carbamazepine has been researched along with Delayed Effects, Prenatal Exposure in 79 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our objective was to evaluate the patterns of malformations in children exposed in utero to phenytoin (DPH) and carbamazepine (CBZ) monotherapy, and to compare them prospectively with matched mother-child pairs exposed to nonteratogens, and to separate the effects of antiepileptic drugs (AEDs) from those of epilepsy by collecting groups of untreated epileptics and those treated with DPH and CBZ for conditions other than epilepsy." | 9.08 | Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications. ( Chitayat, D; Farkas, LD; Koren, G; Nulman, I; Scolnik, D, 1997) |
| "Oxcarbazepine is an antiepileptic agent that has been used during pregnancy, although its safety during pregnancy has not been sufficiently established." | 7.79 | In utero oxcarbazepine and a withdrawal syndrome, anomalies, and hyponatremia. ( Klinger, G; Merlob, P; Rolnitsky, A, 2013) |
| "A boy, born to an epileptic mother who had been treated with carbamazepine monotherapy throughout pregnancy and breast feeding, experienced asphyxia at birth with transient hepatic dysfunction in the first week of life." | 7.71 | Neonatal cholestatic hepatitis from carbamazepine exposure during pregnancy and breast feeding. ( Braegger, CP; Frey, B; Ghelfi, D, 2002) |
| "In utero exposure to carbamazepine may result in 'carbamazepine syndrome' characterised by facial dysmorphic features and mild mental retardation." | 7.69 | Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy. ( Cohen, E; Ornoy, A, 1996) |
| "We report a 3-week-old boy with cholestatic hepatitis, most likely due to carbamazepine exposure during pregnancy and breastfeeding." | 7.68 | Transient cholestatic hepatitis in a neonate associated with carbamazepine exposure during pregnancy and breast-feeding. ( Frey, B; Musy, JP; Schubiger, G, 1990) |
| "Oxcarbazepine is a second-generation antiepileptic drug that is used to treat partial seizures." | 6.55 | In Utero Oxcarbazepine Exposure and Neonatal Abstinence Syndrome: Case Report and Brief Review of the Literature. ( Chen, CY; Cui, YM; Feng, Q; Li, X; Ma, LY; Wu, PH; Zhou, Y, 2017) |
| "Our objective was to evaluate the patterns of malformations in children exposed in utero to phenytoin (DPH) and carbamazepine (CBZ) monotherapy, and to compare them prospectively with matched mother-child pairs exposed to nonteratogens, and to separate the effects of antiepileptic drugs (AEDs) from those of epilepsy by collecting groups of untreated epileptics and those treated with DPH and CBZ for conditions other than epilepsy." | 5.08 | Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications. ( Chitayat, D; Farkas, LD; Koren, G; Nulman, I; Scolnik, D, 1997) |
| " Oxcarbazepine and lamotrigine were associated with increased occurrence of autism." | 4.95 | Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta-analysis. ( Cogo, E; D'Souza, J; Finkelstein, Y; Hemmelgarn, BR; Hutton, B; Kealey, R; MacDonald, H; Reynen, E; Rios, P; Soobiah, C; Straus, SE; Thavorn, K; Tricco, AC; Veroniki, AA; Yazdi, F, 2017) |
| "The developmental quotient (DQ) was lower in children exposed to carbamazepine (CBZ) (n = 50) than in children born to women without epilepsy (n = 79); mean difference (MD) of -5." | 4.90 | Treatment for epilepsy in pregnancy: neurodevelopmental outcomes in the child. ( Adab, N; Bromley, R; Greenhalgh, J; Marson, AG; McKay, AJ; Sanniti, A; Tudur Smith, C; Weston, J, 2014) |
| "To identify specific major congenital malformations associated with use of carbamazepine in the first trimester of pregnancy." | 4.86 | Intrauterine exposure to carbamazepine and specific congenital malformations: systematic review and case-control study. ( de Jong-van den Berg, L; Dolk, H; Garne, E; Jentink, J; Loane, MA; Morris, JK; Wellesley, D, 2010) |
| " Those born to mothers with prescription of antiseizure medications other than carbamazepine during pregnancy were excluded." | 4.31 | Prenatal Carbamazepine Exposure and Academic Performance in Adolescents: A Population-Based Cohort Study. ( Lee, PMY; Li, F; Li, J; Ren, T, 2023) |
