Page last updated: 2024-10-24

carbamazepine and Bradyarrhythmia

carbamazepine has been researched along with Bradyarrhythmia in 29 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Research Excerpts

ExcerptRelevanceReference
"A 74-year-old male, diagnosed with classic trigeminal neuralgia treated with 200 mg/12 h of carbamazepine, who visited due to a worsening of the pain in the trigeminal V1-V2 region."7.88[Lacosamide associated with high-degree block in a patient with trigeminal neuralgia]. ( Cantero-Lozano, D; Garces-Anton, E; Garces-Redondo, M; Garrido-Fernandez, A; Lopez-Bravo, A; Marin-Gracia, M; Navarro-Perez, MP; Santos-Lasaosa, S, 2018)
"The authors present a patient with carbamazepine-induced bradycardia-tachycardia syndrome, a rare type of drug-induced sinus node dysfunction."7.68Carbamazepine-induced bradycardia-tachycardia syndrome with pharmacological analysis and concurrent ECG monitoring. ( Hayashi, T; Morooka, S; Takabatake, Y; Takayanagi, K; Yamaguchi, H, 1990)
"A case is reported of water intoxication and cardiac conduction disturbances occurring as a late complication of carbamazepine therapy for trigeminal neuralgia."7.66Carbamazepine therapy complicated by nodal bradycardia and water intoxication. ( Byrne, E; Chambers, DG; Rice, JP; Wong, CH, 1979)
"Carbamazepine is a first line drug in the treatment of epilepsy and trigeminal neuralgia, but may exert negative chronotropic and dromotropic effects on the cardiac conduction system."5.28Carbamazepine induced bradycardia--a problem in general or only in susceptible patients? A 24-h long-term electrocardiogram study. ( Bergfeldt, L; Edhag, O; Kennebäck, G; Spina, E; Tomson, T, 1992)
" After excluding a possible interaction by long-term Carbamazepine treatment, the diagnosis of the Ictal bradycardia syndrome was made in view of the simultaneous occurrence of severe bradycardia and epileptic activity recorded on electro-encephalography."4.84[The ictal bradycardia syndrome: a case report and review of the literature]. ( Aissi, K; Bagnères, D; Demoux, AL; Francès, Y; Granel, B; Mechulan, A; Rossi, P; Sbragia, P; Somma-Mauvais, H, 2007)
"A patient with sinus bradycardia and atrioventricular block, induced by carbamazepine, prompted an extensive literature review of all previously reported cases."4.78Carbamazepine-induced cardiac dysfunction. Characterization of two distinct clinical syndromes. ( Berger, R; Kasarskis, EJ; Kuo, CS; Nelson, KR, 1992)
"A 74-year-old male, diagnosed with classic trigeminal neuralgia treated with 200 mg/12 h of carbamazepine, who visited due to a worsening of the pain in the trigeminal V1-V2 region."3.88[Lacosamide associated with high-degree block in a patient with trigeminal neuralgia]. ( Cantero-Lozano, D; Garces-Anton, E; Garces-Redondo, M; Garrido-Fernandez, A; Lopez-Bravo, A; Marin-Gracia, M; Navarro-Perez, MP; Santos-Lasaosa, S, 2018)
"day-1), carbamazepine, levomepromazine and alprazolan, a severe shock with bradycardia (HR: 40 b."3.70[Severe intoxication probably from olanzapine (Zyprexa). Beneficial effect of glucagon]. ( Joye, F; Marion, F; Michoux, I; Orrillard, M; Parisot, R, 1999)
"The authors present a patient with carbamazepine-induced bradycardia-tachycardia syndrome, a rare type of drug-induced sinus node dysfunction."3.68Carbamazepine-induced bradycardia-tachycardia syndrome with pharmacological analysis and concurrent ECG monitoring. ( Hayashi, T; Morooka, S; Takabatake, Y; Takayanagi, K; Yamaguchi, H, 1990)
"A case is reported of water intoxication and cardiac conduction disturbances occurring as a late complication of carbamazepine therapy for trigeminal neuralgia."3.66Carbamazepine therapy complicated by nodal bradycardia and water intoxication. ( Byrne, E; Chambers, DG; Rice, JP; Wong, CH, 1979)
