carbamazepine has been researched along with HIV Coinfection in 20 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The associations between abacavir hypersensitivity and HLA-B*57:01 and carbamazepine-induced Stevens-Johnson syndrome and HLA-B*15:02 have been implemented in clinical practice." | 4.91 | New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity. ( Ostrov, DA; Park, BK; Pirmohamed, M, 2015) |
| "Physicians may prescribe carbamazepine for HIV-infected patients to treat seizures or postherpetic neuralgia, which are complications of opportunistic infections such as herpes zoster or toxoplasmosis." | 3.70 | Carbamazepine--indinavir interaction causes antiretroviral therapy failure. ( Brinkman, K; Burger, DM; Hekster, YA; Hugen, PW; Koopmans, PP; Schuurman, R; ter Hofstede, HJ, 2000) |
| "Delavirdine is a non-nucleoside reverse transcriptase inhibitor used in combination regimens for the treatment of HIV-1 infection." | 2.71 | Population pharmacokinetics of delavirdine and N-delavirdine in HIV-infected individuals. ( Dicenzo, R; DiFrancesco, R; Fischl, M; Forrest, A; Friedland, G; Morse, GD; Para, M; Pollard, R; Shelton, M; Smith, PF, 2005) |
| "This neuropathy causes pain, paresthesias and burning sensations and/or numbness in the feet, which sometimes occurs in the hands as well." | 2.41 | [Sensory neuropathy in HIV infection: pathogenesis and therapy]. ( Portegies, P; Rosenberg, NR, 2001) |
| " Hence, potential drug-drug interactions (DDIs) may occur between these 2 drugs and antiretrovirals." | 1.56 | Drug-Drug Interactions Between Antiretrovirals and Carbamazepine/Oxcarbazepine: A Real-Life Investigation. ( Atzori, C; Baldelli, S; Cattaneo, D; Cozzi, V; Filice, C; Fusi, M; Gervasoni, C; Micheli, V, 2020) |
| "Seizures were treated with sodium valproate (n = 11), phenobarbital (n = 3), diazepam (n = 2), lamotrigine (n = 1), and carbamazepine (n = 1)." | 1.39 | Prevalence of seizures in children infected with human immunodeficiency virus. ( Eley, B; Petersen, R; Samia, P; Walker, KG; Wilmshurst, JM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 9 (45.00) | 29.6817 |
| 2010's | 7 (35.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cattaneo, D | 1 |
| Baldelli, S | 1 |
| Cozzi, V | 1 |
| Fusi, M | 1 |
| Atzori, C | 1 |
| Micheli, V | 1 |
| Filice, C | 1 |
| Gervasoni, C | 1 |
| Baranyai, D | 1 |
| Muro, E | 1 |
| Gödtel-Armbrust, U | 1 |
| Schirmer, MA | 1 |
| Kisanga, E | 1 |
| Diczfalusy, U | 1 |
| Fillekes, Q | 2 |
| Schuurman, R | 3 |
| Burger, D | 1 |
| Wojnowski, L | 1 |
| Burger, DM | 4 |
| Arends, JE | 1 |
| Jacobs, BS | 1 |
| van Elst-Laurijsen, DH | 1 |
| de Kanter, CT | 1 |
| van Maarseveen, EM | 1 |
| Verwey-van Wissen, CP | 1 |
| Hoepelman, AI | 1 |
| Pirmohamed, M | 1 |
| Ostrov, DA | 1 |
| Park, BK | 1 |
| Muro, EP | 1 |
| Kisanga, ER | 1 |
| L'homme, R | 1 |
| Aitken, SC | 1 |
| Mariki, G | 1 |
| Van der Ven, AJ | 1 |
| Dolmans, W | 1 |
| Walker, AS | 1 |
| Gibb, DM | 1 |
| Samia, P | 1 |
| Petersen, R | 1 |
| Walker, KG | 1 |
| Eley, B | 1 |
| Wilmshurst, JM | 1 |
| Llano, A | 1 |
| Brander, C | 1 |
| Illing, PT | 1 |
| Vivian, JP | 1 |
| Purcell, AW | 1 |
| Rossjohn, J | 1 |
| McCluskey, J | 1 |
| Smith, PF | 1 |
| Dicenzo, R | 1 |
| Forrest, A | 1 |
| Shelton, M | 1 |
| Friedland, G | 1 |
| Para, M | 1 |
| Pollard, R | 1 |
| Fischl, M | 1 |
| DiFrancesco, R | 1 |
| Morse, GD | 1 |
| Droste, JA | 1 |
| Koopmans, PP | 2 |
| Hekster, YA | 2 |
| Goicoechea, M | 1 |
| Best, B | 1 |
| Capparelli, E | 1 |
| Haubrich, R | 1 |
| Smith, KJ | 1 |
| Skelton, HG | 1 |
| Redondo, P | 1 |
| Vázquez-Doval, J | 1 |
| Hugen, PW | 1 |
| Brinkman, K | 1 |
| ter Hofstede, HJ | 1 |
| Goyal, NN | 1 |
| Dhurat, RS | 1 |
| Jerajani, HR | 1 |
| Burman, W | 1 |
| Orr, L | 1 |
| Mateu-de Antonio, J | 1 |
| Grau, S | 1 |
| Gimeno-Bayón, JL | 1 |
| Carmona, A | 1 |
| Portegies, P | 1 |
| Rosenberg, NR | 1 |
| Brooks, J | 1 |
| Daily, J | 1 |
| Schwamm, L | 1 |
| Udawat, H | 1 |
| Khandelwal, V | 1 |
| D'Souza, P | 1 |
| Goyal, RK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Single Dose Carbamazepine on the Pharmacokinetics of Single Dose Nevirapine (Viramune, NVP) and Development of NVP Resistance, PMTCT Program of Moshi, Tanzania (VITA1)[NCT00294892] | Phase 2 | 144 participants (Actual) | Interventional | 2006-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for carbamazepine and HIV Coinfection
| Article | Year |
|---|---|
New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity.
