, I; Skow, A; Smeeth, L, 2013)
"A treatment with carbamazepine was started and proved to be successful."1.39Complex visual hallucinations in a Parkinson patient: don't blame James if it's Charles's fault. ( Segers, K, 2013)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's2 (15.38)18.2507
2000's2 (15.38)29.6817
2010's5 (38.46)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Panda, SP1
Dhurandhar, Y1
Agrawal, M1
Hoyt, CT1
Domingo-Fernández, D1
Balzer, N1
Güldenpfennig, A1
Hofmann-Apitius, M1
Skow, A1
Douglas, I1
Smeeth, L1
Bach, JP1
Oertel, WH1
Dodel, R1
Jessen, F1
Saleh, C1
Xiong, N1
Jia, M1
Chen, C1
Xiong, J1
Zhang, Z1
Huang, J1
Hou, L1
Yang, H1
Cao, X1
Liang, Z1
Sun, S1
Lin, Z1
Wang, T1
Segers, K1
Kovacs, N1
Nagy, F1
Balas, I1
Komoly, S1
Janszky, J1
Stewart, JT1
Yelton, JA1
Gehlen, W1
Clarke, BM1
Upton, A1
Griffin, H1
Hudoba, P1
Tyler, HR1
Udvarhelyi, GB1
Aronson, NI1

Reviews

4 reviews available for carbamazepine and Parkinson Disease

ArticleYear
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches.
    Mitochondrion, 2022, Volume: 66

    Topics: Anticonvulsants; Carbamazepine; Dementia; Epilepsy; Felbamate; Gabapentin; Humans; Inflammasomes; La

2022
[Iatrogenic damage possibilities in the drug therapy of neurologic and psychiatric diseases].
    Medizinische Klinik, 1977, Aug-12, Volume: 72, Issue:32-33

    Topics: Amantadine; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Central Nervous System Di

1977
Advances in neurology.
    The Practitioner, 1968, Volume: 201, Issue:204

    Topics: Analgesics; Anticoagulants; Brain; Brain Neoplasms; Carbamazepine; Cerebrovascular Disorders; Contra

1968
Pain and motor disorders.
    Progress in neurology and psychiatry, 1969, Volume: 24

    Topics: Basal Ganglia; Carbamazepine; Cordotomy; Electromyography; Evoked Potentials; Extrapyramidal Tracts;

1969

Other Studies

9 other studies available for carbamazepine and Parkinson Disease

ArticleYear
A systematic approach for identifying shared mechanisms in epilepsy and its comorbidities.
    Database : the journal of biological databases and curation, 2018, 01-01, Volume: 2018

    Topics: Alzheimer Disease; Carbamazepine; Comorbidity; Data Mining; Databases, Bibliographic; Databases, Gen

2018
The association between Parkinson's disease and anti-epilepsy drug carbamazepine: a case-control study using the UK General Practice Research Database.
    British journal of clinical pharmacology, 2013, Volume: 76, Issue:5

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Case-Control Studies; Databases, Factual; D

2013
Treatment of hypersexuality in Parkinson's disease with carbamazepine--a case report.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Jun-15, Volume: 24, Issue:8

    Topics: Aged, 80 and over; Analgesics, Non-Narcotic; Carbamazepine; Disruptive, Impulse Control, and Conduct

2009
How to treat DBS-induced mania?
    Journal of the neurological sciences, 2011, Feb-15, Volume: 301, Issue:1-2

    Topics: Aged; Bipolar Disorder; Carbamazepine; Clozapine; Deep Brain Stimulation; Female; Humans; Male; Midd

2011
Potential autophagy enhancers attenuate rotenone-induced toxicity in SH-SY5Y.
    Neuroscience, 2011, Dec-29, Volume: 199

    Topics: Apoptosis; Autophagy; Blotting, Western; Carbamazepine; Cell Line, Tumor; Cell Survival; DNA Fragmen

2011
Complex visual hallucinations in a Parkinson patient: don't blame James if it's Charles's fault.
    International psychogeriatrics, 2013, Volume: 25, Issue:3

    Topics: Aged, 80 and over; Anticonvulsants; Carbamazepine; Diagnosis, Differential; Hallucinations; Humans;

2013
Oxcarbazepine may induce psychotic symptoms in Parkinson's disease.
    Epilepsy & behavior : E&B, 2008, Volume: 12, Issue:3

    Topics: Aged; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Male; Oxcarbazepine; Parkinson Disease; Psyc

2008
Treatment of organic hallucinosis with carbamazepine.
    The American journal of psychiatry, 1995, Volume: 152, Issue:1

    Topics: Aged; Aged, 80 and over; Carbamazepine; Female; Hallucinations; Humans; Parkinson Disease

1995
Balance and cognitive impairment in two epileptic patients before and after vagal nerve stimulation.
    Pacing and clinical electrophysiology : PACE, 1991, Volume: 14, Issue:1

    Topics: Adult; Carbamazepine; Cognition; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Humans; Male

1991