carbamazepine and Convulsions, Grand Mal studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Research Excerpts

Excerpt	Relevance	Reference
"To review the best evidence comparing phenobarbitone and phenytoin when used as monotherapy in participants with partial onset seizures or generalised tonic-clonic seizures with or without other generalised seizure types."	8.89	Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures. ( Marson, AG; Nolan, SJ; Pulman, J; Tudur Smith, C, 2013)
"This study aimed to assess efficacy and safety of oxcarbazepine (OXC) oral suspension in pediatric patients aged 2-5 years with partial seizures (PS) and/or generalized tonic-clonic seizures (GTCS) in real-world clinical practice in China."	7.88	Oxcarbazepine oral suspension in young pediatric patients with partial seizures and/or generalized tonic-clonic seizures in routine clinical practice in China: a prospective observational study. ( Chen, YB; Deng, YC; Fang, F; Hu, XS; Huang, XF; Jiang, L; Lin, ZD; Qin, J; Wang, Y; Wu, Y; Yin, F; Zhang, YQ, 2018)
"This is the first report of mixed respiratory alkalosis and metabolic acidosis in a child treated with sulthiame."	7.76	Respiratory alkalosis and metabolic acidosis in a child treated with sulthiame. ( Garty, BZ; Hoffer, V; Scheuerman, O; Tirosh, I; Weissbach, A, 2010)
"We attributed the acute hyponatremia and seizures to the large increase in dose of carbamazepine in the presence of other risk factors for hyponatremia."	7.73	Carbamazepine-induced hyponatremia: assessment of risk factors. ( Kuz, GM; Manssourian, A, 2005)
"We herein report a case of new-onset epileptic seizures induced by carbamazepine in an individual with autism spectrum disorders (ASD)."	7.72	Carbamazepine may trigger new-onset epileptic seizures in an individual with autism spectrum disorders: a case report. ( Hashioka, S; Maekawa, T; Monji, A; Yanagimoto, K; Yoshida, I, 2004)
"A 64-year-old male with glossopharyngeal neuralgia, cardiac asystole and grand mal seizures has been relieved of his attacks by intake of 400 mg of Carbamazepine per day over a 4-year period."	7.66	Cardiac syncope secondary to glossopharyngeal neuralgia--effectively treated with carbamazepine. ( Nagaswami, S; Yang, CP, 1978)
"Epileptic seizure induction is a rare adverse effect of disulfiram and its aetiological mechanism is unknown."	5.62	Disulfiram-induced epileptic seizures. ( Mendes, MA; Nogueira, V; Pereira, I; Teixeira, J, 2021)
"Practically all children with pure grand mal epilepsy could be kept seizure-free on an optimal dose of phenytoin alone."	5.25	Systematic determination of the serum phenytoin level as an aid in the management of children with epilepsy. ( Gamstorp, I; Lilienberg, G; Norell, E, 1975)
"To review the time to treatment failure, remission and first seizure with carbamazepine compared with phenobarbitone when used as monotherapy in people with focal onset seizures (simple or complex focal and secondarily generalised), or generalised onset tonic-clonic seizures (with or without other generalised seizure types)."	4.98	Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review. ( Marson, AG; Nevitt, SJ; Tudur Smith, C, 2018)
"To review the time to withdrawal, remission, and first seizure of carbamazepine compared with phenobarbitone when used as monotherapy in people with partial onset seizures (simple or complex partial and secondarily generalised) or generalised onset tonic-clonic seizures (with or without other generalised seizure types)."	4.93	Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review. ( Marson, AG; Nolan, SJ; Tudur Smith, C; Weston, J, 2016)
"To review the best evidence comparing phenobarbitone and phenytoin when used as monotherapy in participants with partial onset seizures or generalised tonic-clonic seizures with or without other generalised seizure types."	4.89	Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures. ( Marson, AG; Nolan, SJ; Pulman, J; Tudur Smith, C, 2013)
"To compare the effects of carbamazepine and lamotrigine monotherapy for people with partial onset seizures or generalized onset tonic-clonic seizures."	4.83	A meta-analysis of individual patient responses to lamotrigine or carbamazepine monotherapy. ( Chadwick, DW; Gamble, C; Marson, AG; Williamson, PR, 2006)
"This study aimed to assess efficacy and safety of oxcarbazepine (OXC) oral suspension in pediatric patients aged 2-5 years with partial seizures (PS) and/or generalized tonic-clonic seizures (GTCS) in real-world clinical practice in China."	3.88	Oxcarbazepine oral suspension in young pediatric patients with partial seizures and/or generalized tonic-clonic seizures in routine clinical practice in China: a prospective observational study. ( Chen, YB; Deng, YC; Fang, F; Hu, XS; Huang, XF; Jiang, L; Lin, ZD; Qin, J; Wang, Y; Wu, Y; Yin, F; Zhang, YQ, 2018)
"We report two female infants with early myoclonic encephalopathy (EME) whose intractable focal seizures were suppressed with lidocaine and carbamazepine (CBZ)."	3.79	Successful treatment of early myoclonic encephalopathy using lidocaine and carbamazepine. ( Kobayashi, K; Kodani, N; Maniwa, S; Nakano, K; Ohtsuka, Y, 2013)
"This is the first report of mixed respiratory alkalosis and metabolic acidosis in a child treated with sulthiame."	3.76	Respiratory alkalosis and metabolic acidosis in a child treated with sulthiame. ( Garty, BZ; Hoffer, V; Scheuerman, O; Tirosh, I; Weissbach, A, 2010)
"Using the mouse maximal electroshock-induced seizure model, indicative of tonic-clonic seizures in humans, the present study was aimed at characterizing the interaction between remacemide and valproate, carbamazepine, phenytoin, and phenobarbital."	3.74	Isobolographic analysis of interactions between remacemide and conventional antiepileptic drugs in the mouse model of maximal electroshock. ( Borowicz, KK; Czuczwar, SJ; Luszczki, JJ; Malek, R; Patsalos, PN; Ratnaraj, N, 2007)
"We attributed the acute hyponatremia and seizures to the large increase in dose of carbamazepine in the presence of other risk factors for hyponatremia."	3.73	Carbamazepine-induced hyponatremia: assessment of risk factors. ( Kuz, GM; Manssourian, A, 2005)
"We herein report a case of new-onset epileptic seizures induced by carbamazepine in an individual with autism spectrum disorders (ASD)."	3.72	Carbamazepine may trigger new-onset epileptic seizures in an individual with autism spectrum disorders: a case report. ( Hashioka, S; Maekawa, T; Monji, A; Yanagimoto, K; Yoshida, I, 2004)
"The first patient was a 47-year-old man who developed fever, lymphadenopathy, influenza-like symptoms, facial edema, skin rash and diarrhea after 3 weeks of carbamazepine (CBZ) treatment."	3.70	Colitis may be part of the antiepileptic drug hypersensitivity syndrome. ( Dofferhoff, AS; Eland, IA; Stricker, BH; Vink, R; Zondervan, PE, 1999)
"A 64-year-old male with glossopharyngeal neuralgia, cardiac asystole and grand mal seizures has been relieved of his attacks by intake of 400 mg of Carbamazepine per day over a 4-year period."	3.66	Cardiac syncope secondary to glossopharyngeal neuralgia--effectively treated with carbamazepine. ( Nagaswami, S; Yang, CP, 1978)
"Oxcarbazepine (OXC) has been licensed as monotherapy and add-on treatment in epilepsy patients with partial seizures with or without secondarily generalized seizures (PS) and generalized tonic-clonic seizures without partial onset (GTCS)."	2.68	A double-blind controlled clinical trial: oxcarbazepine versus sodium valproate in adults with newly diagnosed epilepsy. ( Brodie, MJ; Christe, W; Krämer, G; Moore, A; Pohlmann, H; Steinhoff, BJ; Vigonius, U, 1997)
"To determine the rate of recurrence of a second attack after a single unprovoked epileptic seizure by using 2 study groups of treated and untreated patients and, thus, to establish a treatment policy for these patients."	2.68	Early treatment of a single generalized tonic-clonic seizure to prevent recurrence. ( Eshel, Y; Gabbay, U; Gilad, R; Lampl, Y; Sarova-Pinhas, I, 1996)
" Fifty-two children between the age of 2 weeks and 15 years were treated with CBZ (mean dosage 17 mg/kg body weight) either as mono- (n = 36) or in polytherapy (n = 16)."	2.67	The metabolization of carbamazepine to CBZ-10,11-epoxide in children from the newborn age to adolescence. ( Hannak, D; Haug, C; Korinthenberg, R, 1994)
