Page last updated: 2024-10-24

carbamazepine and Neutropenia

carbamazepine has been researched along with Neutropenia in 13 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.

Research Excerpts

ExcerptRelevanceReference
"To estimate the incidence of pancytopenia in patients taking leflunomide with or without methotrexate in Australia."7.74The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate. ( Calcino, LJ; Hill, RL; McEwen, J; Purcell, PM; Riley, CG, 2007)
"One hundred seventy-six children treated with carbamazepine for epilepsy were monitored over a 12-month period to determine the effects of carbamazepine on the hematologic system."7.67Hematologic monitoring in children with epilepsy treated with carbamazepine. ( Evans, OB; Gay, H; Parks, B; Swisher, A, 1989)
"Carbamazepine is an antiepileptic drug used in the treatment of epilepsy, trigeminal neuralgia, and bipolar disorder."4.31Acute lymphocytic leukemia in a patient with long-term carbamazepine exposure: Acute lymphoblastic leukemia that develops in a patient who has been using carbamazepine for a long time. ( Bagci, M; Sayin, S, 2023)
"To estimate the incidence of pancytopenia in patients taking leflunomide with or without methotrexate in Australia."3.74The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate. ( Calcino, LJ; Hill, RL; McEwen, J; Purcell, PM; Riley, CG, 2007)
"Carbamazepine is a commonly used anticonvulsant agent, particularly in the management of partial seizures."3.67Leucopenia as an adverse reaction to carbamazepine therapy. ( Beran, RG; Rush, JA, 1984)
"One hundred seventy-six children treated with carbamazepine for epilepsy were monitored over a 12-month period to determine the effects of carbamazepine on the hematologic system."3.67Hematologic monitoring in children with epilepsy treated with carbamazepine. ( Evans, OB; Gay, H; Parks, B; Swisher, A, 1989)
"Carbamazepine is a commonly used anticonvulsant agent; however, it has been linked with various blood cell abnormalities."2.72Folic acid supplementation reduces the development of some blood cell abnormalities in children receiving carbamazepine. ( Asadi-Pooya, AA; Ghetmiri, E, 2006)
"A patient developed toxic epidermal necrolysis while on carbamazepine, 80% of her skin surface being involved."1.30Toxic epidermal necrolysis treated with cyclosporin and granulocyte colony stimulating factor. ( Havill, J; Jarrett, P; Pullon, H; Rademaker, M, 1997)
"Carbamazepine was found to cause statistically significant, but clinically insubstantial, decreases in white blood cell indexes."1.27Hematological effects of carbamazepine in patients with affective illness. ( Joffe, RT; Post, RM; Roy-Byrne, PP; Uhde, TW, 1985)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's2 (15.38)18.2507
2000's2 (15.38)29.6817
2010's1 (7.69)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Sayin, S1
Bagci, M1
Hsiao, YT1
Wei, IH1
Huang, CC1
Asadi-Pooya, AA1
Ghetmiri, E1
McEwen, J1
Purcell, PM1
Hill, RL1
Calcino, LJ1
Riley, CG1
Boissier, MC1
Sansonetti, P1
Dupont, B1
Lapresle, C1
Brain, C1
Mac Ardle, B1
Levin, S1
Rush, JA1
Beran, RG1
Jarrett, P1
Rademaker, M1
Havill, J1
Pullon, H1
Vaĭntrub, MIa1
Shapiro, IuL1
Mastrosimone, F1
Capo, G1
Colucci D'Amato, C1
Evans, OB1
Gay, H1
Swisher, A1
Parks, B1
Joffe, RT1
Post, RM1
Roy-Byrne, PP1
Uhde, TW1

Trials

1 trial available for carbamazepine and Neutropenia

ArticleYear
Folic acid supplementation reduces the development of some blood cell abnormalities in children receiving carbamazepine.
    Epilepsy & behavior : E&B, 2006, Volume: 8, Issue:1

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Dietary Supplements; Female; Folic Acid; Hematini

2006

Other Studies

12 other studies available for carbamazepine and Neutropenia

ArticleYear
Acute lymphocytic leukemia in a patient with long-term carbamazepine exposure: Acute lymphoblastic leukemia that develops in a patient who has been using carbamazepine for a long time.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:2

    Topics: Anemia, Aplastic; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Neutropenia; Precursor Cell Lymp

2023
Oxcarbazepine-related neutropenia: a case report.
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:1

    Topics: Adult; Anticonvulsants; Bipolar Disorder; Carbamazepine; Female; Humans; Neutropenia; Oxcarbazepine

2010
The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate.
    Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; An

2007
[Major intolerance to carbamazepine. Acquired immunodepression or allergy?].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Nov-24, Volume: 59, Issue:43

    Topics: Carbamazepine; Child; Drug Eruptions; Drug Hypersensitivity; Humans; Immunity; Male; Neutropenia

1983
Idiosyncratic reactions to carbamazepine mimicking viral infection in children.
    British medical journal (Clinical research ed.), 1984, Aug-11, Volume: 289, Issue:6441

    Topics: Adolescent; Agranulocytosis; Carbamazepine; Child; Diagnosis, Differential; Female; Humans; Infant;

1984
Leucopenia as an adverse reaction to carbamazepine therapy.
    The Medical journal of Australia, 1984, Mar-31, Volume: 140, Issue:7

    Topics: Adult; Agranulocytosis; Carbamazepine; Dose-Response Relationship, Drug; Female; Humans; Leukocyte C

1984
Anticonvulsant hypersensitivity.
    The Medical journal of Australia, 1994, May-16, Volume: 160, Issue:10

    Topics: Carbamazepine; Drug Hypersensitivity; Humans; Male; Middle Aged; Neutropenia; Phenytoin; Skin Diseas

1994
Toxic epidermal necrolysis treated with cyclosporin and granulocyte colony stimulating factor.
    Clinical and experimental dermatology, 1997, Volume: 22, Issue:3

    Topics: Adult; Analgesics, Non-Narcotic; Carbamazepine; Cyclosporine; Female; Filgrastim; Granulocyte Colony

1997
[Neutropenia in epilepsy patients].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979, Volume: 79, Issue:3

    Topics: Adolescent; Adult; Agranulocytosis; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epile

1979
[The use of lithium salts in trigeminal neuralgia in prevention of neutropenia due to carbamazepine. Preliminary considerations].
    Acta neurologica. Quaderni, 1979, Volume: 39

    Topics: Aged; Agranulocytosis; Carbamazepine; Female; Humans; Lithium; Male; Middle Aged; Neutropenia; Risk;

1979
Hematologic monitoring in children with epilepsy treated with carbamazepine.
    Journal of child neurology, 1989, Volume: 4, Issue:4

    Topics: Agranulocytosis; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Follow-Up Studies; Humans

1989
Hematological effects of carbamazepine in patients with affective illness.
    The American journal of psychiatry, 1985, Volume: 142, Issue:10

    Topics: Adult; Anemia; Anemia, Aplastic; Bipolar Disorder; Carbamazepine; Diagnosis, Differential; Erythrocy

1985