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carbamazepine and Osteomalacia

carbamazepine has been researched along with Osteomalacia in 22 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Osteomalacia: Disorder caused by an interruption of the mineralization of organic bone matrix leading to bone softening, bone pain, and weakness. It is the adult form of rickets resulting from disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis.

Research Excerpts

ExcerptRelevanceReference
"Many anticonvulsants are known to cause osteomalacia, however, carbamazepine has not previously been studied in this regard."7.66Biochemical evidence for osteomalacia with carbamazepine therapy. ( Callaghan, N; Duggan, B; O'Driscoll, D; O'Hare, JA, 1980)
"Many anticonvulsants are known to cause osteomalacia, however, carbamazepine has not previously been studied in this regard."3.66Biochemical evidence for osteomalacia with carbamazepine therapy. ( Callaghan, N; Duggan, B; O'Driscoll, D; O'Hare, JA, 1980)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199012 (54.55)18.7374
1990's2 (9.09)18.2507
2000's6 (27.27)29.6817
2010's2 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Assenza, G1
Campana, C1
Tombini, M1
Cosimo Quattrocchi, C1
Giambattistelli, F1
Benvenga, A1
Pellegrino, G1
Assenza, F1
Vernieri, F1
Di Lazzaro, V1
Rokan, Z1
Kealey, WD1
Tunca, A1
Sayli, U1
Atalar, H1
Doğruel, H1
Pascussi, JM1
Maurel, P1
Vilarem, MJ1
Tjellesen, L3
Gotfredsen, A1
Christiansen, C3
Nilas, L1
Wolschendorf, K1
Vanselow, K1
Möller, WD1
Schulz, H1
Baars, A1
Baars, M1
Beier, R1
Bretschneider, T1
O'Hare, JA1
Duggan, B1
O'Driscoll, D1
Callaghan, N1
Pluskiewicz, W1
Nowakowska, J1
Karaaslan, Y1
Haznedaroğlu, S1
Oztürk, M1
Goraya, JS1
Gupta, PN1
Gupta, RK1
Bahadur, R1
Parmar, VR1
Pedrera, JD1
Canal, ML1
Carvajal, J1
Postigo, S1
Villa, LF1
Hernández, ER1
Rico, H1
Andersen, RS1
Valeur, N1
Lidgren, L2
Nilsson, BE1
Wallöe, A2
Dymling, JF1
Okesina, AB1
Donaldson, D1
Lascelles, PT1
Sotaniemi, EA1
Hakkarainen, HK1
Puranen, JA1
Lahti, RO1
Lücking, T1
Delling, G1
Varkey, K1
Raman, PT1
Bhaktaviziam, A1
Taori, GM1
Linde, J1
Molholm Hansen, J1
Siersbaek-Nielsen, K1
Fuglsang-Fredriksen, V1

Trials

1 trial available for carbamazepine and Osteomalacia

ArticleYear
Influence of vitamin D administration on bone ultrasound measurements in patients on anticonvulsant therapy.
    European journal of clinical investigation, 2000, Volume: 30, Issue:10

    Topics: 25-Hydroxyvitamin D 2; Adult; Aged; Anticonvulsants; Bone and Bones; Calcifediol; Carbamazepine; Epi

2000

Other Studies

21 other studies available for carbamazepine and Osteomalacia

ArticleYear
Osteomalacic myopathy: an uncommon side effect of antiepileptic drugs.
    Muscle & nerve, 2013, Volume: 48, Issue:5

    Topics: Anticonvulsants; Bone Density Conservation Agents; Carbamazepine; Cholecalciferol; Epilepsy; Humans;

2013
Osteomalacia: a forgotten cause of fractures in the elderly.
    BMJ case reports, 2015, Feb-09, Volume: 2015

    Topics: Aged; Anticonvulsants; Carbamazepine; Delayed Diagnosis; Diet; Epilepsy; Femoral Neck Fractures; Hum

2015
Carbamazepine induced osteomalacia: letter to the editor.
    Acta neurologica Belgica, 2005, Volume: 105, Issue:1

    Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Middle Aged; Osteomalacia; Radionuclide Im

2005
Response to Zhou et al. Osteomalacia is a frequent complication resulting from long-term therapy with drugs such as phenytoin, carbamazepine, and phenobarbital.
    The Journal of clinical investigation, 2006, Volume: 116, Issue:10

    Topics: Anticonvulsants; Carbamazepine; Constitutive Androstane Receptor; Gene Expression; Humans; Osteomala

2006
Effect of vitamin D2 and D3 on bone-mineral content in carbamazepine-treated epileptic patients.
    Acta neurologica Scandinavica, 1983, Volume: 68, Issue:6

