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carbamazepine and Kidney Diseases

carbamazepine has been researched along with Kidney Diseases in 18 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"We report a patient in whom hypersensitivity to carbamazepine presented with generalized erythroderma, a severe leukemoid reaction, eosinophilia, hyponatremia, and renal failure."7.67Hypersensitivity to carbamazepine presenting with a leukemoid reaction, eosinophilia, erythroderma, and renal failure. ( Boggild, M; Pye, IF; Ray-Chaudhuri, K, 1989)
"A man with resistant lithium-induced nephrogenic diabetes insipidus and affective psychosis was successfully treated with carbamazepine."7.66Treatment of resistant lithium-induced nephrogenic diabetes insipidus and schizoaffective psychosis with carbamazepine. ( Brooks, SC; Lessin, BE, 1983)
"We report a patient in whom hypersensitivity to carbamazepine presented with generalized erythroderma, a severe leukemoid reaction, eosinophilia, hyponatremia, and renal failure."3.67Hypersensitivity to carbamazepine presenting with a leukemoid reaction, eosinophilia, erythroderma, and renal failure. ( Boggild, M; Pye, IF; Ray-Chaudhuri, K, 1989)
"A man with resistant lithium-induced nephrogenic diabetes insipidus and affective psychosis was successfully treated with carbamazepine."3.66Treatment of resistant lithium-induced nephrogenic diabetes insipidus and schizoaffective psychosis with carbamazepine. ( Brooks, SC; Lessin, BE, 1983)
"Oxcarbazepine (OCBZ) is a new antiepileptic drug (AED) structurally related to carbamazepine (CBZ) but differing in several important aspects, notably metabolism and induction of metabolic pathways."2.39Clinical pharmacology and pharmacokinetics of oxcarbazepine. ( Dieterle, W; Flesch, G; Lloyd, P, 1994)
"Anticonvulsant therapy was among the first areas to benefit from clinical pharmacokinetic studies."2.35Clinical pharmacokinetics of anticonvulsants. ( Dam, M; Hvidberg, EF, 1976)
" Our data suggest that valproate has adverse effects on renal tubular functions."1.42Does nephrotoxicity exist in pediatric epileptic patients on valproate or carbamazepine therapy? ( Buyan, N; Demir, E; Gücüyener, K; Gülbahar, Ö; Gürkaş, E; Havali, C; Serdaroğlu, A; Yılmaz, Ü, 2015)
" The apparent elimination half-life of the monohydroxy-metabolite [19 (SD 3) h] in these patients was about twice that in healthy subjects."1.29The effect of renal impairment on the pharmacokinetics of oxcarbazepine and its metabolites. ( Aldigier, JC; Darragon, T; Godbillon, J; Hillion, D; Jungers, P; Kourilsky, O; Lecaillon, JB; Menard, F; Meyer, P; Rouan, MC, 1994)
" Experts note that adverse drug reactions (ADRs) have become the 'greatest imitator' of disease in clinical medicine."1.28Distinguishing drug toxicity syndromes from medical diseases: a QMR computer-based approach. ( Mabry, ME; Miller, RA, 1991)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19908 (44.44)18.7374
1990's4 (22.22)18.2507
2000's1 (5.56)29.6817
2010's4 (22.22)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Avdeef, A1
Tam, KY1
Chen, J1
Bai, L1
He, Y1
Hamed, SA1
Rageh, TA1
Mohamad, AO1
Abou Elnour, SM1
Havali, C1
Gücüyener, K1
Buyan, N1
Yılmaz, Ü1
Gürkaş, E1
Gülbahar, Ö1
Demir, E1
Serdaroğlu, A1
Akar, M1
Dilli, D1
Yilmaz, Y1
Erdeve, O1
Oguz, S1
Uras, N1
Dilmen, U1
Brooks, SC1
Lessin, BE1
Bruni, J1
Albright, PS1
Asconapé, JJ1
Penry, JK1
Rouan, MC1
Lecaillon, JB1
Godbillon, J1
Menard, F1
Darragon, T1
Meyer, P1
Kourilsky, O1
Hillion, D1
Aldigier, JC1
Jungers, P1
Lloyd, P1
Flesch, G1
Dieterle, W1
Tormey, WP1
Verrotti, A1
Greco, R1
Pascarella, R1
Matera, V1
Morgese, G1
Chiarelli, F1
Hvidberg, EF1
Dam, M1
Hooper, WD1
Dubetz, DK1
Bochner, F1
Cotter, LM1
Smith, GA1
Eadie, MJ1
Tyrer, JH1
Mabry, ME1
Miller, RA1
Ray-Chaudhuri, K1
Pye, IF1
Boggild, M1
De Sousa, RC1
Shibasaki, H1
Tabira, T1
Inoue, N1
Goto, I1
Kuroiwa, Y1

