Page last updated: 2024-10-24

carbamazepine and Dystonia

carbamazepine has been researched along with Dystonia in 48 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)

Research Excerpts

ExcerptRelevanceReference
"We report a patient who developed paroxysmal kinesigenic dystonia shortly after initiation of therapy with methylphenidate for presumed attention deficit-hyperactivity disorder."7.69Paroxysmal kinesigenic dystonia after methylphenidate administration. ( Gay, CT; Ryan, SG, 1994)
"Carbamazepine is an anticonvulsant most effective in treating complex partial and generalized tonic-clonic seizures."7.66Dystonia associated with carbamazepine administration: experience in brain-damaged children. ( Crosley, CJ; Swender, PT, 1979)
"Then topiramate was started, and PTS promptly disappeared."5.42Successful treatment of paroxysmal tonic spasms with topiramate in a patient with neuromyelitis optica. ( Iida, S; Kaneko, S; Kusaka, H; Nakamura, M; Wate, R, 2015)
"Tiagabine may cause various mild extrapyramidal side effects."5.31Transient dystonias in three patients treated with tiagabine. ( Grabowska-Grzyb, A; Wolańczyk, T, 2001)
" Reversible dystonia may occasionally be precipitated by phenytoin or carbamazepine; asterixis by phenytoin, barbiturates or carbamazepine; and, more commonly, tremor by valproate."4.77Adverse neuropsychiatric effects of anticonvulsant drugs. ( Reynolds, EH; Trimble, MR, 1985)
"We report a patient who developed paroxysmal kinesigenic dystonia shortly after initiation of therapy with methylphenidate for presumed attention deficit-hyperactivity disorder."3.69Paroxysmal kinesigenic dystonia after methylphenidate administration. ( Gay, CT; Ryan, SG, 1994)
"Carbamazepine is an anticonvulsant most effective in treating complex partial and generalized tonic-clonic seizures."3.66Dystonia associated with carbamazepine administration: experience in brain-damaged children. ( Crosley, CJ; Swender, PT, 1979)
"Paroxysmal dystonia occurs because of genetic or structural lesion in the basal ganglia or thalamus, and there is paucity of reporting in spinal pathology."1.72Paroxysmal spinal hemidystonia in neuromyelitis optica. ( Gutti, NB; Kalita, J; Pandey, PC, 2022)
"Treatment with carbamazepine failed in two children due to drowsiness and auditory disturbance."1.56Lacosamide for children with paroxysmal kinesigenic dyskinesia. ( Furukawa, G; Ishihara, N; Negishi, Y; Okumura, A; Takeuchi, T, 2020)
"PKC and seizures were readily controlled with small dose of carbamazepine."1.51[An adult female with proline-rich transmembrane protein 2 related paroxysmal disorders manifesting paroxysmal kinesigenic choreoathetosis and epileptic seizures]. ( Awaya, T; Ikeda, A; Inoue, T; Kato, T; Kuzuya, A; Shimotake, A; Taira, T; Takahashi, R; Tanabe, Y, 2019)
"Then topiramate was started, and PTS promptly disappeared."1.42Successful treatment of paroxysmal tonic spasms with topiramate in a patient with neuromyelitis optica. ( Iida, S; Kaneko, S; Kusaka, H; Nakamura, M; Wate, R, 2015)
"Tiagabine may cause various mild extrapyramidal side effects."1.31Transient dystonias in three patients treated with tiagabine. ( Grabowska-Grzyb, A; Wolańczyk, T, 2001)
"The pathophysiologic mechanisms of spasmodic torticollis and other idiopathic torsion dystonias remain unknown."1.27Spasmodic torticollis and other idiopathic torsion dystonias. Medical management. ( Lee, MC, 1984)
"Nocturnal paroxysmal dystonia represents a syndrome of sleep-related motor attacks which comprises two variants, respectively characterised by short and long-lasting seizures."1.27Nocturnal paroxysmal dystonia. ( Cirignotta, F; Lugaresi, E; Montagna, P, 1986)
"We report a case of hypnogenic paroxysmal dystonia (HPD), diagnosed on the basis of typical clinical and neurophysiological criteria."1.27A long-lasting CBZ controlled case of hypnogenic paroxysmal dystonia. ( Manni, R; Piccolo, G; Tartara, A, 1988)
"Carbamazepine treatment was effective in all patients."1.26Hypnogenic paroxysmal dystonia: epileptic seizure or a new syndrome? ( Cirignotta, F; Lugaresi, E, 1981)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199014 (29.17)18.7374
1990's12 (25.00)18.2507
2000's2 (4.17)29.6817
2010's17 (35.42)24.3611
2020's3 (6.25)2.80