"Carbamazepine was also superior according to a composite score that combined scores for the control of seizures and for adverse effects (P less than 0."	2.67	A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults. The Department of Veterans Affairs Epilepsy Cooperative Study No. 264 Group. ( Collins, JF; Cramer, JA; Mattson, RH, 1992)
" Mean concentration values also differed significantly, which is explained by a somewhat reduced bioavailability (22% less) of the slow-release formulation."	2.67	Diurnal variation of carbamazepine and carbamazepine-10,11-epoxide in plasma and saliva in children with epilepsy: a comparison between conventional and slow-release formulations. ( Arvidsson, J; Eeg-Olofsson, O; Grahn, PA; Gylje, H; Larsson, C; Nilsson, HL; Norén, L; Tonnby, B, 1990)
"Carbamazepine was compared with phenytoin in a double-blind study."	2.65	A double-blind study comparing carbamazepine with phenytoin as initial seizure therapy in adults. ( Berger, JR; Bruni, J; Ramsay, RE; Wilder, BJ, 1983)
"Carbamazepine was found to be an effective anticonvulsant in the treatment of grand mal epilepsy."	2.64	Plasma level and effect of carbamazepine in grand mal and psychomotor epilepsy. ( Christiansen, J; Dam, M; Jensen, A, 1975)
"Lamotrigine was significantly less likely to be withdrawn than carbamazepine but the results for time to first seizure suggested that carbamazepine may be superior in terms of seizure control."	2.53	Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review. ( Marson, AG; Nolan, SJ; Tudur Smith, C; Weston, J, 2016)
"Carbamazepine is a current first-line treatment for partial onset seizures in the USA and Europe."	2.52	Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review. ( Marson, AG; Nolan, SJ; Tudur Smith, C; Weston, J, 2015)
"Carbamazepine (CBZ) is a drug frequently used to treat variety of neurological diseases or symptoms."	2.40	Reversible pitch perception deficit due to carbamazepine. ( Imai, K; Kashihara, K; Shiro, Y; Shohmori, T, 1998)
" The latter must be compensated for by planned dosage increases to maintain therapeutic plasma steady-state levels during the first 2 or 3 months of treatment."	2.37	Carbamazepine efficacy in adults with partial and generalized tonic-clonic seizures. ( Rangel, R; Wilder, BJ, 1987)
"We hypothesized that poor seizure control is associated with new-onset MHC diagnoses and/or new prescription drugs for MHCs."	1.72	Incidence of mental health conditions by seizure control among adults with epilepsy in the United States. ( Ferrari, L; Hauser, WA; Schabert, VF; Stern, S; Wade, CT; Willke, RJ, 2022)
"Epileptic seizure induction is a rare adverse effect of disulfiram and its aetiological mechanism is unknown."	1.62	Disulfiram-induced epileptic seizures. ( Mendes, MA; Nogueira, V; Pereira, I; Teixeira, J, 2021)
"Altogether, 363 patients with new-onset seizures were reviewed in this study."	1.62	Antihistamines as a common cause of new-onset seizures: a single-center observational study. ( Kim, H; Kim, JB; Kim, SH, 2021)
"A woman diagnosed with juvenile myoclonic epilepsy for over 30 years presented with stereotyped episodes of abnormal sensations in both arms."	1.37	Fronto-polar epilepsy masquerading as juvenile myoclonic epilepsy. ( Keezer, MR; Nguyen, DK; Saint-Hilaire, JM, 2011)
"Absence status was aggravated with carbamazepine and generalised tonic-clonic seizures were not controlled with ethosuximide."	1.36	Unilateral continuous subclinical paroxysmal activity: an unusual finding in a patient with recurrent absence status. ( Genton, P; Velizarova, R, 2010)
"Carbamazepine was progressively withdrawn and the patient was progressively switched to zonisamide."	1.35	Wicket spikes misinterpreted as focal abnormalities in idiopathic generalized epilepsy with prescription of carbamazepine leading to paradoxical aggravation. ( Coubes, P; Crespel, A; Gélisse, P; Genton, P; Velizarova, R, 2009)
"Here, we report a typical case of 'senile chorea' associated with PAPS, thus expanding the potential underlying etiologies and further narrowing the window of primary 'senile chorea'."	1.35	Narrowing the window for 'senile chorea': a case with primary antiphospholipid syndrome. ( Apale, P; Appollonio, I; Capra, M; Ferrarese, C; Frigo, M; Galbussera, A; Gelosa, G; Perego, R; Tremolizzo, L, 2009)
"Hashimoto encephalopathy is a chronic relapsing steroid responsive encephalopathy characterized by antibodies against thyroid components."	1.32	[Hashimoto encephalopathy]. ( Günther, P; Kopf, A, 2004)
"Unfortunately, the patient died from adult respiratory distress syndrome."	1.31	Continuous EEG monitoring in a patient with massive carbamazepine overdose. ( De Rubeis, DA; Young, GB, 2001)
"The individualization of carbamazepine (CBZ) dosage regimen based on estimation of pharmacokinetic (PK) parameters and measurement of serum drug concentration in epileptic patients can help to control epilepsy."	1.31	Bayesian estimation of six different sets of carbamazepine pharmacokinetic parameters in Egyptian adult epileptic patients. ( EL Desoky, ES; Kandil, MR, 2002)
"Epilepsy is a relatively common problem in children, adults and the elderly."	1.30	Treatment of the epileptic patient in the dental office. ( Haller, JS; Kennedy, BT, 1998)
"A 11-year-old girl suffering from grand mal epilepsy underwent antiepileptic therapy with carbamazepine (600 mg/daily)."	1.30	[Dose-dependent pellagroid skin reaction caused by carbamazepine]. ( Heyer, G; Schell, H; Simon, M, 1998)
"Between 369 cases of benign partial epilepsy of the childhood with Rolandic spikes (BECRS) diagnosed in our hospital, we have been able to study three patients that have presented a neurophysiological and clinical presentation that was compatible with the form described by Aicardi and Chevrie in 1982."	1.30	[Atypical benign partial epilepsy of childhood. Clinical follow-up EEG study of 3 patients]. ( Bauzano-Poley, E; Delgado-Marqués, MP; Mora-Ramírez, MD; Rodríguez-Barrionuevo, AC; Tosina-García, E, 1998)
" The dosage was increased when she developed generalized tonic-clonic seizures and she is currently maintained on a maximal dose of a controlled release formulation."	1.29	Case summary: Kate. ( Ebbing, A; Kirkham, FJ, 1994)
" We conclude that OPT is a simple yet useful program to derive individual and population pharmacokinetic parameters for CBZ for use in dosage adjustments."	1.29	Estimation of population pharmacokinetics for carbamazepine in Malaysian patients using the OPT computer program. ( Ismail, R; Rahman, AF, 1993)
"Generalized seizures could be evoked in 78% (59/76) of the surviving rats by a 60 s exposure to a loud sound (bell, 110 dB) beginning 24 h after the ischemic episode."	1.29	Audiogenic seizures following global ischemia induced by chest compression in Long-Evans rats. ( Iyer, V; Keelen, P; Miller, J; Payne, RS; Reid, KH; Schurr, A; Tseng, M; Young, C, 1996)
"These seizures were usually precipitated by auditory stimuli such as sudden loud noises."	1.29	Reflex seizures in Down syndrome. ( Louis, S; Pueschel, SM, 1993)
"Valproic acid blood levels were on average 183% of those in maternal blood (n = 15)."	1.28	[The course of pregnancy and teratogenicity of antiepileptic agents in 66 patients with epilepsy]. ( Bülau, P; Fröscher, W; Herrmann, R; Hildenbrand, G; Niesen, M; Penin, H, 1991)
"Only when the epilepsy is uncontrolled despite high plasma concentrations which cannot be raised because of side effects, a second drug should be given."	1.27	[Pharmacotherapy of epilepsy--current problems and controversies]. ( Schmidt, D, 1983)
"Epilepsy is a common disorder affecting approximately one in every two hundred people, from all walks of life, and presenting in addition to the seizure disorder itself, varying social, psychological and economic problems."	1.26	Epilepsy. ( Gilligan, B, 1976)
"Convergence spasm has frequently been reported as a hysterical manifestation."	1.26	Organic convergence spasm. ( Guiloff, RJ; Kelly, RE; Whiteley, A, 1980)
"Carbamazepine (CBZ) was given as the only drug to 62 epileptic patients with mainly simple and complex partial seizures."	1.26	Single-drug therapy with carbamazepine in patients with epilepsy: serum levels and clinical effect. ( Johannessen, SI; Strandjord, RE, 1980)
"Practically all children with pure grand mal epilepsy could be kept seizure-free on an optimal dose of phenytoin alone."	1.25	Systematic determination of the serum phenytoin level as an aid in the management of children with epilepsy. ( Gamstorp, I; Lilienberg, G; Norell, E, 1975)

