carbamazepine has been researched along with Inflammation in 18 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Irrespective of concomitant administration of enzyme-inducing AEDs, the serum perampanel concentration showed a marked increase in patients with inflammation." | 9.27 | Influence of Inflammation on the Pharmacokinetics of Perampanel. ( Horino, A; Imai, K; Inoue, Y; Kagawa, Y; Nishida, T; Takahashi, Y; Usui, N; Yamamoto, Y, 2018) |
| " In this study, we examined the effects of LEV on neuroinflammation and phagocytic microglia in vivo and in vitro and compared the effects of LEV with those of representative antiepileptic drugs valproate (VPA) and carbamazepine (CBZ)." | 7.91 | Suppressive effects of levetiracetam on neuroinflammation and phagocytic microglia: A comparative study of levetiracetam, valproate and carbamazepine. ( Ishihara, Y; Itoh, K; Matsuo, T; Oguro, A; Taniguchi, R; Vogel, CFA; Yamazaki, T, 2019) |
| "We studied whether peripheral alpha2-adrenergic receptors are involved in the antihyperalgesic effects of oxcarbazepine by examining the effects of yohimbine (selective alpha2-adrenoceptor antagonist), BRL 44408 (selective alpha(2A)-adrenoceptor antagonist), MK-912 (selective alpha2C-adrenoceptor antagonist), and clonidine (alpha2-adrenoceptor agonist) on the antihyperalgesic effect of oxcarbazepine in the rat model of inflammatory pain." | 7.74 | The involvement of peripheral alpha 2-adrenoceptors in the antihyperalgesic effect of oxcarbazepine in a rat model of inflammatory pain. ( Bosković, B; Paranos, SLj; Prostran, MS; Stepanović-Petrović, RM; Tomić, MA; Ugresić, ND; Vucković, SM, 2007) |
| "Irrespective of concomitant administration of enzyme-inducing AEDs, the serum perampanel concentration showed a marked increase in patients with inflammation." | 5.27 | Influence of Inflammation on the Pharmacokinetics of Perampanel. ( Horino, A; Imai, K; Inoue, Y; Kagawa, Y; Nishida, T; Takahashi, Y; Usui, N; Yamamoto, Y, 2018) |
| " In this study, we examined the effects of LEV on neuroinflammation and phagocytic microglia in vivo and in vitro and compared the effects of LEV with those of representative antiepileptic drugs valproate (VPA) and carbamazepine (CBZ)." | 3.91 | Suppressive effects of levetiracetam on neuroinflammation and phagocytic microglia: A comparative study of levetiracetam, valproate and carbamazepine. ( Ishihara, Y; Itoh, K; Matsuo, T; Oguro, A; Taniguchi, R; Vogel, CFA; Yamazaki, T, 2019) |
| "We studied whether peripheral alpha2-adrenergic receptors are involved in the antihyperalgesic effects of oxcarbazepine by examining the effects of yohimbine (selective alpha2-adrenoceptor antagonist), BRL 44408 (selective alpha(2A)-adrenoceptor antagonist), MK-912 (selective alpha2C-adrenoceptor antagonist), and clonidine (alpha2-adrenoceptor agonist) on the antihyperalgesic effect of oxcarbazepine in the rat model of inflammatory pain." | 3.74 | The involvement of peripheral alpha 2-adrenoceptors in the antihyperalgesic effect of oxcarbazepine in a rat model of inflammatory pain. ( Bosković, B; Paranos, SLj; Prostran, MS; Stepanović-Petrović, RM; Tomić, MA; Ugresić, ND; Vucković, SM, 2007) |
