Page last updated: 2024-10-24

carbamazepine and Drug Overdose

carbamazepine has been researched along with Drug Overdose in 88 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"A proportion of patients undergoing epilepsy surgery, and receiving carbamazepine (CBZ), experience significant elevations in CBZ plasma concentrations, some with associated CBZ toxicity."9.11Risk factors for carbamazepine elevation and toxicity following epilepsy surgery. ( Bingaman, W; Hiremath, GK; Hovinga, C; Kotagal, P; Morris, H; Nelson, D; Wyllie, E, 2005)
"A 15-year-old female subject presented comatose, in respiratory failure and shock, after the intentional ingestion of ∼280 extended-release 200-mg carbamazepine tablets with a peak serum concentration of 138 µg/mL (583."7.85Combination Clearance Therapy and Barbiturate Coma for Severe Carbamazepine Overdose. ( Agulnik, A; Bruccoleri, R; Burns, MM; Ebrahimi-Fakhari, D; Kelly, DP; Kohane, DS; Sahin, M; Yuskaitis, C, 2017)
"An autopsy case of carbamazepine overdose with focal myocarditis is reported."7.73A case of carbamazepine overdose with focal myocarditis. ( Aoki, Y; Niitsu, H; Saigusa, K; Takamiya, M, 2006)
"We attributed the acute hyponatremia and seizures to the large increase in dose of carbamazepine in the presence of other risk factors for hyponatremia."7.73Carbamazepine-induced hyponatremia: assessment of risk factors. ( Kuz, GM; Manssourian, A, 2005)
"Serious complications after carbamazepine poisoning, such as coma, seizures, respiratory failure, cardiac conduction abnormalities, and death are more likely with serum levels greater than 170 micromol L(-1)."7.73Multidose activated charcoal in the treatment of carbamazepine overdose with seizures: a case report. ( Jukić, I; Mise, S; Titlić, M; Tonkić, A, 2005)
"We report two patients who experienced status epilepticus after carbamazepine overdose."7.71Status epilepticus after massive carbamazepine overdose. ( Carlisle, RD; Spiller, HA, 2002)
"We describe 2 cases of severe carbamazepine-associated left ventricular dysfunction during massive self intoxications in young patients without preexistent cardiac disease."7.70Carbamazepine-associated severe left ventricular dysfunction. ( Diehl, JL; Faisy, C; Guerot, E; Labrousse, J; Rezgui, N, 2000)
"Ophthalmoplegia is a rarely observed sign in carbamazepine and other anticonvulsant overdoses."5.28Complete external ophthalmoplegia and asterixis with carbamazepine toxicity. ( Edis, RH; Ng, K; Silbert, PL, 1991)
"A proportion of patients undergoing epilepsy surgery, and receiving carbamazepine (CBZ), experience significant elevations in CBZ plasma concentrations, some with associated CBZ toxicity."5.11Risk factors for carbamazepine elevation and toxicity following epilepsy surgery. ( Bingaman, W; Hiremath, GK; Hovinga, C; Kotagal, P; Morris, H; Nelson, D; Wyllie, E, 2005)
"Clinically significant side effects of the new anticonvulsants, such as metabolic acidosis from topiramate, autoimmune reactions from lamotrigine, hyponatremia from oxcarbazepine, or psychosis from levitiracetam can cause serious morbidity and mortality if unrecognized."4.86Emergent complications of the newer anticonvulsants. ( Dang, CV; Nelson, L; Wade, JF; Wasserberger, J, 2010)
"Carbamazepine (CBZ) is a common antiepileptic drug that may cause overdoses with seizures as a common neurological manifestation."4.12Stimulus-induced focal motor seizure in a pediatric patient with carbamazepine overdose. ( Fujimoto, A; Kanai, S; Maegaki, Y; Nakamura, Y; Ohta, K; Okanishi, T, 2022)
"A 15-year-old female subject presented comatose, in respiratory failure and shock, after the intentional ingestion of ∼280 extended-release 200-mg carbamazepine tablets with a peak serum concentration of 138 µg/mL (583."3.85Combination Clearance Therapy and Barbiturate Coma for Severe Carbamazepine Overdose. ( Agulnik, A; Bruccoleri, R; Burns, MM; Ebrahimi-Fakhari, D; Kelly, DP; Kohane, DS; Sahin, M; Yuskaitis, C, 2017)
"This article reports detoxication treatments of a case of combined overdose of carbamazepine and lithium in a 38-year-old female with bipolar disorder."3.74Detoxication treatment for carbamazepine and lithium overdose. ( Ikeda, H; Kihira, K; Murakami, T; Tanigawa, K; Unei, H, 2008)
"To report an interaction between carbamazepine and clarithromycin, we present a study that includes three regular attenders at the epilepsy department of Montpellier and seven cases reported by the French national drug safety center."3.74[Carbamazepine and clarithromycin: a clinically relevant drug interaction]. ( Coubes, P; Crespel, A; Gélisse, P; Halaili, E; Hillaire-Buys, D; Jean-Pastor, MJ; Vespignan, H, 2007)
"We attributed the acute hyponatremia and seizures to the large increase in dose of carbamazepine in the presence of other risk factors for hyponatremia."3.73Carbamazepine-induced hyponatremia: assessment of risk factors. ( Kuz, GM; Manssourian, A, 2005)
"An autopsy case of carbamazepine overdose with focal myocarditis is reported."3.73A case of carbamazepine overdose with focal myocarditis. ( Aoki, Y; Niitsu, H; Saigusa, K; Takamiya, M, 2006)
"Serious complications after carbamazepine poisoning, such as coma, seizures, respiratory failure, cardiac conduction abnormalities, and death are more likely with serum levels greater than 170 micromol L(-1)."3.73Multidose activated charcoal in the treatment of carbamazepine overdose with seizures: a case report. ( Jukić, I; Mise, S; Titlić, M; Tonkić, A, 2005)
"A 32-year-old epileptic patient with a lengthy history of multiple-drug abuse and psychotic disorders was found to have an elevated serum carbamazepine concentration of 40."3.73Hydroxyzine and metabolites as a source of interference in carbamazepine particle-enhanced turbidimetric inhibition immunoassay (PETINIA). ( Gagnieu, MC; Lardet, G; Moulsma, M; Parant, F, 2005)
"We report two patients who experienced status epilepticus after carbamazepine overdose."3.71Status epilepticus after massive carbamazepine overdose. ( Carlisle, RD; Spiller, HA, 2002)
