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carbamazepine and Autistic Disorder

carbamazepine has been researched along with Autistic Disorder in 17 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Autistic Disorder: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)

Research Excerpts

ExcerptRelevanceReference
"We herein report a case of new-onset epileptic seizures induced by carbamazepine in an individual with autism spectrum disorders (ASD)."7.72Carbamazepine may trigger new-onset epileptic seizures in an individual with autism spectrum disorders: a case report. ( Hashioka, S; Maekawa, T; Monji, A; Yanagimoto, K; Yoshida, I, 2004)
" Oxcarbazepine and lamotrigine were associated with increased occurrence of autism."4.95Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta-analysis. ( Cogo, E; D'Souza, J; Finkelstein, Y; Hemmelgarn, BR; Hutton, B; Kealey, R; MacDonald, H; Reynen, E; Rios, P; Soobiah, C; Straus, SE; Thavorn, K; Tricco, AC; Veroniki, AA; Yazdi, F, 2017)
" We differentiated and treated human SK-N-SH neuroblastoma cells with a mixture (fluoxetine, carbamazepine and venlafaxine) and valproate (used as a positive control to induce autism-associated profiles), followed by transcriptome analysis with RNA-Seq approach."3.83Psychoactive pharmaceuticals at environmental concentrations induce in vitro gene expression associated with neurological disorders. ( Kaushik, G; Thomas, MA; Xia, Y; Yang, L, 2016)
"We herein report a case of new-onset epileptic seizures induced by carbamazepine in an individual with autism spectrum disorders (ASD)."3.72Carbamazepine may trigger new-onset epileptic seizures in an individual with autism spectrum disorders: a case report. ( Hashioka, S; Maekawa, T; Monji, A; Yanagimoto, K; Yoshida, I, 2004)
"The carbamazepine studies were inconclusive."2.38Nonneuroleptic treatment of disruptive behavior in organic mental syndromes. ( Perry, PJ; Smith, DA, 1992)
"The association between autism spectrum disorders (ASD) and epilepsy has been extensively documented, and the estimated prevalence varies depending upon the selected population and the clinical characteristics."1.72Autism with Epilepsy: A Neuropsychopharmacology Update. ( Canitano, R; Palumbi, R; Scandurra, V, 2022)
"A majority of cases of idiopathic autism in children likely result from unknown environmental triggers in genetically susceptible individuals."1.46Dysregulation of autism-associated synaptic proteins by psychoactive pharmaceuticals at environmental concentrations. ( Kaushik, G; Pfau, JC; Thomas, MA; Xia, Y, 2017)
"Most cases of idiopathic autism spectrum disorder (ASD) likely result from unknown environmental triggers in genetically susceptible individuals."1.42Psychoactive pharmaceuticals as environmental contaminants may disrupt highly inter-connected nodes in an Autism-associated protein-protein interaction network. ( Aho, KA; Kaushik, G; Thomas, MA, 2015)
"Idiopathic autism, caused by genetic susceptibility interacting with unknown environmental triggers, has increased dramatically in the past 25 years."1.38Psychoactive pharmaceuticals induce fish gene expression profiles associated with human idiopathic autism. ( Klaper, RD; Thomas, MA, 2012)
"The role of adiponectin in autism is still debatable."1.36Variations of plasma leptin and adiponectin levels in autistic patients. ( Auteri, A; Blardi, P; Ceccatelli, L; de Lalla, A; Hayek, J; Vanessa, G, 2010)
"Citalopram was the most preferred antidepressant and Carbamazepine, the most preferred mood stabilizer/antiepileptic."1.35Use of medication for the management of behavior problems among adults with intellectual disabilities: a clinicians' consensus survey. ( Deb, S; Unwin, GL, 2008)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's2 (11.76)18.2507
2000's5 (29.41)29.6817
2010's7 (41.18)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Bjørk, MH1
Zoega, H1
Leinonen, MK1
Cohen, JM1
Dreier, JW1
Furu, K1
Gilhus, NE1
Gissler, M1
Hálfdánarson, Ó1
Igland, J1
Sun, Y1
Tomson, T1
Alvestad, S1
Christensen, J1
Canitano, R1
Palumbi, R1
Scandurra, V1
Veroniki, AA1
Rios, P1
Cogo, E1
Straus, SE1
Finkelstein, Y1
Kealey, R1
Reynen, E1
Soobiah, C1
Thavorn, K1
Hutton, B1
Hemmelgarn, BR1
Yazdi, F1
D'Souza, J1
MacDonald, H1
Tricco, AC1
Kaushik, G3
Xia, Y2
Pfau, JC1
Thomas, MA4
Aho, KA1
Yang, L1
Pedrini, M1
Noguera, A1
Vinent, J1
Torra, M1
Jiménez, R1
Blardi, P1
de Lalla, A1
Ceccatelli, L1
Vanessa, G1
Auteri, A1
Hayek, J1
Klaper, RD1
Miyajima, T1
Kumada, T1
Saito, K1
Fujii, T1
Renier, WO1
Monji, A1
Maekawa, T1
Yanagimoto, K1
Yoshida, I1
Hashioka, S1
Kapetanovic, S1
Unwin, GL1
Deb, S1
Smith, DA1
Perry, PJ1
Wong, SE1
Floyd, J1
Innocent, AJ1
Woolsey, JE1
Philippart, M1

