Page last updated: 2024-10-24

carbamazepine and Body Weight

carbamazepine has been researched along with Body Weight in 66 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to evaluate the safety and efficacy of extended release carbamazepine (CBZ-ER) monotherapy in the treatment of pediatric bipolar disorder (BD)."9.14A prospective open-label trial of extended-release carbamazepine monotherapy in children with bipolar disorder. ( Aleardi, M; Biederman, J; Doyle, R; Georgiopoulos, A; Hammerness, P; Joshi, G; Kotarski, M; Mick, E; Walls, S; Williams, C; Wozniak, J, 2010)
"A proportion of patients undergoing epilepsy surgery, and receiving carbamazepine (CBZ), experience significant elevations in CBZ plasma concentrations, some with associated CBZ toxicity."9.11Risk factors for carbamazepine elevation and toxicity following epilepsy surgery. ( Bingaman, W; Hiremath, GK; Hovinga, C; Kotagal, P; Morris, H; Nelson, D; Wyllie, E, 2005)
"Changes in body weight were evaluated in 349 patients from a study comparing efficacy of add-on therapy with tiagabine (TGB), carbamazepine (CBZ) or phenytoin (PHT)."9.09Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin. ( Bertrand, ME; Deaton, RL; Hogan, RE; Sommerville, KW, 2000)
"The PPK model, using the power scaling of body weight, effectively elucidated the topiramate serum concentration profile ranging from pediatric to adult patients."7.85Population Pharmacokinetics of Topiramate in Japanese Pediatric and Adult Patients With Epilepsy Using Routinely Monitored Data. ( Ikeda, A; Ito, S; Matsubara, K; Sugimoto, M; Takeuchi, M; Yamamoto, S; Yano, I; Yonezawa, A, 2017)
"To prospectively evaluate the long-term impact of valproate (VPA) versus carbamazepine (CBZ) on anthropometric, hormonal, and metabolic parameters in young male patients treated for epilepsy."7.81Endocrine Effects of Valproate versus Carbamazepine in Males with Epilepsy: A Prospective Study. ( de Vries, L; Goldberg-Stern, H; Itzhaki, T; Landau, Z, 2015)
" This retrospective study of children with epilepsy, aged <12 years at enrollment, examined weight gain associated with valproic acid or carbamazepine monotherapy."7.74Lack of valproic acid-associated weight gain in prepubertal children. ( Baumann, RJ; Espinosa, PS; Mendiondo, MS; Robertson, WC; Salazar, JC; Yu, L, 2008)
" Since the effects of carbamazepine on substance P content are identical with previously described effects of lithium, an alteration in substance P neurotransmission may be one of the neurochemical bases of common clinical and behavioral effects of carbamazepine and lithium on affective disorders."7.67Effects of chronic treatment with trihexyphenidyl and carbamazepine alone or in combination with haloperidol on substance P content in rat brain: a possible implication of substance P in affective disorders. ( Mataga, N; Mitsushio, H; Takashima, M; Toru, M, 1988)
"Carbamazepine clearance was studied in Black paediatric epilepsy patients, 90 receiving monotherapy and 17 on combination therapy."7.67Carbamazepine clearance in paediatric epilepsy patients. Influence of body mass, dose, sex and co-medication. ( Summers, B; Summers, RS, 1989)
"The effect of carbamazepine on body weight was studied in 24 patients with affective illness."7.67Effect of carbamazepine on body weight in affectively ill patients. ( Joffe, RT; Post, RM; Uhde, TW, 1986)
"Oral carbamazepine has been shown to have antidiuretic activity in seven out of nine patients with neurohypophyseal diabetes insipidus."7.65Treatment of diabetes insipidus with carbamazepine. ( Wales, JK, 1975)
" Furthermore, the proposed population pharmacokinetic model of VPA can be used to design rational dosage regimens to achieve desirable serum concentrations."5.42A population pharmacokinetic model of valproic acid in pediatric patients with epilepsy: a non-linear pharmacokinetic model based on protein-binding saturation. ( Ding, J; Jiao, Z; Li, X; Lin, W; Miao, L; Wang, C; Wang, Y; Zhao, L; Zhao, Z, 2015)
" No clinically relevant differences were found for using body surface area or weight to explain between-patient variability, therefore the final model included the effects of body weight on apparent clearance (CL/F) and apparent volume of distribution (V/F) of MHD, and in addition, the effect of 3 concomitant anti-epileptic drugs (carbamazepine, phenobarbital and phenytoin) on CL/F of MHD."5.20Population pharmacokinetic analysis for 10-monohydroxy derivative of oxcarbazepine in pediatric epileptic patients shows no difference between Japanese and other ethnicities. ( Bouillon, T; Fink, M; Hirota, T; Sugiyama, I; Suzuki, H; Yamaguchi, M, 2015)
"Carbamazepine clearance was not associated with body weight or any parameterization of body size nor was age or race or any marker of hepatic or renal function in community dwelling elderly patients."5.16Population pharmacokinetics of carbamazepine in elderly patients. ( Birnbaum, AK; Brundage, RC; Collins, JF; Macias, FM; Punyawudho, B; Ramsay, ER, 2012)
"The extent of lamotrigine interactions was investigated dependent on age, gender, weight and dose of concomitant carbamazepine and/or valproic acid in 65 patients with epilepsy."5.16Impact of age, weight and concomitant treatment on lamotrigine pharmacokinetics. ( Brzaković, BB; Martinović, ZJ; Miljković, BR; Pokrajac, MV; Prostran, MŠ; Vezmar Kovačević, SD; Vučićević, KM, 2012)