"Unrecognized poisoning with controlled-release carbamazepine has the potential to produce significant delayed carbamazepine toxicity and delayed peak serum carbamazepine concentrations."3.71Massive overdose with controlled-release carbamazepine resulting in delayed peak serum concentrations and life-threatening toxicity. ( Dowsett, RP; Graudins, A; Peden, G, 2002)
"We report an 18-month-old comatose, convulsing child with plasma carbamazepine 27 microg/mL treated with high efficiency hemodialysis."3.70High-efficiency dialysis for carbamazepine overdose. ( Brophy, PD; Bunchman, TE; Kudelka, T; Maxvold, NJ; Schuerer, DJ, 2000)
"We describe 2 cases of severe carbamazepine-associated left ventricular dysfunction during massive self intoxications in young patients without preexistent cardiac disease."3.70Carbamazepine-associated severe left ventricular dysfunction. ( Diehl, JL; Faisy, C; Guerot, E; Labrousse, J; Rezgui, N, 2000)
"In 3rd day of treatment brain death was determined using clinical tests and instrumental confirmatory test (transcranial Doppler ultrasonography)."2.49[Acute poisonings and organ donation--case reports and literature review]. ( Klimaszyk, D; Łukasik-Głebocka, M, 2013)
"Carbamazepine is known to produce the side effect of euphoria."1.48A Clinical Study of Toxication Caused by Carbamazepine Abuse in Adolescents. ( Chen, YL; Li, JJ; Liu, CF; Wang, LJ; Xu, W; Zhao, Y, 2018)
"Oxcarbazepine (OXC) is a 10-keto analogue of carbamazepine used in patients with partial and secondary generalized seizures."1.43Thirteen years of oxcarbazepine exposures reported to US poison centers: 2000 to 2012. ( Burns, G; Essing-Spiller, SJ; Spiller, HA; Strauch, J, 2016)
" Our methodology allowed for a precise pharmacokinetic assessment of clearance based on total quantity of parent drug and active metabolite removed."1.43Carbamazepine and carbamazepine-10,11-epoxide clearance measurements during continuous venovenous hemofiltration in a massive overdose. ( Kearney, T; Petrie, MS; Smollin, CG, 2016)
"Carbamazepine (CBZ) is an antiepileptic drug used as a mood stabilizer in child psychiatry."1.42[Carbamazepine and psychotropic treatment interaction: Two case studies of carbamazepine overdosage]. ( Askenazy, F; Dor, E; Fernandez, A; Menard, ML; Thümmler, S, 2015)
"Carbamazepine overdose is a common, toxic ingestion, manifesting as central nervous system (CNS) and respiratory depression."1.40Successful treatment of severe carbamazepine toxicity with 5% albumin-enhanced continuous venovenous hemodialysis. ( Cole, M; Narayan, R; Rizzo, M, 2014)
"Drug overdose is a growing problem among adolescents."1.40Overdose with antiepileptic drugs: the efficacy of extracorporeal removal techniques. ( Dias, A; Estanqueiro, P; Farela Neves, J; Moinho, R, 2014)
"Carbamazepine (CBZ) is a commonly used antiepileptic agent."1.36Management of a severe carbamazepine overdose with continuous venovenous hemodiafiltration. ( Goktas, U; Kati, I; Yuce, HH, 2010)
"Carbamazepine is a widely used antiepileptic agent."1.34Carbamazepine poisoning managed with haemodialysis and haemoperfusion in three adolescents. ( Aydin, OF; Bek, K; Koçak, S; Ozkaya, O; Taşdöven, CS; Yilmaz, Y, 2007)
"Carbamazepine (CBZ) is an antiepileptic drug with tricyclic structure which implies its potential cardinotxic properties, especially in acute poisoning."1.34The influence of carbamazepine plasma level on blood pressure and some ECG parameters in patients with acute intoxication. ( Ciszowski, K; Jenner, B; Szpak, D, 2007)
"Carbamazepine was determined using FPIA method and phenothiazines derivatives by HPLC-DAD."1.34[Extended suicidal poisoning with carbamazepine and phenothiazine derivatives]. ( Gomółka, E; Hydzik, P; Wilimowska, J, 2007)
"In anticipation of coma, she is electively intubated to safely enable gastrointestinal decontamination with nasogastric activated charcoal."1.33Toxicology case of the month: Carbamazepine overdose. ( Daly, FF; Little, M; Murray, L; Soderstrom, J, 2006)
" Two hours after a documented overdosage of more than 100 tablets oxcarbazepine, the serum level of the parent compound was 10-fold higher than the therapeutic dosage (31."1.32Severe overdosage with the antiepileptic drug oxcarbazepine. ( Cilissen, J; De Heer, F; Janknegt, R; L'Ortije, WH; Nel, JE; van Opstal, JM, 2004)
"Unfortunately, the patient died from adult respiratory distress syndrome."1.31Continuous EEG monitoring in a patient with massive carbamazepine overdose. ( De Rubeis, DA; Young, GB, 2001)
"Other common signs are drowsiness and ataxia."1.31Signs and symptoms of carbamazepine overdose in young children. ( Gavrilov, V; Lifshitz, M; Sofer, S, 2000)
"Oral drug abuse is a major social and medical issue."1.30Recreational overdosage of carbamazepine in Paisley drug abusers. ( Crawford, PJ; Fisher, BM, 1997)
"We report a case of temporary sensorineural hearing loss in a patient after overdosing with 36 g of carbamazepine."1.30Carbamazepine-induced sensorineural hearing loss. ( Bance, M; de la Cruz, M, 1999)
"In those patients who recovered, coma, somnolence, cerebellar syndrome and epileptic seizures were the most common manifestations of CBZ overdose."1.29Signs and symptoms of carbamazepine overdose. ( Schmidt, S; Schmitz-Buhl, M, 1995)
" Diluted charcoal was administered through a nasogastric tube at a dose of 1 g/kg every 4 h, and a saline cathartic at the same dosage was administered every 12 h."1.29Carbamazepine poisoning in adolescent suicide attempters. Effectiveness of multiple-dose activated charcoal in enhancing carbamazepine elimination. ( Escalante-Galindo, P; Flores-Alvarez, E; Montoya-Cabrera, MA; Ruiz-Gómez, A; Sauceda-García, JM, 1996)
"Ophthalmoplegia is a rarely observed sign in carbamazepine and other anticonvulsant overdoses."1.28Complete external ophthalmoplegia and asterixis with carbamazepine toxicity. ( Edis, RH; Ng, K; Silbert, PL, 1991)
"Using the presence of coma, seizure activity or respiratory depression requiring mechanical ventilation as measures of toxicity, we found poor correlation between rising serum levels of carbamazepine and toxicity."1.28Carbamazepine overdose: a prospective study of serum levels and toxicity. ( Cookson, E; Krenzelok, EP; Spiller, HA, 1990)

