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carbamazepine and Hyperhomocysteinemia

carbamazepine has been researched along with Hyperhomocysteinemia in 9 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Hyperhomocysteinemia: Condition in which the plasma levels of homocysteine and related metabolites are elevated (

Research Excerpts

ExcerptRelevanceReference
"Eighty-one patients participated in the study: 51 patients with chronic epilepsy (G1) treated with carbamazepine (CBZ) or valproic acid (VPA), and 30 patients with newly diagnosed epilepsy (G2)."9.16The effect of vitamin B supplementation on homocysteine metabolism and clinical state of patients with chronic epilepsy treated with carbamazepine and valproic acid. ( Bochyńska, A; Graban, A; Gugała-Iwaniuk, M; Lechowicz, W; Lipczyńska-Łojkowska, W; Lipska, B; Restel, M; Ryglewicz, D, 2012)
"Eighty-one patients participated in the study: 51 patients with chronic epilepsy (G1) treated with carbamazepine (CBZ) or valproic acid (VPA), and 30 patients with newly diagnosed epilepsy (G2)."5.16The effect of vitamin B supplementation on homocysteine metabolism and clinical state of patients with chronic epilepsy treated with carbamazepine and valproic acid. ( Bochyńska, A; Graban, A; Gugała-Iwaniuk, M; Lechowicz, W; Lipczyńska-Łojkowska, W; Lipska, B; Restel, M; Ryglewicz, D, 2012)
"In this cross-sectional observational study we enrolled consecutive children aged 2-12 years with epilepsy who had received phenytoin or carbamazepine monotherapy for >6 months."3.85Hyperhomocysteinaemia in children receiving phenytoin and carbamazepine monotherapy: a cross-sectional observational study. ( Attri, SV; Chandrasekaran, S; Patil, S; Sahu, JK; Sankhyan, N; Singhi, P; Suthar, R; Tageja, M, 2017)
" Hyperhomocysteinemia was defined as fasting total Hcy above 12 micromol/L and/or post-methionine load concentrations above 38 micromol/L."3.74Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins. ( Apeland, T; Frøyland, ES; Kristensen, O; Mansoor, MA; Strandjord, RE, 2008)
" A total of 25 children with idiopathic epilepsy (8 valproate, 11 carbamazepine, and 6 oxcarbazepine) and 10 healthy children were included in the study."3.74Homocysteine levels in epileptic children receiving antiepileptic drugs. ( Kurul, S; Unalp, A; Yiş, U, 2007)
"Our data indicate that not only fasting but also 6h-PML tHcy levels should be determined in order to identify hyperhomocysteinemia among patients on AEDs."3.70Homocysteine concentrations and methionine loading in patients on antiepileptic drugs. ( Apeland, T; Kristensen, O; Mansoor, MA; Strandjord, RE, 2000)
"Valproic acid treatment, although also associated with hyperhomocysteinaemia, only shows a lowering effect on vitamin B6 levels, which seems to be independent of the MTHFR genotype."1.31Anti-epileptic drug treatment in children: hyperhomocysteinaemia, B-vitamins and the 677C-->T mutation of the methylenetetrahydrofolate reductase gene. ( Artuch, R; Cardo, E; Colomé, C; Farré, C; Monrós, E; Pineda, M; Valls, C; Vilaseca, MA, 2000)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (55.56)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pulido Fontes, L1
Pulido Fontes, M1
Quesada Jiménez, P1
Muruzabal Pérez, J1
Mendioroz Iriarte, M1
Chandrasekaran, S1
Patil, S1
Suthar, R1
Attri, SV1
Sahu, JK1
Sankhyan, N1
Tageja, M1
Singhi, P1
Apeland, T2
Frøyland, ES1
Kristensen, O2
Strandjord, RE2
Mansoor, MA2
Belcastro, V1
Striano, P1
Gorgone, G1
Costa, C1
Ciampa, C1
Caccamo, D1
Pisani, LR1
Oteri, G1
Marciani, MG1
Aguglia, U1
Striano, S1
Ientile, R1
Calabresi, P1
Pisani, F1
Bochyńska, A1
Lipczyńska-Łojkowska, W1
Gugała-Iwaniuk, M1
Lechowicz, W1
Restel, M1
Graban, A1
Lipska, B1
Ryglewicz, D1
Kurul, S1
Unalp, A1
Yiş, U1
Vurucu, S1
Demirkaya, E1
Kul, M1
Unay, B1
Gul, D1
Akin, R1
Gokçay, E1
Vilaseca, MA1
Monrós, E1
Artuch, R1
Colomé, C1
Farré, C1
Valls, C1
Cardo, E1
Pineda, M1

Trials

1 trial available for carbamazepine and Hyperhomocysteinemia

ArticleYear
The effect of vitamin B supplementation on homocysteine metabolism and clinical state of patients with chronic epilepsy treated with carbamazepine and valproic acid.
    Seizure, 2012, Volume: 21, Issue:4

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Dietary Supplements; Epilepsy; Female; Foli

2012

Other Studies

8 other studies available for carbamazepine and Hyperhomocysteinemia

ArticleYear
Comparative case-control study of homocysteine, vitamin B
    Neurologia (Barcelona, Spain), 2017, Volume: 32, Issue:7

    Topics: Adult; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Case-Control Studies; Epilepsy; Fema

2017
Hyperhomocysteinaemia in children receiving phenytoin and carbamazepine monotherapy: a cross-sectional observational study.
    Archives of disease in childhood, 2017, Volume: 102, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Child, Preschool; Cross-Sectional Studi

2017
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins.
    Epilepsy research, 2008, Volume: 82, Issue:1

    Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation;

2008
Hyperhomocysteinemia in epileptic patients on new antiepileptic drugs.
    Epilepsia, 2010, Volume: 51, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Enzyme Induction; Epilepsy; Female; Folic Acid; F

2010
Homocysteine levels in epileptic children receiving antiepileptic drugs.
    Journal of child neurology, 2007, Volume: 22, Issue:12

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Folic Acid; Homocysteine; Human

2007
Evaluation of the relationship between C677T variants of methylenetetrahydrofolate reductase gene and hyperhomocysteinemia in children receiving antiepileptic drug therapy.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Apr-01, Volume: 32, Issue:3

    Topics: Adolescent; Analysis of Variance; Anticonvulsants; Carbamazepine; Child; Chromatography, High Pressu

2008
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
    Acta neurologica Scandinavica, 2000, Volume: 101, Issue:4

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; E

2000
Anti-epileptic drug treatment in children: hyperhomocysteinaemia, B-vitamins and the 677C-->T mutation of the methylenetetrahydrofolate reductase gene.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2000, Volume: 4, Issue:6

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Folic Acid; Genotype; Homocyste

2000