"The aim of this study was to evaluate the safety and efficacy of extended release carbamazepine (CBZ-ER) monotherapy in the treatment of pediatric bipolar disorder (BD)."5.14A prospective open-label trial of extended-release carbamazepine monotherapy in children with bipolar disorder. ( Aleardi, M; Biederman, J; Doyle, R; Georgiopoulos, A; Hammerness, P; Joshi, G; Kotarski, M; Mick, E; Walls, S; Williams, C; Wozniak, J, 2010)
"A proportion of patients undergoing epilepsy surgery, and receiving carbamazepine (CBZ), experience significant elevations in CBZ plasma concentrations, some with associated CBZ toxicity."5.11Risk factors for carbamazepine elevation and toxicity following epilepsy surgery. ( Bingaman, W; Hiremath, GK; Hovinga, C; Kotagal, P; Morris, H; Nelson, D; Wyllie, E, 2005)
"Changes in body weight were evaluated in 349 patients from a study comparing efficacy of add-on therapy with tiagabine (TGB), carbamazepine (CBZ) or phenytoin (PHT)."5.09Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin. ( Bertrand, ME; Deaton, RL; Hogan, RE; Sommerville, KW, 2000)
"The PPK model, using the power scaling of body weight, effectively elucidated the topiramate serum concentration profile ranging from pediatric to adult patients."3.85Population Pharmacokinetics of Topiramate in Japanese Pediatric and Adult Patients With Epilepsy Using Routinely Monitored Data. ( Ikeda, A; Ito, S; Matsubara, K; Sugimoto, M; Takeuchi, M; Yamamoto, S; Yano, I; Yonezawa, A, 2017)
"The alterations observed in body composition with valproic acid in contrast to other AEDs like levetiracetam, carbamazepine and phenytoin could affect treatment response in epilepsy especially in subjects with already altered body composition status like obese and thin frail patients, which needs to be established by prospective studies (CTRI/2013/05/003701)."3.83Comparison of body composition in persons with epilepsy on conventional & new antiepileptic drugs. ( Gupta, YK; Kakkar, AK; Sarangi, SC; Tripathi, M, 2016)
"To prospectively evaluate the long-term impact of valproate (VPA) versus carbamazepine (CBZ) on anthropometric, hormonal, and metabolic parameters in young male patients treated for epilepsy."3.81Endocrine Effects of Valproate versus Carbamazepine in Males with Epilepsy: A Prospective Study. ( de Vries, L; Goldberg-Stern, H; Itzhaki, T; Landau, Z, 2015)
"The study comprised 40 children and adolescents with idiopathic epilepsy on either valproate or carbamazepine."3.76Growth hormone levels in children and adolescents with epilepsy. ( Al-Badani, AK; Aly, GS; El-Khayat, HA; Mamdouh, RM; Mohamed, EI; Tomoum, HY, 2010)
" This retrospective study of children with epilepsy, aged <12 years at enrollment, examined weight gain associated with valproic acid or carbamazepine monotherapy."3.74Lack of valproic acid-associated weight gain in prepubertal children. ( Baumann, RJ; Espinosa, PS; Mendiondo, MS; Robertson, WC; Salazar, JC; Yu, L, 2008)
" The multiple peak approach has been used to evaluate the effect of age, total body weight, dose, gender and comedication (carbamazepine-induced change) on population estimates of valproic acid relative clearance."3.69Detection of carbamazepine-induced changes in valproic acid relative clearance in man by simple pharmacokinetic screening. ( Aoyama, T; Higuchi, S; Honda, T; Ohdo, S; Yukawa, E, 1997)
" Since the effects of carbamazepine on substance P content are identical with previously described effects of lithium, an alteration in substance P neurotransmission may be one of the neurochemical bases of common clinical and behavioral effects of carbamazepine and lithium on affective disorders."3.67Effects of chronic treatment with trihexyphenidyl and carbamazepine alone or in combination with haloperidol on substance P content in rat brain: a possible implication of substance P in affective disorders. ( Mataga, N; Mitsushio, H; Takashima, M; Toru, M, 1988)
"Carbamazepine clearance was studied in Black paediatric epilepsy patients, 90 receiving monotherapy and 17 on combination therapy."3.67Carbamazepine clearance in paediatric epilepsy patients. Influence of body mass, dose, sex and co-medication. ( Summers, B; Summers, RS, 1989)
"The effect of carbamazepine on body weight was studied in 24 patients with affective illness."3.67Effect of carbamazepine on body weight in affectively ill patients. ( Joffe, RT; Post, RM; Uhde, TW, 1986)
"Oral carbamazepine has been shown to have antidiuretic activity in seven out of nine patients with neurohypophyseal diabetes insipidus."3.65Treatment of diabetes insipidus with carbamazepine. ( Wales, JK, 1975)
"Delavirdine is a non-nucleoside reverse transcriptase inhibitor used in combination regimens for the treatment of HIV-1 infection."2.71Population pharmacokinetics of delavirdine and N-delavirdine in HIV-infected individuals. ( Dicenzo, R; DiFrancesco, R; Fischl, M; Forrest, A; Friedland, G; Morse, GD; Para, M; Pollard, R; Shelton, M; Smith, PF, 2005)
"Treatment with carbamazepine (CBZ) affects cholesterol concentrations, but little is known about the precise nature and underlying mechanisms of changes in lipoprotein metabolism."2.70Carbamazepine increases atherogenic lipoproteins: mechanism of action in male adults. ( Berthold, HK; Brämswig, S; Kerksiek, A; Luers, C; Sudhop, T; Von Bergmann, K, 2002)
"Lamotrigine (LTG) is a new antiepileptic drug (AED), chemically unrelated to the drugs in current use."2.68Serum concentrations of lamotrigine in epileptic patients: the influence of dose and comedication. ( Jürgens, U; May, TW; Rambeck, B, 1996)
"To compare carbamazepine pharmacokinetic parameters between obese and lean subjects following the administration of a single 200-mg tablet."2.68Carbamazepine pharmacokinetics in obese and lean subjects. ( Berry, EM; Caraco, Y; Levy, M; Zylber-Katz, E, 1995)