Research

Studies (88)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.27)18.7374
1990's20 (22.73)18.2507
2000's43 (48.86)29.6817
2010's22 (25.00)24.3611
2020's1 (1.14)2.80

Authors

AuthorsStudies
Ohta, K1
Okanishi, T1
Kanai, S1
Nakamura, Y1
Fujimoto, A1
Maegaki, Y1
Agulnik, A1
Kelly, DP1
Bruccoleri, R1
Yuskaitis, C1
Ebrahimi-Fakhari, D1
Sahin, M1
Burns, MM2
Kohane, DS1
Xu, W1
Chen, YL1
Zhao, Y1
Wang, LJ1
Li, JJ1
Liu, CF1
Chung, YK1
Chang, KY1
Park, HS1
Kim, MH1
Lee, KM1
Lim, TS1
Kim, HW1
Narayan, R1
Rizzo, M1
Cole, M1
Klimaszyk, D1
Łukasik-Głebocka, M1
Ghannoum, M1
Yates, C1
Galvao, TF1
Sowinski, KM1
Vo, TH1
Coogan, A1
Gosselin, S1
Lavergne, V1
Nolin, TD1
Hoffman, RS1
Moinho, R1
Dias, A1
Estanqueiro, P1
Farela Neves, J1
Drick, N1
Patecki, M1
Arelin, V1
Schmidt, JJ1
Wahl, O1
Kielstein, JT1
Fernandez, A1
Dor, E1
Menard, ML1
Askenazy, F1
Thümmler, S1
Spiller, HA6
Strauch, J1
Essing-Spiller, SJ1
Burns, G1
Mittag, N1
Meister, S1
Berg, AM1
Walther, UI1
Smollin, CG1
Petrie, MS1
Kearney, T1
Tarnutzer, AA1
Imbach, LL1
Wade, JF1
Dang, CV1
Nelson, L1
Wasserberger, J1
Nixon, AC1
Doak, MW1
Crozier, H1
Crooks, DP1
Waring, WS1
Pedrini, M1
Noguera, A1
Vinent, J1
Torra, M1
Jiménez, R1
Goktas, U1
Kati, I1
Yuce, HH1
El Koraichi, A1
Mounir, K1
El Haddoury, M1
El Kettani, S1
Harder, JL1
Heung, M1
Vilay, AM1
Mueller, BA1
Segal, JH1
Azak, A1
Koçak, G1
Huddam, B1
Duranay, M1
Sikma, MA1
van den Broek, MP1
Meulenbelt, J1
Ozhasenekler, A1
Gökhan, S1
Güloğlu, C1
Orak, M1
Ustündağ, M1
Venci, JV1
Rowcliffe, MM1
Wollenberg, L1
Rainka, MM1
Gengo, FM1
Shah, S1
Tomlin, M1
Sparkes, D1
Isbister, GK1
Balit, CR1
Whyte, IM1
Dawson, A1
Raja, M1
Azzoni, A1
Askenazi, DJ1
Goldstein, SL1
Chang, IF1
Elenberg, E1
Feig, DI1
Barker, MJ1
Benitez, JG1
Ternullo, S1
Juhl, GA1
Osváth, P1
Fekete, S1
van Opstal, JM1
Janknegt, R1
Cilissen, J1
L'Ortije, WH1
Nel, JE1
De Heer, F1
Adams, BK1
Mann, MD1
Aboo, A1
Isaacs, S1
Evans, A1
Perez, A1
Wiley, JF1
Hiremath, GK1
Kotagal, P1
Bingaman, W1
Hovinga, C1
Wyllie, E1
Morris, H1
Nelson, D1
Parant, F1
Moulsma, M1
Gagnieu, MC1
Lardet, G1
Kuz, GM1
Manssourian, A1
Kołacński, Z1
Winnicka, R1
Lopaciński, B1
Kołacińska, M1
Mise, S2
Jukić, I1
Tonkić, A1
Titlić, M1
Furlanut, M1
Franceschi, L1
Poz, D1
Silvestri, L1
Pecorari, M1
Takamiya, M1
Aoki, Y1
Niitsu, H1
Saigusa, K1
Yildiz, TS1
Toprak, DG1
Arisoy, ES1
Solak, M1
Toker, K1
Soderstrom, J1
Murray, L1
Little, M1
Daly, FF1
Bek, K1
Koçak, S1
Ozkaya, O1
Yilmaz, Y1
Aydin, OF1
Taşdöven, CS1
Brahmi, N2
Lurie, Y1
Bentur, Y1
Levy, Y1
Baum, E1
Krivoy, N1
Ciszowski, K1
Szpak, D1
Jenner, B1
Hydzik, P1
Gomółka, E1
Wilimowska, J1
Livingston, S1
Pauli, LL1
Berman, W1
Gélisse, P1
Hillaire-Buys, D1
Halaili, E1
Jean-Pastor, MJ1
Vespignan, H1
Coubes, P1
Crespel, A1
Unei, H1
Ikeda, H1
Murakami, T1
Tanigawa, K1
Kihira, K1
