Page last updated: 2024-10-24

carbamazepine and Asthma

carbamazepine has been researched along with Asthma in 12 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Based on the assumption that bronchial asthma has not only inflammatory, but also certain neurogenic paroxysmal mechanism and pathophysiological links with other non-epileptic paroxysmal inflammatory diseases--migraine and trigeminal neuralgia, we decided to investigate efficacy of antiepileptic drug carbamazepine in patients with moderate persistent or severe asthma."9.12Bronchial asthma as neurogenic paroxysmal inflammatory disease: a randomized trial with carbamazepine. ( Lomia, M; Pruidze, M; Tchelidze, T, 2006)
"Based on the assumption that bronchial asthma has not only inflammatory, but also certain neurogenic paroxysmal mechanism and pathophysiological links with other non-epileptic paroxysmal inflammatory diseases--migraine and trigeminal neuralgia, we decided to investigate efficacy of antiepileptic drug carbamazepine in patients with moderate persistent or severe asthma."5.12Bronchial asthma as neurogenic paroxysmal inflammatory disease: a randomized trial with carbamazepine. ( Lomia, M; Pruidze, M; Tchelidze, T, 2006)
"Prednisolone and methylprednisolone pharmacokinetic parameters were evaluated in asthmatic children receiving concomitant anticonvulsant therapy."5.06Prednisolone and methylprednisolone kinetics in children receiving anticonvulsant therapy. ( Bartoszek, M; Brenner, AM; Szefler, SJ, 1987)
" Return of symptoms was seen with prednisone treatment for exacerbated asthma."3.71Functional changes and adverse reactions after successful treatment of hereditary myokymia: a case report. ( Keebler, P; Kinnett, D, 2001)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19906 (50.00)18.7374
1990's1 (8.33)18.2507
2000's4 (33.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Weaver, D1
Chorny, V1
Tewari, S1
Lomia, M1
Tchelidze, T1
Pruidze, M1
Singh, N1
Lee, T1
Cochrane, GM1
Amlot, P1
Rosenberry, KR1
Defusco, CJ1
Mansmann, HC1
McGeady, SJ1
Lewis, IJ1
Rosenbloom, L1
Czuczwar, SJ1
Gasior, M1
Kozicka, M1
Pietrasiewicz, T1
Turski, WA1
Kleinrok, Z1
Kinnett, D1
Keebler, P1
Abbott, MB1
Levin, RH1
von Wichert, P1
Mitchell, EA1
Dower, JC1
Green, RJ1
Bartoszek, M1
Brenner, AM1
Szefler, SJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomised, Placebo Controlled, Double Blind, Parallel Group 3-Months Study of Carbamazepine Efficacy in Moderate Persistent and Severe Asthma Therapy[NCT00153296]Phase 468 participants Interventional2004-08-31Completed
Study of Pharmacokinetic Variability of Glucocorticoids in Children[NCT02252237]146 participants (Actual)Observational2014-12-03Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for carbamazepine and Asthma

ArticleYear
What's new: newly approved drugs for children.
    Pediatrics in review, 2001, Volume: 22, Issue:10

    Topics: Adolescent; Age Factors; Albuterol; Androstadienes; Anticonvulsants; Asthma; Atovaquone; Attention D

2001

Trials

2 trials available for carbamazepine and Asthma

ArticleYear
Bronchial asthma as neurogenic paroxysmal inflammatory disease: a randomized trial with carbamazepine.
    Respiratory medicine, 2006, Volume: 100, Issue:11

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Anti-Asthmatic Agents; Anticonvulsa

2006
Prednisolone and methylprednisolone kinetics in children receiving anticonvulsant therapy.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:4

    Topics: Adolescent; Anticonvulsants; Asthma; Biological Availability; Carbamazepine; Child; Half-Life; Human

1987

Other Studies

9 other studies available for carbamazepine and Asthma

ArticleYear
Case 1: Joint Pain, Weight Loss, Fatigue, and Persistent Pleural Effusions in 17-year-old Boy.
    Pediatrics in review, 2015, Volume: 36, Issue:5

    Topics: Adolescent; Anticonvulsants; Arthralgia; Asthma; Carbamazepine; Diabetes Mellitus, Type 2; Diagnosis

2015
Carbamazepine in asthma: first do no harm!
    Respiratory medicine, 2007, Volume: 101, Issue:3

    Topics: Administration, Oral; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Carbamazepine; Drug Syne

2007
Pulmonary eosinophilia and asthma associated with carbamazepine.
    British medical journal (Clinical research ed.), 1981, Feb-07, Volume: 282, Issue:6262

    Topics: Asthma; Carbamazepine; Eosinophilia; Humans; Lung Diseases; Male; Middle Aged

1981
Reduced theophylline half-life induced by carbamazepine therapy.
    The Journal of pediatrics, 1983, Volume: 102, Issue:3

    Topics: Asthma; Carbamazepine; Child; Drug Interactions; Epilepsy; Female; Half-Life; Humans; Theophylline

1983
Glandular fever-like syndrome, pulmonary eosinophilia and asthma associated with carbamazepine.
    Postgraduate medical journal, 1982, Volume: 58, Issue:676

    Topics: Asthma; Carbamazepine; Child; Diagnosis, Differential; Fever; Humans; Infectious Mononucleosis; Male

1982
Influence of a potential anti-asthmatic drug, CR 2039, upon the anticonvulsive activity of conventional antiepileptics against maximal electroshock-induced seizures in mice.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:12

    Topics: Animals; Anticonvulsants; Asthma; Avoidance Learning; Benzamides; Bronchodilator Agents; Carbamazepi

1996
Functional changes and adverse reactions after successful treatment of hereditary myokymia: a case report.
    Archives of physical medicine and rehabilitation, 2001, Volume: 82, Issue:2

    Topics: Anti-Inflammatory Agents; Anticonvulsants; Asthma; Carbamazepine; Child; Diagnosis, Differential; Dr

2001
[Drug side-effects in the lung].
    Deutsche medizinische Wochenschrift (1946), 1978, Feb-10, Volume: 103, Issue:6

    Topics: Antineoplastic Agents; Asthma; Carbamazepine; Cromolyn Sodium; Drug-Related Side Effects and Adverse

1978
Interaction between carbamazepine and theophylline.
    The New Zealand medical journal, 1986, Feb-12, Volume: 99, Issue:795

    Topics: Asthma; Carbamazepine; Child; Drug Interactions; Epilepsy, Tonic-Clonic; Female; Half-Life; Humans;

1986