"Carbamazepine (CBZ) is a widely used antiepileptic drug with large interindividual variability in serum concentrations."1.48Effects of CYP3A5 and UGT2B7 variants on steady-state carbamazepine concentrations in Chinese epileptic patients. ( Huang, YT; Lu, Q; Qu, J; Qu, Q; Shu, Y; Xiang, DX; Xu, P, 2018)
" Furthermore, the proposed population pharmacokinetic model of VPA can be used to design rational dosage regimens to achieve desirable serum concentrations."1.42A population pharmacokinetic model of valproic acid in pediatric patients with epilepsy: a non-linear pharmacokinetic model based on protein-binding saturation. ( Ding, J; Jiao, Z; Li, X; Lin, W; Miao, L; Wang, C; Wang, Y; Zhao, L; Zhao, Z, 2015)
"ADMS rats dominantly exhibited myokymia, neuromyotonia and generalized tonic-clonic seizures."1.38Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures. ( Baulac, S; Ishida, S; Kaneko, S; Kuwamura, M; Mashimo, T; Nishio, T; Ohno, Y; Sakamoto, Y; Serikawa, T; Takizawa, A, 2012)
"The derived models describe well VPA clearance in terms of characteristics of Serbian pediatric and adult epileptic patients, offering a basis for rational individualization of VPA dosage regimens."1.36Factors influencing valproate pharmacokinetics in children and adults. ( Jankovic, S; Jankovic, SM; Milovanovic, JR, 2010)
"Air-puff thresholds (mechanical allodynia), pin prick responses (mechanical hyperalgesia), and spontaneous scratching behavior were examined 3 days before surgery and at 3, 7, 10, 14, 17, 21, 24, 30, and 40 days after surgery."1.35Compression of the trigeminal ganglion produces prolonged nociceptive behavior in rats. ( Ahn, DK; Bae, YC; Han, SR; Ju, JS; Kim, BC; Lee, MK; Lim, EJ; Yang, GY, 2009)
"There were 23 patients with convulsions, including 13 with benign convulsions, 9 with febrile seizures, and 1 with epilepsy."1.35Clinical characteristics of benign convulsions with rotavirus gastroenteritis. ( Furukawa, S; Ichiyama, T; Kajimoto, M; Matsushige, T; Motoyama, M; Shiraishi, M, 2009)
"To develop a population pharmacokinetic model to evaluate the effects of variety of covariates on clearance of carbamazepine (CBZ) and its main metabolite carbamazepine-10,11-epoxide (CBZE) in Chinese population."1.32Population pharmacokinetic modeling of steady state clearance of carbamazepine and its epoxide metabolite from sparse routine clinical data. ( Jiao, Z; Shi, XJ; Zhao, ZG; Zhong, MK, 2004)
" Pharmacokinetic interactions between antiepileptic drugs represent a major complication of epilepsy treatment with polytherapy."1.31Investigation of phenobarbital-carbamazepine-valproic acid interactions using population pharmacokinetic analysis for optimisation of antiepileptic drug therapy: an overview. ( Yukawa, E, 2000)
"37 x weight (kg); Absorption rate constant = 0."1.31Population pharmacokinetic modeling of steady state carbamazepine clearance in children, adolescents, and adults. ( Charles, B; Hooper, WD; Parke, J; Reith, DM, 2001)
"The individualization of carbamazepine (CBZ) dosage regimen based on estimation of pharmacokinetic (PK) parameters and measurement of serum drug concentration in epileptic patients can help to control epilepsy."1.31Bayesian estimation of six different sets of carbamazepine pharmacokinetic parameters in Egyptian adult epileptic patients. ( EL Desoky, ES; Kandil, MR, 2002)
"Carbamazepine (CBZ) has been widely used for treatment of manic states."1.31Carbamazepine suppresses methamphetamine-induced Fos expression in a regionally specific manner in the rat brain. Possible neural substrates responsible for antimanic effects of mood stabilizers. ( Fujiwara, Y; Hamamura, T; Kuroda, S; Lee, Y; Miki, M; Ohashi, K, 2000)
" Patients received phenobarbitone as monotherapy or in combination with either of the antiepileptic drugs carbamazepine or valproic acid."1.30Detection of a drug-drug interaction on population-based phenobarbitone clearance using nonlinear mixed-effects modeling. ( Aoyama, T; Higuchi, S; Ohdo, S; To, H; Yukawa, E, 1998)
"Body weight was an important determinant of carbamazepine clearance (CL) but not volume of distribution (V)."1.29Bioavailability of controlled release carbamazepine estimated by mixed effect modelling. ( Ludden, TM; Miller, R, 1993)
" Steady-state trough CBZ serum concentrations, CBZ dosing history, concomitant drug administration, and other data from 45 patients were collected retrospectively."1.28Postinduction carbamazepine clearance in an adult psychiatric population. ( Crismon, ML; Godley, PJ; Martin, ES, 1991)
" These findings should therefore be considered when defining dosage regimens or interpreting serum drug concentrations."1.28Analysis of the factors influencing anti-epileptic drug concentrations--valproic acid. ( Aoyama, T; Higuchi, S; Hirata, K; Ieiri, I; Yamada, H, 1990)
"The teratogenicity of carbamazepine (CBZ) was investigated in Sprague-Dawley CD rats at doses of 0, 200, 400, and 600 mg/kg administered by gavage in corn oil on days 7-18 of gestation in a dosage volume of 2 ml/kg."1.28Teratogenicity of carbamazepine in rats. ( Acuff, KD; Minck, DR; Vorhees, CV; Weisenburger, WP, 1990)
" These findings suggest that the dosage of zonisamide in epileptic patients might need to be varied depending on the comedication."1.27Comparative pharmacokinetics of zonisamide (CI-912) in epileptic patients on carbamazepine or phenytoin monotherapy. ( Buchanan, RA; Friel, PN; Levy, RH; McLean, JR; Ojemann, LM; Shastri, RA; Wilensky, AJ, 1986)