| "Findings from this explorative study strengthen the evidence for the warning against the use of valproate in pregnancy and raise concern of risks of specific psychiatric disorders associated with topiramate and levetiracetam." | 4.31 | Prenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders. ( Alvestad, S; Bjørk, MH; Christensen, J; Cohen, JM; Dreier, JW; Furu, K; Gissler, M; Igland, J; Leinonen, MK; Sun, Y; Tomson, T; Zoega, H, 2023) |
| "Oxcarbazepine is an antiepileptic agent that has been used during pregnancy, although its safety during pregnancy has not been sufficiently established." | 3.79 | In utero oxcarbazepine and a withdrawal syndrome, anomalies, and hyponatremia. ( Klinger, G; Merlob, P; Rolnitsky, A, 2013) |
| "We present a case of a woman who used topiramate (100 mg) and oxcarbazepine (300 mg) continuously during pregnancy." | 3.78 | Multiple fetal anomalies in association with topiramate and oxcarbezepine treatment. ( Aksoy, F; Aydin, Y; Bakkaloglu, D; Sen, C; Uludag, S; Yilmaz, O, 2012) |
| "To determine the frequency of malformations among infants born to women who had taken lamotrigine or carbamazepine as part of polytherapy during the first trimester of pregnancy." | 3.77 | Fetal effects of anticonvulsant polytherapies: different risks from different drug combinations. ( Hernandez-Diaz, S; Holmes, LB; Mittendorf, R; Shen, A; Smith, CR, 2011) |
| " Between 1999 and 2004, we enrolled pregnant women with epilepsy who were taking a single AED (carbamazepine, lamotrigine, phenytoin, or valproate)." | 3.76 | Effects of breastfeeding in children of women taking antiepileptic drugs. ( Baker, GA; Browning, N; Clayton-Smith, J; Cohen, M; Combs-Cantrell, DT; Kalayjian, LA; Kanner, A; Liporace, JD; Loring, DW; Meador, KJ; Pennell, PB; Privitera, M, 2010) |
| "Between 1999 and 2004, we enrolled pregnant women with epilepsy who were taking a single antiepileptic agent (carbamazepine, lamotrigine, phenytoin, or valproate) in a prospective, observational, multicenter study in the United States and the United Kingdom." | 3.75 | Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs. ( Baker, GA; Browning, N; Clayton-Smith, J; Cohen, M; Combs-Cantrell, DT; Kalayjian, LA; Kanner, A; Liporace, JD; Loring, DW; Meador, KJ; Pennell, PB; Privitera, M, 2009) |
| "This substudy of the Neurodevelopmental Effects of Antiepileptic Drugs investigation enrolled pregnant women with epilepsy on AED monotherapy (carbamazepine, lamotrigine, and valproate)." | 3.75 | A prospective study of cognitive fluency and originality in children exposed in utero to carbamazepine, lamotrigine, or valproate monotherapy. ( Gaillard, WD; McVearry, KM; Meador, KJ; VanMeter, J, 2009) |
| "(1) Numerous follow-up studies of pregnancies in women with epilepsy show that valproic acid is more teratogenic than other antiepileptics." | 3.75 | Valproic acid: long-term effects on children exposed in utero. ( , 2009) |
| "Children exposed during pregnancy to the anticonvulsant drugs phenytoin, phenobarbital, and carbamazepine as monotherapy and polytherapy have an increased frequency of midface and digit hypoplasia." | 3.73 | The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs. ( Coull, BA; Dorfman, J; Holmes, LB; Rosenberger, PB, 2005) |
| "To investigate the effect of antiepileptic drugs, especially carbamazepine and valproate, on intelligence in prenatally exposed children of mothers with epilepsy." | 3.72 | Normal intelligence in children with prenatal exposure to carbamazepine. ( Bardy, A; Gaily, E; Granström, ML; Hiilesmaa, V; Isoaho, M; Kaaja, E; Kantola-Sorsa, E; Kotila, M; Matila, R; Nylund, T, 2004) |
| "A boy, born to an epileptic mother who had been treated with carbamazepine monotherapy throughout pregnancy and breast feeding, experienced asphyxia at birth with transient hepatic dysfunction in the first week of life." | 3.71 | Neonatal cholestatic hepatitis from carbamazepine exposure during pregnancy and breast feeding. ( Braegger, CP; Frey, B; Ghelfi, D, 2002) |