Kouraichi, N1
Abderrazek, H1
Thabet, H1
Amamou, M1
Pilapil, M1
Petersen, J1
Schmidt, S1
Schmitz-Buhl, M1
Bridge, TA1
Norton, RL1
Robertson, WO1
Baischer, W1
Wagner, A1
Seidler, D1
Musalek, M1
Laggner, A1
Hojer, J1
Malmlund, HO1
Berg, A1
Krenzelok, EP2
Montoya-Cabrera, MA1
Sauceda-García, JM1
Escalante-Galindo, P1
Flores-Alvarez, E1
Ruiz-Gómez, A1
Parihar, PS1
Thussu, A1
Sharma, S1
Prabhakar, S1
Chan, TY1
Crawford, PJ1
Fisher, BM1
Bertram, M1
Fabian, CW1
Schwarz, S1
Schwab, S1
Young, CR1
Mazure, CM1
de la Cruz, M1
Bance, M1
Deshpande, G1
Meert, KL1
Valentini, RP1
Lifshitz, M1
Gavrilov, V1
Sofer, S1
Rösel, T1
Schneider, J1
Fischer, JT1
Druschky, KF1
Matos, ME1
Shannon, MW1
Schuerer, DJ1
Brophy, PD1
Maxvold, NJ1
Kudelka, T1
Bunchman, TE1
Faisy, C1
Guerot, E1
Diehl, JL1
Rezgui, N1
Labrousse, J1
Habib, GS1
Cohen, L1
Fleischman, A1
Chiang, VW1
Grünewald, RA1
Mack, CJ1
De Rubeis, DA1
Young, GB1
Carlisle, RD2
Milonovich, LM1
Headrick, CL1
Seikaly, M1
Morriss, FC1
Wood, SP1
Graudins, A1
Peden, G1
Dowsett, RP1
Edge, W1
Edmonds, J1
Vale, JA1
Heath, A1
Wason, S1
Baker, RC1
Carolan, P1
Seigel, R1
Druckenbrod, RW1
Ng, K1
Silbert, PL1
Edis, RH1
Coulter, F1
Corrigan, FM1
Dalkin, T1
Lee, AS1
Cookson, E1
Begley, JP1

Reviews

5 reviews available for carbamazepine and Drug Overdose

ArticleYear
[Acute poisonings and organ donation--case reports and literature review].
    Przeglad lekarski, 2013, Volume: 70, Issue:8

    Topics: Adult; Brain Death; Carbamazepine; Drug Overdose; Fatal Outcome; Humans; Insulin; Kidney Transplanta

2013
Extracorporeal treatment for carbamazepine poisoning: systematic review and recommendations from the EXTRIP workgroup.
    Clinical toxicology (Philadelphia, Pa.), 2014, Volume: 52, Issue:10

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Consensus; Delphi Techni

2014
Emergent complications of the newer anticonvulsants.
    The Journal of emergency medicine, 2010, Volume: 38, Issue:2

    Topics: Acidosis; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Overdose; Fructo

2010
Packaging of drugs and the risk of severe toxicity in adult self-poisonings.
    Journal of clinical pharmacy and therapeutics, 1997, Volume: 22, Issue:3

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Carbamazepine; Drug Overdose; Drug Packaging; Hong K

1997
Management of carbamazepine overdose.
    Pediatric emergency care, 2001, Volume: 17, Issue:6

    Topics: Anticonvulsants; Arrhythmias, Cardiac; Carbamazepine; Child; Drug Overdose; Hemoperfusion; Humans; S

2001

Trials

1 trial available for carbamazepine and Drug Overdose

ArticleYear
Risk factors for carbamazepine elevation and toxicity following epilepsy surgery.
    Seizure, 2005, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Body Weight; Carbamazepine; Child; Child, Preschool