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-199016 (24.24)18.7374
1990's14 (21.21)18.2507
2000's19 (28.79)29.6817
2010's17 (25.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Galappatthy, P1
Liyanage, CK1
Lucas, MN1
Jayasekara, DTLM1
Abhayaratna, SA1
Weeraratne, C1
De Abrew, K1
Gunaratne, PS1
Gamage, R1
Wijeyaratne, CN1
Lu, Q1
Huang, YT1
Shu, Y1
Xu, P1
Xiang, DX1
Qu, Q1
Qu, J1
Ding, J1
Wang, Y1
Lin, W1
Wang, C1
Zhao, L1
Li, X1
Zhao, Z1
Miao, L1
Jiao, Z2
Goldberg-Stern, H1
Itzhaki, T1
Landau, Z1
de Vries, L1
Sugiyama, I1
Bouillon, T1
Yamaguchi, M1
Suzuki, H1
Hirota, T1
Fink, M1
Sarangi, SC1
Tripathi, M1
Kakkar, AK1
Gupta, YK1
Takeuchi, M1
Yano, I1
Ito, S1
Sugimoto, M1
Yamamoto, S1
Yonezawa, A1
Ikeda, A1
Matsubara, K1
Espinosa, PS1
Salazar, JC1
Yu, L1
Mendiondo, MS1
Robertson, WC1
Baumann, RJ1
Ahn, DK1
Lim, EJ1
Kim, BC1
Yang, GY1
Lee, MK1
Ju, JS1
Han, SR1
Bae, YC1
Motoyama, M1
Ichiyama, T1
Matsushige, T1
Kajimoto, M1
Shiraishi, M1
Furukawa, S1
Rauchenzauner, M1
Griesmacher, A1
Tatarczyk, T1
Haberlandt, E1
Strasak, A1
Zimmerhackl, LB1
Falkensammer, G1
Luef, G1
Högler, W1
Li, ZH1
Zlabek, V1
Velisek, J1
Grabic, R1
Machova, J1
Randak, T1
Joshi, G1
Wozniak, J1
Mick, E1
Doyle, R1
Hammerness, P1
Georgiopoulos, A1
Kotarski, M1
Aleardi, M1
Williams, C1
Walls, S1
Biederman, J1
El-Khayat, HA1
Aly, GS1
Tomoum, HY1
Mamdouh, RM1
Al-Badani, AK1
Mohamed, EI1
Jankovic, SM1
Milovanovic, JR1
Jankovic, S1
Cansu, A2
Ekinci, O2
Serdaroglu, A2
Gürgen, SG1
Erdogan, D1
Coskun, ZK1
Tunc, L1
Cinaz, P1
Ishida, S1
Sakamoto, Y1
Nishio, T1
Baulac, S1
Kuwamura, M1
Ohno, Y1
Takizawa, A1
Kaneko, S1
Serikawa, T1
Mashimo, T1
Punyawudho, B1
Ramsay, ER1
Brundage, RC1
Macias, FM1
Collins, JF1
Birnbaum, AK1
Brzaković, BB1
Vezmar Kovačević, SD1
Vučićević, KM1
Miljković, BR1
Martinović, ZJ1
Pokrajac, MV1
Prostran, MŠ1
Christensen, HD1
Rayburn, WF1
Parker, KM1
Gonzalez, CL1
Gold, KP1
Shi, XJ1
Zhao, ZG1
Zhong, MK1
Himmerich, H1
Koethe, D1
Schuld, A1
Yassouridis, A1
Pollmächer, T1
Smith, PF1
Dicenzo, R1
Forrest, A1
Shelton, M1
Friedland, G1
Para, M1
Pollard, R1
Fischl, M1
DiFrancesco, R1
Morse, GD1
Hiremath, GK1
Kotagal, P1
Bingaman, W1
Hovinga, C1
Wyllie, E1
Morris, H1
Nelson, D1
Weisler, RH1
Hirschfeld, R1
Cutler, AJ1
Gazda, T1
Ketter, TA1
Keck, PE1
Swann, A1
Kalali, A1
Smith, DF1
Leuschner, U1
Walther, H1
Liu, H2
Delgado, MR2
Miller, R1
Ludden, TM1
Caraco, Y1
Zylber-Katz, E1
Berry, EM1
Levy, M1
Isojärvi, JI1
Laatikainen, TJ1
Knip, M1
Pakarinen, AJ1
Juntunen, KT1
Myllylä, VV1
May, TW1
Rambeck, B2
Jürgens, U1
Yukawa, E3
Honda, T1
Ohdo, S2
Higuchi, S4
Aoyama, T4
Kofman, O1
Li, PP1
Warsh, JJ1
To, H1
Sudhop, T2
Bauer, J1
Elger, CE1
von Bergmann, K2
Lee, Y1
Hamamura, T1
Ohashi, K1
Miki, M1
Fujiwara, Y1
Kuroda, S1
Hogan, RE1
Bertrand, ME1
Deaton, RL1
Sommerville, KW1
Reith, DM2
Appleton, DB1
Hooper, W1
Eadie, MJ1
Hooper, WD1
Parke, J1
Charles, B1
Brämswig, S1
Kerksiek, A1
Luers, C1
Berthold, HK1
EL Desoky, ES1
Kandil, MR1
Bonhomme-Faivre, L1
Forestier, F1
Auchère, D1
Soursac, M1
Orbach-Arbouys, S1
Farinotti, R1
Pauwels, O1
Yamashita, H1
Kazawa, T1
Minatogawa, Y1
Ebisawa, T1
Yamauchi, T1
Wales, JK1
Martin, ES1
Crismon, ML1
Godley, PJ1
Ichikou, N1
Ieiri, I2
Hirata, K2
Yamada, H2
Vorhees, CV1
Acuff, KD1
Weisenburger, WP1
Minck, DR1
Mitsushio, H1
Takashima, M1
Mataga, N1
Toru, M1
Hönack, D1
Löscher, W1
Summers, B1
Summers, RS1
Sucheston, ME1
Hayes, TG1
Eluma, FO1
Conti, I1
Guiso, G1
Urso, R1
Caccia, S1
Joffe, RT1
Post, RM1
Uhde, TW1
Ojemann, LM1
Shastri, RA1
Wilensky, AJ1
Friel, PN1
Levy, RH1
McLean, JR1
Buchanan, RA1
Hudson, JI1
Pope, HG1
Jonas, JM1
Yurgelun-Todd, D1
May, T1
Hooshmand, H1
Meinders, AE1
Cejka, V1
Robertson, GL1
Johannessen, SI1
Strandjord, RE1
Fichsel, H1
Heyer, R1

