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carbamazepine and Encephalopathy, Toxic

carbamazepine has been researched along with Encephalopathy, Toxic in 12 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Research Excerpts

ExcerptRelevanceReference
" In this study we evaluated the efficacy and safety of carbamazepine for prevention of oxaliplatin-associated neuropathy in patients with advanced colorectal cancer."9.12Carbamazepine for prevention of oxaliplatin-related neurotoxicity in patients with advanced colorectal cancer: final results of a randomised, controlled, multicenter phase II study. ( Adelsberger, H; Bredenkamp, R; Eckel, F; Erdmann, J; Kullmann, F; Lersch, C; Mayr, M; Obermeier, F; Quasthoff, S; Schmelz, R; Schmid, RM; Stock, K; von Delius, S; Wagenpfeil, S, 2007)
" In this study we evaluated the efficacy and safety of carbamazepine for prevention of oxaliplatin-associated neuropathy in patients with advanced colorectal cancer."5.12Carbamazepine for prevention of oxaliplatin-related neurotoxicity in patients with advanced colorectal cancer: final results of a randomised, controlled, multicenter phase II study. ( Adelsberger, H; Bredenkamp, R; Eckel, F; Erdmann, J; Kullmann, F; Lersch, C; Mayr, M; Obermeier, F; Quasthoff, S; Schmelz, R; Schmid, RM; Stock, K; von Delius, S; Wagenpfeil, S, 2007)
"A novel class of 19 carbamates was synthesized, and their anticonvulsant activity was comparatively evaluated in the rat maximal electroshock (MES) and subcutaneous metrazol (scMet) seizure tests and pilocarpine-induced status epilepticus (SE) model."3.78Syntheses and evaluation of anticonvulsant activity of novel branched alkyl carbamates. ( Bialer, M; Hen, N; Yagen, B, 2012)
" We investigated and compared the toxic effects of two dibenz[b,f]azepine derivatives with anticonvulsant activity, 10,11-dihydro-10-hydroxyimino-5H-dibenz[b,f]azepine-5-carboxamide (BIA2-024) and (S)-(-)-10-acetoxy-10,11-dihydro-5H-dibenz[b,f] azepine-5-carboxamide (BIA2-093), with the structurally related compounds carbamazepine (CBZ) and oxcarbazepine (OXC), both in current use for the treatment of epilepsy."3.72Neurotoxicity induced by antiepileptic drugs in cultured hippocampal neurons: a comparative study between carbamazepine, oxcarbazepine, and two new putative antiepileptic drugs, BIA 2-024 and BIA 2-093. ( Ambrósio, AF; Araújo, IM; Carvalho, AP; Carvalho, CM; Leal, EC; Malva, JO; Soares-da-Silva, P; Verdasca, MJ, 2004)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (66.67)29.6817
2010's2 (16.67)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Xie, ZF1
Chai, KY1
Piao, HR1
Kwak, KC1
Quan, ZS1
Hen, N1
Bialer, M1
Yagen, B1
Hirsch, A1
Wanounou, M1
Perlman, A1
Hirsh-Raccah, B1
Muszkat, M1
Beghin, M1
Schmitz, M1
Betoulle, S1
Palluel, O1
Baekelandt, S1
Mandiki, SNM1
Gillet, E1
Nott, K1
Porcher, JM1
Robert, C1
Ronkart, S1
Kestemont, P1
Ozhasenekler, A1
Gökhan, S1
Güloğlu, C1
Orak, M1
Ustündağ, M1
Schmelz, R3
Lersch, C3
Eckel, F2
Erdmann, J2
Mayr, M2
Schulte-Frohlinde, E1
Quasthoff, S2
Grosskreutz, J1
Adelsberger, H2
Guilloton, L1
Drouet, A1
Renoult, PA1
Bedubourg, G1
Vial, T1
Felten, D1
Luszczki, JJ2
Czuczwar, SJ2
Araújo, IM1
Ambrósio, AF1
Leal, EC1
Verdasca, MJ1
Malva, JO1
Soares-da-Silva, P1
Carvalho, AP1
Carvalho, CM1
Antkiewicz-Michaluk, L1
von Delius, S1
Wagenpfeil, S1
Stock, K1
Kullmann, F1
Obermeier, F1
Bredenkamp, R1
Schmid, RM1

