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carbamazepine and Leukocytopenia

carbamazepine has been researched along with Leukocytopenia in 31 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Research Excerpts

ExcerptRelevanceReference
"A rare case of carbamazepine-induced leucopenia and thrombocytopenia complicated by Henoch-Schönlein purpura (HSP) symptoms is presented."7.68Carbamazepine-induced thrombocytopenia and leucopenia complicated by Henoch-Schönlein purpura symptoms. ( Igarashi, J; Ishimoto, K; Kaneko, K; Niijima, S; Suzuki, Y; Yabuta, K, 1993)
"One hundred seventy-six children treated with carbamazepine for epilepsy were monitored over a 12-month period to determine the effects of carbamazepine on the hematologic system."7.67Hematologic monitoring in children with epilepsy treated with carbamazepine. ( Evans, OB; Gay, H; Parks, B; Swisher, A, 1989)
"A case of carbamazepine-induced leukopenia with subsequent successful carbamazepine management is presented."7.67Successful treatment course with carbamazepine despite initial significant leukopenia: case report. ( Regan, WM, 1987)
"Carbamazepine is gaining recognition as a valuable drug in the treatment of patients with bipolar disorders who fail to respond to lithium."7.67The long-term management of bipolar disorders with lithium, carbamazepine, and antidepressants. ( Fawcett, J; Kravitz, HM, 1985)
"We have reported the first case of severe leukopenia, complicated by infection, associated with the use of carbamazepine."7.66Severe leukopenia secondary to carbamazepine administration. ( Gerber, JG; Nies, AS; Stiles, G, 1979)
"Carbamazepine is a drug commonly prescribed by medical and dental practitioners for the treatment of trigeminal neuralgia."3.70A severe reaction to carbamazepine: consequences for patient monitoring. ( Edmondson, HD; Hamburger, J; Neale, SJ, 1998)
"The purpose of this study was to determine the occurrence of leukopenia and other blood dyscrasias associated with psychiatric use of carbamazepine and valproate."3.69Blood dyscrasias with carbamazepine and valproate: a pharmacoepidemiological study of 2,228 patients at risk. ( Baldessarini, RJ; Castillo, J; Kando, JC; Tohen, M; Zarate, C, 1995)
"A rare case of carbamazepine-induced leucopenia and thrombocytopenia complicated by Henoch-Schönlein purpura (HSP) symptoms is presented."3.68Carbamazepine-induced thrombocytopenia and leucopenia complicated by Henoch-Schönlein purpura symptoms. ( Igarashi, J; Ishimoto, K; Kaneko, K; Niijima, S; Suzuki, Y; Yabuta, K, 1993)
"One hundred seventy-six children treated with carbamazepine for epilepsy were monitored over a 12-month period to determine the effects of carbamazepine on the hematologic system."3.67Hematologic monitoring in children with epilepsy treated with carbamazepine. ( Evans, OB; Gay, H; Parks, B; Swisher, A, 1989)
"A case of carbamazepine-induced leukopenia with subsequent successful carbamazepine management is presented."3.67Successful treatment course with carbamazepine despite initial significant leukopenia: case report. ( Regan, WM, 1987)
"Appropriate use of carbamazepine for the treatment of epilepsy is based on correct identification of the patient's seizure type."3.67How to initiate and maintain carbamazepine therapy in children and adults. ( Porter, RJ, 1987)
"Carbamazepine is gaining recognition as a valuable drug in the treatment of patients with bipolar disorders who fail to respond to lithium."3.67The long-term management of bipolar disorders with lithium, carbamazepine, and antidepressants. ( Fawcett, J; Kravitz, HM, 1985)
"A case is reported of a 13-year-old girl who had an illness initially thought to be toxic shock syndrome but subsequently noted to be a toxic reaction to the anticonvulsant, carbamazepine."3.66Pseudo-toxic-shock syndrome due to a drug reaction. ( Bernstein, DI; Carney, J; Cherry, JD, 1983)
"We have reported the first case of severe leukopenia, complicated by infection, associated with the use of carbamazepine."3.66Severe leukopenia secondary to carbamazepine administration. ( Gerber, JG; Nies, AS; Stiles, G, 1979)
"Carbamazepine is a commonly used anticonvulsant agent; however, it has been linked with various blood cell abnormalities."2.72Folic acid supplementation reduces the development of some blood cell abnormalities in children receiving carbamazepine. ( Asadi-Pooya, AA; Ghetmiri, E, 2006)
"Rare, serious adverse effects of antiepileptic drugs (AEDs) include hepatotoxicity and bone marrow suppression."2.38Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy. ( Wyllie, E; Wyllie, R, 1991)
"Carbamazepine was found to cause statistically significant, but clinically insubstantial, decreases in white blood cell indexes."1.27Hematological effects of carbamazepine in patients with affective illness. ( Joffe, RT; Post, RM; Roy-Byrne, PP; Uhde, TW, 1985)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199019 (61.29)18.7374
1990's7 (22.58)18.2507
2000's5 (16.13)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yeh, YW1
Wang, TY1
Huang, CC1
Chen, YC1
Milia, A1
Pilia, G1
Mascia, MG1
Moller, J1
Cocco, E1
Marrosu, MG1
Cohen, Y1
Rund, D1
Moualem, E1
Kalish, Y1
Polliack, A1
Asadi-Pooya, AA1
Ghetmiri, E1
Livingston, S1
Pauli, LL1
Berman, W1
Bernstein, DI1
Carney, J1
Cherry, JD1
Hart, RG1
Easton, JD1
Tohen, M1
Castillo, J1
Baldessarini, RJ1
Zarate, C1
Kando, JC1
Kaneko, K1
Igarashi, J1
Suzuki, Y1
Niijima, S1
Ishimoto, K1
Yabuta, K1
Spickett, GP1
Gompels, MM1
Saunders, PW1
Neale, SJ1
Hamburger, J1
Edmondson, HD1
Ryan, M1
Adams, AG1
Larive, LL1
Vaĭntrub, MIa1
Shapiro, IuL1
Rylance, GW1
Moreland, TA1
Gerber, JG1
Stiles, G1
Nies, AS1
Wyllie, E1
Wyllie, R1
Kramlinger, KG1
Post, RM3
Sheehan, JD1
Shelley, RK1
Joffe, RT2
Evans, OB1
Gay, H1
Swisher, A1
Parks, B1
Evans, RW1
Gualtieri, CT1
Regan, WM1
Porter, RJ1
Brewerton, TD1
Fawcett, J1
Kravitz, HM1
Minich, PJ1
Young, WA1
Roy-Byrne, PP1
Uhde, TW1
Cereghino, JJ1
Brock, JT1
Van Meter, JC1
Penry, JK1
Smith, LD1
White, BG1
Crill, WE1
Roedenbeck, SD1
Santos, J1
Killian, JM1

