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carbamazepine and Liver Dysfunction

carbamazepine has been researched along with Liver Dysfunction in 18 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Research Excerpts

ExcerptRelevanceReference
" Carbamazepine (CBZ), an antiepileptic medication, is known to modulate hepatic fibrosis and hepatocellular injury in a variety of liver diseases."4.12Carbamazepine mitigates parenteral nutrition-associated liver disease in a novel ambulatory piglet model. ( Armstrong, A; Hutchinson, C; Jain, AK; Jain, S; Krebs, J; Manithody, C; Murali, V; Nagarapu, A; Roenker, J; Samaddar, A; Song, E; van Nispen, J; Voigt, M, 2022)
"Anticonvulsant therapy was among the first areas to benefit from clinical pharmacokinetic studies."2.35Clinical pharmacokinetics of anticonvulsants. ( Dam, M; Hvidberg, EF, 1976)
"Acetic acid is an organic acid that can be used in the food industry, which normally has an insignificant rate of adverse reactions when used rationally."1.91Lethal toxicity induced by combined ingestion of dietary acetic acid and carbamazepine. ( Chitescu, C; Dragostin, OM; Fulga, A; Fulga, I; Irimia, I; Pîrăianu, A; Stamate, E, 2023)
"We present a female with seizures one month after delivery who had borderline elevated liver enzymes prior to the initiation of OXC treatment."1.39Acute oxcarbazepine-induced hepatotoxicity in a patient susceptible to developing drug-induced liver injury. ( Bielen, A; Bielen, I; Marusić, M; Planjar-Prvan, M; Sruk, A, 2013)
"Her ageusia was related to a variety of causes including an unbalanced diet, administration of the anti-epileptic drug, carbamazepine and psychological factors."1.29Case of ageusia from a variety of causes. ( Deguchi, K; Furuta, S; Imakiire, T; Ohyama, M, 1996)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19907 (38.89)18.7374
1990's5 (27.78)18.2507
2000's1 (5.56)29.6817
2010's3 (16.67)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Song, E1
Nagarapu, A1
van Nispen, J1
Armstrong, A1
Manithody, C1
Murali, V1
Voigt, M1
Samaddar, A1
Hutchinson, C1
Jain, S1
Roenker, J1
Krebs, J1
Jain, AK1
Fulga, I1
Dragostin, OM1
Chitescu, C1
Irimia, I1
Pîrăianu, A1
Stamate, E1
Fulga, A1
Planjar-Prvan, M1
Bielen, A1
Sruk, A1
Marusić, M1
Bielen, I1
Wilson, AA1
Ying, L1
Liesa, M1
Segeritz, CP1
Mills, JA1
Shen, SS1
Jean, J1
Lonza, GC1
Liberti, DC1
Lang, AH1
Nazaire, J1
Gower, AC1
Müeller, FJ1
Mehta, P1
Ordóñez, A1
Lomas, DA1
Vallier, L1
Murphy, GJ1
Mostoslavsky, G1
Spira, A1
Shirihai, OS1
Ramirez, MI1
Gadue, P1
Kotton, DN1
Perlmutter, DH1
Bruni, J1
Albright, PS1
Asconapé, JJ1
Penry, JK1
Soffer, EE1
Taylor, RJ1
Bertram, PD1
Haggitt, RC1
Levinson, MJ1
Deguchi, K1
Furuta, S1
Imakiire, T1
Ohyama, M1
Hemingway, C1
Leary, M1
Riordan, G1
Schlegal, B1
Walker, K1
Yamaki, M1
Yoshida, I1
Kaspar, U1
Hvidberg, EF1
Dam, M1
Hooper, WD1
Dubetz, DK1
Bochner, F1
Cotter, LM1
Smith, GA1
Eadie, MJ1
Tyrer, JH1
Foster, GR1
Goldin, RD1
Freeth, CJ1
Nieman, E1
Oliveira, DB1
Askmark, H1
Wiholm, BE1
Hadzić, N1
Portmann, B1
Davies, ET1
Mowat, AP1
Mieli-Vergani, G1
Olsson, R1
Zettergren, L1

Reviews

5 reviews available for carbamazepine and Liver Dysfunction

ArticleYear
Alpha-1-antitrypsin deficiency: importance of proteasomal and autophagic degradative pathways in disposal of liver disease-associated protein aggregates.
    Annual review of medicine, 2011, Volume: 62