Reviews

2 reviews available for carbamazepine and Body Weight

ArticleYear
Extended-release carbamazepine capsules as monotherapy in bipolar disorder : pooled results from two randomised, double-blind, placebo-controlled trials.
    CNS drugs, 2006, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Bipolar Disorder; Body Weight; Capsules; Carbamazepine; Ca

2006
Toxic effects of anticonvulsants: general principles.
    Pediatrics, 1974, Volume: 53, Issue:4

    Topics: Adrenocorticotropic Hormone; Adult; Anticonvulsants; Benzodiazepinones; Body Surface Area; Body Weig

1974

Trials

13 trials available for carbamazepine and Body Weight

ArticleYear
Population pharmacokinetic analysis for 10-monohydroxy derivative of oxcarbazepine in pediatric epileptic patients shows no difference between Japanese and other ethnicities.
    Drug metabolism and pharmacokinetics, 2015, Volume: 30, Issue:2

    Topics: Administration, Oral; Adolescent; Age Factors; Anticonvulsants; Asian People; Biotransformation; Bod

2015
A prospective open-label trial of extended-release carbamazepine monotherapy in children with bipolar disorder.
    Journal of child and adolescent psychopharmacology, 2010, Volume: 20, Issue:1

    Topics: Antimanic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Body Weight; Carb

2010
Serum insulin, cortisol, leptin, neuropeptide Y, galanin and ghrelin levels in epileptic children receiving oxcarbazepine.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2011, Volume: 15, Issue:6

    Topics: Adolescent; Anticonvulsants; Blood Glucose; Body Weight; Carbamazepine; Child; Child, Preschool; Epi

2011
Population pharmacokinetics of carbamazepine in elderly patients.
    Therapeutic drug monitoring, 2012, Volume: 34, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Rel

