carbamazepine has been researched along with Glioma in 22 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "More than two-thirds of patients with WHO grade 2 glioma related epilepsy treated with levetiracetam first line achieve seizure freedom within 2 years and it is a reasonable first-choice agent." | 8.31 | Levetiracetam as a first-line antiseizure medication in WHO grade 2 glioma: Time to seizure freedom and rates of treatment failure. ( Chumas, P; Fairclough, S; Goodden, J; Maguire, M; Mathew, R, 2023) |
| "We conducted a prospective, observational study to verify the efficacy, tolerability and impact on quality of life, mood and global neurocognitive performances of oxcarbazepine monotherapy in patients with brain tumor-related epilepsy (BTRE)." | 7.78 | Oxcarbazepine monotherapy in patients with brain tumor-related epilepsy: open-label pilot study for assessing the efficacy, tolerability and impact on quality of life. ( Dinapoli, L; Fabi, A; Maschio, M; Muti, P; Pace, A; Sperati, F; Vidiri, A, 2012) |
| " We analyzed the data related to 150 patients harboring supratentorial brain gliomas with the aim to assess the efficacy of oxcarbazepine in preventing the occurrence or the recurrence of early postoperative seizures and its tolerability when it is rapidly titrated." | 7.74 | Prevention of early postoperative seizures in patients with primary brain tumors: preliminary experience with oxcarbazepine. ( Bomprezzi, C; Formica, F; Iacoangeli, M; Mauro, AM; Morresi, S; Provinciali, L; Scerrati, M, 2007) |
| "Effects of the antiepileptic drug carbamazepine on nerve action potential and transmitter release in mouse neuroblastoma-glioma hybrid cells (NG108-15) and the frog neuromuscular junction were studied." | 7.70 | Effects of carbamazepine on nerve activity and transmitter release in neuroblastoma-glioma hybrid cells and the frog neuromuscular junction. ( Enomoto, K; Maeno, T; Matsumoto, Y; Moritake, K, 1998) |
| "The population pharmacokinetic model reported here was developed using data from 2 phase 2 trials of irinotecan for treatment of malignant glioma to quantify the impact of concomitant therapy with enzyme-inducing antiepileptic drugs (EIAEDs) on irinotecan pharmacokinetics." | 5.20 | Quantification of the impact of enzyme-inducing antiepileptic drugs on irinotecan pharmacokinetics and SN-38 exposure. ( Ames, MM; Berg, AK; Buckner, JC; Galanis, E; Jaeckle, KA; Reid, JM, 2015) |
| "More than two-thirds of patients with WHO grade 2 glioma related epilepsy treated with levetiracetam first line achieve seizure freedom within 2 years and it is a reasonable first-choice agent." | 4.31 | Levetiracetam as a first-line antiseizure medication in WHO grade 2 glioma: Time to seizure freedom and rates of treatment failure. ( Chumas, P; Fairclough, S; Goodden, J; Maguire, M; Mathew, R, 2023) |
| " The present study investigated four common antiepileptic drugs, perampanel, carbamazepine (CBZ), sodium valproate (VPA) and levetiracetam (LEV), which are expected to have antitumor effects, and determined the most beneficial drug for the treatment of malignant glioma by comparing antitumor effects such as inhibition of cell proliferation and suppression of migration and invasion (using Transwell assays)." | 4.12 | Anti‑tumor effects of anti‑epileptic drugs in malignant glioma cells. ( Hanashima, Y; Hara, H; Katayama, Y; Ozawa, Y; Sano, E; Sumi, K; Tatsuoka, J; Yagi, C; Yamamuro, S; Yoshimura, S; Yoshino, A, 2022) |
| "We conducted a prospective, observational study to verify the efficacy, tolerability and impact on quality of life, mood and global neurocognitive performances of oxcarbazepine monotherapy in patients with brain tumor-related epilepsy (BTRE)." | 3.78 | Oxcarbazepine monotherapy in patients with brain tumor-related epilepsy: open-label pilot study for assessing the efficacy, tolerability and impact on quality of life. ( Dinapoli, L; Fabi, A; Maschio, M; Muti, P; Pace, A; Sperati, F; Vidiri, A, 2012) |