Trials

1 trial available for carbamazepine and Encephalopathy, Toxic

ArticleYear
Carbamazepine for prevention of oxaliplatin-related neurotoxicity in patients with advanced colorectal cancer: final results of a randomised, controlled, multicenter phase II study.
    Investigational new drugs, 2007, Volume: 25, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents; Carbamazepine; Colorectal Ne

2007

Other Studies

11 other studies available for carbamazepine and Encephalopathy, Toxic

ArticleYear
Synthesis and anticonvulsant activity of 7-alkoxyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolines.
    Bioorganic & medicinal chemistry letters, 2005, Nov-01, Volume: 15, Issue:21

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Mice; Neurotoxicity Syndromes; Quinolines; Seizure

2005
Syntheses and evaluation of anticonvulsant activity of novel branched alkyl carbamates.
    Journal of medicinal chemistry, 2012, Mar-22, Volume: 55, Issue:6

    Topics: Animals; Anticonvulsants; Carbamates; Male; Mice; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawle

2012
The effect of multidrug exposure on neurological manifestations in carbamazepine intoxication: a nested case-control study.
    BMC pharmacology & toxicology, 2020, 06-29, Volume: 21, Issue:1

    Topics: Adult; Anticonvulsants; Antidepressive Agents; Benzodiazepines; Carbamazepine; Case-Control Studies;

2020
Integrated multi-biomarker responses of juvenile rainbow trout (Oncorhynchus mykiss) to an environmentally relevant pharmaceutical mixture.
    Ecotoxicology and environmental safety, 2021, Sep-15, Volume: 221

    Topics: Acetaminophen; Animals; Belgium; Biomarkers; Brain; Carbamazepine; Diclofenac; Irbesartan; Liver; Ly

2021
Benefit of hemodialysis in carbamazepine intoxications with neurological complications.
    European review for medical and pharmacological sciences, 2012, Volume: 16 Suppl 1

    Topics: Adult; Anticonvulsants; Antidotes; Carbamazepine; Charcoal; Drug Overdose; Female; Gastric Lavage; G

2012
Acute oxaliplatin-induced peripheral-nerve hyperexcitability.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Aug-15, Volume: 20, Issue:16

    Topics: Anticonvulsants; Antineoplastic Agents; Carbamazepine; Humans; Neurotoxicity Syndromes; Organoplatin

2002
Prevention of oxaliplatin-induced peripheral sensory neuropathy by carbamazepine in patients with advanced colorectal cancer.
    Clinical colorectal cancer, 2002, Volume: 2, Issue:1

    Topics: Animals; Antineoplastic Agents; Carbamazepine; Colorectal Neoplasms; Humans; In Vitro Techniques; Ne

2002
[Oxcarbazepine-induced encephalopathy].
    Presse medicale (Paris, France : 1983), 2003, Sep-06, Volume: 32, Issue:28

    Topics: Adult; Anticonvulsants; Antimalarials; Carbamazepine; Chloroquine; Confusion; Epilepsy; Female; Huma

2003
Preclinical profile of combinations of some second-generation antiepileptic drugs: an isobolographic analysis.
    Epilepsia, 2004, Volume: 45, Issue:8

    Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Evaluation, Preclinical; Drug

2004
Neurotoxicity induced by antiepileptic drugs in cultured hippocampal neurons: a comparative study between carbamazepine, oxcarbazepine, and two new putative antiepileptic drugs, BIA 2-024 and BIA 2-093.
    Epilepsia, 2004, Volume: 45, Issue:12

    Topics: Animals; Anticonvulsants; Carbamazepine; Cell Survival; Cells, Cultured; Dibenzazepines; Epilepsy; H

2004
1-Methyl-1,2,3,4-tetrahydroisoquinoline enhances the anticonvulsant action of carbamazepine and valproate in the mouse maximal electroshock seizure model.
    Neuropharmacology, 2006, Volume: 50, Issue:2

    Topics: Animals; Anticonvulsants; Carbamazepine; Dopamine Antagonists; Dyskinesia, Drug-Induced; Electroshoc

2006