"Ictal asystole is a presumably rare but potentially fatal complication of seizures, most often of temporal lobe origin."1.37New onset left frontal lobe seizure presenting with ictal asystole. ( Anyanwu, C; Eldadah, Z; Enkiri, SA; Ghavami, F; Morrissey, RL; Motamedi, GK, 2011)
"Familial rectal pain is a very rare entity that must always be considered as a possible aetiology of any life-threatening event in an infant because of the availability of a very effective treatment."1.33Familial rectal pain: a familial autonomic disorder as a cause of paroxysmal attacks in the newborn baby. ( Arbuès, AS; Bednarek, N; Morville, P; Motte, J; Plouin, P; Sabouraud, P, 2005)
"Glossopharyngeal neuralgia is a rare disease."1.30Glossopharyngeal neuralgia: a study of 6 cases. ( Baykal, S; Ceylan, S; Duru, S; Karakuş, A; Koca, O, 1997)
"Her carbamazepine clearance was markedly decreased."1.30Carbamazepine-induced sinus node dysfunction and atrioventricular block in elderly women. ( Fujito, T; Hayashi, T; Hisauchi, I; Hoshi, K; Inoue, T; Kase, M; Maekawa, Y; Morooka, S; Nishimura, N; Sakai, Y; Takayanagi, K; Watanabe, J, 1998)
"Carbamazepine is a first line drug in the treatment of epilepsy and trigeminal neuralgia, but may exert negative chronotropic and dromotropic effects on the cardiac conduction system."1.28Carbamazepine induced bradycardia--a problem in general or only in susceptible patients? A 24-h long-term electrocardiogram study. ( Bergfeldt, L; Edhag, O; Kennebäck, G; Spina, E; Tomson, T, 1992)
"Treatment with phenytoin or carbamazepine resulted in nearly complete resolution of symptoms in all five patients."1.28Bradycardia and syncope as manifestations of partial epilepsy. ( Constantin, L; Dagli, RD; Fincham, RW; Martins, JB, 1990)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199010 (34.48)18.7374
1990's9 (31.03)18.2507
2000's3 (10.34)29.6817
2010's6 (20.69)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Marin-Gracia, M1
Cantero-Lozano, D1
Garces-Anton, E1
Lopez-Bravo, A1
Garrido-Fernandez, A1
Navarro-Perez, MP1
Santos-Lasaosa, S1
Garces-Redondo, M1
Mbizvo, GK1
Derry, C1
Davenport, R1
Heerey, A1
Nash, P1
Hennessy, M1
Miyahara, H1
Sonoda, K1
Okazaki, N1
Sekiguchi, K1
Kawano, T1
Akiyoshi, K1
Maeda, T1
Izumi, T1
Hewetson, K1
Enkiri, SA1
Ghavami, F1
Anyanwu, C1
Eldadah, Z1
Morrissey, RL1
Motamedi, GK1
Bednarek, N1
Arbuès, AS1
Motte, J1
Sabouraud, P1
Plouin, P1
Morville, P1
Mechulan, A1
Rossi, P1
Somma-Mauvais, H1
Sbragia, P1
Aissi, K1
Granel, B1
Bagnères, D1
Demoux, AL1
Francès, Y1
Meyrignac, C1
Berges, C1
Benhothman, A1
Toulette, K1
Tillement, JP1
Albengres, E1
Blatrix, C1
Kennebäck, G3
Ceylan, S1
Karakuş, A1
Duru, S1
Baykal, S1
Koca, O1
Takayanagi, K2
Hisauchi, I1
Watanabe, J1
Maekawa, Y1
Fujito, T1
Sakai, Y1
Hoshi, K1
Kase, M1
Nishimura, N1
Inoue, T1
Hayashi, T2
Morooka, S2
Joye, F1
Orrillard, M1
Marion, F1
Michoux, I1
Parisot, R1
Kaul, S1
Meena, AK1
Murthy, JM1
Herzberg, L1
Byrne, E1
Wong, CH1
Chambers, DG1
Rice, JP1
Taylor, PH1
Gray, K1
Bicknell, PG1
Rees, JR1
Jamshidi, A1
Masroor, MA1
Marx, P1
Müller, U1
Bergfeldt, L2
Tomson, T1
Spina, E1
Edhag, O1
Kasarskis, EJ1
Kuo, CS1
Berger, R1
Nelson, KR1
Yamaguchi, H1
Takabatake, Y1
Constantin, L1
Martins, JB1
Fincham, RW1
Dagli, RD1
Jacome, DE1
Seroppian, ER1
Benassi, E1
Bo, GP1
Cocito, L1
Maffini, M1
Loeb, C1
al-Ubaidy, SS1
Bakeen, G1
Killian, JM1
Fromm, GH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Electroacupuncture Therapy for Change of Pain in Classical Trigeminal Neuralgia[NCT03580317]120 participants (Actual)Interventional2018-07-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for carbamazepine and Bradyarrhythmia