2012
Impact of age, weight and concomitant treatment on lamotrigine pharmacokinetics.
    Journal of clinical pharmacy and therapeutics, 2012, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Area Under Curve; Body Weight; Carbamazepine; Child

2012
Plasma levels of leptin and endogenous immune modulators during treatment with carbamazepine or lithium.
    Psychopharmacology, 2005, Volume: 179, Issue:2

    Topics: Adult; Antimanic Agents; Bipolar Disorder; Body Mass Index; Body Weight; Carbamazepine; Female; Huma

2005
Population pharmacokinetics of delavirdine and N-delavirdine in HIV-infected individuals.
    Clinical pharmacokinetics, 2005, Volume: 44, Issue:1

    Topics: Adolescent; Adult; Anti-HIV Agents; Body Weight; Carbamazepine; Delavirdine; Double-Blind Method; Dr

2005
Risk factors for carbamazepine elevation and toxicity following epilepsy surgery.
    Seizure, 2005, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Body Weight; Carbamazepine; Child; Child, Preschool

2005
Influence of sex, age, weight, and carbamazepine dose on serum concentrations, concentration ratios, and level/dose ratios of carbamazepine and its metabolites.
    Therapeutic drug monitoring, 1994, Volume: 16, Issue:5

    Topics: Aging; Body Weight; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilep

1994
Carbamazepine pharmacokinetics in obese and lean subjects.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:9

    Topics: Adolescent; Adult; Anticonvulsants; Body Weight; Carbamazepine; Female; Half-Life; Humans; Male; Mid

1995
Serum concentrations of lamotrigine in epileptic patients: the influence of dose and comedication.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:5

    Topics: Adult; Age Factors; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; D

1996
Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin.
    Epilepsy research, 2000, Volume: 41, Issue:1

    Topics: Anticonvulsants; Body Weight; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Epileps

2000
Carbamazepine increases atherogenic lipoproteins: mechanism of action in male adults.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:2

    Topics: Adult; Anticonvulsants; Arteriosclerosis; Body Composition; Body Weight; Carbamazepine; Cholestanol;

2002

Other Studies

51 other studies available for carbamazepine and Body Weight

ArticleYear
Obstetric outcomes and effects on babies born to women treated for epilepsy during pregnancy in a resource limited setting: a comparative cohort study.
    BMC pregnancy and childbirth, 2018, Jun-14, Volume: 18, Issue:1

    Topics: Abortion, Spontaneous; Adolescent; Adult; Anticonvulsants; Body Height; Body Weight; Carbamazepine;

2018
Effects of CYP3A5 and UGT2B7 variants on steady-state carbamazepine concentrations in Chinese epileptic patients.
    Medicine, 2018, Volume: 97, Issue:30

    Topics: Adult; Anticonvulsants; Asian People; Body Weight; Carbamazepine; Cytochrome P-450 CYP3A; Epilepsy;

2018
A population pharmacokinetic model of valproic acid in pediatric patients with epilepsy: a non-linear pharmacokinetic model based on protein-binding saturation.
    Clinical pharmacokinetics, 2015, Volume: 54, Issue:3

    Topics: Adolescent; Age Factors; Anticonvulsants; Body Weight; Carbamazepine; Child; Child, Preschool; Drug

2015
Endocrine Effects of Valproate versus Carbamazepine in Males with Epilepsy: A Prospective Study.
    Hormone research in paediatrics, 2015, Volume: 83, Issue:5

    Topics: Adolescent; Anticonvulsants; Body Height; Body Weight; Carbamazepine; Child; Epilepsy; Humans; Male;

2015
Comparison of body composition in persons with epilepsy on conventional & new antiepileptic drugs.
    The Indian journal of medical research, 2016, Volume: 143, Issue:3

    Topics: Adult; Anticonvulsants; Benzodiazepines; Body Composition; Body Water; Body Weight; Carbamazepine; C

2016
Population Pharmacokinetics of Topiramate in Japanese Pediatric and Adult Patients With Epilepsy Using Routinely Monitored Data.
    Therapeutic drug monitoring, 2017, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Asian People; Body Weight; Carbamazepine; Child; Child, Pr

2017
Lack of valproic acid-associated weight gain in prepubertal children.
    Pediatric neurology, 2008, Volume: 39, Issue:3

    Topics: Adolescent; Anticonvulsants; Body Height; Body Mass Index; Body Weight; Carbamazepine; Child; Child,

2008
Compression of the trigeminal ganglion produces prolonged nociceptive behavior in rats.
    European journal of pain (London, England), 2009, Volume: 13, Issue:6

    Topics: Agar; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Body Weight; Carbamazepine; Facial Pain;

2009
Clinical characteristics of benign convulsions with rotavirus gastroenteritis.
    Journal of child neurology, 2009, Volume: 24, Issue:5

    Topics: Anticonvulsants; Body Weight; Carbamazepine; Child; Child, Preschool; Chlorides; Creatinine; Female;

2009
Chronic antiepileptic monotherapy, bone metabolism, and body composition in non-institutionalized children.
    Developmental medicine and child neurology, 2010, Volume: 52, Issue:3

    Topics: Anthropometry; Anticonvulsants; Body Composition; Body Height; Body Mass Index; Body Weight; Carbama