Authors

AuthorsStudies
Gutti, NB1
Kalita, J1
Pandey, PC1
Dekker, MCJ1
Chengo, R1
Kumburu, HH1
Kamsteeg, EJ1
Hamel, BC1
Furukawa, G1
Negishi, Y1
Takeuchi, T1
Ishihara, N1
Okumura, A1
Dayasiri, K1
Weerapperuma, N1
Wright, J1
Anand, G1
Naheed, D1
Mehta, S1
Goyal, MK1
Lal, V1
Tan, GH1
Liu, YY1
Wang, L1
Li, K1
Zhang, ZQ1
Li, HF2
Yang, ZF1
Li, Y1
Li, D1
Wu, MY1
Yu, CL1
Long, JJ1
Chen, RC1
Li, LX1
Yin, LP1
Liu, JW1
Cheng, XW1
Shen, Q1
Shu, YS1
Sakimura, K1
Liao, LJ1
Wu, ZY2
Xiong, ZQ2
Zhu, XM1
Gong, YH1
Lu, S1
Cheng, SC1
Yao, BZ1
Paucar, M1
Malmgren, H1
Svenningsson, P1
Kaushik, JS1
Bala, K1
Dubey, R1
Tanabe, Y1
Taira, T1
Shimotake, A1
Inoue, T1
Awaya, T1
Kato, T1
Kuzuya, A1
Ikeda, A1
Takahashi, R1
Chen, WJ1
Ni, W1
Wang, KY1
Liu, GL1
Wang, N1
Xu, J1
Junewar, V1
Sahu, R1
Shukla, R1
Xu, Y1
Liu, XZ1
Gao, XG1
Rizek, P1
Barrett, E1
Jog, M1
Iida, S1
Nakamura, M1
Wate, R1
Kaneko, S1
Kusaka, H1
Gu, C1
Li, J1
Zhu, L1
Lu, Z1
Huang, H1
AlAzwary, NH1
Muayqil, T1
Siddiqi, ZA1
Ahmed, SN1
Odueyungbo, MA1
Sheehan, MP1
Haggstrom, AN1
Della Marca, G1
Frisullo, G1
Vollono, C1
Dittoni, S1
Losurdo, A1
Testani, E1
Colicchio, S1
Gnoni, V1
Rizzo, D1
Riccardi, R1
Batocchi, AP1
Schmidt, FR1
Costa, FH1
Silva, FM1
Maultasch, H1
Rosso, AL1
Nicaretta, DH1
Mattos, JP1
Novis, SA1
Alves-Leon, SV1
Yang, Y1
Su, Y1
Guo, Y1
Ding, Y1
Xu, S1
Jiang, Y1
Wang, S1
Ding, M1
Lee, MC1
Bradbury, AJ1
Bentick, B1
Todd, PJ1
Lugaresi, E2
Cirignotta, F2
Martinón, JM1
Docampo, G1
Martinón, F1
Viso, JA1
Peña, J1
Eriksson, K1
Hirvonen, K1
Koivikko, M1
Lee, JW1
Soman, P1
Jain, S1
Rajsekhar, V1
Vineeta, S1
Sharma, BK1
Gay, CT1
Ryan, SG1
Previdi, P1
Buzzi, P1
Sghirlanzoni, A1
Pareyson, D1
Rodríguez Moreno, E1
Acilona, V1
Boza, F1
Ortega, JE1
Carballo, M1
Palomino, A1
Arenas, C1
Fiedler, A1
Marienhagen, J1
Aderbauer, J1
Bock, E1
Segerer, H1
Eilles, C1
Wolańczyk, T1
Grabowska-Grzyb, A1
Jacome, D1
Crosley, CJ1
Swender, PT1
Fredow, G1
Löscher, W1
Nygaard, TG1
Marsden, CD1
Fahn, S1
Maccario, M1
Lustman, LI1
Silvestri, R1
De Domenico, P1
Casella, C1
Mento, G1
Di Perri, R1
Reynolds, EH1
Trimble, MR1
Montagna, P1
Critchley, EM1
Phillips, M1
Tartara, A1
Manni, R1
Piccolo, G1
Stoudemire, A1
Ninan, PT1
Wooten, V1
Arnstein, E1
Lee, BI1
Lesser, RP1
Pippenger, CE1
Morris, HH1
Lüders, H1
Dinner, DS1
Corrie, WS1
Murphy, WF1
Godbout, R1
Montplaisir, J1
Rouleau, I1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prognosis of Paroxysmal Kinesigenic Choreoathetosis in Korea: a Prospective, Observational Study[NCT04023656]100 participants (Anticipated)Observational [Patient Registry]2016-11-11Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for carbamazepine and Dystonia

