carbamazepine has been researched along with Hypersensitivity in 5 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Antibodies recognizing rat cytochrome P450 (CYP) 3A1 but not the closely related human CYPs 3A4/5 have been identified in the sera of patients with hypersensitivity reactions to phenytoin and carbamazepine." | 3.70 | Non-monooxygenase cytochromes P450 as potential human autoantigens in anticonvulsant hypersensitivity reactions. ( Gaedigk, A; Leeder, JS; Lu, X; Timsit, Y, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Daly, AK | 1 |
| Bellman, B | 1 |
| Schachner, LA | 1 |
| Pravder, L | 1 |
| McFalls, S | 1 |
| Shapiro, B | 1 |
| Leeder, JS | 1 |
| Lu, X | 1 |
| Timsit, Y | 1 |
| Gaedigk, A | 1 |
| Miura, Y | 1 |
| Serizawa, N | 1 |
| Nonoyama, S | 1 |
| Kuroda, N | 1 |
| Katagiri, S | 1 |
1 review available for carbamazepine and Hypersensitivity
| Article | Year |
|---|---|
Using genome-wide association studies to identify genes important in serious adverse drug reactions.
Topics: Aryl Hydrocarbon Hydroxylases; Carbamazepine; Chemical and Drug Induced Liver Injury; Cytochrome P-4 | 2012 |
4 other studies available for carbamazepine and Hypersensitivity
| Article | Year |
|---|---|
Oxcarbazepine: hyponatraemia and skin reactions.
Topics: Anticonvulsants; Carbamazepine; France; Humans; Hypersensitivity; Hyponatremia | 2007 |
Carbamazepine hypersensitivity.
Topics: Adolescent; Anti-Inflammatory Agents; Anticonvulsants; Carbamazepine; Female; Humans; Hypersensitivi | 1995 |
Non-monooxygenase cytochromes P450 as potential human autoantigens in anticonvulsant hypersensitivity reactions.
Topics: Amino Acid Sequence; Animals; Anticonvulsants; Autoantigens; Binding Sites; Carbamazepine; Cloning, | 1998 |
[A case of allergic stomatitis due to Carbamazepine (Tegretol)].
Topics: Carbamazepine; Humans; Hypersensitivity; Stomatitis | 1987 |