Reviews

3 reviews available for carbamazepine and Leukocytopenia

ArticleYear
Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy.
    Epilepsia, 1991, Volume: 32 Suppl 5

    Topics: Anemia, Aplastic; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Monit

1991
Carbamazepine: a neuropsychological and psychiatric profile.
    Clinical neuropharmacology, 1985, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Attention; Blood Proteins; Carbamazepine; Child; Cognition; Epilepsy; Female; Hum

1985
Drugs 5 years later: carbamazepine.
    Annals of internal medicine, 1973, Volume: 79, Issue:6

    Topics: Agranulocytosis; Anemia, Aplastic; Anticonvulsants; Bone Marrow; Bone Marrow Cells; Carbamazepine; D

1973

Trials

3 trials available for carbamazepine and Leukocytopenia

ArticleYear
Folic acid supplementation reduces the development of some blood cell abnormalities in children receiving carbamazepine.
    Epilepsy & behavior : E&B, 2006, Volume: 8, Issue:1

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Dietary Supplements; Female; Folic Acid; Hematini

2006
Addition of lithium carbonate to carbamazepine: hematological and thyroid effects.
    The American journal of psychiatry, 1990, Volume: 147, Issue:5

    Topics: Adult; Blood Cell Count; Carbamazepine; Clinical Trials as Topic; Depressive Disorder; Double-Blind

1990
Carbamazepine for epilepsy. A controlled prospective evaluation.
    Neurology, 1974, Volume: 24, Issue:5

    Topics: Adult; Blood Cell Count; Bone Marrow Diseases; Carbamazepine; Clinical Trials as Topic; Electroencep

1974

Other Studies

25 other studies available for carbamazepine and Leukocytopenia

ArticleYear
Late-onset hypersensitivity reaction with leukopenia and thrombocytopenia induced by oxcarbazepine treatment in a patient with schizoaffective disorder.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:4

    Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Diagnostic and Statistical Manual of Mental Disord

2008
Oxcarbazepine-induced leukopenia.
    The Journal of neuropsychiatry and clinical neurosciences, 2008,Fall, Volume: 20, Issue:4

    Topics: Adult; Anticonvulsants; Blood Cell Count; Carbamazepine; Epilepsies, Partial; Humans; Leukopenia; Ma

2008
Carbamazepine-induced generalized "pseudoleukemia lymphoma"--like syndrome.
    The Israel Medical Association journal : IMAJ, 2003, Volume: 5, Issue:6

    Topics: Adult; Anticonvulsants; Biopsy; Carbamazepine; Drug Hypersensitivity; Epilepsy, Tonic-Clonic; Female

2003
Carbamazepine (Tegretol) in epilepsy. Nine year follow-up study with special emphasis on untoward reactions.
    Diseases of the nervous system, 1974, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Carbamazepine; Child; Diplopia; Drug Overd

1974
Pseudo-toxic-shock syndrome due to a drug reaction.
    Clinical pediatrics, 1983, Volume: 22, Issue:7

    Topics: Adolescent; Carbamazepine; Diagnostic Errors; Drug Eruptions; Eosinophilia; Female; Fever; Humans; L

1983
Carbamazepine and hematological monitoring.
    Annals of neurology, 1982, Volume: 11, Issue:3

    Topics: Adolescent; Anemia; Anemia, Aplastic; Carbamazepine; Female; Hematologic Diseases; Humans; Leukopeni