2005

Other Studies

82 other studies available for carbamazepine and Drug Overdose

ArticleYear
Stimulus-induced focal motor seizure in a pediatric patient with carbamazepine overdose.
    Brain & development, 2022, Volume: 44, Issue:10

    Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Drug Overdose; Epilepsies, Partial; Female;

2022
Combination Clearance Therapy and Barbiturate Coma for Severe Carbamazepine Overdose.
    Pediatrics, 2017, Volume: 139, Issue:5

    Topics: Adolescent; Barbiturates; Carbamazepine; Coma; Combined Modality Therapy; Decontamination; Drug Over

2017
A Clinical Study of Toxication Caused by Carbamazepine Abuse in Adolescents.
    BioMed research international, 2018, Volume: 2018

    Topics: Adolescent; Carbamazepine; Child; Coma; Drug Overdose; Female; Humans; Male; Renal Dialysis; Respira

2018
Severe carbamazepine intoxication unresponsive to albumin-enhanced continuous venovenous hemodiafiltration with low dialysate flow.
    Hemodialysis international. International Symposium on Home Hemodialysis, 2014, Volume: 18, Issue:2

    Topics: Adolescent; Albumins; Anticonvulsants; Carbamazepine; Charcoal; Dialysis Solutions; Drug Overdose; H

2014
Successful treatment of severe carbamazepine toxicity with 5% albumin-enhanced continuous venovenous hemodialysis.
    Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2014, Volume: 17, Issue:2

    Topics: Adult; Albumins; Antimanic Agents; Carbamazepine; Drug Overdose; Female; Hemodialysis Solutions; Hum

2014
Overdose with antiepileptic drugs: the efficacy of extracorporeal removal techniques.
    BMJ case reports, 2014, Nov-24, Volume: 2014

    Topics: Adolescent; Anticonvulsants; Antidotes; Carbamazepine; Charcoal; Combined Modality Therapy; Drug Ove

2014
[Successful hemodialysis for life-threatening carbamazepine drug overdose: Case-based introduction of new guidelines].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2015, Volume: 110, Issue:7

    Topics: Adult; Carbamazepine; Combined Modality Therapy; Critical Care; Delayed-Action Preparations; Drug Ov

2015
[Carbamazepine and psychotropic treatment interaction: Two case studies of carbamazepine overdosage].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2015, Volume: 22, Issue:5

    Topics: Adolescent; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Drug Overdose; Drug

2015
Thirteen years of oxcarbazepine exposures reported to US poison centers: 2000 to 2012.
    Human & experimental toxicology, 2016, Volume: 35, Issue:10

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Overdose; Drug-Rela

2016
A Case Report of a Carbamazepine Overdose With Focus on Pharmacokinetic Aspects.
    Pharmacopsychiatry, 2016, Volume: 49, Issue:2

    Topics: Carbamazepine; Charcoal; Drug Monitoring; Drug Overdose; Humans; Male; Middle Aged

2016
Carbamazepine and carbamazepine-10,11-epoxide clearance measurements during continuous venovenous hemofiltration in a massive overdose.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:5

    Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Overdose; Female;

2016
The intoxicated EEG.
    Seizure, 2017, Volume: 45

    Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Drug Overdose; Drug Resistant Epilepsy; Electroencepha

2017
Patterns of antiepileptic drug overdose differ between men and women: admissions to the Edinburgh Poisons Unit, 2000-2007.
    QJM : monthly journal of the Association of Physicians, 2009, Volume: 102, Issue:1

    Topics: Adult; Anticonvulsants; Carbamazepine; Drug Overdose; Female; Humans; Lamotrigine; Male; Middle Aged

2009
Acute oxcarbazepine overdose in an autistic boy.
    British journal of clinical pharmacology, 2009, Volume: 67, Issue:5

    Topics: Adolescent; Anticonvulsants; Autistic Disorder; Carbamazepine; Drug Overdose; Humans; Male; Oxcarbaz

2009
Management of a severe carbamazepine overdose with continuous venovenous hemodiafiltration.
    The American journal of emergency medicine, 2010, Volume: 28, Issue:2

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Coma; Drug Overdose; Female; Hemodiafiltration; Humans;

2010
[Management of carbamazepine overdose in pediatric intensive care unit].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2011, Volume: 18, Issue:1

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Drug Overdose; Female; Humans; Intensive Care Units, Ped

2011
Carbamazepine and the active epoxide metabolite are effectively cleared by hemodialysis followed by continuous venovenous hemodialysis in an acute overdose.
    Hemodialysis international. International Symposium on Home Hemodialysis, 2011, Volume: 15, Issue:3

    Topics: Adult; Analgesics, Non-Narcotic; Carbamazepine; Drug Overdose; Half-Life; Humans; Male; Renal Dialys

2011
Is conventional hemodialysis enough to manage carbamazepine intoxication?.
    Blood purification, 2012, Volume: 33, Issue:4

    Topics: Adult; Anticonvulsants; Carbamazepine; Charcoal; Drug Overdose; Female; Humans; Pregnancy; Renal Dia

2012
Increased unbound drug fraction in acute carbamazepine intoxication: suitability and effectiveness of high-flux haemodialysis.
    Intensive care medicine, 2012, Volume: 38, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Fema

2012
Benefit of hemodialysis in carbamazepine intoxications with neurological complications.
    European review for medical and pharmacological sciences, 2012, Volume: 16 Suppl 1

    Topics: Adult; Anticonvulsants; Antidotes; Carbamazepine; Charcoal; Drug Overdose; Female; Gastric Lavage; G