| "The purpose of this study was to determine if there are any correlations between carbamazepine serum levels of epileptic mothers during pregnancy and the brainstem auditory evoked potentials in their infants as an index of drug neurotoxicity in newborns exposed prenatally." | 3.71 | Effects of prenatal exposure to carbamazepine on brainstem auditory evoked potentials in infants of epileptic mothers. ( Belmont, A; Garza, S; Ibarra, J; López, V; Poblano, A; Rosas, Y; Sosa, J, 2002) |
| "We selected all subjects who enrolled in the California Teratogen Information Service (CTIS) pregnancy outcome study for prenatal exposure to carbamazepine or valproic acid between 1990 and 1997 and who received prenatal care through Kaiser Permanente of Southern California (n = 13)." | 3.71 | Selection bias in Teratology Information Service pregnancy outcome studies. ( Chambers, CD; Johnson, KA; Jones, KL; Weber, PA, 2001) |
| "We present an uncommon severe first branchial arch congenital malformation, in which complete unilateral bony fusion between the maxillary and mandibular processes was found in a newborn exposed to carbamazepine medication all through pregnancy." | 3.70 | Congenital unilateral fusion of the maxilla and mandible. ( Haddad, IK; Salah, S; Shamo'on, H, 1999) |
| "Twenty epileptic women were treated with valproate only during pregnancy and two were treated with valproate and carbamazepine." | 3.70 | Neonatal hypoglycaemia and withdrawal symptoms after exposure in utero to valproate. ( Ebbesen, F; Holsteen, V; Hoseth, E; Joergensen, A; Kaad, PH; Moeller, M; Rix, M, 2000) |
| "In utero exposure to carbamazepine may result in 'carbamazepine syndrome' characterised by facial dysmorphic features and mild mental retardation." | 3.69 | Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy. ( Cohen, E; Ornoy, A, 1996) |
| "To compare pregnancy outcome prospectively after phenytoin and carbamazepine monotherapy with outcome in matched mother-child pairs exposed to nonteratogens to evaluate the relative fetal safety of these drugs." | 3.69 | Neurodevelopment of children exposed in utero to phenytoin and carbamazepine monotherapy. ( Ashby, P; Czuchta, D; Einarson, T; Gardner, HA; Gladstone, D; Gladstone, R; Nulman, I; Rovet, J; Scolnik, D; Weksberg, R, 1994) |
| "We report a 3-week-old boy with cholestatic hepatitis, most likely due to carbamazepine exposure during pregnancy and breastfeeding." | 3.68 | Transient cholestatic hepatitis in a neonate associated with carbamazepine exposure during pregnancy and breast-feeding. ( Frey, B; Musy, JP; Schubiger, G, 1990) |
| " Fifty-two children had been exposed to phenytoin monotherapy, 19 to carbamazepine monotherapy, 27 to drug combinations including barbiturates, 29 to other drug combinations, and 17 children had not been exposed to antiepileptic drugs (AEDs) during pregnancy." | 3.68 | Head circumference in children of epileptic mothers: contributions of drug exposure and genetic background. ( Bardy, AH; Gaily, EK; Granström, ML; Hiilesmaa, VK, 1990) |
| "Oxcarbazepine is a second-generation antiepileptic drug that is used to treat partial seizures." | 2.55 | In Utero Oxcarbazepine Exposure and Neonatal Abstinence Syndrome: Case Report and Brief Review of the Literature. ( Chen, CY; Cui, YM; Feng, Q; Li, X; Ma, LY; Wu, PH; Zhou, Y, 2017) |
| "To study the risk of intellectual disability and delayed development in childhood milestones among children of women who used valproate or other AEDs during pregnancy." | 1.56 | Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Intellectual Disability and Delayed Childhood Milestones. ( Christensen, J; Daugaard, CA; Dreier, JW; Pedersen, L; Sun, Y, 2020) |
| " The numerical density of Leydig cells and hormone dosage were obtained." | 1.40 | Carbamazepine-exposure during gestation and lactation affects pubertal onset and spermatic parameters in male pubertal offspring. ( Andretta, RR; de Oliva, SU; Miraglia, SM; Okada, FK; Paccola, CC; Stumpp, T, 2014) |
| " Carbamazepine (CBZ) and phenobarbital (PHB) during pregnancy should be used at the lowest dosage compatible with maternal disease." | 1.34 | Unilateral multicystic dysplastic kidney in infants exposed to antiepileptic drugs during pregnancy. ( Carta, M; Cimador, M; Corsello, G; De Grazia, E; Di Pace, MR; Giuffrè, M; Sergio, M, 2007) |