ArticleYear
[The ictal bradycardia syndrome: a case report and review of the literature].
    Archives des maladies du coeur et des vaisseaux, 2007, Volume: 100, Issue:3

    Topics: Anticonvulsants; Arrhythmia, Sinus; Bradycardia; Carbamazepine; Echocardiography; Echocardiography,

2007
[Pacemaker in bradycardias is sometimes not necessary. Seponation of carbamazepine should be considered].
    Lakartidningen, 1997, Mar-12, Volume: 94, Issue:11

    Topics: Anticonvulsants; Bradycardia; Carbamazepine; Humans; Pacemaker, Artificial; Risk Factors

1997
Glossopharyngeal neuralgia with syncope.
    The Journal of laryngology and otology, 1977, Volume: 91, Issue:10

    Topics: Adult; Aged; Bradycardia; Carbamazepine; Female; Glossopharyngeal Nerve; Humans; Male; Middle Aged;

1977
Carbamazepine-induced cardiac dysfunction. Characterization of two distinct clinical syndromes.
    Archives of internal medicine, 1992, Volume: 152, Issue:1

    Topics: Bradycardia; Carbamazepine; Electrocardiography; Female; Heart Block; Humans; Middle Aged

1992

Trials

1 trial available for carbamazepine and Bradyarrhythmia

ArticleYear
Carbamazepine in the treatment of neuralgia. Use of side effects.
    Archives of neurology, 1968, Volume: 19, Issue:2

    Topics: Adult; Aged; Anticonvulsants; Bradycardia; Carbamazepine; Clinical Trials as Topic; Dibenzazepines;

1968

Other Studies

24 other studies available for carbamazepine and Bradyarrhythmia

ArticleYear
[An epileptic elderly with carbamazepine-induced bradycardia].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2022, Volume: 59, Issue:3

    Topics: Aged; Bradycardia; Carbamazepine; Epilepsy; Humans

2022
[Lacosamide associated with high-degree block in a patient with trigeminal neuralgia].
    Revista de neurologia, 2018, Mar-16, Volume: 66, Issue:6

    Topics: Aged; Anticonvulsants; Atrioventricular Block; Bradycardia; Carbamazepine; Cardiopulmonary Resuscita

2018
Ictal asystole: a diagnostic and management conundrum.
    The journal of the Royal College of Physicians of Edinburgh, 2019, Volume: 49, Issue:2

    Topics: Anticonvulsants; Bradycardia; Carbamazepine; Deja Vu; Epilepsy; Female; Heart Arrest; Humans; Lamotr

2019
The ictal bradycardia syndrome: persistence of seizures despite cardiac pacemaker implantation.
    Irish medical journal, 2014, Volume: 107, Issue:3

    Topics: Anticonvulsants; Bradycardia; Carbamazepine; Cardiac Pacing, Artificial; Electrocardiography; Electr

2014
Ictal bradycardia in an infant following surgical treatment for hemimegalencephaly.
    Pediatrics international : official journal of the Japan Pediatric Society, 2010, Volume: 52, Issue:1

    Topics: Anticonvulsants; Atrioventricular Block; Bradycardia; Carbamazepine; Electroencephalography; Epileps

2010
Blocking out the real diagnosis.
    Lancet (London, England), 2011, Jul-23, Volume: 378, Issue:9788

    Topics: Anticonvulsants; Atrioventricular Block; Bradycardia; Carbamazepine; Diagnostic Errors; Epilepsy; Hu

2011
New onset left frontal lobe seizure presenting with ictal asystole.
    Seizure, 2011, Volume: 20, Issue:10

    Topics: Adult; Anticonvulsants; Bradycardia; Carbamazepine; Electrocardiography; Electroencephalography; Fro

2011
Familial rectal pain: a familial autonomic disorder as a cause of paroxysmal attacks in the newborn baby.
    Epileptic disorders : international epilepsy journal with videotape, 2005, Volume: 7, Issue:4

    Topics: Amitriptyline; Anticonvulsants; Apnea; Autonomic Nervous System Diseases; Bradycardia; Bronchial Spa

2005
[Sinus bradycardia and sinoauricular block induced by carbamazepine].
    Presse medicale (Paris, France : 1983), 1983, Feb-26, Volume: 12, Issue:9

