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carbamazepine and Anemia, Aplastic

carbamazepine has been researched along with Anemia, Aplastic in 25 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.

Research Excerpts

ExcerptRelevanceReference
"Carbamazepine is an antiepileptic drug used in the treatment of epilepsy, trigeminal neuralgia, and bipolar disorder."4.31Acute lymphocytic leukemia in a patient with long-term carbamazepine exposure: Acute lymphoblastic leukemia that develops in a patient who has been using carbamazepine for a long time. ( Bagci, M; Sayin, S, 2023)
"Appropriate use of carbamazepine for the treatment of epilepsy is based on correct identification of the patient's seizure type."3.67How to initiate and maintain carbamazepine therapy in children and adults. ( Porter, RJ, 1987)
"Rare, serious adverse effects of antiepileptic drugs (AEDs) include hepatotoxicity and bone marrow suppression."2.38Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy. ( Wyllie, E; Wyllie, R, 1991)
" The findings of this study are comparable with those of other series assessing carbamazepine-associated adverse reactions in children and adults."2.37Carbamazepine side effects in children and adults. ( Pellock, JM, 1987)
"Carbamazepine treatment was subsequently discontinued, and the patient was treated with red blood cell transfusions, haptoglobin, and methylprednisolone."1.34Carbamazepine-induced hemolytic and aplastic crises associated with reduced glutathione peroxidase activity of erythrocytes. ( Fujii, H; Hatakeyama, N; Kanno, H; Kubo, N; Suzuki, N; Tachi, N; Tsutsumi, H; Yamamoto, M, 2007)
"A 53-yr-old man sequentially developed aplastic anemia from phenytoin and carbamazepine."1.27Anticonvulsant-induced aplastic anemia: increased susceptibility to toxic drug metabolites in vitro. ( Fine, DG; Gerson, WT; Sensenbrenner, LL; Spielberg, SP, 1983)
"Carbamazepine was found to cause statistically significant, but clinically insubstantial, decreases in white blood cell indexes."1.27Hematological effects of carbamazepine in patients with affective illness. ( Joffe, RT; Post, RM; Roy-Byrne, PP; Uhde, TW, 1985)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199017 (68.00)18.7374
1990's3 (12.00)18.2507
2000's3 (12.00)29.6817
2010's1 (4.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Sayin, S1
Bagci, M1
Fernández-Fernández, FJ1
Ameneiros-Lago, E1
Maceira-Quintás, C1
Handoko, KB1
Souverein, PC1
van Staa, TP1
Meyboom, RH1
Leufkens, HG1
Egberts, TC1
van den Bemt, PM1
Yamamoto, M1
Suzuki, N1
Hatakeyama, N1
Kubo, N1
Tachi, N1
Kanno, H1
Fujii, H1
Tsutsumi, H1
Gerson, WT1
Fine, DG1
Spielberg, SP1
Sensenbrenner, LL1
Hart, RG1
Easton, JD1
Foletti, GB1
Hirai, H1
Livingston, S1
Pauli, L1
Pruce, I1
Pisciotta, AV1
Wyllie, E1
Wyllie, R1
Betticher, DC1
Wolfisberg, HP1
Krapf, R1
Sobotka, JL1
Alexander, B1
Cook, BL1
Balon, R1
Berchou, R1
Ramsay, RE1
Pellock, JM1
Moore, NC1
Lerer, B1
Meyendorff, E1
Gershon, S1
Porter, RJ1
Canterbury, RJ1
Joffe, RT1
Post, RM1
Roy-Byrne, PP1
Uhde, TW1
Crill, WE1
Gayford, JJ1
Redpath, TH1
Saleh, AE1
Mendes de Leon, DE1
Fellows, WR1

Reviews

7 reviews available for carbamazepine and Anemia, Aplastic

ArticleYear
Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy.
    Epilepsia, 1991, Volume: 32 Suppl 5

    Topics: Anemia, Aplastic; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Monit

1991
A review of carbamazepine's hematologic reactions and monitoring recommendations.
    DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:12

    Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Carbamazepine; Child, Preschool; Female; Humans; Mal

1990
Hematologic side effects of psychotropic drugs.
    Psychosomatics, 1986, Volume: 27, Issue:2

    Topics: Agranulocytosis; Anemia, Aplastic; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents;

1986
Use of phenytoin and carbamazepine in treatment of epilepsy.
    Neurologic clinics, 1986, Volume: 4, Issue:3

    Topics: Anemia, Aplastic; Carbamazepine; Cerebellar Ataxia; Chemical and Drug Induced Liver Injury; Cognitio

1986
Carbamazepine side effects in children and adults.
    Epilepsia, 1987, Volume: 28 Suppl 3

    Topics: Adult; Agranulocytosis; Anemia, Aplastic; Carbamazepine; Chemical and Drug Induced Liver Injury; Chi