2012
Pharmacokinetic simulation of fatal carbamazepine intoxication in 23-month old child following phenytoin discontinuation.
    Forensic science, medicine, and pathology, 2013, Volume: 9, Issue:1

    Topics: Anticonvulsants; Autopsy; Biotransformation; Carbamazepine; Computer Simulation; Drug Administration

2013
Lack of effect of high-volume continuous veno-venous haemofiltration with dialysis in massive carbamazepine overdose.
    BMJ case reports, 2012, Oct-12, Volume: 2012

    Topics: Adult; Antimanic Agents; Carbamazepine; Cardiotonic Agents; Drug Overdose; Fluid Therapy; Hemofiltra

2012
Valproate overdose: a comparative cohort study of self poisonings.
    British journal of clinical pharmacology, 2003, Volume: 55, Issue:4

    Topics: Adult; Analysis of Variance; Anticonvulsants; Carbamazepine; Cohort Studies; Critical Care; Drug Ove

2003
Oxcarbazepine, risperidone and atenolol overdose with benign outcome.
    The international journal of neuropsychopharmacology, 2003, Volume: 6, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Alcoholism; Anticonvulsants; Antipsychotic Agents; Atenolol; Bip

2003
Management of a severe carbamazepine overdose using albumin-enhanced continuous venovenous hemodialysis.
    Pediatrics, 2004, Volume: 113, Issue:2

    Topics: Anticonvulsants; Carbamazepine; Child; Drug Overdose; Female; Hemofiltration; Humans

2004
Acute oxcarbazepine and atomoxetine overdose with quetiapine.
    Veterinary and human toxicology, 2004, Volume: 46, Issue:3

    Topics: Adult; Antipsychotic Agents; Atomoxetine Hydrochloride; Carbamazepine; Diagnosis, Differential; Dibe

2004
[Characteristics of the choice of psychotropic drugs in suicide attempts].
    Orvosi hetilap, 2003, Jan-19, Volume: 144, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antidepressive Agents; Antipsychotic Agents

2003
Severe overdosage with the antiepileptic drug oxcarbazepine.
    British journal of clinical pharmacology, 2004, Volume: 58, Issue:3

    Topics: Adult; Anticonvulsants; Carbamazepine; Drug Overdose; Epilepsy; Humans; Male; Oxcarbazepine

2004
Prolonged gastric emptying half-time and gastric hypomotility after drug overdose.
    The American journal of emergency medicine, 2004, Volume: 22, Issue:7

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anticonvulsant

2004
Pediatric carbamazepine suspension overdose-clinical manifestations and toxicokinetics.
    Pediatric emergency care, 2005, Volume: 21, Issue:4

    Topics: Administration, Oral; Anticonvulsants; Carbamazepine; Child, Preschool; Drug Overdose; Emergency Med

2005
Hydroxyzine and metabolites as a source of interference in carbamazepine particle-enhanced turbidimetric inhibition immunoassay (PETINIA).
    Therapeutic drug monitoring, 2005, Volume: 27, Issue:4

    Topics: Adult; Anticonvulsants; Carbamazepine; Cross Reactions; Drug Monitoring; Drug Overdose; Epilepsy; Hi

2005
Carbamazepine-induced hyponatremia: assessment of risk factors.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:11

    Topics: Acute Disease; Adult; Anticonvulsants; Carbamazepine; Drug Overdose; Epilepsy, Tonic-Clonic; Female;

2005
[Carbamazepine "CR"--clinical picture of intoxication: the kinetics of extracorporeal elimination].
    Przeglad lekarski, 2005, Volume: 62, Issue:6

    Topics: Adult; Anticonvulsants; Carbamazepine; Charcoal; Drug Overdose; Half-Life; Hemoperfusion; Humans; Ma

2005
Multidose activated charcoal in the treatment of carbamazepine overdose with seizures: a case report.
    Arhiv za higijenu rada i toksikologiju, 2005, Volume: 56, Issue:4

    Topics: Adult; Anticonvulsants; Carbamazepine; Charcoal; Drug Overdose; Humans; Intubation, Gastrointestinal

2005
Acute oxcarbazepine, benazepril, and hydrochlorothiazide overdose with alcohol.
    Therapeutic drug monitoring, 2006, Volume: 28, Issue:2

    Topics: Anticonvulsants; Antihypertensive Agents; Benzazepines; Carbamazepine; Critical Care; Diuretics; Dru

2006
A case of carbamazepine overdose with focal myocarditis.
    Legal medicine (Tokyo, Japan), 2006, Volume: 8, Issue:4

    Topics: Adult; Antimanic Agents; Bipolar Disorder; Carbamazepine; Drug Overdose; Female; Humans; Lymphocytes

2006
Continuous venovenous hemodiafiltration to treat controlled-release carbamazepine overdose in a pediatric patient.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:11

    Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Delayed-Action Preparations; Drug Overdose; Hemodi

2006
Toxicology case of the month: Carbamazepine overdose.
    Emergency medicine journal : EMJ, 2006, Volume: 23, Issue:11

    Topics: Adult; Anticonvulsants; Australia; Carbamazepine; Charcoal; Coma; Drug Overdose; Emergencies; Emerge

2006
Carbamazepine poisoning managed with haemodialysis and haemoperfusion in three adolescents.
    Nephrology (Carlton, Vic.), 2007, Volume: 12, Issue:1

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Charcoal; Child; Drug Overdose; Female; Hemoperfusion; H

2007
Reply to Multiple-dose activated charcoal in carbamazepine poisoning.
    The American journal of emergency medicine, 2007, Volume: 25, Issue:4

