carbamazepine has been researched along with Anterior Optic Neuritis in 6 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Carbamazepine and oxcarbazepine were not immunosuppressive in lymphocyte-driven autoimmunity, but slowed the accumulation of disability in experimental autoimmune encephalomyelitis when administered during periods of the inflammatory penumbra after active lesion formation, and was shown to limit the development of neurodegeneration during optic neuritis in myelin-specific T cell receptor transgenic mice." | 3.80 | Lesional-targeting of neuroprotection to the inflammatory penumbra in experimental multiple sclerosis. ( Al-Izki, S; Amor, S; Baker, D; Browne, L; Clutterbuck, L; Edith Chan, AW; Garthwaite, J; Gerritsen, WH; Giovannoni, G; Hankey, DJ; Joel, SP; Lidster, K; Montoya, A; Peferoen-Baert, R; Perkins, V; Posada, C; Pryce, G; Selwood, DL; Ummenthum, K; van der Valk, P; von Kutzleben, SM, 2014) |
| "We present a rare case of subacute sclerosing panencephalitis with isolated bilateral optic neuritis as the only ocular finding without macular involvement." | 1.40 | Bilateral optic neuritis--the only ocular finding in a case of subacute sclerosing panencephalitis. ( Aksoy, A; Kadayifcilar, S; Ozer, PA; Ozkan, M; Sekeroglu, HT; Yuksel, D, 2014) |
| "Multiple sclerosis is an immune-mediated, demyelinating and neurodegenerative disease that currently lacks any neuroprotective treatments." | 1.39 | Neuroprotection in a novel mouse model of multiple sclerosis. ( Ahmed, Z; Baker, D; Baker, MD; Coffey, P; Giovannoni, G; Jackson, SJ; Lidster, K; Munro, P, 2013) |
| "Paroxysmal dysarthria and ataxia (7 cases), and tonic seizures (5 cases) were the most common types of attacks." | 1.25 | Paroxysmal attacks in multiple sclerosis. ( Ostermann, PO; Westerberg, CE, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ozer, PA | 1 |
| Ozkan, M | 1 |
| Sekeroglu, HT | 1 |
| Kadayifcilar, S | 1 |
| Yuksel, D | 1 |
| Aksoy, A | 1 |
| Lidster, K | 2 |
| Jackson, SJ | 1 |
| Ahmed, Z | 1 |
| Munro, P | 1 |
| Coffey, P | 1 |
| Giovannoni, G | 2 |
| Baker, MD | 1 |
| Baker, D | 2 |
| Al-Izki, S | 1 |
| Pryce, G | 1 |
| Hankey, DJ | 1 |
| von Kutzleben, SM | 1 |
| Browne, L | 1 |
| Clutterbuck, L | 1 |
| Posada, C | 1 |
| Edith Chan, AW | 1 |
| Amor, S | 1 |
| Perkins, V | 1 |
| Gerritsen, WH | 1 |
| Ummenthum, K | 1 |
| Peferoen-Baert, R | 1 |
| van der Valk, P | 1 |
| Montoya, A | 1 |
| Joel, SP | 1 |
| Garthwaite, J | 1 |
| Selwood, DL | 1 |
| Soysal, A | 1 |
| Dogan, P | 1 |
| Yuksel, B | 1 |
| Dayan, C | 1 |
| Arpaci, B | 1 |
| Ostermann, PO | 1 |
| Westerberg, CE | 1 |
| Mandel, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| OxCarbazepine as a Neuroprotective Agent in MS: A Phase 2a Trial[NCT02104661] | Phase 2 | 30 participants (Actual) | Interventional | 2014-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for carbamazepine and Anterior Optic Neuritis
| Article | Year |
|---|---|
Facial pain. 'Why does my face hurt, doctor?'.
Topics: Carbamazepine; Carotid Artery Diseases; Cranial Nerve Diseases; Diagnosis, Differential; Facial Pain | 1990 |
5 other studies available for carbamazepine and Anterior Optic Neuritis
| Article | Year |
|---|---|
Bilateral optic neuritis--the only ocular finding in a case of subacute sclerosing panencephalitis.
Topics: Anticonvulsants; Antiviral Agents; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalo | 2014 |
Neuroprotection in a novel mouse model of multiple sclerosis.
Topics: Animals; Anticonvulsants; Carbamazepine; Caspase 2; Disease Models, Animal; Evoked Potentials, Visua | 2013 |
Lesional-targeting of neuroprotection to the inflammatory penumbra in experimental multiple sclerosis.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzamides; Biological Specimen Ba | 2014 |
Encephalitis during interferon beta-1a treatment in a child with optic neuritis.
Topics: Adjuvants, Immunologic; Anticonvulsants; Antiviral Agents; Carbamazepine; Child; Encephalitis, Herpe | 2010 |
Paroxysmal attacks in multiple sclerosis.
Topics: Adult; Ataxia; Carbamazepine; Diplopia; Female; Functional Laterality; Humans; Hypesthesia; Male; Mi | 1975 |