| "CNS inflammation is characterized by a disturbance of glial cell functions." | 1.40 | Glia and epilepsy: experimental investigation of antiepileptic drugs in an astroglia/microglia co-culture model of inflammation. ( Dambach, H; Faustmann, PM; Haase, CG; Hinkerohe, D; Hufnagel, A; Moinfar, Z; Prochnow, N; Stienen, MN, 2014) |
| " Compound 4 had good efficacy (52% and 41% reversal of allodynia at 2 and 4h post-dose, respectively) in the Chung rat spinal nerve ligation (SNL) model of neuropathic pain when dosed orally at 10mg/kg." | 1.35 | Imidazopyridines: a novel class of hNav1.7 channel blockers. ( Abbadie, C; Dean, B; Duffy, JL; Felix, JP; Garcia, ML; Hoyt, SB; Jochnowitz, N; Kaczorowski, GJ; Karanam, BV; Li, X; London, C; Lyons, KA; Martin, WJ; McGowan, E; Parsons, WH; Priest, BT; Smith, MM; Tschirret-Guth, R; Warren, VA; Williams, BS, 2008) |
| "Bicuculline alone did not produce an intrinsic effect in the paw-pressure test." | 1.35 | GABAergic mechanisms are involved in the antihyperalgesic effects of carbamazepine and oxcarbazepine in a rat model of inflammatory hyperalgesia. ( Bosković, B; Kocev, N; Prostran, MS; Stepanović-Petrović, RM; Tomić, MA; Ugresić, ND; Vucković, SM, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 8 (44.44) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| London, C | 1 |
| Hoyt, SB | 1 |
| Parsons, WH | 1 |
| Williams, BS | 1 |
| Warren, VA | 1 |
| Tschirret-Guth, R | 1 |
| Smith, MM | 1 |
| Priest, BT | 1 |
| McGowan, E | 1 |
| Martin, WJ | 1 |
| Lyons, KA | 1 |
| Li, X | 1 |
| Karanam, BV | 1 |
| Jochnowitz, N | 1 |
| Garcia, ML | 1 |
| Felix, JP | 1 |
| Dean, B | 1 |
| Abbadie, C | 1 |
| Kaczorowski, GJ | 1 |
| Duffy, JL | 1 |
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Chang, A | 1 |
| Chang, Y | 1 |
| Wang, SJ | 1 |
| Espinosa-Ruiz, C | 1 |
| Manuguerra, S | 1 |
| Morghese, M | 1 |
| García-Beltrán, JM | 1 |
| Esteban, MÁ | 1 |
| Giuga, M | 1 |
| Messina, CM | 1 |
| Santulli, A | 1 |
| Aguirre-Martínez, GV | 1 |
| André, C | 1 |
| Gagné, F | 1 |
| Martín-Díaz, LM | 1 |
| Yamamoto, Y | 1 |
| Takahashi, Y | 1 |
| Horino, A | 1 |
| Usui, N | 1 |
| Nishida, T | 1 |
| Imai, K | 1 |
| Kagawa, Y | 1 |
| Inoue, Y | 1 |
| Itoh, K | 1 |
| Taniguchi, R | 1 |
| Matsuo, T | 1 |
| Oguro, A | 1 |
| Vogel, CFA | 1 |
| Yamazaki, T | 1 |
| Ishihara, Y | 1 |
| Dambach, H | 1 |
| Hinkerohe, D | 1 |
| Prochnow, N | 1 |
| Stienen, MN | 1 |
| Moinfar, Z | 1 |
| Haase, CG | 1 |
| Hufnagel, A | 1 |
| Faustmann, PM | 1 |
| Sasaki, E | 1 |
| Iida, A | 1 |
| Oda, S | 1 |
| Tsuneyama, K | 1 |
| Fukami, T | 1 |
| Nakajima, M | 1 |
| Yokoi, T | 1 |
| Stepanović-Petrović, RM | 3 |
| Tomić, MA | 3 |
| Vučković, SM | 3 |
| Poznanović, G | 1 |
| Ugrešić, ND | 3 |
| Prostran, MŠ | 3 |
| Bošković, B | 5 |
| Iwamoto, T | 1 |
| Takasugi, Y | 1 |
| Higashino, H | 1 |
| Ito, H | 1 |
| Koga, Y | 1 |
| Nakao, S | 1 |
| Walker, KM | 1 |
| Urban, L | 1 |
| Medhurst, SJ | 1 |
| Patel, S | 1 |
| Panesar, M | 1 |
| Fox, AJ | 1 |
| McIntyre, P | 1 |
| Vuckovic, S | 2 |
| Tomic, M | 2 |
| Stepanovic-Petrovic, R | 2 |
| Ugresic, N | 2 |
| Prostran, M | 2 |
| Paranos, SLj | 1 |
| Kocev, N | 1 |
| Bianchi, M | 1 |
| Rossoni, G | 1 |
| Sacerdote, P | 1 |
| Panerai, AE | 1 |
| Berti, F | 1 |
| Chapman, V | 1 |
| Dickenson, AH | 1 |
1 trial available for carbamazepine and Inflammation
| Article | Year |
|---|---|
Influence of Inflammation on the Pharmacokinetics of Perampanel.