Research

Studies (171)

Authors

Clinical Trials (1)

Trial Overview

Trial Outcomes

Change From Baseline in Adverse Event Profile (AEP) Score

Timeframe	Studies, this research(%)	All Research%
pre-1990	72 (42.11)	18.7374
1990's	48 (28.07)	18.2507
2000's	27 (15.79)	29.6817
2010's	20 (11.70)	24.3611
2020's	4 (2.34)	2.80

Authors	Studies
Schabert, VF	1
Stern, S	1
Ferrari, L	1
Wade, CT	1
Willke, RJ	1
Hauser, WA	1
Sugitate, R	1
Okubo, Y	1
Nariai, H	1
Matsui, A	1
Kim, H	1
Kim, SH	1
Kim, JB	1
Nogueira, V	1
Mendes, MA	1
Pereira, I	1
Teixeira, J	1
Wang, Y	2
Chen, YB	2
Zhang, YQ	2
Luo, R	1
Wang, H	1
Lv, JL	1
Wang, D	1
Zhu, SQ	1
Lin, ZD	2
Qin, J	2
Kheloufi, F	1
Default, A	1
Perrouty, B	1
Blin, O	1
Micallef, J	1
Huang, XF	1
Fang, F	1
Deng, YC	1
Yin, F	1
Jiang, L	1
Wu, Y	1
Hu, XS	1
Nevitt, SJ	3
Tudur Smith, C	8
Weston, J	4
Marson, AG	9
Sudell, M	2
Nolan, SJ	5
Pulman, J	1
Nakano, K	1
Kobayashi, K	1
Maniwa, S	1
Kodani, N	1
Ohtsuka, Y	1
Gómez, CD	1
Buijs, RM	1
Sitges, M	1
Gelosa, G	1
Tremolizzo, L	1
Galbussera, A	1
Perego, R	1
Capra, M	1
Frigo, M	1
Apale, P	1
Ferrarese, C	1
Appollonio, I	1
Crespel, A	1
Velizarova, R	2
Genton, P	2
Coubes, P	1
Gélisse, P	1
Akula, KK	1
Dhir, A	1
Kulkarni, SK	1
Arhan, E	1
Serdaroglu, A	2
Kurt, AN	1
Aslanyavrusu, M	1
Weissbach, A	1
Tirosh, I	1
Scheuerman, O	1
Hoffer, V	1
Garty, BZ	1
Keezer, MR	1
Saint-Hilaire, JM	1
Nguyen, DK	1
Rajan, DS	1
Popescu, A	1
Nandhagopal, R	1
Akhavan-Sigari, R	1
Rohde, V	1
Abili, M	1
Faught, E	1
Zubcević, S	1
Gavranović, M	1
Katica, V	1
Brajković, D	1
Catibusić, F	1
Cohen, Y	1
Rund, D	1
Moualem, E	1
Kalish, Y	1
Polliack, A	1
TCHICALOFF, M	1
PENNETTI, F	1
JONGMANS, JW	1
HAJNSEK, F	1
SARTORIUS, N	1
Monji, A	1
Maekawa, T	1
Yanagimoto, K	1
Yoshida, I	1
Hashioka, S	1
Günther, P	1
Kopf, A	1
Rainesalo, S	1
Peltola, J	1
Auvinen, A	1
Keränen, T	1
Moraes, MF	1
Chavali, M	1
Mishra, PK	1
Jobe, PC	1
Garcia-Cairasco, N	1
Zdrojewicz, Z	1
Dubiński, A	1
Jonek, A	1
Tomanek, N	1
Krajewski, W	1
Kuz, GM	1
Manssourian, A	1
Zenkov, LR	1
Gamble, C	1
Williamson, PR	1
Chadwick, DW	1
Koussa, S	1
Hage Chahine, S	1
Tohmé, A	1
Riachi, M	1
Paliwal, V	1
Garg, RK	1
Kar, AM	1
Singh, MK	1
Holtschmidt-Täschner, B	1
Soyka, M	1
Borowicz, KK	1
Malek, R	1
Luszczki, JJ	1
Ratnaraj, N	1
Patsalos, PN	1
Czuczwar, SJ	3
Cansu, A	1
Giray, SG	1
Erdogan, D	1
Coskun, ZK	1
Korucuoglu, U	1
Biri, AA	1
Ramsay, RE	1
Wilder, BJ	2
Berger, JR	1
Bruni, J	1
Andersen, EB	1
Philbert, A	1
Klee, JG	1
Schmidt, D	1
Rapport, MD	1
Sonis, WA	1
Fialkov, MJ	1
Matson, JL	1
Kazdin, AE	1
Forsythe, WI	4
Sills, MA	1
Guiloff, RJ	1
Whiteley, A	1
Kelly, RE	1
Massey, EW	1
Strandjord, RE	1
Johannessen, SI	1
Reynolds, EH	2
Shorvon, SD	1
Owens, JR	1
Toothill, C	2
Eichelbaum, M	2
Köthe, KW	1
Hoffmann, F	1
von Unruh, GE	1
Lundström, A	1
Eeg-Olofsson, O	3
Hamp, SE	1
Fröscher, W	3
Hildenbrand, G	2
Hildenbrand, K	1
Penin, H	2
Marciani, MG	1
Maschio, M	1
Spanedda, F	1
Iani, C	1
Gigli, GL	1
Bernardi, G	1
Silvestri, R	1
de Domenico, P	1
Mento, G	1
Laganà, A	1
di Perri, R	1
Korinthenberg, R	1
Haug, C	1
Hannak, D	1
Kirkham, FJ	1
Ebbing, A	1
Motohashi, N	1
Kubota, M	1
Onose, H	1
Kariya, T	1
Froomes, PR	1
Stewart, MR	1
De Deyn, PP	1
Mol, L	1
de Ridder-Vanderdeelen, P	1
Eerdekens, M	1
Seino, M	1
Chadwick, D	1
Sälke-Kellermann, A	1
Baier, H	1
Rambeck, B	1
Boenigk, HE	1
Wolf, P	2
Knott, C	1
Panayiotopoulos, CP	1
Specht, U	1
Rohde, M	1
May, T	1
Schmidt, RC	1
Meencke, HJ	1
Mares, P	1
Seidl, J	1
Nováková, J	1
Kouji, T	1
Kohyama, J	1
Shimohira, M	1
Iwakawa, Y	1
Araki, S	1
Wakimoto, H	1
Tsuchiya, S	1
Spina, E	1
Avenoso, A	1
Pollicino, AM	1
Caputi, AP	1
Fazio, A	1
Pisani, F	1
Ruiz-Falcó Rojas, ML	1
Gutiérrez-Solana, LG	1
Arias Alvarez, MA	1
Barrio Nicolás, A	1
López-Terradas Covisa, JM	1
Riley, RJ	1
Smith, G	1
Wolf, CR	1
Cook, VA	1
Leeder, JS	1
Ismail, R	1
Rahman, AF	1
Pueschel, SM	1
Louis, S	2
de Silva, M	1
MacArdle, B	1
McGowan, M	1
Hughes, E	1
Stewart, J	1
Neville, BG	1
Johnson, AL	1
Reid, KH	1
Young, C	1
Schurr, A	1
Tseng, M	1
Payne, RS	1
Keelen, P	1
Miller, J	1
Iyer, V	1
Tomlinson, B	1
Young, RP	1
Ng, MC	1
Anderson, PJ	1
Kay, R	1
Critchley, JA	1
Gilad, R	1
Lampl, Y	1
Gabbay, U	1
Eshel, Y	1
Sarova-Pinhas, I	1
Gasior, M	1
Kozicka, M	1
Pietrasiewicz, T	1
Turski, WA	2
Kleinrok, Z	2
Christe, W	1
Krämer, G	1
Vigonius, U	1
Pohlmann, H	1
Steinhoff, BJ	1
Brodie, MJ	1
Moore, A	1
Windhaber, J	1
Maierhofer, D	1
Dantendorfer, K	1
del Brutto, OH	1
Kennedy, BT	1
Haller, JS	1
Heyer, G	1
Simon, M	1
Schell, H	1
Rodríguez-Barrionuevo, AC	1
Bauzano-Poley, E	1
Delgado-Marqués, MP	1
Mora-Ramírez, MD	1
Tosina-García, E	1
Shakespeare, A	1
Simeon, G	1
Arita, K	1
Kurisu, K	1
Iida, K	1
Hanaya, R	1
Akimitsu, T	1
Hibino, S	1
Pant, B	1
Hamasaki, M	1
Shinagawa, S	1
Kashihara, K	1
Imai, K	1
Shiro, Y	1
Shohmori, T	1
Cocito, L	1
Primavera, A	1
Brown, KL	1
Henderson, DC	1
Nadel, S	1
Tanveer, A	1
Booy, R	1
Go, T	1
Singhi, P	1
Ray, M	1
Urbanska, EM	1
Tomczyk, T	1
Haberek, G	1
Pilip, S	1
Matyska, J	1
Eland, IA	1
Dofferhoff, AS	1
Vink, R	1
Zondervan, PE	1
Stricker, BH	1
Bauer, J	1
Saher, MS	1
Burr, W	1
Elger, CE	1
Smith, PE	1
De Rubeis, DA	1
Young, GB	1
French, JA	1
Yüksel, A	1
Cengiz, M	1
Seven, M	1
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Trial	Phase	Enrollment	Study Type	Start Date	Status
An Open Prospective Randomised Long-Term Effectiveness Study, Comparing Best Medical Practice With or Without Adjunctive VNS Therapy in Patients 16 Years and Older With Pharmaco-resistant Partial Epilepsy[NCT00522418]	Phase 4	122 participants (Actual)	Interventional	2006-02-28	Terminated (stopped due to Insufficient enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Adverse Events Profile (AEP) is a 19-item scale used as a systematic measure of adverse effects from antiepileptic drugs (AEDs). Scores range from 19-76; higher scores indicate high prevelance and severity of adverse events. (NCT00522418)
Timeframe: Mean change from baseline AEP Score at 12 months