| " However, there is no information available on the number of therapeutic abortions, or the different types of epilepsy or drug dosage in the two treatment groups." | 1.32 | Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study. ( Källén, B; Wide, K; Winbladh, B, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.53) | 18.7374 |
| 1990's | 11 (13.92) | 18.2507 |
| 2000's | 23 (29.11) | 29.6817 |
| 2010's | 34 (43.04) | 24.3611 |
| 2020's | 9 (11.39) | 2.80 |
| Authors | Studies |
|---|---|
| Bjørk, MH | 3 |
| Zoega, H | 2 |
| Leinonen, MK | 2 |
| Cohen, JM | 2 |
| Dreier, JW | 3 |
| Furu, K | 2 |
| Gilhus, NE | 2 |
| Gissler, M | 2 |
| Hálfdánarson, Ó | 1 |
| Igland, J | 2 |
| Sun, Y | 3 |
| Tomson, T | 4 |
| Alvestad, S | 2 |
| Christensen, J | 4 |
| Ren, T | 1 |
| Lee, PMY | 1 |
| Li, F | 1 |
| Li, J | 2 |
| Husebye, ESN | 1 |
| Spigset, O | 1 |
| Daltveit, AK | 1 |
| Huber-Mollema, Y | 2 |
| van Iterson, L | 1 |
| Oort, FJ | 2 |
| Lindhout, D | 5 |
| Rodenburg, R | 2 |
| Clark, CT | 1 |
| Wiggs, KK | 1 |
| Rickert, ME | 1 |
| Sujan, AC | 1 |
| Quinn, PD | 1 |
| Larsson, H | 1 |
| Lichtenstein, P | 1 |
| Oberg, AS | 1 |
| D'Onofrio, BM | 1 |
| Daugaard, CA | 1 |
| Pedersen, L | 1 |
| Kakumoto, M | 1 |
| Shimokawa, K | 1 |
| Ueshima, S | 1 |
| Hira, D | 1 |
| Okano, T | 1 |
| Chen, CY | 1 |
| Li, X | 1 |
| Ma, LY | 1 |
| Wu, PH | 1 |
| Zhou, Y | 1 |
| Feng, Q | 1 |
| Cui, YM | 1 |
| Veroniki, AA | 1 |
| Rios, P | 1 |
| Cogo, E | 1 |
| Straus, SE | 1 |
| Finkelstein, Y | 1 |
| Kealey, R | 1 |
| Reynen, E | 1 |
| Soobiah, C | 1 |
| Thavorn, K | 1 |
| Hutton, B | 1 |
| Hemmelgarn, BR | 1 |
| Yazdi, F | 1 |
| D'Souza, J | 1 |
| MacDonald, H | 1 |
| Tricco, AC | 1 |
| Galappatthy, P | 1 |
| Liyanage, CK | 1 |
| Lucas, MN | 1 |
| Jayasekara, DTLM | 1 |
| Abhayaratna, SA | 1 |
| Weeraratne, C | 1 |
| De Abrew, K | 1 |
| Gunaratne, PS | 1 |
| Gamage, R | 1 |
| Wijeyaratne, CN | 1 |
| Barton, S | 1 |
| Nadebaum, C | 1 |
| Anderson, VA | 1 |
| Vajda, F | 2 |
| Reutens, DC | 1 |
| Wood, AG | 1 |
| Cohen, MJ | 2 |
| Meador, KJ | 7 |
| May, R | 1 |
| Loblein, H | 1 |
| Conrad, T | 1 |
| Baker, GA | 6 |
| Bromley, RL | 3 |
| Clayton-Smith, J | 7 |
| Kalayjian, LA | 4 |
| Kanner, A | 3 |
| Liporace, JD | 3 |
| Pennell, PB | 4 |
| Privitera, M | 3 |
| Loring, DW | 5 |
| Richards, N | 1 |
| Reith, D | 1 |
| Stitely, M | 1 |
| Smith, A | 1 |
| Yang, F | 1 |
| Yuan, W | 1 |
| Liang, H | 1 |
| Song, X | 1 |
| Yu, Y | 1 |
| Gelaye, B | 1 |
| Miao, M | 1 |
| Giménez, A | 1 |
| Pacchiarotti, I | 1 |
| Gil, J | 1 |
| Murru, A | 1 |
| Gomes, SP | 1 |
| Pinzón, JE | 1 |
| Anmella, G | 1 |
| Gómez-Ramiro, M | 1 |
| Verdolini, N | 1 |
| Valentí, M | 1 |
| Goikolea, JM | 1 |
| Vieta, E | 1 |
| Rolnitsky, A | 1 |
| Merlob, P | 1 |
| Klinger, G | 1 |
| Andretta, RR | 1 |
| Okada, FK | 1 |
| Paccola, CC | 1 |
| Stumpp, T | 1 |
| de Oliva, SU | 1 |
| Miraglia, SM | 1 |
| Åberg, E | 1 |
| Holst, S | 1 |
| Neagu, A | 1 |
| Ögren, SO | 1 |
| Lavebratt, C | 1 |
| Verrotti, A | 1 |
| Scaparrotta, A | 1 |
| Cofini, M | 1 |
| Chiarelli, F | 1 |
| Tiboni, GM | 1 |
| Bromley, R | 2 |
| Weston, J | 1 |
| Adab, N | 2 |
| Greenhalgh, J | 1 |
| Sanniti, A | 1 |
| McKay, AJ | 1 |
| Tudur Smith, C | 1 |
| Marson, AG | 1 |
| Briggs, M | 2 |
| Cheyne, CP | 1 |
| García-Fiñana, M | 2 |
| Gummery, A | 1 |
| Kneen, R | 2 |
| Mawer, G | 2 |
| Shallcross, R | 2 |
| Klein, P | 1 |
| Pelizzo, G | 1 |
| Calcaterra, V | 1 |
| Mannarino, S | 1 |
| Moramarco, LP | 1 |
| Leati, G | 1 |
| Quaretti, P | 1 |
| Homberg, V | 1 |
| Lavi-Blau, T | 1 |
| Ekstein, D | 1 |
| Neufeld, MY | 1 |
| Eyal, S | 1 |
| Hirashima, R | 1 |
| Michimae, H | 1 |
| Takemoto, H | 1 |
| Sasaki, A | 1 |
| Kobayashi, Y | 1 |
| Itoh, T | 1 |
| Tukey, RH | 1 |
| Fujiwara, R | 1 |
| Thomas, RH | 1 |
| Robertson, NP | 1 |
| Würtz, AM | 1 |
| Rytter, D | 1 |
| Vestergaard, CH | 1 |
| Vestergaard, M | 1 |
| Bech, BH | 1 |
| Browning, N | 2 |
| Combs-Cantrell, DT | 2 |
| Cohen, M | 2 |
| McVearry, KM | 1 |
| Gaillard, WD | 1 |
| VanMeter, J | 1 |
| Nulman, I | 3 |
| Jentink, J | 1 |
| Dolk, H | 1 |
| Loane, MA | 1 |
| Morris, JK | 1 |
