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carbamazepine and Panic Disorder

carbamazepine has been researched along with Panic Disorder in 19 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.

Research Excerpts

ExcerptRelevanceReference
"This study was designed to examine the possibility that patients with panic disorder are especially vulnerable to alprazolam withdrawal, as well as to evaluate the efficacy of carbamazepine as adjunctive treatment during alprazolam discontinuation."9.07Alprazolam withdrawal in patients with panic disorder and generalized anxiety disorder: vulnerability and effect of carbamazepine. ( Colin, V; Klein, E; Lenox, RH; Stolk, J, 1994)
"A number of preclinical studies and preliminary clinical reports, in some cases augmented by controlled studies, suggest that valproate and carbamazepine may have therapeutic effects in the treatment of certain anxiety disorders (panic disorder, post-traumatic stress disorder), alcohol and sedative-hypnotic withdrawal states, and behavioral dyscontrol syndromes."8.78Valproate and carbamazepine in the treatment of panic and posttraumatic stress disorders, withdrawal states, and behavioral dyscontrol syndromes. ( Friedman, LM; Keck, PE; McElroy, SL, 1992)
"This analysis is a retrospective chart review evaluating the safety of carbamazepine (CBZ) extended-release capsules (CBZ-ERC) (Shire, Wayne, PA, USA) when used in combination with other agents as part of a polypharmacy regimen in the treatment of patients with bipolar disorder."7.73Safety of carbamazepine extended-release capsules in bipolar disorder polypharmacy. ( Ginsberg, LD, 2006)
"This study was designed to examine the possibility that patients with panic disorder are especially vulnerable to alprazolam withdrawal, as well as to evaluate the efficacy of carbamazepine as adjunctive treatment during alprazolam discontinuation."5.07Alprazolam withdrawal in patients with panic disorder and generalized anxiety disorder: vulnerability and effect of carbamazepine. ( Colin, V; Klein, E; Lenox, RH; Stolk, J, 1994)
"Evidence from preclinical studies, preliminary clinical reports, pharmacologic challenge studies and a small number of controlled trials suggests that several antiepileptic agents--valproate, carbamazepine, and clonazepam--may have therapeutic effects in the treatment of patients with panic disorder."4.78Antiepileptic drugs for the treatment of panic disorder. ( Bennett, JA; Keck, PE; McElroy, SL; Smith, JM; Tugrul, KC, 1993)
"A number of preclinical studies and preliminary clinical reports, in some cases augmented by controlled studies, suggest that valproate and carbamazepine may have therapeutic effects in the treatment of certain anxiety disorders (panic disorder, post-traumatic stress disorder), alcohol and sedative-hypnotic withdrawal states, and behavioral dyscontrol syndromes."4.78Valproate and carbamazepine in the treatment of panic and posttraumatic stress disorders, withdrawal states, and behavioral dyscontrol syndromes. ( Friedman, LM; Keck, PE; McElroy, SL, 1992)
"Maternal epilepsy treated with carbamazepine and migraine were found to be associated with higher risk of ventricular septal defect; panic disorders were associated with higher risk of hypoplastic left heart; type I diabetes mellitus was associated with higher risk of coarctation of the aorta; chronic hypertension was associated with higher risk of ventricular septal defect, common atrioventricular canal and common truncus; and paroxysmal supraventricular tachycardia was associated with higher risk of atrial septal defect secundum, common atrioventricular canal and ventricular septal defect."3.80Association of certain chronic maternal diseases with the risk of specific congenital heart defects: a population-based study. ( Czeizel, AE; Gerencsér, B; Szabó, I; Vereczkey, A, 2014)
"This analysis is a retrospective chart review evaluating the safety of carbamazepine (CBZ) extended-release capsules (CBZ-ERC) (Shire, Wayne, PA, USA) when used in combination with other agents as part of a polypharmacy regimen in the treatment of patients with bipolar disorder."3.73Safety of carbamazepine extended-release capsules in bipolar disorder polypharmacy. ( Ginsberg, LD, 2006)
" In this paper we describe two patients with comorbid epilepsy, major depression, and panic disorder, whose serum citalopram levels increased and antidepressant response changed when concurrent carbamazepine treatment was substituted with oxcarbazepine."3.69Substituting carbamazepine with oxcarbazepine increases citalopram levels. A report on two cases. ( Koponen, H; Leinonen, E; Lepola, U, 1996)
" Under the treatment with carbamazepine panic attacks improved."3.69[Panic attacks with cycloleptic course--differential diagnostic considerations in differentiating panic disorder from epileptic anxiety attacks]. ( Assion, HJ; Heinemann, F, 1996)
"Complex partial epilepsy can be mistaken for primary child-psychiatric disorder."1.35[Panic attacks simulated by occipital lobe seizures]. ( Püst, B; Sieben, C; Stolle, M, 2009)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (73.68)18.2507
2000's3 (15.79)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vereczkey, A1
Gerencsér, B1
Czeizel, AE1
Szabó, I1
Ramos-Zúñiga, R1
Pérez-Gómez, HR1
Gaytán-Martínez, LA1
Vega-Ruiz, B1
Soto-Rodríguez, S1
Rochín-Mozqueda, A1
Stolle, M1
Sieben, C1
Püst, B1
Ginsberg, LD1
Himmerich, H1
Nickel, T1
Dalal, MA1
Müller, MB1
Dantendorfer, K3
Amering, M2
Baischer, W1
Berger, P1
Steinberger, K1
Windhaber, J2
Katschnig, H2
Roy-Byrne, PP1
Sullivan, MD1
Cowley, DS1
Ries, RK1
Klein, E1
Colin, V1
Stolk, J1
Lenox, RH1
Schüler, P1
Kalb, R1
Keck, PE2
McElroy, SL2
Tugrul, KC1
Bennett, JA1
Smith, JM1
Weilburg, JB1
Schachter, S1
Sachs, GS1
Worth, J1
Pollack, MH1
Ives, JR1
Schomer, DL1
Laidlaw, JD1
Leinonen, E1
Lepola, U1
Koponen, H1
Heinemann, F1
Assion, HJ1
Kaendler, SH1
Volk, S1
Pflug, B1
Prayer, D1
Maierhofer, D2
Schnider, P1
Friedman, LM1
McNamara, ME1
Fogel, BS1