Change From Baseline in Center for Epidemiologic Studies Depression Scale (CES-D) Score

Intervention	Units on a scale (Mean)
VNS Therapy	-6.0
Best Medical Practice	-3.2

The Center for Epidemiologic Studies Depression Scale (CES-D) includes 20 items comprising six scales reflecting major dimensions of depression: depressed mood, feelings of guilt and worthlessness, feelings of helplessness and hopelessness, psychomotor retardation, loss of appetite, and sleep disturbance. Possible range of scores is 0 to 60, higher scores indicate more depressive symptoms. (NCT00522418)
Timeframe: Mean change from baseline CES-D Score at 12 months

Change From Baseline in Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) Score

Intervention	Units on a Scale (Mean)
VNS Therapy	-2.2
Best Medical Practice	0.5

The Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) is a 6-item questionnaire validated to screen for depression in people with epilepsy. Scores range from 6 to 24, with higher scores indicating more depressive symptoms. (NCT00522418)
Timeframe: Mean change from baseline NDDI-E Score at 12 months

Changes in Anti-epileptic Drugs (AEDs)

Intervention	Units on a Scale (Mean)
VNS Therapy	-1.0
Best Medical Practice	-0.2

Change from baseline in number of AED medications by visit (NCT00522418)
Timeframe: Change from baseline in number of AEDs at 12 months

Mean Change From Beginning of Intervention Clinical Global Impression-Improvement Scale (CGI-I) Score at 12 Months

Intervention	Number of AEDs Taken (Median)
VNS Therapy	0
Best Medical Practice	0

The Clinical Global Impression scale (CGI-I) is a 7 point scale that requires the clinician to assess how much the patient's illness has improved or worsened relative to a baseline state at the beginning of the intervention Scores range from 1-7: 1, very much improved; 2, much improved; 3, minimally improved; 4, no change; 5, minimally worse; 6, much worse; or 7, very much worse. (NCT00522418)
Timeframe: Mean change from baseline CGI-I Score at 12 months

Mean Percent Change in Seizure Frequency

Intervention	Units on a Scale (Mean)
VNS Therapy	-0.8
Best Medical Practice	-0.3

Percent change in total seizuires per week from baseline at 12 months (NCT00522418)
Timeframe: Mean percent change from baseline in seizure frequency at 12 months

Overall Quality of Life in Epilepsy-89 (QOLIE-89) Score in Patients With Baseline & at Least One Post-baseline QOLIE Assessment

Intervention	Percent Change (Mean)
VNS Therapy	-19.1
Best Medical Practice	-1.0

QOLIE-89 contains 17 multi-item measures of overall quality of life, emotional well-being, role limitations due to emotional problems, social support, social isolation, energy/fatigue, worry about seizure, medication effects, health discouragement, work/driving/social function, attention/concentration, language, memory, physical function, pain, role limitations due to physical problems, and health perceptions. Range of values 0-100. Higher scores reflect better quality of life; lower ones, worse quality of life. (NCT00522418)
Timeframe: Mean change from baseline QOLIE-89 Overall Score at 12 months

Response Rate

Intervention	units on a scale (Mean)
VNS Therapy	5.5
Best Medical Practice	1.2

Response Rate is defined as the percent of participants who are responders. A Responder is defined as participants with a reduction of at least 50% or 75% in seizure frequency from baseline to the seizure count evaluation period. (NCT00522418)
Timeframe: Number of Responders at 12 Months

Change From Baseline in QOLIE-89 Measures: Subgroup Analysis of Population With Baseline Adverse Event Profile Score < 40

Intervention	participants (Number)
VNS Therapy	10
Best Medical Practice	7

QOLIE-89 contains 17 multi-item measures of overall quality of life. Range of values 0-100. Higher scores reflect better quality of life; lower ones, worse quality of life. Adverse Events Profile (AEP) is a 19-item scale used as a systematic measure of adverse effects from antiepileptic drugs (AEDs). Scores range from 19-76; higher scores indicate high prevelance and severity of adverse events. (NCT00522418)
Timeframe: Change from baseline up to 12 months

Change From Baseline in QOLIE-89 Measures: Subgroup Analysis of Population With Baseline Adverse Event Profile Score >= 40

