Page last updated: 2024-10-24

carbamazepine and Neoplasms

carbamazepine has been researched along with Neoplasms in 17 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
" In three cases, carbamazepine therapy was withdrawn because of somnolence and vomiting before chemotherapy."9.19Carbamazepine for prevention of chemotherapy-induced nausea and vomiting: a pilot study. ( Cruz, FM; Del Giglio, A; Glasberg, J; Santana, TA; Trufelli, DC, 2014)
" In three cases, carbamazepine therapy was withdrawn because of somnolence and vomiting before chemotherapy."5.19Carbamazepine for prevention of chemotherapy-induced nausea and vomiting: a pilot study. ( Cruz, FM; Del Giglio, A; Glasberg, J; Santana, TA; Trufelli, DC, 2014)
" In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome."4.80Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000)
"The drug of choice for treating trigeminal neuralgia is still carbamazepine."2.82TREATMENT OPTIONS FOR TRIGEMINAL NEURALGIA. ( Radoš, I, 2022)
"Free phenytoin was <1 mg/l on 132 occasions (51."2.72Interactions of serum albumin, valproic acid and carbamazepine with the pharmacokinetics of phenytoin in cancer patients. ( Beijnen, JH; Boogerd, W; Huitema, AD; Joerger, M; Schellens, JH; van der Sande, JJ, 2006)
"Neuropathic pain is usually considered an "hard pain" both for the intrinsic difficulties in a correct diagnosis, and for the modest efficacy of the most part of conventional treatments."2.47[Neuropathic pain in oncology. Novel evidence for clinical practice]. ( Carloni, F; Castellani, C; Drudi, F; Possenti, C; Santelmo, C; Tassinari, D, 2011)
"Phenytoin has been causally implicated in three human cancers: lymphoma, myeloma and neuroblastoma, the latter specifically in the setting of foetal hydantoin syndrome."2.43Cancer risk in people with epilepsy: the role of antiepileptic drugs. ( Driever, PH; Sander, JW; Singh, G, 2005)
"Carbamazepine was associated with a decreased cancer risk (OR Model I: 0."1.62Anti-seizure medication is not associated with an increased risk to develop cancer in epilepsy patients. ( Hamer, HM; Kostev, K; Lang, JD; Mueller, TM; Reindl, C; Stritzelberger, J; Westermayer, V, 2021)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19904 (23.53)18.7374
1990's2 (11.76)18.2507
2000's4 (23.53)29.6817
2010's4 (23.53)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Tukey, RH1
Strassburg, CP1
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Ahmadi, R1
Sepehri, B1
Irani, M1
Ghavami, R1
Radoš, I1
Stritzelberger, J1
Lang, JD1
Mueller, TM1
Reindl, C1
Westermayer, V1
Kostev, K1
Hamer, HM1
Santana, TA1
Cruz, FM1
Trufelli, DC1
Glasberg, J1
Del Giglio, A1
Chu, SH1
Lee, YJ1
Lee, ES1
Geng, Y1
Wang, XS1
Cleeland, CS1
Tassinari, D1
Drudi, F1
Carloni, F1
Possenti, C1
Santelmo, C1
Castellani, C1
Singh, G1
Driever, PH1
Sander, JW1
Joerger, M1
Huitema, AD1
Boogerd, W1
van der Sande, JJ1
Schellens, JH1
Beijnen, JH1
Roy, DJ1
MacDonald, N1
Lipton, S1
Adler, RH1
Storey, P1
Trumble, M1
Yoshimasu, F1
Kurland, LT1
Elveback, LR1
Mullan, S1

Reviews

6 reviews available for carbamazepine and Neoplasms

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia;

2000
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
TREATMENT OPTIONS FOR TRIGEMINAL NEURALGIA.
    Acta clinica Croatica, 2022, Volume: 61, Issue:Suppl 2

    Topics: Carbamazepine; Humans; Neoplasms; Neuralgia; Trigeminal Nerve; Trigeminal Neuralgia

2022
Current use of drugs affecting the central nervous system for chemotherapy-induced peripheral neuropathy in cancer patients: a systematic review.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015, Volume: 23, Issue:2

    Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Antineoplastic Agents; Boronic Acids; Bortezo

2015
[Neuropathic pain in oncology. Novel evidence for clinical practice].
    Recenti progressi in medicina, 2011, Volume: 102, Issue:5

    Topics: Amines; Amitriptyline; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anti

2011
Cancer risk in people with epilepsy: the role of antiepileptic drugs.
    Brain : a journal of neurology, 2005, Volume: 128, Issue:Pt 1

    Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Neoplasms; Phenobarbital; Phenytoin; Rats

2005

Trials

2 trials available for carbamazepine and Neoplasms

ArticleYear
Carbamazepine for prevention of chemotherapy-induced nausea and vomiting: a pilot study.
    Sao Paulo medical journal = Revista paulista de medicina, 2014, Volume: 132, Issue:3

    Topics: Antiemetics; Antineoplastic Agents; Carbamazepine; Female; Humans; Middle Aged; Nausea; Neoplasms; P

2014
Interactions of serum albumin, valproic acid and carbamazepine with the pharmacokinetics of phenytoin in cancer patients.
    Basic & clinical pharmacology & toxicology, 2006, Volume: 99, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Algorithms; Analysis of Variance; Antineoplast

2006

Other Studies

9 other studies available for carbamazepine and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
    Combinatorial chemistry & high throughput screening, 2023, Volume: 26, Issue:4

    Topics: Antineoplastic Agents; Binding Sites; Carbamazepine; Humans; Molecular Docking Simulation; Molecular

2023
Anti-seizure medication is not associated with an increased risk to develop cancer in epilepsy patients.
    Journal of neurology, 2021, Volume: 268, Issue:6

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Germany; Humans; Middle Aged; Neo

2021
The Brandes-Friesen case reports: how should we interpret the news?
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1995, Sep-01, Volume: 153, Issue:5

    Topics: Carbamazepine; Cell Division; Histamine H1 Antagonists; Humans; Lithium; Neoplasms; Remission, Spont

1995
The treatment of intractable pain.
    The Practitioner, 1975, Volume: 215, Issue:1288

    Topics: Acupuncture Therapy; Analgesics; Analgesics, Opioid; Carbamazepine; Cordotomy; Electric Stimulation

1975
Psychotropic agents in the management of chronic pain.
    Journal of human stress, 1978, Volume: 4, Issue:2

    Topics: Antidepressive Agents, Tricyclic; Carbamazepine; Humans; Neoplasms; Neuralgia; Pain, Intractable; Ph

1978
Rectal doxepin and carbamazepine therapy in patients with cancer.
    The New England journal of medicine, 1992, Oct-29, Volume: 327, Issue:18

    Topics: Administration, Rectal; Carbamazepine; Doxepin; Humans; Neoplasms

1992
Tic douloureux in Rochester, Minnesota, 1945-1969.
    Neurology, 1972, Volume: 22, Issue:9

    Topics: Adult; Age Factors; Aged; Analgesics; Carbamazepine; Ethanol; Female; Follow-Up Studies; Humans; Hyp

1972
Surgical management of pain in cancer of the head and neck.
    The Surgical clinics of North America, 1973, Volume: 53, Issue:1

    Topics: Alcohols; Autonomic Nerve Block; Carbamazepine; Chlorpromazine; Cranial Nerves; Gastrostomy; Head; H

1973