Reviews

3 reviews available for carbamazepine and Panic Disorder

ArticleYear
Adjunctive treatment of benzodiazepine discontinuation syndromes: a review.
    Journal of psychiatric research, 1993, Volume: 27 Suppl 1

    Topics: Anti-Anxiety Agents; Benzodiazepines; Carbamazepine; Clonidine; Combined Modality Therapy; Humans; P

1993
Antiepileptic drugs for the treatment of panic disorder.
    Neuropsychobiology, 1993, Volume: 27, Issue:3

    Topics: Anticonvulsants; Carbamazepine; Clonazepam; Humans; Panic Disorder; Valproic Acid

1993
Valproate and carbamazepine in the treatment of panic and posttraumatic stress disorders, withdrawal states, and behavioral dyscontrol syndromes.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:1 Suppl

    Topics: Carbamazepine; Humans; Mental Disorders; Panic Disorder; Stress Disorders, Post-Traumatic; Substance

1992

Trials

1 trial available for carbamazepine and Panic Disorder

ArticleYear
Alprazolam withdrawal in patients with panic disorder and generalized anxiety disorder: vulnerability and effect of carbamazepine.
    The American journal of psychiatry, 1994, Volume: 151, Issue:12

    Topics: Adult; Alprazolam; Anxiety Disorders; Carbamazepine; Double-Blind Method; Drug Administration Schedu

1994

Other Studies

15 other studies available for carbamazepine and Panic Disorder

ArticleYear
Association of certain chronic maternal diseases with the risk of specific congenital heart defects: a population-based study.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 182

    Topics: Adult; Anticonvulsants; Aortic Coarctation; Carbamazepine; Case-Control Studies; Chronic Disease; Di