Article	Year
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Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review. The Cochrane database of systematic reviews, 2018, 06-28, Volume: 6 Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy,	2018
Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review. The Cochrane database of systematic reviews, 2018, 10-24, Volume: 10 Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy,	2018
Topiramate versus carbamazepine monotherapy for epilepsy: an individual participant data review. The Cochrane database of systematic reviews, 2019, 06-24, Volume: 6 Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epi	2019
Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures. The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1 Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; I	2013
Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review. The Cochrane database of systematic reviews, 2015, Jul-23, Issue:7 Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy,	2015
Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review. The Cochrane database of systematic reviews, 2016, 11-14, Volume: 11 Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy,	2016
Topiramate versus carbamazepine monotherapy for epilepsy: an individual participant data review. The Cochrane database of systematic reviews, 2016, 12-06, Volume: 12 Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic;	2016
Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review. The Cochrane database of systematic reviews, 2016, 12-15, Volume: 12 Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy,	2016
A meta-analysis of individual patient responses to lamotrigine or carbamazepine monotherapy. Neurology, 2006, May-09, Volume: 66, Issue:9 Topics: Adult; Anticonvulsants; Carbamazepine; Child; Disease-Free Survival; Double-Blind Method; Epilepsies	2006
A comment on the efficacy of valproate in the treatment of partial seizures. Epilepsia, 1994, Volume: 35 Suppl 5 Topics: Carbamazepine; Clinical Trials as Topic; Drugs, Investigational; Epilepsies, Partial; Epilepsy, Toni	1994
Valproate in the treatment of partial epilepsies. Epilepsia, 1994, Volume: 35 Suppl 5 Topics: Adolescent; Adult; Carbamazepine; Child; Double-Blind Method; Drug Therapy, Combination; Epilepsies,	1994
Reversible pitch perception deficit due to carbamazepine. Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:9 Topics: Adolescent; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Female; Hea	1998
The role of new antiepileptic drugs. The American journal of managed care, 2001, Volume: 7, Issue:7 Suppl Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsies, Partial; Epilepsy; Epi	2001
Carbamazepine efficacy and utilization in children. Epilepsia, 1987, Volume: 28 Suppl 3 Topics: Carbamazepine; Child; Drug Interactions; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, A	1987
Carbamazepine efficacy in adults with partial and generalized tonic-clonic seizures. Epilepsia, 1987, Volume: 28 Suppl 3 Topics: Adult; Carbamazepine; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Phenytoin	1987
[Course and prognosis of infantile epilepsy in relation to present-day treatment]. La Pediatria, 1970, Dec-31, Volume: 78, Issue:6 Topics: Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Brain Diseases; Carbamazepine; Central Ner	1970
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Oxcarbazepine oral suspension in pediatric patients with partial seizures and/or generalized tonic-clonic seizures: a multi-center, single arm, observational study in China. World journal of pediatrics : WJP, 2017, Volume: 13, Issue:6 Topics: Administration, Oral; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Admi	2017
A double-blind study comparing carbamazepine with phenytoin as initial seizure therapy in adults. Neurology, 1983, Volume: 33, Issue:7 Topics: Adolescent; Adult; Aged; Carbamazepine; Double-Blind Method; Epilepsies, Partial; Epilepsy, Tonic-Cl	1983
[Prospective studies on epilepsy therapy with carbamazepine]. Fortschritte der Neurologie-Psychiatrie, 1982, Volume: 50, Issue:12 Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clinical Trials as Topic; Epilepsies, Myoclonic; Epil	1982
The metabolization of carbamazepine to CBZ-10,11-epoxide in children from the newborn age to adolescence. Neuropediatrics, 1994, Volume: 25, Issue:4 Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Child Development; Child, Preschool;	1994
Carbamazepine coadministration with fluoxetine or fluvoxamine. Therapeutic drug monitoring, 1993, Volume: 15, Issue:3 Topics: Adult; Carbamazepine; Depression; Drug Interactions; Drug Therapy, Combination; Epilepsy, Complex Pa	1993
Randomised comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed childhood epilepsy. Lancet (London, England), 1996, Mar-16, Volume: 347, Issue:9003 Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy;	1996
Early treatment of a single generalized tonic-clonic seizure to prevent recurrence. Archives of neurology, 1996, Volume: 53, Issue:11 Topics: Adult; Carbamazepine; Epilepsy, Tonic-Clonic; Female; Humans; Male; Prognosis; Recurrence; Time Fact	1996
A double-blind controlled clinical trial: oxcarbazepine versus sodium valproate in adults with newly diagnosed epilepsy. Epilepsy research, 1997, Volume: 26, Issue:3 Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Double-Bl	1997
Economic analysis of epilepsy treatment: a cost minimization analysis comparing carbamazepine and lamotrigine in the UK. Seizure, 1998, Volume: 7, Issue:2 Topics: Anticonvulsants; Carbamazepine; Cost Control; Decision Support Techniques; Drug Costs; Epilepsies, P	1998
[Carbamazepine (Tegretol) or phenytoin in the treatment of focal motor epilepsy or generalized epilepsy? A controlled clinical trial]. Ugeskrift for laeger, 1979, Apr-09, Volume: 141, Issue:15 Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Evaluati	1979
Carbamazepine in difficult to control epileptic out-patients. Acta neurologica Scandinavica. Supplementum, 1975, Volume: 60 Topics: Adolescent; Adult; Ambulatory Care; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic	1975
Plasma level and effect of carbamazepine in grand mal and psychomotor epilepsy. Acta neurologica Scandinavica. Supplementum, 1975, Volume: 60 Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clinical Trials as Topic; Drug Evaluation; Drug Thera	1975
A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults. The Department of Veterans Affairs Epilepsy Cooperative Study No. 264 Group. The New England journal of medicine, 1992, Sep-10, Volume: 327, Issue:11 Topics: Adolescent; Adult; Aged; Carbamazepine; Double-Blind Method; Epilepsy, Complex Partial; Epilepsy, To	1992
Diurnal variation of carbamazepine and carbamazepine-10,11-epoxide in plasma and saliva in children with epilepsy: a comparison between conventional and slow-release formulations. Journal of child neurology, 1990, Volume: 5, Issue:2 Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Circadian Rhythm; Delayed-Action Preparations; E	1990
Breakthrough seizures with generic carbamazepine? Developmental medicine and child neurology, 1990, Volume: 32, Issue:5 Topics: Adolescent; Carbamazepine; Child; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-C	1990
Carbamazepine for epilepsy. A controlled prospective evaluation. Neurology, 1974, Volume: 24, Issue:5 Topics: Adult; Blood Cell Count; Bone Marrow Diseases; Carbamazepine; Clinical Trials as Topic; Electroencep	1974
The effects of carbamazepine on patients with psychomotor epilepsy: results of a double-blind study. Epilepsia, 1974, Volume: 15, Issue:4 Topics: Adolescent; Adult; Analysis of Variance; Behavior; Carbamazepine; Cerebral Cortex; Clinical Trials a	1974