ArticleYear
Adverse neuropsychiatric effects of anticonvulsant drugs.
    Drugs, 1985, Volume: 29, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biogenic Amines; Carba

1985

Other Studies

47 other studies available for carbamazepine and Dystonia

ArticleYear
Paroxysmal spinal hemidystonia in neuromyelitis optica.
    Internal medicine journal, 2022, Volume: 52, Issue:8

    Topics: Adult; Autoantibodies; Carbamazepine; Dystonia; Female; Humans; Magnetic Resonance Imaging; Neuromye

2022
Paroxysmal Kinesigenic Dyskinesia: First Molecularly Confirmed Case from Africa.
    Tremor and other hyperkinetic movements (New York, N.Y.), 2019, Volume: 10

    Topics: Anticonvulsants; Carbamazepine; Child; Dystonia; Humans; Male; Membrane Proteins; Nerve Tissue Prote

2019
Lacosamide for children with paroxysmal kinesigenic dyskinesia.
    Brain & development, 2020, Volume: 42, Issue:8

    Topics: Adolescent; Carbamazepine; Child; Dystonia; Female; Humans; Lacosamide; Male; Membrane Proteins; Mut

2020
Paroxysmal kinesigenic dyskinesia: a diagnostic challenge.
    BMJ case reports, 2021, Feb-05, Volume: 14, Issue:2

    Topics: Anticonvulsants; Carbamazepine; Child; Diagnosis, Differential; Dystonia; Female; Humans

2021
Carbamazepine responsive generalized dystonia in Fahr's disease.
    Parkinsonism & related disorders, 2017, Volume: 40

    Topics: Anticonvulsants; Basal Ganglia Diseases; Calcinosis; Carbamazepine; Dystonia; Female; Humans; Middle

2017
PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum.
    Cell research, 2018, Volume: 28, Issue:1

    Topics: Animals; Carbamazepine; Cerebellum; Dystonia; Membrane Proteins; Mice; Mice, 129 Strain; Mice, Inbre

2018
[Clinical manifestations and genetic diagnosis of paroxysmal kinesigenic dyskinesia].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2017, Volume: 19, Issue:11

    Topics: Carbamazepine; Child; Chromosome Deletion; Chromosomes, Human, Pair 16; Dystonia; Electroencephalogr

2017
Paroxysmal Kinesigenic Dyskinesia.
    Tremor and other hyperkinetic movements (New York, N.Y.), 2017, Volume: 7

    Topics: Adult; Anticonvulsants; Carbamazepine; Diagnosis, Differential; Diagnostic Errors; Dystonia; Humans;

2017
Paroxysmal Kinesigenic Dyskinesia.
    Indian pediatrics, 2018, 01-15, Volume: 55, Issue:1

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Dystonia; Humans; Male; Membrane Proteins; Mutation; Ner

2018
[An adult female with proline-rich transmembrane protein 2 related paroxysmal disorders manifesting paroxysmal kinesigenic choreoathetosis and epileptic seizures].
    Rinsho shinkeigaku = Clinical neurology, 2019, Mar-28, Volume: 59, Issue:3

    Topics: Carbamazepine; Dystonia; Electroencephalography; Female; Humans; Membrane Proteins; Mutation; Nerve

2019
PRRT2 mutation correlated with phenotype of paroxysmal kinesigenic dyskinesia and drug response.
    Neurology, 2013, Apr-16, Volume: 80, Issue:16

    Topics: Age of Onset; Anticonvulsants; Athetosis; Carbamazepine; Child; China; Disease Progression; Dyskines

2013
Paroxysmal kinesigenic dyskinesia: a frequently misdiagnosed movement disorder.
    BMJ case reports, 2014, Feb-25, Volume: 2014

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Chorea; Diagnostic Errors; Dystonia; Humans; Male; Somat

2014
[Paroxysmal kinesigenic dyskinesia: 2 case reports].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2014, Aug-18, Volume: 46, Issue:4

    Topics: Carbamazepine; Dystonia; Humans; Male

2014
A case of isolated sudden onset Dysphagia.
    Dysphagia, 2015, Volume: 30, Issue:2

    Topics: Aged; Anticonvulsants; Carbamazepine; Deglutition; Deglutition Disorders; Dystonia; Endoscopy, Diges