| " We analyzed the data related to 150 patients harboring supratentorial brain gliomas with the aim to assess the efficacy of oxcarbazepine in preventing the occurrence or the recurrence of early postoperative seizures and its tolerability when it is rapidly titrated." | 3.74 | Prevention of early postoperative seizures in patients with primary brain tumors: preliminary experience with oxcarbazepine. ( Bomprezzi, C; Formica, F; Iacoangeli, M; Mauro, AM; Morresi, S; Provinciali, L; Scerrati, M, 2007) |
| "Effects of the antiepileptic drug carbamazepine on nerve action potential and transmitter release in mouse neuroblastoma-glioma hybrid cells (NG108-15) and the frog neuromuscular junction were studied." | 3.70 | Effects of carbamazepine on nerve activity and transmitter release in neuroblastoma-glioma hybrid cells and the frog neuromuscular junction. ( Enomoto, K; Maeno, T; Matsumoto, Y; Moritake, K, 1998) |
| " In C6 glioma cells, endogenous ADP ribosylation was markedly increased by lithium chloride (+83%, P < 0." | 3.69 | Mood stabilizers have differential effects on endogenous ADP ribosylation in C6 glioma cells. ( Woods, CM; Young, LT, 1996) |
| "Levetiracetam was very well tolerated." | 1.42 | Epilepsy in patients with gliomas: incidence and control of seizures. ( Hasegawa, Y; Iuchi, T; Kawasaki, K; Sakaida, T, 2015) |
| "Although seizures in brain tumor patients are common, the knowledge on optimal anti-seizure therapy in this patient group is limited." | 1.35 | Efficacy of anti-epileptic drugs in patients with gliomas and seizures. ( Rijsman, RM; Taphoorn, MJ; van Breemen, MS; Vecht, CJ; Walchenbach, R; Zwinkels, H, 2009) |
| "Levetiracetam was more likely to be used in children who received chemotherapy or radiation therapy (8/14, or 57%) than in those who did not receive adjuvant therapies (3/18, or 17%) (P = 0." | 1.35 | The use of antiepileptic drugs in pediatric brain tumor patients. ( Kan, L; Levy, AS; Maytal, J; Shinnar, S; Sogawa, Y, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.09) | 18.7374 |
| 1990's | 9 (40.91) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Yagi, C | 1 |
| Tatsuoka, J | 1 |
| Sano, E | 1 |
| Hanashima, Y | 1 |
| Ozawa, Y | 1 |
| Yoshimura, S | 1 |
| Yamamuro, S | 1 |
| Sumi, K | 1 |
| Hara, H | 1 |
| Katayama, Y | 1 |
| Yoshino, A | 1 |
| Fairclough, S | 1 |
| Goodden, J | 1 |
| Chumas, P | 1 |
| Mathew, R | 1 |
| Maguire, M | 1 |
| Iuchi, T | 1 |
| Hasegawa, Y | 1 |
| Kawasaki, K | 1 |
| Sakaida, T | 1 |
| Berg, AK | 1 |
| Buckner, JC | 1 |
| Galanis, E | 1 |
| Jaeckle, KA | 1 |
| Ames, MM | 1 |
| Reid, JM | 1 |
| van Breemen, MS | 1 |
| Rijsman, RM | 1 |
| Taphoorn, MJ | 1 |
| Walchenbach, R | 1 |
| Zwinkels, H | 1 |
| Vecht, CJ | 1 |
| Sogawa, Y | 1 |
| Kan, L | 1 |
| Levy, AS | 1 |
| Maytal, J | 1 |
| Shinnar, S | 1 |
| Maschio, M | 1 |
| Dinapoli, L | 1 |
| Sperati, F | 1 |
| Fabi, A | 1 |
| Pace, A | 1 |
| Vidiri, A | 1 |
| Muti, P | 1 |
| Kuhn, JG | 1 |
| Assencio-Ferreira, VJ | 1 |
| Mussi, ML | 1 |
| Guirado, VM | 1 |
| Veiga, JC | 1 |
| Mauro, AM | 1 |
| Bomprezzi, C | 1 |
| Morresi, S | 1 |
| Provinciali, L | 1 |
| Formica, F | 1 |
| Iacoangeli, M | 1 |
| Scerrati, M | 1 |
| Zakir Hossain, SM | 1 |
| Shinohara, H | 1 |
| Kitano, H | 1 |
| Schnabel, R | 1 |
| Rambeck, B | 1 |
| May, TW | 1 |
| Jürgens, U | 1 |
| Lahl, R | 1 |
| Chen, G | 2 |
| Pan, B | 1 |
| Hawver, DB | 1 |
| Wright, CB | 1 |
| Potter, WZ | 2 |
| Manji, HK | 2 |
| Young, LT | 1 |
| Woods, CM | 1 |
| Yamaji, T | 1 |
| Kagaya, A | 1 |
| Uchitomi, Y | 1 |
| Yokata, N | 1 |
| Yamawaki, S | 1 |
| Hsiao, JK | 1 |
| Risby, ED | 1 |
| Masana, MI | 1 |
| Ständer, M | 1 |
| Dichgans, J | 1 |
| Weller, M | 1 |
| Matsumoto, Y | 1 |
| Enomoto, K | 1 |
| Moritake, K | 1 |
| Maeno, T | 1 |
| Arroyo, S | 1 |
| Rumiá, J | 1 |
| Martínez, I | 1 |
| Ribalta, T | 1 |
| Shaw, MD | 1 |
| Rektor, I | 1 |
| Bednarík, J | 1 |
| Svejdová, M | 1 |
| Tenser, RB | 1 |
| Corbett, JJ | 1 |
1 review available for carbamazepine and Glioma
| Article | Year |
|---|---|
Regulation of signal transduction pathways by mood-stabilizing agents: implications for the delayed onset of therapeutic efficacy.