Article	Year
Incidence of mental health conditions by seizure control among adults with epilepsy in the United States. Epilepsy & behavior : E&B, 2022, Volume: 134 Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Epilepsy, Ge	2022
Antihistamines as a common cause of new-onset seizures: a single-center observational study. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021, Volume: 42, Issue:6 Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic;	2021
Disulfiram-induced epileptic seizures. BMJ case reports, 2021, Mar-17, Volume: 14, Issue:3 Topics: Anticonvulsants; Carbamazepine; Disulfiram; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, To	2021
Perampanel-associated self-harm ideation after dosage increase. European journal of clinical pharmacology, 2018, Volume: 74, Issue:2 Topics: Adult; Anticonvulsants; Carbamazepine; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsie	2018
Oxcarbazepine oral suspension in young pediatric patients with partial seizures and/or generalized tonic-clonic seizures in routine clinical practice in China: a prospective observational study. World journal of pediatrics : WJP, 2018, Volume: 14, Issue:3 Topics: Administration, Oral; Age Factors; Anticonvulsants; Carbamazepine; Child, Preschool; China; Dose-Res	2018
Successful treatment of early myoclonic encephalopathy using lidocaine and carbamazepine. Epileptic disorders : international epilepsy journal with videotape, 2013, Volume: 15, Issue:3 Topics: Anesthetics, Local; Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Epilepsy, Tonic-C	2013
The anti-seizure drugs vinpocetine and carbamazepine, but not valproic acid, reduce inflammatory IL-1β and TNF-α expression in rat hippocampus. Journal of neurochemistry, 2014, Volume: 130, Issue:6 Topics: 4-Aminopyridine; Animals; Anticonvulsants; Behavior, Animal; Blotting, Western; Carbamazepine; Convu	2014
Narrowing the window for 'senile chorea': a case with primary antiphospholipid syndrome. Journal of the neurological sciences, 2009, Sep-15, Volume: 284, Issue:1-2 Topics: Age of Onset; Aged; Anti-Dyskinesia Agents; Antibodies, Antiphospholipid; Anticonvulsants; Antiphosp	2009
Wicket spikes misinterpreted as focal abnormalities in idiopathic generalized epilepsy with prescription of carbamazepine leading to paradoxical aggravation. Neurophysiologie clinique = Clinical neurophysiology, 2009, Volume: 39, Issue:3 Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Clonazepam; Diagnostic Errors; Drug Thera	2009
Effect of various antiepileptic drugs in a pentylenetetrazol-induced seizure model in mice. Methods and findings in experimental and clinical pharmacology, 2009, Volume: 31, Issue:7 Topics: Adenosine; Algorithms; Animals; Anti-Inflammatory Agents; Anticonvulsants; Barbiturates; Carbamazepi	2009
Drug treatment failures and effectivity in children with newly diagnosed epilepsy. Seizure, 2010, Volume: 19, Issue:9 Topics: Adolescent; Age of Onset; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child; Child, Pre	2010
Respiratory alkalosis and metabolic acidosis in a child treated with sulthiame. Pediatric emergency care, 2010, Volume: 26, Issue:10 Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Anticonvulsants; Carbamazepine; Child; Confusion; Dose-R	2010
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Corpus callosum lipoma. Neurology, 2012, Apr-24, Volume: 78, Issue:17 Topics: Agenesis of Corpus Callosum; Anticonvulsants; Brain Neoplasms; Carbamazepine; Corpus Callosum; Epile	2012
Seizure and skin lesions. Neurosciences (Riyadh, Saudi Arabia), 2013, Volume: 18, Issue:1 Topics: Anticonvulsants; Carbamazepine; Epilepsy, Tonic-Clonic; Humans; Magnetic Resonance Imaging; Male; Sk	2013
Stevens Johnson syndrome--an adverse drug reaction occurred after uncomplicated removal of an intracerebral cavernous hemangioma. Journal of neurological surgery. Part A, Central European neurosurgery, 2013, Volume: 74 Suppl 1 Topics: Adolescent; Anticonvulsants; Brain Neoplasms; Carbamazepine; Drug Eruptions; Epilepsies, Partial; Ep	2013
A steelworker with infrequent seizures. Epilepsy & behavior : E&B, 2003, Volume: 4 Suppl 1 Topics: Anticonvulsants; Carbamazepine; Epilepsy, Tonic-Clonic; Humans; Male; Occupations	2003
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[Pharmacotherapy of epilepsy--current problems and controversies]. Fortschritte der Neurologie-Psychiatrie, 1983, Volume: 51, Issue:11 Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy,	1983
Carbamazepine and behavior therapy for aggressive behavior. Treatment of a mentally retarded, postencephalitic adolescent with seizure disorder. Behavior modification, 1983, Volume: 7, Issue:2 Topics: Adolescent; Aggression; Behavior Therapy; Carbamazepine; Combined Modality Therapy; Encephalitis; Ep	1983
One drug for childhood grand mal: medical audit for three-year remissions. Developmental medicine and child neurology, 1984, Volume: 26, Issue:6 Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Epilepsy, Tonic-Clo	1984
Organic convergence spasm. Acta neurologica Scandinavica, 1980, Volume: 61, Issue:4 Topics: Adolescent; Alpha Rhythm; Brain; Carbamazepine; Dose-Response Relationship, Drug; Electroencephalogr	1980
Drug error in anticonvulsant therapy. Annals of neurology, 1980, Volume: 8, Issue:4 Topics: Adult; Carbamazepine; Epilepsy, Tonic-Clonic; Female; Humans; Medication Errors	1980
Single-drug therapy with carbamazepine in patients with epilepsy: serum levels and clinical effect. Epilepsia, 1980, Volume: 21, Issue:6 Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Temporal Lobe; Epileps	1980
Monotherapy or polytherapy for epilepsy? Epilepsia, 1981, Volume: 22, Issue:1 Topics: Adolescent; Adult; Carbamazepine; Clonazepam; Drug Combinations; Drug Interactions; Drug Therapy, Co	1981
Effectiveness of acetazolamide in the treatment of carbamazepine-resistant epilepsy in children. Developmental medicine and child neurology, 1981, Volume: 23, Issue:6 Topics: Acetazolamide; Adolescent; Carbamazepine; Child; Child, Preschool; Drug Resistance; Drug Therapy, Co	1981
Use of stable labelled carbamazepine to study its kinetics during chronic carbamazepine treatment. European journal of clinical pharmacology, 1982, Volume: 23, Issue:3 Topics: Administration, Oral; Adult; Carbamazepine; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female;	1982
Effects of anti-epileptic drug treatment with carbamazepine or phenytoin on the oral state of children and adolescents. Journal of clinical periodontology, 1982, Volume: 9, Issue:6 Topics: Adolescent; Adult; Carbamazepine; Child; Dental Plaque; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clo	1982
Development of myoclonus in patients with partial epilepsy during treatment with vigabatrin: an electroencephalographic study. Acta neurologica Scandinavica, 1995, Volume: 91, Issue:1 Topics: Adolescent; Adult; Aged; Anticonvulsants; Brain; Carbamazepine; Delta Rhythm; Electroencephalography	1995
Epileptic seizures in subjects previously affected by disorders of arousal. Neurophysiologie clinique = Clinical neurophysiology, 1995, Volume: 25, Issue:1 Topics: Adolescent; Adult; Arousal; Carbamazepine; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; Female	1995
Case summary: Kate. Seizure, 1994, Volume: 3 Suppl A Topics: Adrenocorticotropic Hormone; Anticonvulsants; Brain Neoplasms; Carbamazepine; Child; Child, Preschoo	1994
Is there any relationship between anticonvulsant and mood-stabilizing effects of carbamazepine? Pharmacopsychiatry, 1994, Volume: 27, Issue:4 Topics: Affect; Anticonvulsants; Carbamazepine; Depressive Disorder; Epilepsy, Tonic-Clonic; Female; Humans;	1994
A reversible parkinsonian syndrome and hepatotoxcity following addition of carbamazepine to sodium valproate. Australian and New Zealand journal of medicine, 1994, Volume: 24, Issue:4 Topics: Aged; Carbamazepine; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Interactions; Drug Th	1994
An open multicentre prospective study of the effects of monotherapy with controlled-release carbamazepine on newly diagnosed generalized tonic-clonic seizures. Seizure, 1994, Volume: 3, Issue:3 Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Child, Preschool; Delayed-Action Preparations; Epilep	1994
Acute encephalopathy with vigabatrin. Lancet (London, England), 1993, Jul-17, Volume: 342, Issue:8864 Topics: 4-Aminobutyrate Transaminase; Adolescent; Adult; Aminocaproates; Anticonvulsants; Carbamazepine; Com	1993
Carbamazepine in the treatment of generalised tonic clonic seizures in juvenile myoclonic epilepsy. Journal of neurology, neurosurgery, and psychiatry, 1994, Volume: 57, Issue:4 Topics: Adult; Carbamazepine; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Female; Humans	1994
Cerebellar atrophy does not increase susceptibility to carbamazepine toxicity. Acta neurologica Scandinavica, 1994, Volume: 89, Issue:1 Topics: Adolescent; Adult; Atrophy; Carbamazepine; Cerebellar Ataxia; Cerebellum; Dose-Response Relationship	1994
Differential action of phenytoin and carbamazepine on cortical interhemispheric responses in young but not in adult rats. Neuroscience letters, 1993, Sep-17, Volume: 160, Issue:1 Topics: Aging; Analysis of Variance; Animals; Carbamazepine; Electric Stimulation; Epilepsy, Tonic-Clonic; M	1993
Polysomnographical study in the patients of frontal lobe epilepsy with ictal automatism. The Japanese journal of psychiatry and neurology, 1993, Volume: 47, Issue:2 Topics: Automatism; Basal Ganglia; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy, Frontal Lobe;	1993
[Lafora disease. Report of a new case diagnosed by biopsy from the axillary skin]. Anales espanoles de pediatria, 1993, Volume: 38, Issue:3 Topics: Axilla; Biopsy; Carbamazepine; Child; Eccrine Glands; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic;	1993