Topics: Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity; Gene Expression Regulation; Genetic Hetero | 2015 |
Human leukocyte antigen-associated drug hypersensitivity.
Topics: Animals; Anti-HIV Agents; Anticonvulsants; Antigen Presentation; Autoantigens; Carbamazepine; Dideox | 2013 |
[Sensory neuropathy in HIV infection: pathogenesis and therapy].
Topics: Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Carba | 2001 |
2 trials available for carbamazepine and HIV Coinfection
| Article | Year |
|---|---|
Intrapartum single-dose carbamazepine reduces nevirapine levels faster and may decrease resistance after a single dose of nevirapine for perinatal HIV prevention.
Topics: Adolescent; Adult; Carbamazepine; CD4 Lymphocyte Count; Chi-Square Distribution; Drug Interactions; | 2012 |
Population pharmacokinetics of delavirdine and N-delavirdine in HIV-infected individuals.
Topics: Adolescent; Adult; Anti-HIV Agents; Body Weight; Carbamazepine; Delavirdine; Double-Blind Method; Dr | 2005 |
15 other studies available for carbamazepine and HIV Coinfection
| Article | Year |
|---|---|
Drug-Drug Interactions Between Antiretrovirals and Carbamazepine/Oxcarbazepine: A Real-Life Investigation.
Topics: Adult; Anti-Retroviral Agents; Anticonvulsants; Atazanavir Sulfate; Carbamazepine; Darunavir; Drug I | 2020 |
Reduction of nevirapine-driven HIV mutations by carbamazepine is modulated by CYP3A activity.
Topics: Anti-HIV Agents; Carbamazepine; Chemoprevention; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Indu | 2014 |
Managing drug-drug interactions in an HIV-infected patient receiving antiretrovirals, anti-HCV therapy and carbamazepine: a 'tour de force' for clinical pharmacologists.
Topics: Anticonvulsants; Antiviral Agents; Atazanavir Sulfate; Carbamazepine; Cytochrome P-450 CYP3A; Drug D | 2014 |
Prevalence of seizures in children infected with human immunodeficiency virus.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; HIV Infections; Humans; Male; Pheno | 2013 |
Mechanisms involved in the Abacavir-mediated hypersensitivity syndrome.
Topics: Alleles; Anti-HIV Agents; Autoimmunity; Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity; HI | 2012 |
TDM: therapeutic drug measuring or therapeutic drug monitoring?
Topics: Anti-Retroviral Agents; Carbamazepine; Drug Interactions; Drug Monitoring; Drug Resistance, Viral; H | 2005 |
Concurrent use of efavirenz and oxcarbazepine may not affect efavirenz plasma concentrations.
Topics: Adult; Alkynes; Anti-HIV Agents; Anticonvulsants; Benzoxazines; Bipolar Disorder; Carbamazepine; Cyc | 2006 |
Accidental success with carbamazepine for psoriatic erythroderma.
Topics: Adult; Carbamazepine; Dermatitis, Exfoliative; HIV Infections; Humans; Male; Psoriasis | 1996 |
Carbamazepine and psoriasis.
Topics: Adjuvants, Immunologic; Anti-HIV Agents; Carbamazepine; Dermatitis, Exfoliative; Dermatologic Agents | 1998 |
Carbamazepine--indinavir interaction causes antiretroviral therapy failure.
Topics: Anti-HIV Agents; Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Drug Interactio | 2000 |
Carbamazepine in Reiter's syndrome.
Topics: Adult; Arthritis, Reactive; Carbamazepine; Dermatologic Agents; HIV Infections; Humans; Male | 2000 |
Carbamazepine toxicity after starting combination antiretroviral therapy including ritonavir and efavirenz.
Topics: Alkynes; Anti-HIV Agents; Anticonvulsants; Antiretroviral Therapy, Highly Active; Benzoxazines; Carb | 2000 |
Ritonavir-induced carbamazepine toxicity.
Topics: Adult; Anticonvulsants; Ataxia; Carbamazepine; Drug Interactions; HIV Infections; HIV Protease Inhib | 2001 |
Protease inhibitors and anticonvulsants.
Topics: Anti-HIV Agents; Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-45 | 1997 |
Toxic epidermal necrolysis secondary to carbamazepine in a patient with human immunodeficiency virus infection.
Topics: Adrenal Cortex Hormones; Adult; Analgesics, Non-Narcotic; Carbamazepine; Follow-Up Studies; HIV Infe | 2001 |