    Topics: alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Animals; Autophagy; Carbamazepine; Cell Transfo

2011
The clinical pharmacology of antiepileptic drugs.
    Clinical neuropharmacology, 1984, Volume: 7, Issue:1

    Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Hal

1984
Use of antiepileptic drugs in the presence of liver and kidney diseases: a review.
    Epilepsia, 1982, Volume: 23 Suppl 1

    Topics: Anticonvulsants; Carbamazepine; Epilepsy; Half-Life; Humans; Kidney Diseases; Kinetics; Liver Diseas

1982
[Diphenylhydantoin. Metabolism, pharmacokinetics, interactions and side effects].
    Schweizerische medizinische Wochenschrift, 1976, Jun-05, Volume: 106, Issue:23

    Topics: Anti-Anxiety Agents; Benzodiazepines; Bone and Bones; Bone Marrow; Carbamazepine; Cerebellar Disease

1976
Clinical pharmacokinetics of anticonvulsants.
    Clinical pharmacokinetics, 1976, Volume: 1, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam

1976

Other Studies

13 other studies available for carbamazepine and Liver Dysfunction

ArticleYear
Carbamazepine mitigates parenteral nutrition-associated liver disease in a novel ambulatory piglet model.
    JPEN. Journal of parenteral and enteral nutrition, 2022, Volume: 46, Issue:6

    Topics: Animals; Carbamazepine; Ki-67 Antigen; Liver Diseases; Parenteral Nutrition; Swine

2022
Lethal toxicity induced by combined ingestion of dietary acetic acid and carbamazepine.
    Drug and chemical toxicology, 2023, Volume: 46, Issue:4

    Topics: Acetic Acid; Carbamazepine; Eating; Female; Humans; Liver Diseases; Middle Aged

2023
Acute oxcarbazepine-induced hepatotoxicity in a patient susceptible to developing drug-induced liver injury.
    Collegium antropologicum, 2013, Volume: 37, Issue:1

    Topics: Acridines; Carbamazepine; Chemical and Drug Induced Liver Injury; Delivery, Obstetric; Female; Human

2013
Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells.
    Stem cell reports, 2015, May-12, Volume: 4, Issue:5

    Topics: Alleles; alpha 1-Antitrypsin; Autophagy; Carbamazepine; Cell Differentiation; Cells, Cultured; DNA M

2015
Carbamazepine-induced liver injury.
    Southern medical journal, 1983, Volume: 76, Issue:5

    Topics: Adult; Biopsy; Carbamazepine; Chemical and Drug Induced Liver Injury; Female; Hepatitis; Humans; Liv

1983
Case of ageusia from a variety of causes.
    The Journal of laryngology and otology, 1996, Volume: 110, Issue:6

    Topics: Adult; Ageusia; Anorexia; Carbamazepine; Chemical and Drug Induced Liver Injury; Female; Humans; Liv

1996
The effect of carbamazepine and sodium valproate on the blood and serum values of children from a third-world environment.
    Journal of child neurology, 1999, Volume: 14, Issue:11

    Topics: Adolescent; Anemia; Anticonvulsants; Black People; Carbamazepine; Child; Child, Preschool; Developin

1999
[A case of acute renal failure and liver dysfunction induced by carbamazepine(CBZ)].
    Nihon Jinzo Gakkai shi, 2001, Volume: 43, Issue:4

    Topics: Acute Kidney Injury; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Female;

2001
Plasma protein binding of carbamazepine.
    Clinical pharmacology and therapeutics, 1975, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Aged; Blood Proteins; Carbamazepine; Erythrocytes; Female; Humans; Kidney Disease

1975
Liver damage in long-term anticonvulsant therapy: a serological and histological study.
    The Quarterly journal of medicine, 1991, Volume: 79, Issue:288

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Combinatio

1991
Epidemiology of adverse reactions to carbamazepine as seen in a spontaneous reporting system.
    Acta neurologica Scandinavica, 1990, Volume: 81, Issue:2

    Topics: Age Factors; Carbamazepine; Chemical and Drug Induced Liver Injury; Epilepsy; Female; Hematologic Di

1990
Acute liver failure induced by carbamazepine.
    Archives of disease in childhood, 1990, Volume: 65, Issue:3

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Child; Female; Humans; Liver; Liver Diseases;

1990
Anticonvulsant-induced liver damage.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:5

    Topics: Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Clonazepam; Humans; L

1988