Human anti-endoplasmic reticulum autoantibodies produced in aromatic anticonvulsant hypersensitivity reactions recognise rodent CYP3A proteins and a similarly regulated human P450 enzyme(s) Biochemical and biophysical research communications, 1993, Feb-26, Volume: 191, Issue:1 Topics: Adult; Animals; Anticonvulsants; Autoantibodies; Autoantigens; Carbamazepine; Cell Line; Cross React	1993
Estimation of population pharmacokinetics for carbamazepine in Malaysian patients using the OPT computer program. Journal of clinical pharmacy and therapeutics, 1993, Volume: 18, Issue:1 Topics: Adolescent; Adult; Carbamazepine; Child; Epilepsy, Tonic-Clonic; Female; Half-Life; Humans; Malaysia	1993
Reflex seizures in Down syndrome. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1993, Volume: 9, Issue:1 Topics: Acoustic Stimulation; Adult; Carbamazepine; Cerebral Cortex; Down Syndrome; Electroencephalography;	1993
Audiogenic seizures following global ischemia induced by chest compression in Long-Evans rats. Epilepsy research, 1996, Volume: 23, Issue:3 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Behavior, Animal; Biomechanical Phenomena; Blood Glu	1996
Selective liver enzyme induction by carbamazepine and phenytoin in Chinese epileptics. European journal of clinical pharmacology, 1996, Volume: 50, Issue:5 Topics: Acetaminophen; Adult; Anticonvulsants; Carbamazepine; China; Cytochrome P-450 Enzyme System; Enzyme	1996
Influence of a potential anti-asthmatic drug, CR 2039, upon the anticonvulsive activity of conventional antiepileptics against maximal electroshock-induced seizures in mice. Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:12 Topics: Animals; Anticonvulsants; Asthma; Avoidance Learning; Benzamides; Bronchodilator Agents; Carbamazepi	1996
Oxcarbazepine for panic disorder occurring after two grand mal seizures: a case report. The Journal of clinical psychiatry, 1997, Volume: 58, Issue:9 Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy, Tonic-Clonic; Humans; Male; Oxcarbazepine; Panic Di	1997
[Neurocysticercosis in children: clinical and radiological analysis and prognostic factors in 54 patients]. Revista de neurologia, 1997, Volume: 25, Issue:147 Topics: Adolescent; Albendazole; Anthelmintics; Anticonvulsants; Brain; Brain Diseases; Carbamazepine; Child	1997
Treatment of the epileptic patient in the dental office. The New York state dental journal, 1998, Volume: 64, Issue:2 Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dental Care for Chronically Ill; Emergencies; Ep	1998
[Dose-dependent pellagroid skin reaction caused by carbamazepine]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1998, Volume: 49, Issue:2 Topics: Anticonvulsants; Biopsy; Carbamazepine; Child; Diagnosis, Differential; Drug Eruptions; Epilepsy, To	1998
[Atypical benign partial epilepsy of childhood. Clinical follow-up EEG study of 3 patients]. Revista de neurologia, 1998, Volume: 26, Issue:150 Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Electroencephalography; Epilepsies, Pa	1998
Subsidence of seizure induced by stereotactic radiation in a patient with hypothalamic hamartoma. Case report. Journal of neurosurgery, 1998, Volume: 89, Issue:4 Topics: Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, To	1998
Vigabatrin aggravates absences and absence status. Neurology, 1998, Volume: 51, Issue:5 Topics: Adult; Anticonvulsants; Asphyxia; Brain Damage, Chronic; Carbamazepine; Drug Therapy, Combination; E	1998
Carbamazepine hypersensitivity and the use of lymphocyte proliferation responses. Developmental medicine and child neurology, 1999, Volume: 41, Issue:4 Topics: Anticonvulsants; Carbamazepine; Cell Division; Child, Preschool; Drug Hypersensitivity; Epilepsy, To	1999
[Carbamazepine-induced involuntary movements in a girl with localization-related epilepsy]. No to hattatsu = Brain and development, 1999, Volume: 31, Issue:4 Topics: Anticonvulsants; Carbamazepine; Child; Dyskinesia, Drug-Induced; Epilepsies, Partial; Epilepsy, Toni	1999
Focal seizures with single small ring-enhancing lesion. Seminars in pediatric neurology, 1999, Volume: 6, Issue:3 Topics: Acute Disease; Albendazole; Anthelmintics; Anticonvulsants; Brain Edema; Carbamazepine; Diagnosis, D	1999
NMDA- but not kainate-mediated events reduce efficacy of some antiepileptic drugs against generalized tonic-clonic seizures in mice. Epilepsia, 1999, Volume: 40, Issue:11 Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationshi	1999
Colitis may be part of the antiepileptic drug hypersensitivity syndrome. Epilepsia, 1999, Volume: 40, Issue:12 Topics: Adult; Anticonvulsants; Carbamazepine; Colitis; Drug Hypersensitivity; Epilepsies, Partial; Epilepsy	1999
Precipitating factors and therapeutic outcome in epilepsy with generalized tonic-clonic seizures. Acta neurologica Scandinavica, 2000, Volume: 102, Issue:4 Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Convulsants; Electroencephalography; Epil	2000
Clinical recommendations for oxcarbazepine. Seizure, 2001, Volume: 10, Issue:2 Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Drug Administration Schedule; Epilepsy, To	2001
Continuous EEG monitoring in a patient with massive carbamazepine overdose. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2001, Volume: 18, Issue:2 Topics: Adult; Brain; Carbamazepine; Coma; Drug Overdose; Electroencephalography; Epilepsy, Tonic-Clonic; Fa	2001
Changes in the antioxidant system in epileptic children receiving antiepileptic drugs: two-year prospective studies. Journal of child neurology, 2001, Volume: 16, Issue:8 Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Epilepsy, Tonic-Clonic; Female; Glutathione; Glu	2001
Carbamazepine induced right bundle branch block in a Greenlandic patient. International journal of circumpolar health, 2001, Volume: 60, Issue:3 Topics: Anticonvulsants; Bundle-Branch Block; Carbamazepine; Dose-Response Relationship, Drug; Electrocardio	2001
Bayesian estimation of six different sets of carbamazepine pharmacokinetic parameters in Egyptian adult epileptic patients. Pharmacological research, 2002, Volume: 45, Issue:2 Topics: Adolescent; Adult; Anticonvulsants; Bayes Theorem; Body Weight; Carbamazepine; Egypt; Epilepsy, Toni	2002
Loss prevention case of the month. Knowledge deficit: all of us have them. Tennessee medicine : journal of the Tennessee Medical Association, 2002, Volume: 95, Issue:5 Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy, Tonic-Clonic; Fatal Outcome; Female; Humans; Malpra	2002
Epilepsy. Australian family physician, 1976, Volume: 5, Issue:7 Topics: Automobile Driving; Barbiturates; Benzodiazepines; Carbamazepine; Diagnosis, Differential; Epilepsie	1976
[The coincidence of visceral lupus erythematosus and epilepsy]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1978, Sep-15, Volume: 33, Issue:18 Topics: Adolescent; Carbamazepine; Epilepsy, Tonic-Clonic; Humans; Lupus Erythematosus, Systemic; Male; Phen	1978
Cardiac syncope secondary to glossopharyngeal neuralgia--effectively treated with carbamazepine. The Journal of clinical psychiatry, 1978, Volume: 39, Issue:10 Topics: Arrhythmias, Cardiac; Brain; Carbamazepine; Epilepsy, Tonic-Clonic; Follow-Up Studies; Glossopharyng	1978
[Blood level of antiepileptic drugs and therapeutic effect in mono- and polytherapy (author's transl)]. Der Nervenarzt, 1978, Volume: 49, Issue:11 Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Comb	1978
Carbamazepine in childhood seizures. Developmental medicine and child neurology, 1978, Volume: 20, Issue:5 Topics: Barbiturates; Carbamazepine; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Phenytoin; Sei	1978
[Time-dependency of serum carbamazepine concentration (author's transl)]. No to shinkei = Brain and nerve, 1978, Volume: 30, Issue:12 Topics: Adolescent; Adult; Age Factors; Aged; Carbamazepine; Child; Epilepsy; Epilepsy, Tonic-Clonic; Female	1978
Carbamazepine serum levels in children with epilepsy: a micro immuno-assay technique. Developmental medicine and child neurology, 1979, Volume: 21, Issue:4 Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy, Temp	1979
[Psychotropic drugs in the clinical picture of epilepsy (review of the literature)]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:3 Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Carbamazepine; C	1975
Systematic determination of the serum phenytoin level as an aid in the management of children with epilepsy. European neurology, 1975, Volume: 13, Issue:3 Topics: Acetazolamide; Adolescent; Carbamazepine; Child; Child, Preschool; Contraceptives, Oral; Drug Intera	1975
[Findings concerning psychopathology, psychometry and serum concentration during high dosage ambulant treatment with carbamazepine (Tegretal) in complicated epilepsy]. Bibliotheca psychiatrica, 1975, Issue:151 Topics: Adult; Carbamazepine; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle	1975
Carbamazepine in the management of seizure disorders. The Medical letter on drugs and therapeutics, 1975, Aug-29, Volume: 17, Issue:18 Topics: Anticonvulsants; Carbamazepine; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans	1975
Sensible prescribing. XI.--Juvenile and adult epilepsy. The Practitioner, 1975, Volume: 215, Issue:1289 Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Clonazepam; Epilepsy; Epilepsy, Absence; Epile	1975
A comparison of the effectiveness of primidone versus carbamazepine in epileptic outpatients. The Journal of nervous and mental disease, 1976, Volume: 163, Issue:1 Topics: Adolescent; Adult; Carbamazepine; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; M	1976
Clinical picture and long-term course of epileptic seizures that occur during clozapine treatment. Psychiatry research, 1992, Volume: 44, Issue:2 Topics: Adult; Carbamazepine; Clonazepam; Clozapine; Electroencephalography; Epilepsies, Myoclonic; Epilepsy	1992
