carbamazepine has been researched along with Nervous System Disorders in 43 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study evaluated the potentiation by glycine of anticonvulsant drugs in maximal electroshock seizures in rats." | 7.68 | Potentiation by glycine of anticonvulsant drugs in maximal electroshock seizures in rats. ( Adams, HR; Frye, GD; Peterson, SL; Trzeciakowski, JP, 1990) |
| "Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment." | 5.27 | Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983) |
| " Reversible dystonia may occasionally be precipitated by phenytoin or carbamazepine; asterixis by phenytoin, barbiturates or carbamazepine; and, more commonly, tremor by valproate." | 4.77 | Adverse neuropsychiatric effects of anticonvulsant drugs. ( Reynolds, EH; Trimble, MR, 1985) |
| " We differentiated and treated human SK-N-SH neuroblastoma cells with a mixture (fluoxetine, carbamazepine and venlafaxine) and valproate (used as a positive control to induce autism-associated profiles), followed by transcriptome analysis with RNA-Seq approach." | 3.83 | Psychoactive pharmaceuticals at environmental concentrations induce in vitro gene expression associated with neurological disorders. ( Kaushik, G; Thomas, MA; Xia, Y; Yang, L, 2016) |
| " Carbamazepine was reported to be moderately to markedly effective in the following percentage of patients: partial complex seizures, 85." | 3.69 | Efficacy of carbamazepine compared with other agents: a clinical practice survey. ( Denicoff, KD; Meglathery, SB; Post, RM; Tandeciarz, SI, 1994) |
| "A patient with epilepsy controlled by carbamazepine developed a carbamazepine neurotoxic reaction after being given an increased dosage of diltiazem hydrochloride as adjunctive therapy." | 3.68 | Carbamazepine neurotoxic reaction after administration of diltiazem. ( Grossman, E; Maoz, E; Rosenthal, T; Thaler, M, 1992) |
| "This study evaluated the potentiation by glycine of anticonvulsant drugs in maximal electroshock seizures in rats." | 3.68 | Potentiation by glycine of anticonvulsant drugs in maximal electroshock seizures in rats. ( Adams, HR; Frye, GD; Peterson, SL; Trzeciakowski, JP, 1990) |
| "Analysis of overall tolerability and neurological adverse effects (AEs) of eslicarbazepine acetate (ESL), lacosamide (LCM) and oxcarbazepine (OXC) from double-blind, placebo-controlled trials." | 2.49 | Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine. ( Fadda, V; Giovannelli, F; Maratea, D; Verrotti, A; Zaccara, G, 2013) |
| "Neuropathic cranial pain, i." | 2.42 | Neuropathic cranial pain. ( Annovazzi, PO; Colombo, B; Comi, G, 2003) |
| " Adverse effects of antiepileptic treatment may affect the patient's quality of life to an even greater extent than the occurrence of seizures." | 2.39 | Adverse effects of established and new antiepileptic drugs: an attempted comparison. ( Gram, L; Rogvi-Hansen, B, 1995) |
| "A majority of cases of idiopathic autism in children likely result from unknown environmental triggers in genetically susceptible individuals." | 1.46 | Dysregulation of autism-associated synaptic proteins by psychoactive pharmaceuticals at environmental concentrations. ( Kaushik, G; Pfau, JC; Thomas, MA; Xia, Y, 2017) |
| "There were 73 children with seizures, 80% of whom had a greater than 50% reduction in seizure frequency following the start of simple anticonvulsant medication." | 1.32 | A review of neurological disorders presenting at a paediatric neurology clinic and response to anticonvulsant therapy in Gambian children. ( Allen, S; Burton, KJ, 2003) |
| " The neurotoxicity induced by carbamazepine may be involved in the teratogenic and adverse effects of overdose associated with the treatment of manic-depressive illness and seizures." | 1.28 | Carbamazepine-induced neurotoxicity and its prevention by NMDA in cultured cerebellar granule cells. ( Chuang, DM; Gao, XM, 1992) |
| "Seizures are a recognized manifestation of neurosarcoidosis, but their clinical relevance is not well established." | 1.28 | Clinical implications of seizures in neurosarcoidosis. ( Krumholz, A; Stern, BJ; Stern, EG, 1991) |