2010
Physiological condition status and muscle-based biomarkers in rainbow trout (Oncorhynchus mykiss), after long-term exposure to carbamazepine.
    Journal of applied toxicology : JAT, 2010, Volume: 30, Issue:3

    Topics: Algorithms; Animals; Anticonvulsants; Biomarkers; Body Weight; Carbamazepine; Catalase; DNA; Dose-Re

2010
Growth hormone levels in children and adolescents with epilepsy.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2010, Volume: 14, Issue:6

    Topics: Adolescent; Anthropometry; Body Weight; Carbamazepine; Chi-Square Distribution; Child; Developmental

2010
Factors influencing valproate pharmacokinetics in children and adults.
    International journal of clinical pharmacology and therapeutics, 2010, Volume: 48, Issue:11

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Body Weight; Carbamazepine; Child; Child, Pre

2010
Effects of chronic treatment with valproate and oxcarbazepine on testicular development in rats.
    Seizure, 2011, Volume: 20, Issue:3

    Topics: Animals; Animals, Newborn; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship,

2011
Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures.
    Brain research, 2012, Jan-30, Volume: 1435

    Topics: Animals; Antiemetics; Biophysical Phenomena; Biotinylation; Body Weight; Carbamazepine; Cells, Cultu

2012
Chronic prenatal exposure to carbamazepine and perinatal outcomes of C3H/He mice.
    American journal of obstetrics and gynecology, 2004, Volume: 190, Issue:1

    Topics: Animals; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Female; Mice

2004
Population pharmacokinetic modeling of steady state clearance of carbamazepine and its epoxide metabolite from sparse routine clinical data.
    Journal of clinical pharmacy and therapeutics, 2004, Volume: 29, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Asian People; Body Weight; Carbamazepine;

2004
Lithium and carbamazepine: effects on learned taste aversion and open field behavior in rats.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:4

    Topics: Animals; Avoidance Learning; Behavior, Animal; Body Weight; Carbamazepine; Chlorides; Lithium; Lithi

1983
[Problems of therapeutic service in carbamazepine therapy].
    Zeitschrift fur arztliche Fortbildung, 1980, Aug-01, Volume: 74, Issue:15

    Topics: Adult; Biotransformation; Body Weight; Carbamazepine; Child; Drug Interactions; Humans; Phenytoin

1980
The influence of polytherapy on the relationships between serum carbamazepine and its metabolites in epileptic children.
    Epilepsy research, 1994, Volume: 17, Issue:3

    Topics: Aging; Anticonvulsants; Body Weight; Carbamazepine; Child; Chromatography, High Pressure Liquid; Dru

1994
Bioavailability of controlled release carbamazepine estimated by mixed effect modelling.
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:3

    Topics: Absorption; Adolescent; Adult; Biological Availability; Body Weight; Carbamazepine; Delayed-Action P

1993
Obesity and endocrine disorders in women taking valproate for epilepsy.
    Annals of neurology, 1996, Volume: 39, Issue:5

    Topics: Adult; Body Weight; Carbamazepine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Endocrine

1996
Detection of carbamazepine-induced changes in valproic acid relative clearance in man by simple pharmacokinetic screening.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:8

    Topics: Adolescent; Adult; Aging; Anticonvulsants; Body Weight; Carbamazepine; Child; Child, Preschool; Drug

1997
Lithium, but not carbamazepine, potentiates hyperactivity induced by intra-accumbens cholera toxin.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 59, Issue:1

    Topics: Adenosine Diphosphate Ribose; Analysis of Variance; Animals; Body Weight; Carbamazepine; Catalysis;

1998
Detection of a drug-drug interaction on population-based phenobarbitone clearance using nonlinear mixed-effects modeling.
    European journal of clinical pharmacology, 1998, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Body Weight; Carbamazepine; Child; Child, Preschool

1998
Increased high-density lipoprotein cholesterol in patients with epilepsy treated with carbamazepine: a gender-related study.
    Epilepsia, 1999, Volume: 40, Issue:4

    Topics: Adult; Age Factors; Ambulatory Care; Anticonvulsants; Blood Donors; Body Weight; Carbamazepine; Chol

1999
Carbamazepine suppresses methamphetamine-induced Fos expression in a regionally specific manner in the rat brain. Possible neural substrates responsible for antimanic effects of mood stabilizers.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 22, Issue:5

    Topics: Amphetamine-Related Disorders; Animals; Antimanic Agents; Bipolar Disorder; Body Weight; Brain; Carb

2000
Investigation of phenobarbital-carbamazepine-valproic acid interactions using population pharmacokinetic analysis for optimisation of antiepileptic drug therapy: an overview.
    Drug metabolism and drug interactions, 2000, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Biomarkers; Body Weight; Carbamazepine; Child; Child, Preschool;

2000
The effect of body size on the metabolic clearance of carbamazepine.
    Biopharmaceutics & drug disposition, 2000, Volume: 21, Issue:3

    Topics: Adolescent; Anticonvulsants; Body Height; Body Weight; Carbamazepine; Child; Cross-Sectional Studies

2000
Population pharmacokinetic modeling of steady state carbamazepine clearance in children, adolescents, and adults.
    Journal of pharmacokinetics and pharmacodynamics, 2001, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Biological Availability; Body Height; Body Surface