    Topics: Anticonvulsants; Antidotes; Carbamazepine; Charcoal; Dose-Response Relationship, Drug; Drug Overdose

2007
Limited efficacy of gastrointestinal decontamination in severe slow-release carbamazepine overdose.
    The Annals of pharmacotherapy, 2007, Volume: 41, Issue:9

    Topics: Adult; Antidotes; Antimanic Agents; Carbamazepine; Charcoal; Decontamination; Drug Overdose; Humans;

2007
The influence of carbamazepine plasma level on blood pressure and some ECG parameters in patients with acute intoxication.
    Przeglad lekarski, 2007, Volume: 64, Issue:4-5

    Topics: Acute Disease; Adolescent; Adult; Antidepressive Agents, Tricyclic; Blood Flow Velocity; Blood Press

2007
[Extended suicidal poisoning with carbamazepine and phenothiazine derivatives].
    Przeglad lekarski, 2007, Volume: 64, Issue:4-5

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Central Nervous System Depressants; Drug Overdose

2007
Carbamazepine (Tegretol) in epilepsy. Nine year follow-up study with special emphasis on untoward reactions.
    Diseases of the nervous system, 1974, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Carbamazepine; Child; Diplopia; Drug Overd

1974
[Carbamazepine and clarithromycin: a clinically relevant drug interaction].
    Revue neurologique, 2007, Volume: 163, Issue:11

    Topics: Adult; Aged; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Clarithromycin; Cytochrome P-450

2007
Detoxication treatment for carbamazepine and lithium overdose.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2008, Volume: 128, Issue:1

    Topics: Adult; Bayes Theorem; Bipolar Disorder; Carbamazepine; Charcoal; Drug Overdose; Female; Gastric Lava

2008
Clinical experience with carbamazepine overdose: relationship between serum concentration and neurological severity.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:2

    Topics: Adult; Carbamazepine; Coma; Drug Overdose; Female; Humans; Male; Nervous System Diseases; Retrospect

2008
Efficacy of hemodialysis and charcoal hemoperfusion in carbamazepine overdose.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:4

    Topics: Adult; Antimanic Agents; Carbamazepine; Charcoal; Drug Overdose; Female; Hemoperfusion; Humans; Rena

2008
Signs and symptoms of carbamazepine overdose.
    Journal of neurology, 1995, Volume: 242, Issue:3

    Topics: Adolescent; Adult; Carbamazepine; Cerebellar Diseases; Coma; Drug Overdose; Epilepsy; Female; Humans

1995
Pediatric carbamazepine overdoses.
    Pediatric emergency care, 1994, Volume: 10, Issue:5

    Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Overdose;

1994
[Carbamazepine poisoning: protracted course with development of intestinal atony and hepatic toxicity].
    Wiener klinische Wochenschrift, 1994, Volume: 106, Issue:1

    Topics: Adult; Bipolar Disorder; Carbamazepine; Chemical and Drug Induced Liver Injury; Coma; Drug Overdose;

1994
Clinical features in 28 consecutive cases of laboratory confirmed massive poisoning with carbamazepine alone.
    Journal of toxicology. Clinical toxicology, 1993, Volume: 31, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbamazepine; Drug Overdose; Female; Glasgow Coma Scale

1993
Carbamazepine overdose: serum concentration less predictive in children.
    Journal of toxicology. Clinical toxicology, 1993, Volume: 31, Issue:3

    Topics: Adult; Carbamazepine; Child; Child, Preschool; Drug Overdose; Humans; Infant; Predictive Value of Te

1993
Carbamazepine poisoning in adolescent suicide attempters. Effectiveness of multiple-dose activated charcoal in enhancing carbamazepine elimination.
    Archives of medical research, 1996,Winter, Volume: 27, Issue:4

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Cardiovascular System; Charcoal; Depression; Drug Overdo

1996
Carbamazepine induced sino-atrial block in a young adult.
    The Journal of the Association of Physicians of India, 1996, Volume: 44, Issue:6

    Topics: Adult; Anticonvulsants; Carbamazepine; Cardiac Pacing, Artificial; Dose-Response Relationship, Drug;

1996
Recreational overdosage of carbamazepine in Paisley drug abusers.
    Scottish medical journal, 1997, Volume: 42, Issue:2

    Topics: Adult; Carbamazepine; Drug Overdose; Humans; Male; Scotland; Substance-Related Disorders; Temazepam

1997
Massive carbamazepine overdose: clinical and neurophysiological findings.
    Journal of neurology, 1998, Volume: 245, Issue:11

    Topics: Adult; Anticonvulsants; Carbamazepine; Central Nervous System; Diagnosis, Differential; Drug Overdos

1998
Fulminant hepatic failure from acetaminophen in an anorexic patient treated with carbamazepine.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:11

    Topics: Acetaminophen; Adolescent; Anorexia Nervosa; Carbamazepine; Drug Overdose; Drug Synergism; Drug Ther

1998
Carbamazepine-induced sensorineural hearing loss.
    Archives of otolaryngology--head & neck surgery, 1999, Volume: 125, Issue:2

    Topics: Adult; Anticonvulsants; Carbamazepine; Drug Overdose; Female; Hearing Loss, Bilateral; Hearing Loss,

1999
Repeat charcoal hemoperfusion treatments in life threatening carbamazepine overdose.
    Pediatric nephrology (Berlin, Germany), 1999, Volume: 13, Issue:9

    Topics: Carbamazepine; Charcoal; Drug Overdose; Female; Hemoperfusion; Humans; Infant; Time Factors

1999
Signs and symptoms of carbamazepine overdose in young children.
    Pediatric emergency care, 2000, Volume: 16, Issue:1