    Topics: Aged; Arrhythmia, Sinus; Bradycardia; Carbamazepine; Female; Heart Block; Humans; Sinoatrial Block

1983
Glossopharyngeal neuralgia: a study of 6 cases.
    Neurosurgical review, 1997, Volume: 20, Issue:3

    Topics: Adult; Analgesics, Non-Narcotic; Bradycardia; Carbamazepine; Cranial Nerve Diseases; Female; Glossop

1997
Carbamazepine-induced sinus node dysfunction and atrioventricular block in elderly women.
    Japanese heart journal, 1998, Volume: 39, Issue:4

    Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anticonvulsants; Bradycardia; Carbamazepine; Card

1998
[Severe intoxication probably from olanzapine (Zyprexa). Beneficial effect of glucagon].
    Annales francaises d'anesthesie et de reanimation, 1999, Volume: 18, Issue:6

    Topics: Adult; Alprazolam; Antipsychotic Agents; Benzodiazepines; Bradycardia; Carbamazepine; Disseminated I

1999
Carbamazepine induced bradycardia.
    Neurology India, 2000, Volume: 48, Issue:4

    Topics: Adult; Anticonvulsants; Bradycardia; Carbamazepine; Epilepsy; Female; Humans

2000
Carbamazepine and bradycardia.
    Lancet (London, England), 1978, May-20, Volume: 1, Issue:8073

    Topics: Aged; Bradycardia; Carbamazepine; Female; Heart Block; Humans; Trigeminal Neuralgia

1978
Carbamazepine therapy complicated by nodal bradycardia and water intoxication.
    Australian and New Zealand journal of medicine, 1979, Volume: 9, Issue:3

    Topics: Aged; Bradycardia; Carbamazepine; Female; Humans; Trigeminal Neuralgia; Water Intoxication

1979
Glossopharyngeal neuralgia with cardiac syncope: treatment with a permanent cardiac pacemaker and carbamazepine.
    Archives of internal medicine, 1976, Volume: 136, Issue:7

    Topics: Aged; Bradycardia; Carbamazepine; Electrocardiography; Female; Glossopharyngeal Nerve; Heart Arrest;

1976
[Glossopharyngeal neuralgia with cardiac arrhythmias (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, Mar-21, Volume: 100, Issue:12

    Topics: Aged; Arrhythmias, Cardiac; Atropine; Bradycardia; Carbamazepine; Female; Glossopharyngeal Nerve; He

1975
Carbamazepine induced bradycardia--a problem in general or only in susceptible patients? A 24-h long-term electrocardiogram study.
    Epilepsy research, 1992, Volume: 13, Issue:2

    Topics: Adult; Aged; Bradycardia; Carbamazepine; Electrocardiography; Humans; Middle Aged; Monitoring, Physi

1992
[Bradyarrhythmias induced by antiepileptics increase frequency of epileptic seizures].
    Lakartidningen, 1991, May-08, Volume: 88, Issue:19

    Topics: Aged; Bradycardia; Carbamazepine; Epilepsy; Humans; Male; Phenytoin

1991
Carbamazepine-induced bradycardia-tachycardia syndrome with pharmacological analysis and concurrent ECG monitoring.
    Journal of electrocardiology, 1990, Volume: 23, Issue:1

    Topics: Aged; Bradycardia; Carbamazepine; Electrocardiography; Female; Humans; Syndrome; Tachycardia, Suprav

1990
Bradycardia and syncope as manifestations of partial epilepsy.
    Journal of the American College of Cardiology, 1990, Mar-15, Volume: 15, Issue:4

    Topics: Adult; Bradycardia; Carbamazepine; Electrocardiography; Electroencephalography; Epilepsy, Temporal L

1990
Ictal bradycardia.
    The American journal of the medical sciences, 1988, Volume: 295, Issue:5

    Topics: Aged; Bradycardia; Carbamazepine; Confusion; Electrocardiography; Electroencephalography; Epilepsy,

1988
Carbamazepine and cardiac conduction disturbances.
    Annals of neurology, 1987, Volume: 22, Issue:2

    Topics: Bradycardia; Carbamazepine; Electrocardiography; Epilepsy, Temporal Lobe; Female; Heart Block; Human

1987
Paroxysmal glossopharyngeal neuralgia associated with cardiac arrest.
    The British journal of oral surgery, 1974, Volume: 11, Issue:3

    Topics: Adult; Atropine; Bradycardia; Carbamazepine; Glossopharyngeal Nerve; Heart Arrest; Humans; Male; Man

1974