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carbamazepine and Astrocytoma

carbamazepine has been researched along with Astrocytoma in 8 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Research Excerpts

ExcerptRelevanceReference
"Inositol uptake was measured at concentrations of 25, 40 and 50 microM in human astrocytoma cell cultures treated for 1-3 weeks with pharmacologically relevant concentrations of LiCl, valproic acid or carbamazepine as well as in control cultures that had not been treated with any drug."7.70Chronic treatment of human astrocytoma cells with lithium, carbamazepine or valproic acid decreases inositol uptake at high inositol concentrations but increases it at low inositol concentrations. ( Belmaker, RH; Bersudsky, Y; Hertz, L; Simkin, M; Wolfson, M; Zinger, E, 2000)
" Patient suffered from tumor-related epilepsy, treated pharmacologically with carbamazepine."3.83Toxic epidermal necrolysis in patient with malignant astrocytoma. ( Bartnik, P; Kacperczyk, J; Kaczmarska-Turek, D; Krasnodębska-Kiljańska, M; Olszewska, M; Orlewski, J, 2016)
"Inositol uptake was measured at concentrations of 25, 40 and 50 microM in human astrocytoma cell cultures treated for 1-3 weeks with pharmacologically relevant concentrations of LiCl, valproic acid or carbamazepine as well as in control cultures that had not been treated with any drug."3.70Chronic treatment of human astrocytoma cells with lithium, carbamazepine or valproic acid decreases inositol uptake at high inositol concentrations but increases it at low inositol concentrations. ( Belmaker, RH; Bersudsky, Y; Hertz, L; Simkin, M; Wolfson, M; Zinger, E, 2000)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaczmarska-Turek, D1
Bartnik, P1
Kacperczyk, J1
Orlewski, J1
Olszewska, M1
Krasnodębska-Kiljańska, M1
Crespo Pérez, L1
Moreira Vicente, V1
Cano Ruiz, A1
Gobernado Serrano, JM1
Cobo Ibañez, N1
Milicua Salamero, JM1
Anneken, K1
Fischera, M1
Kolska, S1
Evers, S1
Gall, H1
Merk, H1
Scherb, W1
Sterry, W1
Wolfson, M1
Bersudsky, Y1
Zinger, E1
Simkin, M1
Belmaker, RH1
Hertz, L1
Bleggi-Torres, LF1
Gasparetto, EL1
Faoro, LN1
Hanel, R1
Grande, CV1
de Carvalho Neto, A1
de Noronha, L1
Lewin, E1
Ghosh, C1
Lazarus, HM1
Hewlett, JS1
Creger, RJ1

Reviews

1 review available for carbamazepine and Astrocytoma

ArticleYear
[Anticonvulsant hypersensitivity syndrome: an entity to be remembered].
    Gastroenterologia y hepatologia, 2009, Volume: 32, Issue:10

    Topics: Adolescent; Amines; Anemia, Hemolytic; Anticonvulsants; Astrocytoma; Brain Neoplasms; Carbamazepine;

2009

Trials

1 trial available for carbamazepine and Astrocytoma

ArticleYear
Fluctuation of serum phenytoin concentrations during autologous bone marrow transplant for primary central nervous system tumors.
    Journal of neuro-oncology, 1992, Volume: 12, Issue:1

    Topics: Adult; Anticonvulsants; Astrocytoma; Bone Marrow Transplantation; Brain Neoplasms; Carbamazepine; Fe

1992

Other Studies

6 other studies available for carbamazepine and Astrocytoma

ArticleYear
Toxic epidermal necrolysis in patient with malignant astrocytoma.
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2016, Volume: 40, Issue:235

    Topics: Astrocytoma; Bacterial Outer Membrane Proteins; Brain Neoplasms; Carbamazepine; Epilepsy; Female; Hu

2016
An unusual case of musicogenic epilepsy in a patient with a left fronto-temporal tumour.
    Journal of neurology, 2006, Volume: 253, Issue:11

    Topics: Anticonvulsants; Astrocytoma; Brain Neoplasms; Carbamazepine; Epilepsy, Reflex; Female; Functional L

2006
[Anticonvulsant hypersensitivity syndrome to carbamazepine].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1994, Volume: 45, Issue:7

    Topics: Adult; Anticonvulsants; Astrocytoma; Brain Neoplasms; Carbamazepine; Cerebral Cortex; Dose-Response

1994
Chronic treatment of human astrocytoma cells with lithium, carbamazepine or valproic acid decreases inositol uptake at high inositol concentrations but increases it at low inositol concentrations.
    Brain research, 2000, Feb-07, Volume: 855, Issue:1

    Topics: Antimanic Agents; Astrocytoma; Bipolar Disorder; Brain; Brain Neoplasms; Carbamazepine; Dose-Respons

2000
Pleomorphic xanthoastrocytoma: report of a case diagnosed by intraoperative cytopathological examination.
    Diagnostic cytopathology, 2001, Volume: 24, Issue:2

    Topics: Adolescent; Anticonvulsants; Astrocytoma; Brain Neoplasms; Carbamazepine; Cytodiagnosis; Giant Cells

2001
Effects of phenytoin on the release of 14C-adenine derivatives.
    Epilepsia, 1977, Volume: 18, Issue:3

    Topics: Adenine; Animals; Astrocytoma; Brain Neoplasms; Carbamazepine; Cells, Cultured; Cerebral Cortex; Hyp

1977