Reviews

2 reviews available for carbamazepine and Autistic Disorder

ArticleYear
Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta-analysis.
    BMJ open, 2017, Jul-20, Volume: 7, Issue:7

    Topics: Anticonvulsants; Autistic Disorder; Bayes Theorem; Breast Feeding; Carbamazepine; Child; Epilepsy; F

2017
Nonneuroleptic treatment of disruptive behavior in organic mental syndromes.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:11

    Topics: Adrenergic beta-Antagonists; Antisocial Personality Disorder; Autistic Disorder; Carbamazepine; Deme

1992

Other Studies

15 other studies available for carbamazepine and Autistic Disorder

ArticleYear
Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability.
    JAMA neurology, 2022, 07-01, Volume: 79, Issue:7

    Topics: Anticonvulsants; Autism Spectrum Disorder; Autistic Disorder; Carbamazepine; Child; Cohort Studies;

2022
Autism with Epilepsy: A Neuropsychopharmacology Update.
    Genes, 2022, 10-08, Volume: 13, Issue:10

    Topics: Adolescent; Anticonvulsants; Autistic Disorder; Carbamazepine; Child; Epilepsy; Humans; Lamotrigine

2022
Dysregulation of autism-associated synaptic proteins by psychoactive pharmaceuticals at environmental concentrations.
    Neuroscience letters, 2017, Nov-20, Volume: 661

    Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Brain; Carbamazepine; Environment; Female; Flu

2017
Psychoactive pharmaceuticals as environmental contaminants may disrupt highly inter-connected nodes in an Autism-associated protein-protein interaction network.
    BMC bioinformatics, 2015, Volume: 16 Suppl 7

    Topics: Animals; Anticonvulsants; Antidepressive Agents, Second-Generation; Autistic Disorder; Brain; Carbam

2015
Psychoactive pharmaceuticals at environmental concentrations induce in vitro gene expression associated with neurological disorders.
    BMC genomics, 2016, 06-29, Volume: 17 Suppl 3

    Topics: Animals; Autistic Disorder; Carbamazepine; Cell Line, Tumor; Environmental Pollutants; Fluoxetine; G

2016
Acute oxcarbazepine overdose in an autistic boy.
    British journal of clinical pharmacology, 2009, Volume: 67, Issue:5

    Topics: Adolescent; Anticonvulsants; Autistic Disorder; Carbamazepine; Drug Overdose; Humans; Male; Oxcarbaz

2009
Variations of plasma leptin and adiponectin levels in autistic patients.
    Neuroscience letters, 2010, Jul-19, Volume: 479, Issue:1

    Topics: Adiponectin; Adolescent; Analysis of Variance; Antimanic Agents; Autistic Disorder; Body Mass Index;

2010
Psychoactive pharmaceuticals induce fish gene expression profiles associated with human idiopathic autism.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Animals; Autistic Disorder; Carbamazepine; Cell Adhesion Molecules; Cyclohexanols; Cyprinidae; Fluox

2012
Autism in siblings with autosomal dominant nocturnal frontal lobe epilepsy.
    Brain & development, 2013, Volume: 35, Issue:2

    Topics: Adolescent; Anticonvulsants; Asperger Syndrome; Autistic Disorder; Carbamazepine; Child; Child Devel

2013
Compulsive spitting as manifestation of temporal lobe epilepsy.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2004, Volume: 8, Issue:1

    Topics: Adolescent; Anticonvulsants; Autistic Disorder; Carbamazepine; Child; Compulsive Behavior; Dominance

2004
Carbamazepine may trigger new-onset epileptic seizures in an individual with autism spectrum disorders: a case report.
    European psychiatry : the journal of the Association of European Psychiatrists, 2004, Volume: 19, Issue:5

    Topics: Adult; Anticonvulsants; Autistic Disorder; Carbamazepine; Electroencephalography; Epilepsy, Tonic-Cl

2004
Oxcarbazepine in youths with autistic disorder and significant disruptive behaviors.
    The American journal of psychiatry, 2007, Volume: 164, Issue:5

    Topics: Adolescent; Adult; Anticonvulsants; Attention Deficit and Disruptive Behavior Disorders; Autistic Di

2007
Use of medication for the management of behavior problems among adults with intellectual disabilities: a clinicians' consensus survey.
    American journal of mental retardation : AJMR, 2008, Volume: 113, Issue:1

    Topics: Adult; Aggression; Antipsychotic Agents; Attitude of Health Personnel; Autistic Disorder; Carbamazep

2008
Applying a DRO schedule and compliance training to reduce aggressive and self-injurious behavior in an autistic man: a case report.
    Journal of behavior therapy and experimental psychiatry, 1991, Volume: 22, Issue:4

    Topics: Adult; Aggression; Autistic Disorder; Behavior Therapy; Carbamazepine; Combined Modality Therapy; Ha

1991
Clinical recognition of Rett syndrome.
    American journal of medical genetics. Supplement, 1986, Volume: 1

    Topics: Adolescent; Autistic Disorder; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Fema

1986