1982
Blood dyscrasias with carbamazepine and valproate: a pharmacoepidemiological study of 2,228 patients at risk.
    The American journal of psychiatry, 1995, Volume: 152, Issue:3

    Topics: Adolescent; Adult; Anemia; Carbamazepine; Depressive Disorder; Desipramine; Drug Therapy, Combinatio

1995
Carbamazepine-induced thrombocytopenia and leucopenia complicated by Henoch-Schönlein purpura symptoms.
    European journal of pediatrics, 1993, Volume: 152, Issue:9

    Topics: Bone Marrow; Carbamazepine; Child; Depression, Chemical; Drug Hypersensitivity; Female; Humans; IgA

1993
Hypogammaglobulinaemia with absent B lymphocytes and agranulocytosis after carbamazepine treatment.
    Journal of neurology, neurosurgery, and psychiatry, 1996, Volume: 60, Issue:4

    Topics: Agranulocytosis; Anticonvulsants; B-Lymphocytes; Carbamazepine; Dysgammaglobulinemia; Humans; IgA De

1996
A severe reaction to carbamazepine: consequences for patient monitoring.
    British dental journal, 1998, Sep-26, Volume: 185, Issue:6

    Topics: Adult; Analgesics, Non-Narcotic; Carbamazepine; Drug Hypersensitivity; Drug Monitoring; Female; Huma

1998
Hyponatremia and leukopenia associated with oxcarbazepine following carbamazepine therapy.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2001, Sep-01, Volume: 58, Issue:17

    Topics: Anticonvulsants; Carbamazepine; Female; Humans; Hyponatremia; Leukopenia; Middle Aged; Oxcarbazepine

2001
[Neutropenia in epilepsy patients].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979, Volume: 79, Issue:3

    Topics: Adolescent; Adult; Agranulocytosis; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epile

1979
Carbamazepine for childhood seizures.
    Developmental medicine and child neurology, 1978, Volume: 20, Issue:4

    Topics: Age Factors; Carbamazepine; Child; Humans; Kinetics; Leukopenia; Seizures

1978
Severe leukopenia secondary to carbamazepine administration.
    Southern medical journal, 1979, Volume: 72, Issue:1

    Topics: Adult; Carbamazepine; Humans; Leukopenia; Male; Staphylococcal Infections

1979
Leucopenia secondary to carbamazepine despite concurrent lithium treatment.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 157

    Topics: Adult; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; Humans; Leukocyte Count; Leukopen

1990
Lithium and carbamazepine-induced agranulocytosis.
    The American journal of psychiatry, 1989, Volume: 146, Issue:3

    Topics: Agranulocytosis; Carbamazepine; Humans; Leukocyte Count; Leukopenia; Lithium; Lithium Carbonate; Neu

1989
Hematologic monitoring in children with epilepsy treated with carbamazepine.
    Journal of child neurology, 1989, Volume: 4, Issue:4

    Topics: Agranulocytosis; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Follow-Up Studies; Humans

1989
Successful treatment course with carbamazepine despite initial significant leukopenia: case report.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:8

    Topics: Aged; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans;

1987
How to initiate and maintain carbamazepine therapy in children and adults.
    Epilepsia, 1987, Volume: 28 Suppl 3

    Topics: Adult; Anemia, Aplastic; Carbamazepine; Child; Drug Administration Schedule; Epilepsy; Humans; Leuko

1987
Lithium counteracts carbamazepine-induced leukopenia while increasing its therapeutic effect.
    Biological psychiatry, 1986, Volume: 21, Issue:7

    Topics: Adult; Bipolar Disorder; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination;

1986
The long-term management of bipolar disorders with lithium, carbamazepine, and antidepressants.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:2

    Topics: Anemia; Antidepressive Agents, Tricyclic; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination

1985
Severe hematologic and neurologic reaction to carbamazepine.
    Canadian Medical Association journal, 1985, May-01, Volume: 132, Issue:9

    Topics: Aged; Agranulocytosis; Carbamazepine; Central Nervous System Diseases; Hematologic Diseases; Humans;

1985
Hematological effects of carbamazepine in patients with affective illness.
    The American journal of psychiatry, 1985, Volume: 142, Issue:10

    Topics: Adult; Anemia; Anemia, Aplastic; Bipolar Disorder; Carbamazepine; Diagnosis, Differential; Erythrocy

1985
[Tegretol in the treatment of severe infantile convulsions].
    Revista de neuro-psiquiatria, 1967, Volume: 30, Issue:3

    Topics: Carbamazepine; Child; Child, Preschool; Dibenzazepines; Female; Humans; Infant; Infant, Newborn; Inf

1967
Tegretol in trigeminal neuralgia with special reference to hematopoietic side effects.
    Headache, 1969, Volume: 9, Issue:1

    Topics: Adult; Aged; Carbamazepine; Dibenzazepines; Female; Humans; Leukopenia; Male; Middle Aged; Skin Mani

1969