Page last updated: 2024-10-24

carbamazepine and Craniofacial Abnormalities

carbamazepine has been researched along with Craniofacial Abnormalities in 4 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Craniofacial Abnormalities: Congenital structural deformities, malformations, or other abnormalities of the cranium and facial bones.

Research Excerpts

ExcerptRelevanceReference
"Our objective was to evaluate the patterns of malformations in children exposed in utero to phenytoin (DPH) and carbamazepine (CBZ) monotherapy, and to compare them prospectively with matched mother-child pairs exposed to nonteratogens, and to separate the effects of antiepileptic drugs (AEDs) from those of epilepsy by collecting groups of untreated epileptics and those treated with DPH and CBZ for conditions other than epilepsy."9.08Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications. ( Chitayat, D; Farkas, LD; Koren, G; Nulman, I; Scolnik, D, 1997)
" The boy was exposed to phenytoin, in combination with carbamazepine, during pregnancy."7.71Chondrodysplasia punctata (CDP) with features of the tibia-metacarpal type and maternal phenytoin treatment during pregnancy. ( Annerén, G; Brandberg, G; Larsson, M; Lönnerholm, T; Wester, U, 2002)
"The purpose of the study was to assess whether there was an increased rate of congenital anomalies or significant developmental delay in infants of women with epilepsy who had been treated with carbamazepine during pregnancy."7.69Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy. ( Cohen, E; Ornoy, A, 1996)
"Our objective was to evaluate the patterns of malformations in children exposed in utero to phenytoin (DPH) and carbamazepine (CBZ) monotherapy, and to compare them prospectively with matched mother-child pairs exposed to nonteratogens, and to separate the effects of antiepileptic drugs (AEDs) from those of epilepsy by collecting groups of untreated epileptics and those treated with DPH and CBZ for conditions other than epilepsy."5.08Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications. ( Chitayat, D; Farkas, LD; Koren, G; Nulman, I; Scolnik, D, 1997)
" The boy was exposed to phenytoin, in combination with carbamazepine, during pregnancy."3.71Chondrodysplasia punctata (CDP) with features of the tibia-metacarpal type and maternal phenytoin treatment during pregnancy. ( Annerén, G; Brandberg, G; Larsson, M; Lönnerholm, T; Wester, U, 2002)
"The purpose of the study was to assess whether there was an increased rate of congenital anomalies or significant developmental delay in infants of women with epilepsy who had been treated with carbamazepine during pregnancy."3.69Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy. ( Cohen, E; Ornoy, A, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wester, U1
Brandberg, G1
Larsson, M1
Lönnerholm, T1
Annerén, G1
Kessler, H1
Kraft, S1
Nulman, I1
Scolnik, D1
Chitayat, D1
Farkas, LD1
Koren, G1
Ornoy, A1
Cohen, E1

Reviews

1 review available for carbamazepine and Craniofacial Abnormalities

ArticleYear
[Neuropsychiatric symptoms in Sotos syndrome. Case report and review of the literature].
    Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater, 2008, Volume: 22, Issue:1

    Topics: Adult; Antipsychotic Agents; Brain; Carbamazepine; Chromosome Deletion; Citalopram; Compulsive Behav

2008

Trials

1 trial available for carbamazepine and Craniofacial Abnormalities

ArticleYear
Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications.
    American journal of medical genetics, 1997, Jan-10, Volume: 68, Issue:1

    Topics: Adult; Carbamazepine; Cohort Studies; Craniofacial Abnormalities; Epilepsy; Female; Fingers; Humans;

1997

Other Studies

2 other studies available for carbamazepine and Craniofacial Abnormalities

ArticleYear
Chondrodysplasia punctata (CDP) with features of the tibia-metacarpal type and maternal phenytoin treatment during pregnancy.
    Prenatal diagnosis, 2002, Volume: 22, Issue:8

    Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Chondrodysplasia Punctata; Craniofacial Abnormalit

2002
Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy.
    Archives of disease in childhood, 1996, Volume: 75, Issue:6

    Topics: Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Child Development; Child, Preschool; Cr

1996