carbamazepine has been researched along with Lesch-Nyhan Syndrome in 3 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Lesch-Nyhan Syndrome: An inherited disorder transmitted as a sex-linked trait and caused by a deficiency of an enzyme of purine metabolism; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE. Affected individuals are normal in the first year of life and then develop psychomotor retardation, extrapyramidal movement disorders, progressive spasticity, and seizures. Self-destructive behaviors such as biting of fingers and lips are seen frequently. Intellectual impairment may also occur but is typically not severe. Elevation of uric acid in the serum leads to the development of renal calculi and gouty arthritis. (Menkes, Textbook of Child Neurology, 5th ed, pp127)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SJ | 1 |
| Sohn, YB | 1 |
| Park, SW | 1 |
| Jin, DK | 1 |
| Paik, KH | 1 |
| Robey, KL | 1 |
| Reck, JF | 1 |
| Giacomini, KD | 1 |
| Barabas, G | 1 |
| Eddey, GE | 1 |
| Roach, ES | 1 |
| Delgado, M | 1 |
| Anderson, L | 1 |
| Iannaccone, ST | 1 |
| Burns, DK | 1 |
3 other studies available for carbamazepine and Lesch-Nyhan Syndrome
| Article | Year |
|---|---|
Chronic peritoneal dialysis in a 4-year-old boy with Lesch-Nyhan disease.
Topics: Allopurinol; Carbamazepine; Child, Preschool; DNA Mutational Analysis; Erythrocytes; Family Health; | 2009 |
Modes and patterns of self-mutilation in persons with Lesch-Nyhan disease.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Chromosomes, Human, X; D | 2003 |
Carbamazepine trial for Lesch-Nyhan self-mutilation.
Topics: Adolescent; Analgesics, Non-Narcotic; Biopsy; Carbamazepine; Child; Child, Preschool; Humans; Lesch- | 1996 |