2015
Successful treatment of paroxysmal tonic spasms with topiramate in a patient with neuromyelitis optica.
    Multiple sclerosis and related disorders, 2015, Volume: 4, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Drug Eruptions; Dystonia; Female; Fructose; Humans; Middle Aged; Neu

2015
Analysis of catechol-O-methyltransferase gene mutation and identification of new pathogenic gene for paroxysmal kinesigenic dyskinesia.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2016, Volume: 37, Issue:3

    Topics: Adolescent; Age of Onset; Anticonvulsants; Carbamazepine; Catechol O-Methyltransferase; Cell Cycle P

2016
Oculogyric crisis masquerading as ventriculoperitoneal shunt dysfunction.
    Journal of neurosurgery, 2008, Volume: 109, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Diagnosis, Differential; Dystonia; Epilepsy; Female; Humans; Hydroce

2008
HLA-B*1502 allele associated with carbamazepine-induced epidermal necrolysis.
    Archives of dermatology, 2010, Volume: 146, Issue:12

    Topics: Adolescent; Alleles; Analgesics, Non-Narcotic; Carbamazepine; Dystonia; HLA-B Antigens; HLA-B15 Anti

2010
Oculogyric crisis in a midbrain lesion.
    Archives of neurology, 2011, Volume: 68, Issue:3

    Topics: Anti-Inflammatory Agents; Anticonvulsants; Biopsy; Carbamazepine; Cerebral Arteries; Diagnosis, Diff

2011
Paroxysmal dystonia and neuromyelitis optica.
    Arquivos de neuro-psiquiatria, 2012, Volume: 70, Issue:4

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Dystonia; Female; Humans; Middle Aged; Neuromyelitis Op

2012
Oxcarbazepine versus carbamazepine in the treatment of paroxysmal kinesigenic dyskinesia.
    The International journal of neuroscience, 2012, Volume: 122, Issue:12

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Chorea; Dystonia; Electroencephalography; Female;

2012
Spasmodic torticollis and other idiopathic torsion dystonias. Medical management.
    Postgraduate medicine, 1984, May-15, Volume: 75, Issue:7

    Topics: Adrenergic Agents; Amantadine; Antipsychotic Agents; Apomorphine; Benzodiazepines; Carbamazepine; Dy

1984
Dystonia associated with carbamazepine toxicity.
    Postgraduate medical journal, 1982, Volume: 58, Issue:682

    Topics: Carbamazepine; Child; Dystonia; Female; Humans; Male

1982
Hypnogenic paroxysmal dystonia: epileptic seizure or a new syndrome?
    Sleep, 1981, Volume: 4, Issue:2

    Topics: Adult; Aged; Carbamazepine; Child; Diagnosis, Differential; Dystonia; Electroencephalography; Epilep

1981
[Dystonia and carbamazepine (author's transl)].
    Anales espanoles de pediatria, 1980, Volume: 13, Issue:9

    Topics: Carbamazepine; Child; Child, Preschool; Dystonia; Epilepsy; Female; Humans; Male

1980
[Nocturnal paroxysmal dystonia--epilepsy or sleep disorder?].
    Duodecim; laaketieteellinen aikakauskirja, 1994, Volume: 110, Issue:2

    Topics: Anticonvulsants; Carbamazepine; Child; Circadian Rhythm; Diagnosis, Differential; Dystonia; Electroe

1994
Persistent dystonia associated with carbamazepine therapy: a case report.
    The New Zealand medical journal, 1994, Sep-14, Volume: 107, Issue:985

    Topics: Adult; Carbamazepine; Dystonia; Epilepsy, Complex Partial; Female; Humans

1994
Dystonia--a rare manifestation of carbamazepine toxicity.
    Postgraduate medical journal, 1994, Volume: 70, Issue:819

    Topics: Adolescent; Carbamazepine; Dystonia; Female; Humans; Nystagmus, Pathologic

1994
Paroxysmal kinesigenic dystonia after methylphenidate administration.
    Journal of child neurology, 1994, Volume: 9, Issue:1

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Carbamazepine; Dystonia; Humans; Male; Me

1994
Carbamazepine for paroxysmal dystonia due to spinal cord lesions.
    Italian journal of neurological sciences, 1993, Volume: 14, Issue:4

    Topics: Carbamazepine; Chronic Disease; Dystonia; Humans; Multiple Sclerosis; Spinal Cord Injuries

1993
Carbamazepine for paroxysmal dystonia due to spinal cord lesions.
    Italian journal of neurological sciences, 1993, Volume: 14, Issue:2