Reviews

5 reviews available for carbamazepine and Kidney Diseases

ArticleYear
The clinical pharmacology of antiepileptic drugs.
    Clinical neuropharmacology, 1984, Volume: 7, Issue:1

    Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Hal

1984
Use of antiepileptic drugs in the presence of liver and kidney diseases: a review.
    Epilepsia, 1982, Volume: 23 Suppl 1

    Topics: Anticonvulsants; Carbamazepine; Epilepsy; Half-Life; Humans; Kidney Diseases; Kinetics; Liver Diseas

1982
Clinical pharmacology and pharmacokinetics of oxcarbazepine.
    Epilepsia, 1994, Volume: 35 Suppl 3

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Antipyrine; Carbamazepine; Child; Cytochrome

1994
Clinical pharmacokinetics of anticonvulsants.
    Clinical pharmacokinetics, 1976, Volume: 1, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam

1976
[Diabetes insipidus--various recent aspects].
    Schweizerische medizinische Wochenschrift, 1974, Jul-27, Volume: 104, Issue:30

    Topics: Animals; Arginine; Carbamazepine; Chlorpropamide; Clofibrate; Cyclic AMP; Diabetes Insipidus; Hypoth

1974

Trials

1 trial available for carbamazepine and Kidney Diseases

ArticleYear
Carbamazepine for painful crises in Fabry's disease.
    Journal of the neurological sciences, 1973, Volume: 18, Issue:1

    Topics: Adult; Carbamazepine; Clinical Trials as Topic; Evaluation Studies as Topic; Glycolipids; Humans; Ki

1973

Other Studies

12 other studies available for carbamazepine and Kidney Diseases

ArticleYear
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological

2010
A possible case of carbamazepine-induced renal phospholipidosis mimicking Fabry disease.
    Clinical and experimental nephrology, 2022, Volume: 26, Issue:3

    Topics: alpha-Galactosidase; Carbamazepine; Fabry Disease; Humans; Kidney; Kidney Diseases; Male; Proteinuri

2022
Renal dysfunctions/injury in adult epilepsy patients treated with carbamazepine or valproate.
    Expert review of clinical pharmacology, 2018, Volume: 11, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Creatinine; Cross-Sectional Studies; Epilepsy; Fe

2018
Does nephrotoxicity exist in pediatric epileptic patients on valproate or carbamazepine therapy?
    Journal of child neurology, 2015, Volume: 30, Issue:3

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Creatinine; Cystatin C; Epi

2015
A case of fetal carbamazepine syndrome with right hemihypoplasia of the entire body.
    Genetic counseling (Geneva, Switzerland), 2012, Volume: 23, Issue:1

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Bone and Bones; Carbamazepine; Congenital Abnormalitie

2012
Treatment of resistant lithium-induced nephrogenic diabetes insipidus and schizoaffective psychosis with carbamazepine.
    The American journal of psychiatry, 1983, Volume: 140, Issue:8

    Topics: Adult; Carbamazepine; Diabetes Insipidus; Humans; Kidney Diseases; Lithium; Lithium Carbonate; Male;

1983
The effect of renal impairment on the pharmacokinetics of oxcarbazepine and its metabolites.
    European journal of clinical pharmacology, 1994, Volume: 47, Issue:2

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Female; Humans; Kidney Diseases; Male; Middle Aged; Oxc

1994
Mechanisms of carbamazepine-induced antidiuresis.
    Journal of neurology, neurosurgery, and psychiatry, 1993, Volume: 56, Issue:5

    Topics: Arginine Vasopressin; Carbamazepine; Female; Humans; Hypernatremia; Kidney Diseases; Male; Osmolar C

1993
Renal tubular function in patients receiving anticonvulsant therapy: a long-term study.
    Epilepsia, 2000, Volume: 41, Issue:11

    Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Follow-Up Studies;

2000
Plasma protein binding of carbamazepine.
    Clinical pharmacology and therapeutics, 1975, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Aged; Blood Proteins; Carbamazepine; Erythrocytes; Female; Humans; Kidney Disease

1975
Distinguishing drug toxicity syndromes from medical diseases: a QMR computer-based approach.
    Computer methods and programs in biomedicine, 1991, Volume: 35, Issue:4

    Topics: Aged; Artificial Intelligence; Brain Diseases; Carbamazepine; Decision Support Techniques; Diagnosis

1991
Hypersensitivity to carbamazepine presenting with a leukemoid reaction, eosinophilia, erythroderma, and renal failure.
    Neurology, 1989, Volume: 39, Issue:3

    Topics: Adult; Carbamazepine; Dermatitis, Exfoliative; Drug Hypersensitivity; Eosinophilia; Female; Humans;

1989