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carbamazepine and Liver Failure

carbamazepine has been researched along with Liver Failure in 5 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"To the best of our knowledge, this is the first published case report implicating carbamazepine as the cause of anemia associated with bone marrow hypercellularity and dyserythropoietic changes, instead of hypocellularity and reduction of erythroid precursors."7.70Severe multisystemic hypersensitivity reaction to carbamazepine including dyserythropoietic anemia. ( Corrocher, R; Girelli, DG; Lombardi, SM, 1999)
"To the best of our knowledge, this is the first published case report implicating carbamazepine as the cause of anemia associated with bone marrow hypercellularity and dyserythropoietic changes, instead of hypocellularity and reduction of erythroid precursors."3.70Severe multisystemic hypersensitivity reaction to carbamazepine including dyserythropoietic anemia. ( Corrocher, R; Girelli, DG; Lombardi, SM, 1999)
"The carbamazepine treatment was stopped and laboratory parameters improved."1.34[Carbamazepine hepatoxicity--a case report]. ( Gawlikowski, T; Hydzik, P, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bain, BJ1
Gawlikowski, T1
Hydzik, P1
Young, CR1
Mazure, CM1
Haase, MR1
Lombardi, SM1
Girelli, DG1
Corrocher, R1

Other Studies

5 other studies available for carbamazepine and Liver Failure

ArticleYear
Reactive lymphocytes in an allergic drug reaction.
    American journal of hematology, 2019, Volume: 94, Issue:12

    Topics: Adult; Anticonvulsants; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Epilepsy; Female; Huma

2019
[Carbamazepine hepatoxicity--a case report].
    Przeglad lekarski, 2007, Volume: 64, Issue:4-5

    Topics: Adolescent; Carbamazepine; Chemical and Drug Induced Liver Injury; Epilepsy; Hepatitis B Surface Ant

2007
Fulminant hepatic failure from acetaminophen in an anorexic patient treated with carbamazepine.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:11

    Topics: Acetaminophen; Adolescent; Anorexia Nervosa; Carbamazepine; Drug Overdose; Drug Synergism; Drug Ther

1998
Carbamazepine-induced hepatorenal failure in a child.
    Pharmacotherapy, 1999, Volume: 19, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Child; Humans; Liver Failure; Male; Renal Insufficiency

1999
Severe multisystemic hypersensitivity reaction to carbamazepine including dyserythropoietic anemia.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:5

    Topics: Aged; Anemia; Anticonvulsants; Carbamazepine; Cell Size; Dermatitis, Exfoliative; Drug Hypersensitiv

1999