| Wellesley, D | 1 |
| Garne, E | 1 |
| de Jong-van den Berg, L | 1 |
| Cummings, C | 1 |
| Stewart, M | 1 |
| Stevenson, M | 1 |
| Morrow, J | 1 |
| Nelson, J | 1 |
| Battino, D | 1 |
| Bonizzoni, E | 1 |
| Craig, J | 1 |
| Sabers, A | 1 |
| Perucca, E | 1 |
| Holmes, LB | 2 |
| Mittendorf, R | 1 |
| Shen, A | 1 |
| Smith, CR | 1 |
| Hernandez-Diaz, S | 1 |
| Kulaga, S | 1 |
| Sheehy, O | 1 |
| Zargarzadeh, AH | 1 |
| Moussally, K | 1 |
| Bérard, A | 1 |
| Uludag, S | 1 |
| Aydin, Y | 1 |
| Yilmaz, O | 1 |
| Aksoy, F | 1 |
| Bakkaloglu, D | 1 |
| Sen, C | 1 |
| Smith, AK | 1 |
| Conneely, KN | 1 |
| Newport, DJ | 1 |
| Kilaru, V | 1 |
| Schroeder, JW | 1 |
| Knight, BT | 1 |
| Cubells, JC | 1 |
| Stowe, ZN | 1 |
| Brennan, PA | 1 |
| Mawer, GE | 1 |
| Cheyne, C | 1 |
| Lucas, SB | 1 |
| Poblano, A | 1 |
| Belmont, A | 1 |
| Sosa, J | 1 |
| Ibarra, J | 1 |
| Rosas, Y | 1 |
| López, V | 1 |
| Garza, S | 1 |
| Smyth, MD | 1 |
| Barbaro, NM | 1 |
| Baraban, SC | 1 |
| Kaaja, E | 2 |
| Kaaja, R | 1 |
| Hiilesmaa, V | 2 |
| Gaily, E | 1 |
| Kantola-Sorsa, E | 1 |
| Isoaho, M | 1 |
| Matila, R | 1 |
| Kotila, M | 1 |
| Nylund, T | 1 |
| Bardy, A | 1 |
| Granström, ML | 2 |
| Christensen, HD | 2 |
| Rayburn, WF | 2 |
| Parker, KM | 2 |
| Gonzalez, CL | 2 |
| Gold, KP | 1 |
| Wide, K | 1 |
| Winbladh, B | 1 |
| Källén, B | 1 |
| Yonkers, KA | 1 |
| Wisner, KL | 1 |
| Stowe, Z | 1 |
| Leibenluft, E | 1 |
| Cohen, L | 1 |
| Miller, L | 1 |
| Manber, R | 1 |
| Viguera, A | 1 |
| Suppes, T | 1 |
| Altshuler, L | 1 |
| Shorvon, SD | 1 |
| Coull, BA | 1 |
| Dorfman, J | 1 |
| Rosenberger, PB | 1 |
| Kini, U | 1 |
| Vinten, J | 1 |
| Fryer, A | 1 |
| Ducray, F | 1 |
| Colin, P | 1 |
| Cartalat-Carel, S | 1 |
| Pelissou-Guyotat, I | 1 |
| Mahla, K | 1 |
| Audra, P | 1 |
| Gaucherand, P | 1 |
| Honnorat, J | 1 |
| Trouillas, P | 1 |
| Rezvani, M | 1 |
| Koren, G | 2 |
| Viinikainen, K | 1 |
| Eriksson, K | 1 |
| Mönkkönen, A | 1 |
| Aikiä, M | 1 |
| Nieminen, P | 1 |
| Heinonen, S | 1 |
| Kälviäinen, R | 1 |
| Narang, M | 1 |
| Shah, D | 1 |
| Natasha, G | 1 |
| Carta, M | 1 |
| Cimador, M | 1 |
| Giuffrè, M | 1 |
| Sergio, M | 1 |
| Di Pace, MR | 1 |
| De Grazia, E | 1 |
| Corsello, G | 1 |
| Sereno Colo, JA | 1 |
| Domínguez Chavez, FJ | 1 |
| Núñez Gutiérrez, J | 1 |
| Höppener, RJ | 1 |
| Meinardi, H | 1 |
| Scolnik, D | 2 |
| Rovet, J | 1 |
| Gladstone, D | 1 |
| Czuchta, D | 1 |
| Gardner, HA | 1 |
| Gladstone, R | 1 |
| Ashby, P | 1 |
| Weksberg, R | 1 |
| Einarson, T | 1 |
| Jeret, JS | 1 |
| Thompson, WO | 1 |
| Omtzigt, JG | 1 |
| Los, FJ | 1 |
| Meijer, JW | 1 |
| Phillips, NK | 1 |
| Lockard, JS | 1 |
| Chitayat, D | 1 |
| Farkas, LD | 1 |
| Ornoy, A | 1 |
| Cohen, E | 1 |
| Haddad, IK | 1 |
| Shamo'on, H | 1 |
| Salah, S | 1 |
| Ebbesen, F | 1 |
| Joergensen, A | 1 |
| Hoseth, E | 1 |
| Kaad, PH | 1 |
| Moeller, M | 1 |
| Holsteen, V | 1 |
| Rix, M | 1 |
| Johnson, KA | 1 |
| Weber, PA | 1 |
| Jones, KL | 1 |
| Chambers, CD | 1 |
| Gupta, G | 1 |
| Bansal, A | 1 |
| Singh, M | 1 |
| Frey, B | 2 |
| Braegger, CP | 1 |
| Ghelfi, D | 1 |
| van der Pol, MC | 1 |
| Hadders-Algra, M | 1 |
| Huisjes, HJ | 1 |
| Touwen, BC | 1 |
| Schubiger, G | 1 |
| Musy, JP | 1 |
| Gaily, EK | 1 |
| Hiilesmaa, VK | 1 |
| Bardy, AH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822] | 550 participants (Anticipated) | Observational | 2022-02-18 | Recruiting | |||
| Effects and Consequences for Mother and Child From Treatment for Depression, A Prospective Randomized, Placebo- Controlled, Trial With Internet-based Cognitive Behavior Therapy and Sertraline or Placebo for Moderate Depression in Pregnancy[NCT02185547] | Phase 4 | 17 participants (Actual) | Interventional | 2016-02-21 | Terminated (stopped due to Difficulties in recruiting participants.) | ||
| A Preliminary Study of the Efficacy and Safety of Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency[NCT01379469] | Phase 2 | 20 participants (Actual) | Interventional | 2012-01-31 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for carbamazepine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Psychotropic drug use in perinatal women with bipolar disorder.
Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Drug Elimination Routes; Fe | 2020 |
In Utero Oxcarbazepine Exposure and Neonatal Abstinence Syndrome: Case Report and Brief Review of the Literature.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Male; Neonatal Abstinence Sy | 2017 |
Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta-analysis.
Topics: Anticonvulsants; Autistic Disorder; Bayes Theorem; Breast Feeding; Carbamazepine; Child; Epilepsy; F | 2017 |
Adverse outcomes during pregnancy and major congenital malformations in infants of patients with bipolar and schizoaffective disorders treated with antiepileptic drugs: A systematic review.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Bipolar Disorder; Carbamazepine; Female; Humans | 2019 |
Developmental neurotoxicity and anticonvulsant drugs: a possible link.
Topics: Animals; Anticonvulsants; Breast Feeding; Carbamazepine; Cognition Disorders; Developmental Disabili | 2014 |
Treatment for epilepsy in pregnancy: neurodevelopmental outcomes in the child.
Topics: Age Factors; Anticonvulsants; Carbamazepine; Child; Developmental Disabilities; Epilepsy; Female; Hu | 2014 |
Intrauterine exposure to carbamazepine and specific congenital malformations: systematic review and case-control study.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Case-Control Studies; Epilepsy; Europe; | 2010 |
Management of bipolar disorder during pregnancy and the postpartum period.
Topics: Adolescent; Adult; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbam | 2004 |
Does vitamin K prophylaxis prevent bleeding in neonates exposed to enzyme-inducing antiepileptic drugs in utero?
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Pregnancy; Prenatal Exposure Delaye | 2006 |
1 trial available for carbamazepine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications.
Topics: Adult; Carbamazepine; Cohort Studies; Craniofacial Abnormalities; Epilepsy; Female; Fingers; Humans; | 1997 |
69 other studies available for carbamazepine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability.
Topics: Anticonvulsants; Autism Spectrum Disorder; Autistic Disorder; Carbamazepine; Child; Cohort Studies; | 2022 |
Prenatal Carbamazepine Exposure and Academic Performance in Adolescents: A Population-Based Cohort Study.
Topics: Academic Performance; Adolescent; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Cohort Stu | 2023 |
Prenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders.
Topics: Adolescent; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Carbamazepine; Child; Ch | 2023 |
Language impairment in children aged 5 and 8 years after antiepileptic drug exposure in utero - the Norwegian Mother and Child Cohort Study.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cohort Studies; Epilepsy; Female; Humans; L | 2020 |
Neurocognition after prenatal levetiracetam, lamotrigine, carbamazepine or valproate exposure.
Topics: Anticonvulsants; Carbamazepine; Child; Child Development; Cognitive Dysfunction; Female; Humans; Lam | 2020 |
Antiseizure medication use during pregnancy and risk of ASD and ADHD in children.
Topics: Adolescent; Adult; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Autism Spectrum D | 2020 |
Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Intellectual Disability and Delayed Childhood Milestones.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Denmark; Developmen | 2020 |
Effects of antiepileptic drugs' administration during pregnancy on the nerve cell proliferation and axonal outgrowth of human neuroblastoma SH-SY5Y nerve cells.
Topics: Anticonvulsants; Carbamazepine; Cell Line, Tumor; Cell Proliferation; Child; Epilepsy; Female; Human | 2021 |
Obstetric outcomes and effects on babies born to women treated for epilepsy during pregnancy in a resource limited setting: a comparative cohort study.
Topics: Abortion, Spontaneous; Adolescent; Adult; Anticonvulsants; Body Height; Body Weight; Carbamazepine; | 2018 |
Memory dysfunction in school-aged children exposed prenatally to antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsy; Female; Hu | 2018 |
Fetal antiepileptic drug exposure and learning and memory functioning at 6 years of age: The NEAD prospective observational study.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Lamotrigine; Learning; Memor | 2019 |
Developmental outcomes at age four following maternal antiepileptic drug use.
