carbamazepine has been researched along with MELAS Syndrome in 2 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report on a 38-year-old woman with MELAS presenting with multifocal CPSE and periodic lateralized epileptiform discharges (PLEDs) on EEG during her first strokelike episode." | 1.33 | "Erratic" complex partial status epilepticus as a presenting feature of MELAS. ( Corda, D; Deiana, GA; Rosati, G; Sechi, G, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Corda, D | 1 |
| Rosati, G | 1 |
| Deiana, GA | 1 |
| Sechi, G | 1 |
| Majamaa, K | 1 |
| Rusanen, H | 1 |
| Remes, AM | 1 |
| Pyhtinen, J | 1 |
| Hassinen, IE | 1 |
2 other studies available for carbamazepine and MELAS Syndrome
| Article | Year |
|---|---|
"Erratic" complex partial status epilepticus as a presenting feature of MELAS.
Topics: Adult; Anticonvulsants; Carbamazepine; Diazepam; Electroencephalography; Female; Humans; MELAS Syndr | 2006 |
Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome.
Topics: Aged; Anticonvulsants; Carbamazepine; Cells, Cultured; Cerebrovascular Disorders; Epilepsy; Fibrobla | 1996 |