2001
Bayesian estimation of six different sets of carbamazepine pharmacokinetic parameters in Egyptian adult epileptic patients.
    Pharmacological research, 2002, Volume: 45, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Bayes Theorem; Body Weight; Carbamazepine; Egypt; Epilepsy, Toni

2002
Chronic administration of verapamil, ketoconazole and carbamazepine: impact on immunological parameters.
    International journal of pharmaceutics, 2002, May-15, Volume: 238, Issue:1-2

    Topics: Animals; Anticonvulsants; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1

2002
Factors contributing to carbamazepine-macrolide interactions.
    Pharmacological research, 2002, Volume: 45, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Anti-Bacterial Agents; Anticonvulsants; Body Weight; Carbamazepine;

2002
Time-course of hepatic cytochrome p450 subfamily induction by chronic carbamazepine treatment in rats.
    The international journal of neuropsychopharmacology, 2002, Volume: 5, Issue:1

    Topics: Animals; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Body Weight; Carbamazepi

2002
Treatment of diabetes insipidus with carbamazepine.
    Lancet (London, England), 1975, Nov-15, Volume: 2, Issue:7942

    Topics: Adolescent; Adult; Arginine Vasopressin; Body Water; Body Weight; Carbamazepine; Diabetes Insipidus;

1975
Postinduction carbamazepine clearance in an adult psychiatric population.
    Pharmacotherapy, 1991, Volume: 11, Issue:4

    Topics: Adult; Aged; Biological Availability; Body Weight; Carbamazepine; Female; Humans; Intestinal Absorpt

1991
Analysis of the factors influencing anti-epileptic drug concentrations--carbamazepine.
    Journal of clinical pharmacy and therapeutics, 1990, Volume: 15, Issue:5

    Topics: Aging; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Female; Huma

1990
Analysis of the factors influencing anti-epileptic drug concentrations--valproic acid.
    Journal of clinical pharmacy and therapeutics, 1990, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Aging; Aspartate Aminotransferases; Body Weight; Carbamazepine; Dose-Response Rel

1990
Teratogenicity of carbamazepine in rats.
    Teratology, 1990, Volume: 41, Issue:3

    Topics: Animals; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Female; Rats; Rats, Inbred St

1990
Effects of chronic treatment with trihexyphenidyl and carbamazepine alone or in combination with haloperidol on substance P content in rat brain: a possible implication of substance P in affective disorders.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:3

    Topics: Animals; Body Weight; Brain Chemistry; Carbamazepine; Dopamine; Dose-Response Relationship, Drug; ga

1988
Amygdala-kindling as a model for chronic efficacy studies on antiepileptic drugs: experiments with carbamazepine.
    Neuropharmacology, 1989, Volume: 28, Issue:6

    Topics: Amygdala; Animals; Anticonvulsants; Body Temperature; Body Weight; Carbamazepine; Electric Stimulati

1989
Carbamazepine clearance in paediatric epilepsy patients. Influence of body mass, dose, sex and co-medication.
    Clinical pharmacokinetics, 1989, Volume: 17, Issue:3

    Topics: Biological Availability; Black People; Body Weight; Carbamazepine; Child; Child, Preschool; Drug Int

1989
Relationship between ossification and body weight of the CD-1 mouse fetus exposed in utero to anticonvulsant drugs.
    Teratogenesis, carcinogenesis, and mutagenesis, 1986, Volume: 6, Issue:6

    Topics: Animals; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Female; Fetu

1986
Inhibitory and inducing effects of denzimol on carbamazepine metabolism in the rat.
    Pharmacology, 1987, Volume: 35, Issue:5

    Topics: Animals; Anticonvulsants; Body Weight; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome

1987
Effect of carbamazepine on body weight in affectively ill patients.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:6

    Topics: Adult; Bipolar Disorder; Body Weight; Carbamazepine; Depressive Disorder; Double-Blind Method; Femal

1986
Comparative pharmacokinetics of zonisamide (CI-912) in epileptic patients on carbamazepine or phenytoin monotherapy.
    Therapeutic drug monitoring, 1986, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Body Weight; Carbamazepine; Drug Therapy, Combination; Epilepsy;

1986
Treatment of anorexia nervosa with antidepressants.
    Journal of clinical psychopharmacology, 1985, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Anorexia Nervosa; Antidepressive Agents; Antidepressive Agents, Tricyclic; Body W

1985
Serum concentrations of valproic acid: influence of dose and comedication.
    Therapeutic drug monitoring, 1985, Volume: 7, Issue:4

    Topics: Adolescent; Adult; Body Weight; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epileps

1985
The antidiuretic action of carbamazepine in man.
    Clinical science and molecular medicine, 1974, Volume: 47, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Arginine; Body Weight; Carbamazepine; Creatine; Diabetes In

1974
The concentration of carbamazepine (Tegretol R) in serum and in cerebrospinal fluid in patients with epilepsy.
    Acta neurologica Scandinavica. Supplementum, 1972, Volume: 51

    Topics: Adult; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Protein Bindi

1972
[Carbamazepine in the therapy of childhood epilepsy].
    Deutsche medizinische Wochenschrift (1946), 1970, Nov-20, Volume: 95, Issue:47

    Topics: Adolescent; Anticonvulsants; Behavior; Body Weight; Carbamazepine; Child; Child, Preschool; Chronic

1970