Page last updated: 2024-10-24

carbamazepine and Brittle Bone Disease

carbamazepine has been researched along with Brittle Bone Disease in 2 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Research Excerpts

ExcerptRelevanceReference
"The inherited brittle bone disease osteogenesis imperfecta (OI) is commonly caused by COL1A1 and COL1A2 mutations that disrupt the collagen I triple helix."5.72The effect of carbamazepine on bone structure and strength in control and osteogenesis imperfecta (Col1a2 ( Bateman, JF; Blank, M; Crimeen-Irwin, B; Gooi, JH; Kung, LHW; Lamandé, SR; McGregor, NE; Poulton, IJ; Rowley, L; Sims, NA; Walker, EC, 2022)
"The inherited brittle bone disease osteogenesis imperfecta (OI) is commonly caused by COL1A1 and COL1A2 mutations that disrupt the collagen I triple helix."1.72The effect of carbamazepine on bone structure and strength in control and osteogenesis imperfecta (Col1a2 ( Bateman, JF; Blank, M; Crimeen-Irwin, B; Gooi, JH; Kung, LHW; Lamandé, SR; McGregor, NE; Poulton, IJ; Rowley, L; Sims, NA; Walker, EC, 2022)
"The short height and the reported bone fractures could be compatible with a mild form of osteogenesis imperfecta, previously described in one case associated with SUNCT."1.35SUNCT syndrome or first division trigeminal neuralgia associated with cerebellar hypoplasia. ( Bartolozzi, ML; Guidi, L; Panconesi, A, 2009)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Blank, M1
McGregor, NE1
Rowley, L1
Kung, LHW1
Crimeen-Irwin, B1
Poulton, IJ1
Walker, EC1
Gooi, JH1
Lamandé, SR1
Sims, NA1
Bateman, JF1
Panconesi, A1
Bartolozzi, ML1
Guidi, L1

Other Studies

2 other studies available for carbamazepine and Brittle Bone Disease

ArticleYear
The effect of carbamazepine on bone structure and strength in control and osteogenesis imperfecta (Col1a2
    Journal of cellular and molecular medicine, 2022, Volume: 26, Issue:14

    Topics: Animals; Carbamazepine; Collagen; Collagen Type I; Disease Models, Animal; Humans; Male; Mice; Mutat

2022
SUNCT syndrome or first division trigeminal neuralgia associated with cerebellar hypoplasia.
    The journal of headache and pain, 2009, Volume: 10, Issue:6

    Topics: Amines; Arnold-Chiari Malformation; Carbamazepine; Cerebellum; Cranial Fossa, Posterior; Cyclohexane

2009