    Topics: Adult; Aged; Bone and Bones; Carbamazepine; Cholecalciferol; Epilepsy; Ergocalciferols; Female; Huma

1983
Does carbamazepine cause disturbances in calcium metabolism in epileptic patients?
    Acta neurologica Scandinavica, 1983, Volume: 68, Issue:1

    Topics: Adolescent; Adult; Aged; Bone and Bones; Calcifediol; Calcium; Carbamazepine; Epilepsy; Female; Huma

1983
A quantitative determination of anticonvulsant-induced bone demineralization by an improved X-ray densitometry technique.
    Neuroradiology, 1983, Volume: 25, Issue:5

    Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Anticonvulsants; Bone and Bones; Carbamazepine; Dru

1983
Serum vitamin D metabolites in epileptic patients treated with 2 different anti-convulsants.
    Acta neurologica Scandinavica, 1982, Volume: 66, Issue:3

    Topics: 24,25-Dihydroxyvitamin D 3; Adult; Aged; Alkaline Phosphatase; Calcifediol; Calcitriol; Calcium; Car

1982
[Diagnosis of osteopathy caused by antiepileptic drugs].
    Zeitschrift fur arztliche Fortbildung, 1981, Aug-01, Volume: 75, Issue:15

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Bone Diseases; Carbamazepine; Epilepsy; Female; Femur; Han

1981
Biochemical evidence for osteomalacia with carbamazepine therapy.
    Acta neurologica Scandinavica, 1980, Volume: 62, Issue:5

    Topics: Adolescent; Adult; Alkaline Phosphatase; Bilirubin; Carbamazepine; Child; Enzyme Induction; Epilepsy

1980
Bone status after long-term anticonvulsant therapy in epileptic patients: evaluation using quantitative ultrasound of calcaneus and phalanges.
    Ultrasound in medicine & biology, 1997, Volume: 23, Issue:4

    Topics: Adult; Anticonvulsants; Calcaneus; Carbamazepine; Case-Control Studies; Drug Therapy, Combination; E

1997
Osteomalacia associated with carbamazepine/valproate.
    The Annals of pharmacotherapy, 2000, Volume: 34, Issue:2

    Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Osteomalacia; Valproic Acid

2000
Anticonvulsant induced osteomalacia.
    Indian pediatrics, 2000, Volume: 37, Issue:3

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant; Male; Osteomalacia; Ph

2000
[Hyperparathyroidism secondary to anticonvulsant treatment].
    Ugeskrift for laeger, 2001, Nov-05, Volume: 163, Issue:45

    Topics: Alkaline Phosphatase; Anticonvulsants; Calcifediol; Carbamazepine; Female; Humans; Hyperparathyroidi

2001
Bone mineral content in epileptics.
    Calcified tissue international, 1979, Oct-31, Volume: 28, Issue:2

    Topics: Aged; Bone and Bones; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Minerals; Muscle C

1979
Biochemical variables related to calcium metabolism in epileptics.
    Acta medica Scandinavica, 1979, Volume: 205, Issue:5

    Topics: Aged; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilepsy; Female; Humans; Male;

1979
Isoenzymes of alkaline phosphatase in epileptic patients receiving carbamazepine monotherapy.
    Journal of clinical pathology, 1991, Volume: 44, Issue:6

    Topics: Adult; Aged; Alkaline Phosphatase; Bone and Bones; Carbamazepine; Epilepsy; Female; Humans; Isoenzym

1991
Radiologic bone changes and hypocalcemia with anticonvulsant therapy in epilepsy.
    Annals of internal medicine, 1972, Volume: 77, Issue:3

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Anticonvulsants; Back Pain; Calcium; Carbamazepine; D

1972
[Severe rachitic osteopathy during long-term anticonvulsant treatment].
    Deutsche medizinische Wochenschrift (1946), 1973, May-18, Volume: 98, Issue:20

    Topics: Administration, Oral; Alkaline Phosphatase; Anticonvulsants; Biopsy; Calcium; Carbamazepine; Child;

1973
Osteomalacia due to phenytoin sodium. A case report with review of literature.
    Journal of the neurological sciences, 1973, Volume: 19, Issue:3

    Topics: Adult; Bone and Bones; Calcium; Carbamazepine; Clavicle; Deficiency Diseases; Female; Folic Acid; Hu

1973
Bone density in patients receiving long-term anticonvulsant therapy.
    Acta neurologica Scandinavica, 1971, Volume: 47, Issue:5

    Topics: Absorptiometry, Photon; Adult; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilep

1971