Topics: Adult; Anticonvulsants; Carbamazepine; Child Development; Child, Preschool; Cohort Studies; Epilepsy | 2019 |
Preconceptional paternal antiepileptic drugs use and risk of congenital anomalies in offspring: a nationwide cohort study.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cohort Studies; Denmark; Epilepsy; F | 2019 |
Behavioral problems in children of mothers with epilepsy prenatally exposed to valproate, carbamazepine, lamotrigine, or levetiracetam monotherapy.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child Behavior Disorders; Epilepsy; Female; Humans; La | 2019 |
In utero oxcarbazepine and a withdrawal syndrome, anomalies, and hyponatremia.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Hyponatremia; Infant; Oxcarbazepine; Pregn | 2013 |
Carbamazepine-exposure during gestation and lactation affects pubertal onset and spermatic parameters in male pubertal offspring.
Topics: Animals; Anticonvulsants; Carbamazepine; Estradiol; Female; Lactation; Luteinizing Hormone; Male; Ma | 2014 |
Prenatal exposure to carbamazepine reduces hippocampal and cortical neuronal cell population in new-born and young mice without detectable effects on learning and memory.
Topics: Amygdala; Animals; Carbamazepine; Cerebral Cortex; Female; Hippocampus; Immunohistochemistry; Learni | 2013 |
IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child Development; Epilepsy; Female; Humans; Intellige | 2015 |
Fine-tuning risk assessment with antiepileptic drug use in pregnancy.
Topics: Anticonvulsants; Carbamazepine; Child Development; Epilepsy; Female; Humans; Intelligence; Lamotrigi | 2015 |
Valproate and pregnancy: think again.
Topics: Anticonvulsants; Carbamazepine; Child Development; Epilepsy; Female; Humans; Intelligence; Lamotrigi | 2015 |
Aortopulmonary collateral artery in prenatal exposure to carbamazepine - endovascular therapy and technical considerations: a case report.
Topics: Anticonvulsants; Aorta; Carbamazepine; Child; Embolization, Therapeutic; Female; Heart Defects, Cong | 2015 |
[Valproic acid responsible for low IQ].
Topics: Anticonvulsants; Carbamazepine; Child Development; Epilepsy; Female; Humans; Intelligence; Male; Pre | 2015 |
Fine-tuning risk assessment with antiepileptic drug use in pregnancy.
Topics: Anticonvulsants; Carbamazepine; Child Development; Epilepsy; Female; Humans; Intelligence; Male; Pre | 2015 |
Use of antiepileptic drugs during pregnancy and lactation: Type of information provided by searching Google.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans | 2016 |
Induction of the UDP-Glucuronosyltransferase 1A1 during the Perinatal Period Can Cause Neurodevelopmental Toxicity.
Topics: Animals; Animals, Newborn; Brain; Carbamazepine; Cell Movement; Enzyme Induction; Female; Gene Expre | 2016 |
The consequences of valproate exposure in utero.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Prenatal Exposure Delayed Effects; Valproic Acid | 2016 |
Prenatal exposure to antiepileptic drugs and use of primary healthcare during childhood: a population-based cohort study in Denmark.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Denmark; Epilepsy; Femal | 2017 |
Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child, Preschool; Cognition; Developmental Disabilities; Dose | 2009 |
A prospective study of cognitive fluency and originality in children exposed in utero to carbamazepine, lamotrigine, or valproate monotherapy.
Topics: Analysis of Variance; Anticonvulsants; Carbamazepine; Child, Preschool; Cognition; Creativity; Epile | 2009 |
Valproic acid: long-term effects on children exposed in utero.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Contraindications; Dose | 2009 |
Effects of breastfeeding in children of women taking antiepileptic drugs.
Topics: Adult; Anticonvulsants; Breast Feeding; Carbamazepine; Child, Preschool; Cognition; Epilepsy; Female | 2010 |
Carbamazepine in pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newbo | 2010 |
Neurodevelopment of children exposed in utero to lamotrigine, sodium valproate and carbamazepine.
Topics: Anticonvulsants; Carbamazepine; Case-Control Studies; Child, Preschool; Developmental Disabilities; | 2011 |
Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epile | 2011 |
Fetal effects of anticonvulsant polytherapies: different risks from different drug combinations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Canada; Carbamazepine; Cohort Studies; Drug Therapy, C | 2011 |
Antiepileptic drug use during pregnancy: perinatal outcomes.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Cohort Studies; Drug | 2011 |
Multiple fetal anomalies in association with topiramate and oxcarbezepine treatment.
Topics: Abnormalities, Multiple; Adult; Anticonvulsants; Carbamazepine; Female; Fetus; Fructose; Humans; Oxc | 2012 |
Prenatal antiepileptic exposure associates with neonatal DNA methylation differences.
Topics: Anticonvulsants; Carbamazepine; CpG Islands; Depressive Disorder, Major; DNA Methylation; Drug Evalu | 2012 |
The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Child Development Disorders, Per | 2013 |
Effects of prenatal exposure to carbamazepine on brainstem auditory evoked potentials in infants of epileptic mothers.