    Topics: Anticonvulsants; Ataxia; Carbamazepine; Child, Preschool; Drug Overdose; Female; Humans; Male; Nysta

2000
[Carbamazepine poisoning caused by confusing the drugs].
    Deutsche medizinische Wochenschrift (1946), 2000, Mar-24, Volume: 125, Issue:12

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cerebral Infarction; Diagnosis, Differential; Drug Over

2000
False-positive tricyclic antidepressant drug screen results leading to the diagnosis of carbamazepine intoxication.
    Pediatrics, 2000, Volume: 105, Issue:5

    Topics: Adolescent; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Child; Drug Overdose;

2000
High-efficiency dialysis for carbamazepine overdose.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:3

    Topics: Anticonvulsants; Carbamazepine; Coma; Drug Overdose; Humans; Infant; Renal Dialysis; Seizures; Treat

2000
Carbamazepine-associated severe left ventricular dysfunction.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:3

    Topics: Adult; Antimanic Agents; Carbamazepine; Cardiotonic Agents; Dobutamine; Drug Overdose; Echocardiogra

2000
Pulmonary edema complicating carbamazepine overdose.
    The Israel Medical Association journal : IMAJ, 2000, Volume: 2, Issue:7

    Topics: Adult; Carbamazepine; Drug Overdose; Humans; Male; Pulmonary Edema

2000
Carbamazepine overdose recognized by a tricyclic antidepressant assay.
    Pediatrics, 2001, Volume: 107, Issue:1

    Topics: Adolescent; Antidepressive Agents, Tricyclic; Carbamazepine; Drug Interactions; Drug Overdose; False

2001
Medical errors. Different formulations of drugs often look confusingly similar.
    BMJ (Clinical research ed.), 2001, Jun-09, Volume: 322, Issue:7299

    Topics: Anticonvulsants; Carbamazepine; Dosage Forms; Drug Industry; Drug Overdose; Drug Packaging; Humans

2001
Continuous EEG monitoring in a patient with massive carbamazepine overdose.
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2001, Volume: 18, Issue:2

    Topics: Adult; Brain; Carbamazepine; Coma; Drug Overdose; Electroencephalography; Epilepsy, Tonic-Clonic; Fa

2001
Timely antemortem and postmortem concentrations in a fatal carbamazepine overdose.
    Journal of forensic sciences, 2001, Volume: 46, Issue:6

    Topics: Absorption; Adult; Amobarbital; Anticonvulsants; Carbamazepine; Drug Overdose; Fatal Outcome; Female

2001
Charcoal hemoperfusion via a continuous venovenous hemofiltration circuit to treat carbamazepine overdose.
    Critical care nurse, 2001, Volume: 21, Issue:6

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Charcoal; Drug Overdose; Female; Hemofiltration; Hemoper

2001
Use of charcoal hemoperfusion.
    Critical care nurse, 2002, Volume: 22, Issue:2

    Topics: Carbamazepine; Charcoal; Drug Overdose; Hemoperfusion; Humans

2002
Status epilepticus after massive carbamazepine overdose.
    Journal of toxicology. Clinical toxicology, 2002, Volume: 40, Issue:1

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Drug Overdose; Fatal Outcome; Female; Humans; Hypnotics

2002
Massive overdose with controlled-release carbamazepine resulting in delayed peak serum concentrations and life-threatening toxicity.
    Emergency medicine (Fremantle, W.A.), 2002, Volume: 14, Issue:1

    Topics: Adult; Carbamazepine; Critical Illness; Delayed-Action Preparations; Drug Overdose; Emergency Servic

2002
Serum sodium and carbamazepine overdose.
    Journal of toxicology. Clinical toxicology, 1992, Volume: 30, Issue:3

    Topics: Carbamazepine; Child, Preschool; Drug Overdose; Humans; Hyponatremia; Male; Seizures; Sodium

1992
Carbamazepine overdose.
    Journal of toxicology. Clinical toxicology, 1992, Volume: 30, Issue:3

    Topics: Blood; Carbamazepine; Charcoal; Drug Overdose; Humans

1992
Carbamazepine overdose--the effects of multiple dose activated charcoal.
    Journal of toxicology. Clinical toxicology, 1992, Volume: 30, Issue:1

    Topics: Acute Disease; Adolescent; Carbamazepine; Charcoal; Child, Preschool; Chronic Disease; Dose-Response

1992
Complete external ophthalmoplegia and asterixis with carbamazepine toxicity.
    Australian and New Zealand journal of medicine, 1991, Volume: 21, Issue:6

    Topics: Carbamazepine; Drug Interactions; Drug Overdose; Erythromycin; Female; Humans; Middle Aged; Ophthalm

1991
Carbamazepine and NMS.
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 158

    Topics: Carbamazepine; Dose-Response Relationship, Drug; Drug Overdose; Humans; Neuroleptic Malignant Syndro

1991
Carbamazepine and forme fruste neuroleptic malignant syndrome.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 157

    Topics: Bipolar Disorder; Body Temperature; Carbamazepine; Drug Overdose; Drug Therapy, Combination; Female;

1990
Carbamazepine overdose: a prospective study of serum levels and toxicity.
    Journal of toxicology. Clinical toxicology, 1990, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Child, Preschool; Coma; Drug Overdose; Humans;

1990
Pulmonary oedema after carbamazepine overdose.
    Anaesthesia, 1989, Volume: 44, Issue:9

    Topics: Carbamazepine; Drug Overdose; Humans; Pulmonary Edema

1989