2014
[Temporal lobe epilepsy and active neurocysticercosis: two representative case reports].
    Revista de neurologia, 2015, Jan-01, Volume: 60, Issue:1

    Topics: Albendazole; Anomia; Anthelmintics; Anticonvulsants; Antipsychotic Agents; Carbamazepine; Citalopram

2015
[Panic attacks simulated by occipital lobe seizures].
    Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie, 2009, Volume: 37, Issue:3

    Topics: Anticonvulsants; Anxiety Disorders; Carbamazepine; Child; Combined Modality Therapy; Compulsive Beha

2009
Safety of carbamazepine extended-release capsules in bipolar disorder polypharmacy.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2006, Volume: 18 Suppl 1

    Topics: Adolescent; Adult; Aged; Antimanic Agents; Anxiety Disorders; Attention Deficit Disorder with Hypera

2006
[Gabapentin treatment in a female patient with panic disorder and adverse effects under carbamazepine during benzodiazepine withdrawal].
    Psychiatrische Praxis, 2007, Volume: 34, Issue:2

    Topics: Aged; Alprazolam; Amines; Antimanic Agents; Benzodiazepines; Carbamazepine; Chemical and Drug Induce

2007
Is there a pathophysiological and therapeutic link between panic disorder and epilepsy?
    Acta psychiatrica Scandinavica, 1995, Volume: 91, Issue:6

    Topics: Adult; Brain; Carbamazepine; Electroencephalography; Epilepsy; Female; Humans; Magnetic Resonance Im

1995
[Anxiety attacks and epileptic seizures. Determining similarities based on a case report].
    Der Nervenarzt, 1994, Volume: 65, Issue:6

    Topics: Adult; Arousal; Carbamazepine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; E

1994
Focal paroxysmal EEG changes during atypical panic attacks.
    The Journal of neuropsychiatry and clinical neurosciences, 1993,Winter, Volume: 5, Issue:1

    Topics: Adult; Brain; Brain Diseases; Carbamazepine; Clonazepam; Electroencephalography; Female; Humans; Mag

1993
Epilepsy mistaken for panic attacks in an adolescent girl.
    BMJ (Clinical research ed.), 1993, Mar-13, Volume: 306, Issue:6879

    Topics: Adolescent; Carbamazepine; Diagnosis, Differential; Electroencephalography; Epilepsies, Partial; Fem

1993
Substituting carbamazepine with oxcarbazepine increases citalopram levels. A report on two cases.
    Pharmacopsychiatry, 1996, Volume: 29, Issue:4

    Topics: Adult; Anticonvulsants; Antidepressive Agents; Carbamazepine; Citalopram; Depressive Disorder; Drug

1996
[Panic attacks with cycloleptic course--differential diagnostic considerations in differentiating panic disorder from epileptic anxiety attacks].
    Psychiatrische Praxis, 1996, Volume: 23, Issue:4

    Topics: Anticonvulsants; Anxiety Disorders; Carbamazepine; Diagnosis, Differential; Epilepsy, Temporal Lobe;

1996
[Benzodiazepine withdrawal with carbamazepine].
    Der Nervenarzt, 1996, Volume: 67, Issue:5

    Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Arousal; Benzodiazepines; Carbamazepine; Delayed-Action

1996
Treatment of Koro and panic attacks after stroke.
    Anxiety, 1996, Volume: 2, Issue:1

    Topics: Anticonvulsants; Carbamazepine; Cerebral Cortex; Cerebral Infarction; Clonazepam; Drug Therapy, Comb

1996
Oxcarbazepine for panic disorder occurring after two grand mal seizures: a case report.
    The Journal of clinical psychiatry, 1997, Volume: 58, Issue:9

    Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy, Tonic-Clonic; Humans; Male; Oxcarbazepine; Panic Di

1997
Anticonvulsant-responsive panic attacks with temporal lobe EEG abnormalities.
    The Journal of neuropsychiatry and clinical neurosciences, 1990,Spring, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Carbamazepine; Clonazepam; Electroencepha

1990