    Topics: Carbamazepine; Dystonia; Female; Humans; Middle Aged; Spinal Cord Diseases

1993
[Concurrence of short and long lasting episodes of nocturnal paroxysmal dystonia in an epileptic patient].
    Neurologia (Barcelona, Spain), 1997, Volume: 12, Issue:3

    Topics: Adult; Anticonvulsants; Carbamazepine; Dystonia; Electroencephalography; Epilepsy, Complex Partial;

1997
Follow-up findings in regional cerebral blood flow (r-CBF)-SPECT in a case of idiopathic childhood hemidystonia. Functional neuroimaging and pathophysiological implications.
    Nuklearmedizin. Nuclear medicine, 1999, Volume: 38, Issue:2

    Topics: Anticonvulsants; Brain; Carbamazepine; Cerebrovascular Circulation; Child; Dystonia; Female; Follow-

1999
Transient dystonias in three patients treated with tiagabine.
    Epilepsia, 2001, Volume: 42, Issue:7

    Topics: Acute Disease; Adult; Anticonvulsants; Basal Ganglia Diseases; Carbamazepine; Child; Dose-Response R

2001
Carbamazepine-induced dystonia.
    JAMA, 1979, May-25, Volume: 241, Issue:21

    Topics: Carbamazepine; Dystonia; Humans; Seizures

1979
Dystonia associated with carbamazepine administration: experience in brain-damaged children.
    Pediatrics, 1979, Volume: 63, Issue:4

    Topics: Carbamazepine; Child, Preschool; Dystonia; Humans; Infant; Male; Seizures

1979
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.
    European journal of pharmacology, 1991, Jan-10, Volume: 192, Issue:2

    Topics: Animals; Baclofen; Carbamazepine; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; gamma-Amin

1991
Dopa-responsive dystonia: long-term treatment response and prognosis.
    Neurology, 1991, Volume: 41, Issue:2 ( Pt 1)

    Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Depression; Dihydroxyphenylalanine; Disab

1991
Paroxysmal nocturnal dystonia presenting as excessive daytime somnolence.
    Archives of neurology, 1990, Volume: 47, Issue:3

    Topics: Adult; Carbamazepine; Diagnosis, Differential; Dystonia; Electroencephalography; Evaluation Studies

1990
Nocturnal paroxysmal dystonia with atypical short-lasting attacks.
    Neurophysiologie clinique = Clinical neurophysiology, 1990, Volume: 20, Issue:3

    Topics: Adolescent; Airway Obstruction; Animals; Carbamazepine; Circadian Rhythm; Dystonia; Humans; Male; Ra

1990
Nocturnal paroxysmal dystonia.
    Journal of neurology, neurosurgery, and psychiatry, 1986, Volume: 49, Issue:4

    Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Dystonia; Electroencephalography; Female; Humans; Hun

1986
Unusual idiosyncratic reactions to carbamazepine.
    Journal of neurology, neurosurgery, and psychiatry, 1988, Volume: 51, Issue:9

    Topics: Adolescent; Carbamazepine; Dystonia; Humans; Male; Middle Aged

1988
A long-lasting CBZ controlled case of hypnogenic paroxysmal dystonia.
    Italian journal of neurological sciences, 1988, Volume: 9, Issue:1

    Topics: Adult; Carbamazepine; Dystonia; Female; Humans; Sleep Wake Disorders

1988
Hypnogenic paroxysmal dystonia with panic attacks responsive to drug therapy.
    Psychosomatics, 1987, Volume: 28, Issue:5

    Topics: Adult; Anxiety Disorders; Carbamazepine; Dystonia; Fear; Female; Humans; Panic; Seizures; Syndrome

1987
Oculogyric crisis: a distinct toxic effect of carbamazepine.
    Journal of child neurology, 1986, Volume: 1, Issue:3

    Topics: Adult; Carbamazepine; Dystonia; Female; Fixation, Ocular; Humans; Seizures

1986
Familial paroxysmal hypnogenic dystonia.
    Neurology, 1985, Volume: 35, Issue:9

    Topics: Adult; Carbamazepine; Child; Dystonia; Female; Humans; Male; Sleep, REM

1985
Hypnogenic paroxysmal dystonia: epilepsy or sleep disorder? A case report.
    Clinical EEG (electroencephalography), 1985, Volume: 16, Issue:3

    Topics: Adult; Carbamazepine; Diazepam; Dystonia; Epilepsy; Humans; Male; Sleep; Sleep Wake Disorders; Syndr

1985