Topics: Adolescent; Adult; Anticonvulsants; C-Reactive Protein; Carbamazepine; Child; Child, Preschool; Dose | 2018 |
17 other studies available for carbamazepine and Inflammation
| Article | Year |
|---|---|
Imidazopyridines: a novel class of hNav1.7 channel blockers.
Topics: Analgesics; Animals; Inflammation; Molecular Structure; NAV1.7 Voltage-Gated Sodium Channel; Pain; P | 2008 |
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Rutin prevents seizures in kainic acid-treated rats: evidence of glutamate levels, inflammation and neuronal loss modulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport Systems; Animals; Ant | 2022 |
Immunity and inflammatory responses in gilthead sea bream (Sparus aurata L.) exposed to sub-lethal mixture of carbamazepine, cadmium chloride and polybrominated diphenyl ether.
Topics: Animals; Cadmium Chloride; Carbamazepine; Fish Diseases; Halogenated Diphenyl Ethers; Immunity, Cell | 2021 |
The effects of human drugs in Corbicula fluminea. Assessment of neurotoxicity, inflammation, gametogenic activity, and energy status.
Topics: Animals; Biomarkers; Caffeine; Carbamazepine; Corbicula; Energy Metabolism; Germ Cells; Humans; Ibup | 2018 |
Suppressive effects of levetiracetam on neuroinflammation and phagocytic microglia: A comparative study of levetiracetam, valproate and carbamazepine.
Topics: Animals; Anticonvulsants; Carbamazepine; Cells, Cultured; Cytokines; Inflammation; Levetiracetam; Ma | 2019 |
Glia and epilepsy: experimental investigation of antiepileptic drugs in an astroglia/microglia co-culture model of inflammation.
Topics: Amines; Animals; Anticonvulsants; Astrocytes; Blotting, Western; Carbamazepine; Cells, Cultured; Coc | 2014 |
Pathogenetic analyses of carbamazepine-induced liver injury in F344 rats focused on immune- and inflammation-related factors.
Topics: Animals; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Disease Models, Ani | 2016 |
Pharmacological interaction between oxcarbazepine and two COX inhibitors in a rat model of inflammatory hyperalgesia.
Topics: Animals; Carbamazepine; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug Interactions; Hype | 2011 |
Antinociceptive action of carbamazepine on thermal hypersensitive pain at spinal level in a rat model of adjuvant-induced chronic inflammation.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Arthritis, Experimental; Carbamazepine; Chron | 2011 |
The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain.
Topics: Algorithms; Animals; Anticonvulsants; Capsaicin; Carbamazepine; Dose-Response Relationship, Drug; Gu | 2003 |
Peripheral antinociception by carbamazepine in an inflammatory mechanical hyperalgesia model in the rat: a new target for carbamazepine?
Topics: Analgesics; Animals; Caffeine; Carbamazepine; Concanavalin A; Disease Models, Animal; Dose-Response | 2006 |
The involvement of peripheral alpha 2-adrenoceptors in the antihyperalgesic effect of oxcarbazepine in a rat model of inflammatory pain.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Carbamazepine; Clonidine; Disease Models, Animal; Dos | 2007 |
Role of alpha2-adrenoceptors in the local peripheral antinociception by carbamazepine in a rat model of inflammatory mechanical hyperalgesia.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Ani | 2007 |
GABAergic mechanisms are involved in the antihyperalgesic effects of carbamazepine and oxcarbazepine in a rat model of inflammatory hyperalgesia.
Topics: Analgesics, Non-Narcotic; Animals; Anticonvulsants; Bicuculline; Carbamazepine; Concanavalin A; Dise | 2008 |
Carbamazepine exerts anti-inflammatory effects in the rat.
Topics: Animals; Anti-Inflammatory Agents; Carbamazepine; Dinoprostone; Dose-Response Relationship, Drug; Ed | 1995 |
Inflammation reveals inhibition of noxious responses of rat spinal neurones by carbamazepine.
Topics: Analysis of Variance; Animals; Carbamazepine; Carrageenan; Evoked Potentials; Inflammation; Male; Ne | 1997 |