| " The serum levels for effective and safe dosage have been determined when these drugs are used alone." | 1.28 | Avoiding neurotoxicity with lithium-carbamazepine combinations. ( Hollister, LE; Kishimoto, A; McGinness, J, 1990) |
| "A diagnostic approach to syncope in head and neck cancer is proposed." | 1.28 | Evaluation of syncope from head and neck cancer. ( Gordon, T; Levine, HL; Papay, FA; Roberts, JK; Wegryn, TL, 1989) |
| "Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment." | 1.27 | Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983) |
| " The toxicity resolved when the carbamazepine dosage was decreased 62 percent." | 1.27 | Elevated serum carbamazepine concentrations following diltiazem initiation. ( Carter, BL; Eimer, M, 1987) |
| "Carbamazepine, 200 mg daily was administrated and showed a dramatic reversal of the symptoms." | 1.27 | [A case of Isaac's syndrome--continuous muscle fiber activity syndrome]. ( Kaji, M; Kuwasaki, N; Nonaka, K; Shoji, H; Tominaga, H, 1986) |
| "Only 21% of those with myoclonic astatic epilepsy have become free from seizures." | 1.26 | Sodium valproate: monotherapy and polytherapy. ( Covanis, A; Gupta, AK; Jeavons, PM, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (55.81) | 18.7374 |
| 1990's | 10 (23.26) | 18.2507 |
| 2000's | 5 (11.63) | 29.6817 |
| 2010's | 4 (9.30) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaushik, G | 2 |
| Xia, Y | 2 |
| Pfau, JC | 1 |
| Thomas, MA | 2 |
| Zaccara, G | 1 |
| Giovannelli, F | 1 |
| Maratea, D | 1 |
| Fadda, V | 1 |
| Verrotti, A | 1 |
| Chen, CY | 1 |
| Xiao, F | 1 |
| Liu, JL | 1 |
| Yang, L | 1 |
| Lordos, EF | 1 |
| Trombert, V | 1 |
| Vogt, N | 1 |
| Perrenoud, JJ | 1 |
| Burton, KJ | 1 |
| Allen, S | 1 |
| Colombo, B | 1 |
| Annovazzi, PO | 1 |
| Comi, G | 1 |
| Goicoechea, M | 1 |
| Best, B | 1 |
| Capparelli, E | 1 |
| Haubrich, R | 1 |
| Brahmi, N | 1 |
| Kouraichi, N | 1 |
| Abderrazek, H | 1 |
| Thabet, H | 1 |
| Amamou, M | 1 |
| Chaudhry, RP | 1 |
| Waters, BG | 1 |
| Keränen, T | 1 |
| Sivenius, J | 1 |
| Shukla, S | 1 |
| Godwin, CD | 1 |
| Long, LE | 1 |
| Miller, MG | 1 |
| Jusić, A | 1 |
| Ahmetović, V | 1 |
| Mardesić, D | 1 |
| Covanis, A | 1 |
| Gupta, AK | 1 |
| Jeavons, PM | 1 |
| Sillanpää, M | 1 |
| Amedee-Manesme, O | 1 |
| Rey, E | 1 |
| Brussieux, J | 1 |
| Goutieres, F | 1 |
| Aicardi, J | 1 |
| Denicoff, KD | 1 |
| Meglathery, SB | 1 |
| Post, RM | 1 |
| Tandeciarz, SI | 1 |
| Rogvi-Hansen, B | 1 |
| Gram, L | 1 |
| Alegre Herrera, S | 1 |
| Araujo Sanabria, J | 1 |
| Rubio Rubio, JM | 1 |
| Gehlen, W | 1 |
| Metz, SA | 1 |
| Halter, JB | 1 |
| Porte, D | 1 |
| Robertson, RP | 1 |
| Yagi, K | 1 |
| Watanabe, M | 1 |
| Gao, XM | 1 |
| Chuang, DM | 1 |
| Maoz, E | 1 |
| Grossman, E | 1 |
| Thaler, M | 1 |
| Rosenthal, T | 1 |
| ten Berg, JM | 1 |
| de Waal, WJ | 1 |
| Mauser, HW | 1 |
| Krumholz, A | 1 |
| Stern, BJ | 1 |
| Stern, EG | 1 |
| McGinness, J | 1 |
| Kishimoto, A | 1 |
| Hollister, LE | 1 |
| Peterson, SL | 1 |
| Trzeciakowski, JP | 1 |
| Frye, GD | 1 |
| Adams, HR | 1 |
| Piccione, E | 1 |
| Ticconi, C | 1 |
| Cennamo, M | 1 |
| Oles, KS | 1 |
| Mirza, W | 1 |
| Penry, JK | 1 |
| Reynolds, EH | 1 |
| Trimble, MR | 1 |
| Papay, FA | 1 |
| Roberts, JK | 1 |
| Wegryn, TL | 1 |
| Gordon, T | 1 |
| Levine, HL | 1 |
| Brodie, MJ | 1 |
| MacPhee, GJ | 1 |
| Price, WA | 2 |
| DiMarzio, LR | 1 |
| Login, IS | 1 |
| Eimer, M | 1 |
| Carter, BL | 1 |
| Patsalos, PN | 1 |
| Krishna, S | 1 |
| Elyas, AA | 1 |
| Lascelles, PT | 1 |
| Kuwasaki, N | 1 |
| Shoji, H | 1 |
| Tominaga, H | 1 |
| Kaji, M | 1 |
| Nonaka, K | 1 |
| Zimmer, B | 1 |
| Cendrowski, W | 1 |
| Gayford, JJ | 1 |
| Redpath, TH | 1 |
| Müller, J | 1 |
| Müller, D | 1 |
| Espir, ML | 1 |
| Millac, P | 1 |
8 reviews available for carbamazepine and Nervous System Disorders
| Article | Year |
|---|---|
Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine.