Unresponsiveness to etretinate during anticonvulsant therapy. Dermatology (Basel, Switzerland), 1992, Volume: 185, Issue:1 Topics: Adolescent; Carbamazepine; Drug Interactions; Epilepsy, Tonic-Clonic; Etretinate; Female; Humans; Pi	1992
[The course of pregnancy and teratogenicity of antiepileptic agents in 66 patients with epilepsy]. Schweizer Archiv fur Neurologie und Psychiatrie (Zurich, Switzerland : 1985), 1991, Volume: 142, Issue:5 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combin	1991
Startle epilepsy--a case report. Indian journal of medical sciences, 1991, Volume: 45, Issue:5 Topics: Acoustic Stimulation; Carbamazepine; Cerebral Cortex; Child; Dose-Response Relationship, Drug; Epile	1991
Captopril as adjunctive treatment in catamenial epilepsy. The New Zealand medical journal, 1991, Aug-28, Volume: 104, Issue:918 Topics: Adult; Captopril; Carbamazepine; Drug Administration Schedule; Epilepsy, Tonic-Clonic; Female; Human	1991
A case of depression responding to spontaneous epilepsy but not ECT. The British journal of psychiatry : the journal of mental science, 1991, Volume: 159 Topics: Aged; Carbamazepine; Cerebral Cortex; Depressive Disorder; Electroconvulsive Therapy; Electroencepha	1991
[Enzyme induction and anticonvulsants]. Schweizer Archiv fur Neurologie und Psychiatrie (Zurich, Switzerland : 1985), 1987, Volume: 138, Issue:4 Topics: Adolescent; Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Carbamaz	1987
Mood disorders in the psychoneurologic borderland: three cases of responsiveness to carbamazepine. The American journal of psychiatry, 1989, Volume: 146, Issue:1 Topics: Adult; Anticonvulsants; Bipolar Disorder; Carbamazepine; Depressive Disorder; Drug Therapy, Combinat	1989
Sustained attention during the interictal period of mentally normal children with epilepsy or febrile convulsions, and the influence of anticonvulsants and seizures on attention. The Japanese journal of psychiatry and neurology, 1989, Volume: 43, Issue:3 Topics: Anticonvulsants; Attention; Carbamazepine; Child; Drug Therapy, Combination; Epilepsies, Partial; Ep	1989
[Carbamazepine causes skin eruption, fever and lymphadenopathy]. Duodecim; laaketieteellinen aikakauskirja, 1989, Volume: 105, Issue:8 Topics: Adolescent; Adult; Carbamazepine; Drug Eruptions; Epilepsy, Tonic-Clonic; Female; Fever; Humans; Lym	1989
[Bilateral shoulder dislocation fractures, femoral neck and vertebral fractures: a remarkable combination of injuries during an epileptic seizure]. Aktuelle Traumatologie, 1985, Volume: 15, Issue:4 Topics: Adult; Bone Screws; Bone Wires; Carbamazepine; Diabetes Complications; Epilepsy; Epilepsy, Tonic-Clo	1985
Interaction between carbamazepine and theophylline. The New Zealand medical journal, 1986, Feb-12, Volume: 99, Issue:795 Topics: Asthma; Carbamazepine; Child; Drug Interactions; Epilepsy, Tonic-Clonic; Female; Half-Life; Humans;	1986
[Single evening administration of slow release carbamazepine]. Der Nervenarzt, 1986, Volume: 57, Issue:7 Topics: Adolescent; Adult; Biotransformation; Carbamazepine; Drug Administration Schedule; Epilepsies, Parti	1986
[Clinical significance of serum concentration of carbamazepine orally administered to epileptic patients]. Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1986, Volume: 19, Issue:4 Topics: Administration, Oral; Adolescent; Adult; Aged; Carbamazepine; Child; Epilepsy, Tonic-Clonic; Female;	1986
[Determination of blood carbamazepine and its application in antiepileptic treatment]. Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1986, Volume: 19, Issue:4 Topics: Adolescent; Adult; Carbamazepine; Child; Chromatography, High Pressure Liquid; Epilepsies, Partial;	1986
Hyperdensity on CT after seizure: a pitfall. Journal of child neurology, 1987, Volume: 2, Issue:4 Topics: Carbamazepine; Cerebral Cortex; Child; Electroencephalography; Epilepsy, Tonic-Clonic; Evoked Potent	1987
[Rolandi epilepsy--a frequent seizure disorder in childhood. Symptomatology, electroencephalography, etiology, therapy, prognosis]. Der Nervenarzt, 1988, Volume: 59, Issue:1 Topics: Adolescent; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsies, Par	1988
Metabolism of magnesium and zinc in patients treated with antiepileptic drugs and with magnesium lactate. Magnesium, 1987, Volume: 6, Issue:6 Topics: Adult; Anticonvulsants; Carbamazepine; Diazepam; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Erythroc	1987
Episodic twilight state with severe autonomic symptoms in an epileptic patient. The Japanese journal of psychiatry and neurology, 1988, Volume: 42, Issue:4 Topics: Amygdala; Autonomic Nervous System; Carbamazepine; Child; Cognition Disorders; Consciousness Disorde	1988
[Side effects of anticonvulsants on the peripheral nervous system and vestibulo-ocular functions]. Fortschritte der Neurologie-Psychiatrie, 1985, Volume: 53, Issue:1 Topics: Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe;	1985
Treatment for teenagers with epilepsy. British medical journal (Clinical research ed.), 1985, May-11, Volume: 290, Issue:6479 Topics: Adolescent; Carbamazepine; Epilepsy, Tonic-Clonic; Female; Humans; Valproic Acid	1985
[Antiepileptic monotherapy and combination therapy of simple focal seizures]. Fortschritte der Neurologie-Psychiatrie, 1985, Volume: 53, Issue:12 Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Therapy, Combination; Ele	1985
Coarse features in epilepsy as a consequence of anticonvulsant therapy. Report of cases in two pairs of identical twins. Lancet (London, England), 1973, Nov-17, Volume: 2, Issue:7838 Topics: Acromegaly; Adult; Anticonvulsants; Carbamazepine; Child; Diazepam; Diseases in Twins; Epilepsy; Epi	1973
Epilepsy. The Practitioner, 1974, Volume: 213, Issue:1276 SPEC Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effec	1974
[Severe rachitic osteopathy during long-term anticonvulsant treatment]. Deutsche medizinische Wochenschrift (1946), 1973, May-18, Volume: 98, Issue:20 Topics: Administration, Oral; Alkaline Phosphatase; Anticonvulsants; Biopsy; Calcium; Carbamazepine; Child;	1973
Drug treatment of epilepsy in childhood. British medical journal, 1969, Nov-22, Volume: 4, Issue:5681 Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Absence; Epil	1969
[Therapy of epilepsy. The causes and consequences of inadequate treatment]. Deutsche medizinische Wochenschrift (1946), 1972, Oct-13, Volume: 97, Issue:41 Topics: Acridines; Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Barbiturates; Carbamazepine; Child	1972
[Treatment of epilepsy with carbamazepine]. Harefuah, 1972, Feb-15, Volume: 82, Issue:4 Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Child, Preschool; Epilepsy, Tonic-Clonic; Female; Hum	1972
Carbamazepine (tegretol) in the long-term treatment of grand mal epilepsy. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Aug-05, Volume: 46, Issue:31 Topics: Administration, Oral; Adult; Anticonvulsants; Carbamazepine; Epilepsy, Tonic-Clonic; Humans; Male; M	1972
The treatment of epileptic children with carbamazepine. Follow-up studies of clinical course and EEG. Epilepsia, 1972, Volume: 13, Issue:6 Topics: Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Epilepsy, Tempo	1972
Primary reading epilepsy. The Medical journal of Australia, 1969, May-17, Volume: 1, Issue:20 Topics: Adolescent; Adult; Brain Stem; Carbamazepine; Drug Synergism; Electric Stimulation; Electroencephalo	1969
[Effects of tegretol therapy in different groups of epileptic patients in a psychiatric hospital]. Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1968, Aug-31, Volume: 92, Issue:4 Topics: Adolescent; Adult; Carbamazepine; Dibenzazepines; Electroencephalography; Epilepsies, Partial; Epile	1968
[Successful results with carbamazepine (tegretol) in the treatment of severe epilepsy and its characteriopathic manifestations]. Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1968, Aug-31, Volume: 92, Issue:4 Topics: Adult; Carbamazepine; Character; Dibenzazepines; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; E	1968
[Tegretol treatment of epilepsy]. Lakartidningen, 1970, Sep-16, Volume: 67, Issue:38 Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Dibenzazepines; Epilepsy; Epilepsy, Temporal Lobe; Ep	1970
[Carbamazepine in the therapy of childhood epilepsy]. Deutsche medizinische Wochenschrift (1946), 1970, Nov-20, Volume: 95, Issue:47 Topics: Adolescent; Anticonvulsants; Behavior; Body Weight; Carbamazepine; Child; Child, Preschool; Chronic	1970
[Action of G. 32,883 on various severe forms of epilepsy]. Lyon medical, 1969, Apr-06, Volume: 221, Issue:14 Topics: Adolescent; Adult; Carbamazepine; Child; Dibenzazepines; Epilepsy, Tonic-Clonic; Female; Humans; Mal	1969
[Basic principles of epilepsy therapy]. Zeitschrift fur arztliche Fortbildung, 1970, Dec-15, Volume: 64, Issue:24 Topics: Anticonvulsants; Barbiturates; Benzazepines; Carbamazepine; Epilepsy; Epilepsy, Absence; Epilepsy, T	1970
[Clinical and electroencephalographic evaluation of the action of Tegretol in cases of epilepsy]. Neurologia i neurochirurgia polska, 1971, Volume: 5, Issue:3 Topics: Adolescent; Adult; Aged; Carbamazepine; Drug Tolerance; Electroencephalography; Epilepsy; Epilepsy,	1971
[In cerebral attacks: Tegretal]. Zeitschrift fur Allgemeinmedizin, 1970, Jun-10, Volume: 46, Issue:16 Topics: Adolescent; Adult; Carbamazepine; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Middle Aged; Trigeminal	1970
Antiepileptic and psychotropic effect of carbamazepine (Tegretol) in the treatment of psychomotor epilepsy. Epilepsia, 1971, Volume: 12, Issue:4 Topics: Adult; Carbamazepine; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Evalu	1971

carbamazepine and Convulsions, Grand Mal