Page last updated: 2024-10-24

carbamazepine and Cardiovascular Diseases

carbamazepine has been researched along with Cardiovascular Diseases in 12 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
"The aim of the study was to investigate risk factors for cardiovascular disease in patients with epilepsy using the new antiepileptic drug levetiracetam (LEV), compared with patients taking carbamazepine (CBZ) or lamotrigine (LTG)."7.76Cardiovascular risk factors in epilepsy patients taking levetiracetam, carbamazepine or lamotrigine. ( Gjerstad, L; Luef, G; Mørkrid, L; Rauchenzauner, M; Svalheim, S; Taubøll, E, 2010)
"The aim of the study was to investigate risk factors for cardiovascular disease in patients with epilepsy using the new antiepileptic drug levetiracetam (LEV), compared with patients taking carbamazepine (CBZ) or lamotrigine (LTG)."3.76Cardiovascular risk factors in epilepsy patients taking levetiracetam, carbamazepine or lamotrigine. ( Gjerstad, L; Luef, G; Mørkrid, L; Rauchenzauner, M; Svalheim, S; Taubøll, E, 2010)
"Although mania defines bipolar I disorder, depressive episodes and symptoms dominate the longitudinal course of, and disproportionately account for morbidity and mortality in, bipolar disorders."2.66Bipolar disorders. ( Berk, M; Brietzke, E; Goldstein, BI; Kessing, LV; López-Jaramillo, C; Majeed, A; Malhi, GS; Mansur, RB; McIntyre, RS; Nierenberg, AA; Rosenblat, JD; Vieta, E; Vinberg, M; Young, AH, 2020)
" When prescribing these drugs to patients of this age bracket, treatment should be based not only on the diagnosis and seizure type but also on the propensity of the drugs for adverse effects and their drug-drug interactions."2.48Choice of antiepileptic drugs for the elderly: possible drug interactions and adverse effects. ( Dostic, M; Jankovic, SM, 2012)
"Clinically significant cardiovascular toxicity occurs rarely in patients with toxic carbamazepine concentrations."1.29Cardiovascular effects of carbamazepine toxicity. ( Apfelbaum, JD; Bossart, PJ; Caravati, EM; Kerns, WP; Larsen, G, 1995)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's2 (16.67)18.2507
2000's3 (25.00)29.6817
2010's4 (33.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Larsson, D1
Baftiu, A1
Johannessen Landmark, C1
von Euler, M1
Kumlien, E1
Åsberg, S1
Zelano, J1
McIntyre, RS1
Berk, M1
Brietzke, E1
Goldstein, BI1
López-Jaramillo, C1
Kessing, LV1
Malhi, GS1
Nierenberg, AA1
Rosenblat, JD1
Majeed, A1
Vieta, E1
Vinberg, M1
Young, AH1
Mansur, RB1
Harit, D1
Aggarwal, A1
Kalra, S1
Chhillar, N1
Pulido Fontes, L1
Pulido Fontes, M1
Quesada Jiménez, P1
Muruzabal Pérez, J1
Mendioroz Iriarte, M1
Svalheim, S1
Luef, G1
Rauchenzauner, M1
Mørkrid, L1
Gjerstad, L2
Taubøll, E2
Jankovic, SM1
Dostic, M1
Kilbourne, AM1
Post, EP1
Bauer, MS1
Zeber, JE1
Copeland, LA1
Good, CB1
Pincus, HA1
Badiou, S1
Breton, H1
Peyriere, H1
Charasson, V1
Crespel, A1
Gelisse, P1
Cristol, JP1
Hillaire-Buys, D1
Apfelbaum, JD1
Caravati, EM1
Kerns, WP1
Bossart, PJ1
Larsen, G1
Quinn, MJ1
Fitzgerald, DJ1
Isojärvi, JI1
Pakarinen, AJ1
van Parys, J1
Rättyä, J1
Harbo, HF1
Dale, PO1
Fauser, BC1
Koivunen, R1
Knip, M1
Tapanainen, JS1
Muuronen, A1
Kaste, M1
Nikkilä, EA1
Tolppanen, EM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Levetiracetam, Carbamazepine and Lamotrigine and Hormonal Side Effects in Adult Males and Females.[NCT00460070]240 participants (Actual)Observational2007-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for carbamazepine and Cardiovascular Diseases

ArticleYear
Bipolar disorders.
    Lancet (London, England), 2020, 12-05, Volume: 396, Issue:10265

    Topics: Adolescent; Adult; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; B

2020
Choice of antiepileptic drugs for the elderly: possible drug interactions and adverse effects.
    Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:1

    Topics: Aged; Animals; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Choice Behavior; Drug Intera

2012
Ticlopidine and clopidogrel.
    Circulation, 1999, Oct-12, Volume: 100, Issue:15

    Topics: Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angina, Unstable; Aspirin; Bo

1999

Trials

1 trial available for carbamazepine and Cardiovascular Diseases

ArticleYear
Comparison of carbamazepine and oxcarbazepine effects on aminothiol levels.
    European journal of clinical pharmacology, 2008, Volume: 64, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Cysteine; Dipeptides; Ep

2008

Other Studies

8 other studies available for carbamazepine and Cardiovascular Diseases

ArticleYear
Association Between Antiseizure Drug Monotherapy and Mortality for Patients With Poststroke Epilepsy.
    JAMA neurology, 2022, 02-01, Volume: 79, Issue:2

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Cohort Studies; Dr

2022
Effect of Carbamazepine and Valproate Monotherapy on Cardiovascular Risks in Epileptic Children.
    Pediatric neurology, 2015, Volume: 53, Issue:1

    Topics: Anticonvulsants; Apolipoproteins A; Apolipoproteins B; Blood Chemical Analysis; Carbamazepine; Cardi

2015
Comparative case-control study of homocysteine, vitamin B
    Neurologia (Barcelona, Spain), 2017, Volume: 32, Issue:7

    Topics: Adult; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Case-Control Studies; Epilepsy; Fema

2017
Cardiovascular risk factors in epilepsy patients taking levetiracetam, carbamazepine or lamotrigine.
    Acta neurologica Scandinavica. Supplementum, 2010, Issue:190

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Comorbidity; Epilepsy; F

2010
Therapeutic drug and cardiovascular disease risk monitoring in patients with bipolar disorder.
    Journal of affective disorders, 2007, Volume: 102, Issue:1-3

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Cardiovascular Diseases; Drug Monitori

2007
Cardiovascular effects of carbamazepine toxicity.
    Annals of emergency medicine, 1995, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Aged; Carbamazepine; Cardiovascular Diseases; Child; Child, Preschool; Electrocar

1995
Altered ovarian function and cardiovascular risk factors in valproate-treated women.
    The American journal of medicine, 2001, Volume: 111, Issue:4

    Topics: Adult; Analysis of Variance; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Case-Control S

2001
Mortality from ischaemic heart disease among patients using anticonvulsive drugs: a case-control study.
    British medical journal (Clinical research ed.), 1985, Nov-23, Volume: 291, Issue:6507

    Topics: Aged; Anticonvulsants; Barbiturates; Carbamazepine; Cardiovascular Diseases; Cerebrovascular Disorde

1985