Topics: Adult; Anticonvulsants; Carbamazepine; Embryonic and Fetal Development; Epilepsy; Evoked Potentials, | 2002 |
Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Carbamazepine; Disea | 2002 |
Major malformations in offspring of women with epilepsy.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Comorbidity; Educational Status; | 2003 |
Normal intelligence in children with prenatal exposure to carbamazepine.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy; | 2004 |
Chronic prenatal exposure to carbamazepine and perinatal outcomes of C3H/He mice.
Topics: Animals; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Female; Mice | 2004 |
Chronic prenatal exposure to carbamazepine and behavior effects on mice offspring.
Topics: Animals; Anticonvulsants; Arousal; Carbamazepine; Cognition; Female; Mice; Mice, Inbred C3H; Motivat | 2004 |
Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study.
Topics: Abnormalities, Multiple; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fetal Diseases; Hu | 2004 |
Longer term outcome of children born to mothers with epilepsy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Fema | 2004 |
The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cognition Disorders; Face; Facie | 2005 |
Dysmorphic features: an important clue to the diagnosis and severity of fetal anticonvulsant syndromes.
Topics: Abnormalities, Drug-Induced; Adolescent; Anthropometry; Anticonvulsants; Carbamazepine; Child; Child | 2006 |
[Management of malignant gliomas diagnosed during pregnancy].
Topics: Abortion, Therapeutic; Adrenal Cortex Hormones; Adult; Algorithms; Anesthesia, General; Antineoplast | 2006 |
The effects of valproate exposure in utero on behavior and the need for educational support in school-aged children.
Topics: Anticonvulsants; Carbamazepine; Child; Cognition; Education, Special; Epilepsy; Female; Humans; Ment | 2006 |
Intracranial arteriovenous malformation with maternal carbamazepine use.
Topics: Adult; Carbamazepine; Cerebral Angiography; Fatal Outcome; Female; Humans; Infant; Intracranial Arte | 2007 |
Unilateral multicystic dysplastic kidney in infants exposed to antiepileptic drugs during pregnancy.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Follow-Up Studies; Humans; Infant, Newborn; Matern | 2007 |
[Treatment of pregnant epileptics with carbamazepine. Preliminary report].
Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Epilepsy; Female; Humans; Pregnancy; Pregnancy Co | 1984 |
Teratogenicity of antiepileptic drug combinations with special emphasis on epoxidation (of carbamazepine).
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Therapy, | 1984 |
Neurodevelopment of children exposed in utero to phenytoin and carbamazepine monotherapy.
Topics: Carbamazepine; Case-Control Studies; Child; Cognition; Developmental Disabilities; Female; Humans; I | 1994 |
Neurodevelopment after in utero exposure to phenytoin and carbamazepine.
Topics: Carbamazepine; Child; Developmental Disabilities; Female; Humans; Phenytoin; Pregnancy; Prenatal Exp | 1994 |
Neurodevelopment after in utero exposure to phenytoin and carbamazepine.
Topics: Carbamazepine; Child; Developmental Disabilities; Female; Humans; Phenytoin; Pregnancy; Prenatal Exp | 1994 |
The 10,11-epoxide-10,11-diol pathway of carbamazepine in early pregnancy in maternal serum, urine, and amniotic fluid: effect of dose, comedication, and relation to outcome of pregnancy.
Topics: Abnormalities, Drug-Induced; Amniotic Fluid; Carbamazepine; Cohort Studies; Dose-Response Relationsh | 1993 |
Infant monkey hyperexcitability after prenatal exposure to antiepileptic compounds.
Topics: Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Carbamazepine; Dioxolanes; Disease Mod | 1996 |
Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy.
Topics: Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Child Development; Child, Preschool; Cr | 1996 |
Congenital unilateral fusion of the maxilla and mandible.
Topics: Anticonvulsants; Branchial Region; Carbamazepine; Dose-Response Relationship, Drug; Fatal Outcome; F | 1999 |
Neonatal hypoglycaemia and withdrawal symptoms after exposure in utero to valproate.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Hypoglycemia; I | 2000 |
Selection bias in Teratology Information Service pregnancy outcome studies.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; California; Carbamazepine; Drug Information Ser | 2001 |
Antenatal carbamazepine use associated with d-TGA and ASD.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Heart Septal Defects, Atrial; Humans; Infan | 2002 |
Neonatal cholestatic hepatitis from carbamazepine exposure during pregnancy and breast feeding.
Topics: Breast Feeding; Carbamazepine; Chemical and Drug Induced Liver Injury; Cholestasis; Epilepsy; Female | 2002 |
Antiepileptic medication in pregnancy: late effects on the children's central nervous system development.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Central Nervous System; Child; Child De | 1991 |
Transient cholestatic hepatitis in a neonate associated with carbamazepine exposure during pregnancy and breast-feeding.
Topics: Breast Feeding; Carbamazepine; Chemical and Drug Induced Liver Injury; Epilepsy; Female; Humans; Inf | 1990 |
Head circumference in children of epileptic mothers: contributions of drug exposure and genetic background.
Topics: Adult; Anticonvulsants; Carbamazepine; Child, Preschool; Epilepsy; Female; Humans; Intelligence Test | 1990 |