Topics: Adenylyl Cyclases; Animals; Bipolar Disorder; Carbamazepine; Cell Line; Glioma; GTP-Binding Proteins | 1996 |
3 trials available for carbamazepine and Glioma
| Article | Year |
|---|---|
Quantification of the impact of enzyme-inducing antiepileptic drugs on irinotecan pharmacokinetics and SN-38 exposure.
Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Carb | 2015 |
Influence of anticonvulsants on the metabolism and elimination of irinotecan. A North American Brain Tumor Consortium preliminary report.
Topics: Anticonvulsants; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Carbamazepine; Do | 2002 |
Post-operative epilepsy and the efficacy of anticonvulsant therapy.
Topics: Anticonvulsants; Brain Neoplasms; Carbamazepine; Epilepsies, Partial; Follow-Up Studies; Glioma; Hum | 1990 |
18 other studies available for carbamazepine and Glioma
| Article | Year |
|---|---|
Anti‑tumor effects of anti‑epileptic drugs in malignant glioma cells.
Topics: Anticonvulsants; Cadherins; Carbamazepine; Glioma; Humans; Levetiracetam; Matrix Metalloproteinase 2 | 2022 |
Levetiracetam as a first-line antiseizure medication in WHO grade 2 glioma: Time to seizure freedom and rates of treatment failure.
Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Freedom; Glioma; Humans; Levetiraceta | 2023 |
Epilepsy in patients with gliomas: incidence and control of seizures.
Topics: Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Carbamazepine; Female; Glioma; Humans; Inci | 2015 |
Efficacy of anti-epileptic drugs in patients with gliomas and seizures.
Topics: Adult; Anticonvulsants; Brain Neoplasms; Carbamazepine; Drug Therapy, Combination; Female; Follow-Up | 2009 |
The use of antiepileptic drugs in pediatric brain tumor patients.
Topics: Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Carbamazepine; Child; Drug Interactions; Fo | 2009 |
Oxcarbazepine monotherapy in patients with brain tumor-related epilepsy: open-label pilot study for assessing the efficacy, tolerability and impact on quality of life.
Topics: Adult; Aged; Anticonvulsants; Brain Neoplasms; Carbamazepine; Epilepsy; Female; Glioma; Humans; Male | 2012 |
[Transient lesion in the splenium of the corpus callosum in epileptic child with cerebral low grade glioma].
Topics: Anticonvulsants; Brain Neoplasms; Carbamazepine; Child; Corpus Callosum; Epilepsy, Complex Partial; | 2005 |
Prevention of early postoperative seizures in patients with primary brain tumors: preliminary experience with oxcarbazepine.
Topics: Anticonvulsants; Carbamazepine; Glioma; Humans; Neurosurgical Procedures; Oxcarbazepine; Postoperati | 2007 |
Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.
Topics: 4-Aminopyridine; Animals; Brain Neoplasms; Carbamazepine; Cell Line, Tumor; Enzymes; Flunarizine; Gl | 2008 |
Concentrations of carbamazepine and carbamazepine-10, 11-epoxide in serum, brain tumors and paratumorous cortex: a prospective study of 37 neurosurgically treated epileptic patients.
Topics: Adolescent; Adult; Aged; Biological Availability; Biopsy; Brain Neoplasms; Carbamazepine; Cerebral C | 1994 |
Attenuation of cyclic AMP production by carbamazepine.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylate Cyclase Toxin; Adenylyl | 1996 |
Mood stabilizers have differential effects on endogenous ADP ribosylation in C6 glioma cells.
Topics: Adenosine Diphosphate Ribose; Animals; Carbamazepine; Glioma; Lithium Chloride; Rats; Tumor Cells, C | 1996 |
Effects of carbamazepine and sodium valproate on 5-HT-induced calcium increase in individual C6 rat glioma cells.
Topics: Animals; Calcium; Carbamazepine; Cells, Cultured; Glioma; Rats; Serotonin; Valproic Acid | 1996 |
Anticonvulsant drugs fail to modulate chemotherapy-induced cytotoxicity and growth inhibition of human malignant glioma cells.
Topics: Anticonvulsants; Antineoplastic Agents; Carbamazepine; Cell Division; Cell Survival; Glioma; Humans; | 1998 |
Effects of carbamazepine on nerve activity and transmitter release in neuroblastoma-glioma hybrid cells and the frog neuromuscular junction.
Topics: Action Potentials; Animals; Calcium; Carbamazepine; Glioma; Mice; Neuroblastoma; Neuromuscular Block | 1998 |
[Drug-resistant epilepsy].
Topics: Adult; Anticonvulsants; Brain Neoplasms; Calcinosis; Carbamazepine; Diagnosis, Differential; Drug Re | 1998 |
[Anticonvulsants in the therapy of glioblastomas].
Topics: Adult; Anticonvulsants; Brain Neoplasms; Carbamazepine; Combined Modality Therapy; Drug Therapy, Com | 1986 |
Myokymia and facial contraction in brain stem glioma. An electromyographic study.
Topics: Action Potentials; Adult; Brain Neoplasms; Carbamazepine; Diazepam; Edrophonium; Electromyography; F | 1974 |