Topics: Acetamides; Anticonvulsants; Ataxia; Carbamazepine; Dibenzazepines; Diplopia; Dizziness; Dose-Respon | 2013 |
Neuropathic cranial pain.
Topics: Acetates; Amines; Analgesics; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents, Tric | 2003 |
Adverse effects of established and new antiepileptic drugs: an attempted comparison.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; gamma-Aminobutyric Acid; Gastrointestinal Disease | 1995 |
[Iatrogenic damage possibilities in the drug therapy of neurologic and psychiatric diseases].
Topics: Amantadine; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Central Nervous System Di | 1977 |
[Neurotoxicity of antiepileptic drugs].
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Ethosuximide; Humans; Male; Nervous S | 1992 |
[Problems of neurological drug therapy in pregnancy].
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Antiparkinson Agents; Carbamazepine; Chelating Agents; | 1989 |
Adverse neuropsychiatric effects of anticonvulsant drugs.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biogenic Amines; Carba | 1985 |
The side-effects of carbamazepine.
Topics: Amitriptyline; Anemia, Aplastic; Carbamazepine; Dibenzazepines; Gastrointestinal Diseases; Humans; I | 1969 |
1 trial available for carbamazepine and Nervous System Disorders
| Article | Year |
|---|---|
Treatment of paroxysmal disorders in multiple sclerosis with carbamazepine (Tegretol).
Topics: Administration, Oral; Adult; Carbamazepine; Dibenzazepines; Female; Humans; Male; Middle Aged; Multi | 1970 |
34 other studies available for carbamazepine and Nervous System Disorders
| Article | Year |
|---|---|
Dysregulation of autism-associated synaptic proteins by psychoactive pharmaceuticals at environmental concentrations.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Brain; Carbamazepine; Environment; Female; Flu | 2017 |
Superficial siderosis of the central nervous system with seizures onset.
Topics: Ataxia; Carbamazepine; Carcinoma; Central Nervous System; Diagnosis, Differential; Female; Gait; Hum | 2015 |
Psychoactive pharmaceuticals at environmental concentrations induce in vitro gene expression associated with neurological disorders.
Topics: Animals; Autistic Disorder; Carbamazepine; Cell Line, Tumor; Environmental Pollutants; Fluoxetine; G | 2016 |
Antiepileptic drugs in the treatment of neuropathic pain: drug-to-drug interaction in elderly people.
Topics: Aged, 80 and over; Analgesics; Anticonvulsants; Carbamazepine; Drug Interactions; Female; Humans; Ne | 2009 |
A review of neurological disorders presenting at a paediatric neurology clinic and response to anticonvulsant therapy in Gambian children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Developmental Disabilities; Fem | 2003 |
Concurrent use of efavirenz and oxcarbazepine may not affect efavirenz plasma concentrations.
Topics: Adult; Alkynes; Anti-HIV Agents; Anticonvulsants; Benzoxazines; Bipolar Disorder; Carbamazepine; Cyc | 2006 |
Clinical experience with carbamazepine overdose: relationship between serum concentration and neurological severity.
Topics: Adult; Carbamazepine; Coma; Drug Overdose; Female; Humans; Male; Nervous System Diseases; Retrospect | 2008 |
Lithium and carbamazepine interaction: possible neurotoxicity.
Topics: Adult; Bipolar Disorder; Carbamazepine; Drug Synergism; Drug Therapy, Combination; Female; Humans; L | 1983 |
Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy.
Topics: Abnormalities, Drug-Induced; Arousal; Benzodiazepinones; Carbamazepine; Chemical and Drug Induced Li | 1983 |
Lithium-carbamazepine neurotoxicity and risk factors.
Topics: Adult; Bipolar Disorder; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Female; Humans | 1984 |
Acute polyneuropathy with severe generalized rigidity in a child aged 16 months. Preliminary report.
Topics: Acute Disease; Carbamazepine; Electromyography; Humans; Infant; Male; Muscle Rigidity; Nervous Syste | 1984 |
Sodium valproate: monotherapy and polytherapy.
