carbamazepine has been researched along with Microcephaly in 7 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Microcephaly: A congenital abnormality in which the CEREBRUM is underdeveloped, the fontanels close prematurely, and, as a result, the head is small. (Desk Reference for Neuroscience, 2nd ed.)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our objective was to evaluate the patterns of malformations in children exposed in utero to phenytoin (DPH) and carbamazepine (CBZ) monotherapy, and to compare them prospectively with matched mother-child pairs exposed to nonteratogens, and to separate the effects of antiepileptic drugs (AEDs) from those of epilepsy by collecting groups of untreated epileptics and those treated with DPH and CBZ for conditions other than epilepsy." | 9.08 | Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications. ( Chitayat, D; Farkas, LD; Koren, G; Nulman, I; Scolnik, D, 1997) |
| "Our objective was to evaluate the patterns of malformations in children exposed in utero to phenytoin (DPH) and carbamazepine (CBZ) monotherapy, and to compare them prospectively with matched mother-child pairs exposed to nonteratogens, and to separate the effects of antiepileptic drugs (AEDs) from those of epilepsy by collecting groups of untreated epileptics and those treated with DPH and CBZ for conditions other than epilepsy." | 5.08 | Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications. ( Chitayat, D; Farkas, LD; Koren, G; Nulman, I; Scolnik, D, 1997) |
| " Fifty-two children had been exposed to phenytoin monotherapy, 19 to carbamazepine monotherapy, 27 to drug combinations including barbiturates, 29 to other drug combinations, and 17 children had not been exposed to antiepileptic drugs (AEDs) during pregnancy." | 3.68 | Head circumference in children of epileptic mothers: contributions of drug exposure and genetic background. ( Bardy, AH; Gaily, EK; Granström, ML; Hiilesmaa, VK, 1990) |
| "We report an infant with moyamoya disease and recurrent stroke presenting 10 months after diagnosis (at age 18 months), and discuss the outcome of nonsurgical medical management." | 1.38 | Medical management of moyamoya disease and recurrent stroke in an infant with Majewski osteodysplastic primordial dwarfism type II (MOPD II). ( Alanay, Y; Boduroğlu, K; Cetin, M; Haliloğlu, G; Kılıç, E; Oğuz, KK; Unal, S; Utine, E, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Awa, HD | 1 |
| Chelo, D | 1 |
| Kinkela, MN | 1 |
| Ndombo, PO | 1 |
| Kılıç, E | 1 |
| Utine, E | 1 |
| Unal, S | 1 |
| Haliloğlu, G | 1 |
| Oğuz, KK | 1 |
| Cetin, M | 1 |
| Boduroğlu, K | 1 |
| Alanay, Y | 1 |
| Nulman, I | 1 |
| Scolnik, D | 1 |
| Chitayat, D | 1 |
| Farkas, LD | 1 |
| Koren, G | 1 |
| Hashimoto, LN | 1 |
| Bass, WT | 1 |
| Green, GA | 1 |
| Werner, AL | 1 |
| Reagan, TJ | 1 |
| Janz, D | 1 |
| Gaily, EK | 1 |
| Granström, ML | 1 |
| Hiilesmaa, VK | 1 |
| Bardy, AH | 1 |
| Majkowski, J | 1 |
| Danneberg, P | 1 |
| Knappen, F | 1 |
| Sersen, EA | 1 |
1 review available for carbamazepine and Microcephaly
| Article | Year |
|---|---|
The teratogenic risk of antiepileptic drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anencephaly; Anti-Anxiety Agents; Anticonvulsa | 1975 |
1 trial available for carbamazepine and Microcephaly
| Article | Year |
|---|---|
Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications.
Topics: Adult; Carbamazepine; Cohort Studies; Craniofacial Abnormalities; Epilepsy; Female; Fingers; Humans; | 1997 |
5 other studies available for carbamazepine and Microcephaly
| Article | Year |
|---|---|
[Patent rickets disclosed by loss of convulsion control in a boy with cerebral palsy].
Topics: Anticonvulsants; Calcium; Carbamazepine; Cerebral Palsy; Child, Preschool; Diazepam; Epilepsy; Human | 2013 |
Medical management of moyamoya disease and recurrent stroke in an infant with Majewski osteodysplastic primordial dwarfism type II (MOPD II).
Topics: Antigens; Carbamazepine; Dwarfism; Female; Fetal Growth Retardation; Heparin, Low-Molecular-Weight; | 2012 |
Radial microbrain form of micrencephaly: possible association with carbamazepine.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Male; Microcephaly; Pregnancy; Preg | 1999 |
Head circumference in children of epileptic mothers: contributions of drug exposure and genetic background.
Topics: Adult; Anticonvulsants; Carbamazepine; Child, Preschool; Epilepsy; Female; Humans; Intelligence Test | 1990 |
Differences in antiepileptic drug efficacy in hippocampally kindled normal and microcephalic rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Evaluation, Preclinical; Elect | 1986 |