Topics: Adolescent; Adult; Carbamazepine; Drug Therapy, Combination; Epilepsies, Myoclonic; Epilepsies, Part | 1982 |
Carbamazepine. Pharmacology and clinical uses.
Topics: Adult; Alcohol Withdrawal Delirium; Arrhythmias, Cardiac; Behavior; Carbamazepine; Child; Diabetes I | 1981 |
[Antibiotics which must never be combined with carbamazepine].
Topics: Anti-Bacterial Agents; Carbamazepine; Child; Drug Interactions; Female; Humans; Nervous System Disea | 1982 |
Efficacy of carbamazepine compared with other agents: a clinical practice survey.
Topics: Attitude of Health Personnel; Bipolar Disorder; Carbamazepine; Drug Utilization; Electroconvulsive T | 1994 |
[Clarithromycin-carbamazepine interaction: neurological symptoms and hyponatremia].
Topics: Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Clarithromycin; Drug Interactions; Humans; Hy | 1998 |
Autonomic epilepsy: clonidine blockade of paroxysmal catecholamine release and flushing.
Topics: Autonomic Nervous System; Carbamazepine; Catecholamines; Climacteric; Clonidine; Epilepsy; Epilepsy, | 1978 |
Carbamazepine-induced neurotoxicity and its prevention by NMDA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Carbamazepine; Cells, Cultured; Cerebell | 1992 |
Carbamazepine neurotoxic reaction after administration of diltiazem.
Topics: Carbamazepine; Diltiazem; Drug Interactions; Epilepsy; Female; Humans; Hypertension; Middle Aged; Ne | 1992 |
[Paroxysmal symptoms as initial expression of multiple sclerosis].
Topics: Adult; Carbamazepine; Diplopia; Dysarthria; Female; Gait; Humans; Multiple Sclerosis; Muscle Cramp; | 1992 |
Clinical implications of seizures in neurosarcoidosis.
Topics: Adolescent; Adult; Brain Diseases; Carbamazepine; Female; Humans; Male; Middle Aged; Nervous System | 1991 |
Avoiding neurotoxicity with lithium-carbamazepine combinations.
Topics: Carbamazepine; Drug Therapy, Combination; Humans; Lithium; Nervous System Diseases | 1990 |
Potentiation by glycine of anticonvulsant drugs in maximal electroshock seizures in rats.
Topics: Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Chromatography, High Pressure Liquid; Diaz | 1990 |
Catastrophic neurologic signs due to drug interaction: Tegretol and Darvon.
Topics: Adult; Carbamazepine; Dextropropoxyphene; Drug Interactions; Female; Humans; Male; Middle Aged; Nerv | 1989 |
Evaluation of syncope from head and neck cancer.
Topics: Carbamazepine; Carcinoma, Squamous Cell; Glossopharyngeal Nerve; Head and Neck Neoplasms; Heart Dise | 1989 |
Carbamazepine neurotoxicity precipitated by diltiazem.
Topics: Adult; Benzazepines; Carbamazepine; Diltiazem; Drug Interactions; Humans; Male; Nervous System Disea | 1986 |
Verapamil-carbamazepine neurotoxicity.
Topics: Bipolar Disorder; Carbamazepine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Middle A | 1988 |
Unfavorable response to pink Tegretol tablets.
Topics: Carbamazepine; Coloring Agents; Humans; Male; Middle Aged; Nervous System Diseases | 1988 |
Elevated serum carbamazepine concentrations following diltiazem initiation.
Topics: Aged; Carbamazepine; Diltiazem; Drug Interactions; Female; Humans; Nervous System Diseases | 1987 |
Carbamazepine and carbamazepine-10,11-epoxide pharmacokinetics in an overdose patient.
Topics: Adolescent; Carbamazepine; Female; Half-Life; Humans; Kinetics; Nervous System Diseases | 1987 |
[A case of Isaac's syndrome--continuous muscle fiber activity syndrome].
Topics: Adult; Carbamazepine; Electroencephalography; Electromyography; Fasciculation; Female; Humans; Hyper | 1986 |
Lithium-carbamazepine neurotoxicity in the elderly.
Topics: Aged; Carbamazepine; Drug Therapy, Combination; Female; Humans; Lithium; Lithium Carbonate; Nervous | 1985 |
[Paroxysmal ataxia, tonic spasms and paroxysmal paralysis in multiple sclerosis].
Topics: Adrenocorticotropic Hormone; Adult; Body Temperature; Carbamazepine; Cerebellar Ataxia; Electroencep | 1971 |
[Correlation between brain electric activity and overdose of anticonvulsants].
Topics: Anticonvulsants; Barbiturates; Bromine; Carbamazepine; Electroencephalography; Humans; Hydantoins; N | 1972 |