1987
Drugs 5 years later: carbamazepine.
    Annals of internal medicine, 1973, Volume: 79, Issue:6

    Topics: Agranulocytosis; Anemia, Aplastic; Anticonvulsants; Bone Marrow; Bone Marrow Cells; Carbamazepine; D

1973
The side-effects of carbamazepine.
    Proceedings of the Royal Society of Medicine, 1969, Volume: 62, Issue:6

    Topics: Amitriptyline; Anemia, Aplastic; Carbamazepine; Dibenzazepines; Gastrointestinal Diseases; Humans; I

1969

Other Studies

18 other studies available for carbamazepine and Anemia, Aplastic

ArticleYear
Acute lymphocytic leukemia in a patient with long-term carbamazepine exposure: Acute lymphoblastic leukemia that develops in a patient who has been using carbamazepine for a long time.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:2

    Topics: Anemia, Aplastic; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Neutropenia; Precursor Cell Lymp

2023
Aplastic anaemia following carbamazepine-induced drug reaction with eosinophilia and systemic symptoms syndrome.
    Internal medicine journal, 2019, Volume: 49, Issue:11

    Topics: Aged; Anemia, Aplastic; Carbamazepine; Drug Hypersensitivity Syndrome; Eosinophilia; Humans; Male

2019
Risk of aplastic anemia in patients using antiepileptic drugs.
    Epilepsia, 2006, Volume: 47, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Anticonvulsants; Carbamazepine; Case-Control Studi

2006
Carbamazepine-induced hemolytic and aplastic crises associated with reduced glutathione peroxidase activity of erythrocytes.
    International journal of hematology, 2007, Volume: 86, Issue:4

    Topics: Anemia, Aplastic; Bilirubin; Carbamazepine; Child, Preschool; Enzyme Activation; Erythrocytes; Gluta

2007
Anticonvulsant-induced aplastic anemia: increased susceptibility to toxic drug metabolites in vitro.
    Blood, 1983, Volume: 61, Issue:5

    Topics: Anemia, Aplastic; Carbamazepine; Female; Humans; Lymphocytes; Male; Microsomes; Middle Aged; Mutatio

1983
Carbamazepine and hematological monitoring.
    Annals of neurology, 1982, Volume: 11, Issue:3

    Topics: Adolescent; Anemia; Anemia, Aplastic; Carbamazepine; Female; Hematologic Diseases; Humans; Leukopeni

1982
[Clinical utilization of new anti-epileptic agents].
    Revue medicale de la Suisse romande, 2000, Volume: 120, Issue:9

    Topics: Acetates; Amines; Anemia, Aplastic; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dru

2000
[Two cases of erythroid hypoplasia caused by carbamazephine (Tegretol)(author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1977, Volume: 18, Issue:1

    Topics: Adult; Anemia, Aplastic; Carbamazepine; Humans; Male

1977
No proven relationship of carbamazepine therapy to blood dyscrasias.
    Neurology, 1978, Volume: 28, Issue:1

    Topics: Anemia, Aplastic; Carbamazepine; Humans

1978
Hematologic toxicity of carbamazepine.
    Advances in neurology, 1975, Volume: 11

    Topics: Adult; Aged; Anemia, Aplastic; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Female; Hu

1975
[Aplastic anemia in carbamazepine therapy].
    Schweizerische medizinische Wochenschrift, 1991, Apr-20, Volume: 121, Issue:16

    Topics: Aged; Anemia, Aplastic; Carbamazepine; Epilepsy; Humans; Male; Pancytopenia; Seizures; Sick Sinus Sy

1991
Three cases of carbamazepine toxicity.
    The American journal of psychiatry, 1985, Volume: 142, Issue:8

    Topics: Adult; Anemia, Aplastic; Bipolar Disorder; Carbamazepine; Chemical and Drug Induced Liver Injury; Dr

1985
How to initiate and maintain carbamazepine therapy in children and adults.
    Epilepsia, 1987, Volume: 28 Suppl 3

    Topics: Adult; Anemia, Aplastic; Carbamazepine; Child; Drug Administration Schedule; Epilepsy; Humans; Leuko

1987
The side effects of carbamazepine.
    The American journal of psychiatry, 1986, Volume: 143, Issue:3

    Topics: Anemia, Aplastic; Bipolar Disorder; Carbamazepine; Chemical and Drug Induced Liver Injury; Humans; P

1986
Hematological effects of carbamazepine in patients with affective illness.
    The American journal of psychiatry, 1985, Volume: 142, Issue:10

    Topics: Adult; Anemia; Anemia, Aplastic; Bipolar Disorder; Carbamazepine; Diagnosis, Differential; Erythrocy

1985
[Pancytopenia with fatal course during treatment with carbamazepine (Tegretol)].
    Nederlands tijdschrift voor geneeskunde, 1968, Nov-16, Volume: 112, Issue:46

    Topics: Analgesics; Anemia, Aplastic; Carbamazepine; Dibenzazepines; Female; Humans; Middle Aged

1968
Carbamazepine (Tegretol).
    The Medical letter on drugs and therapeutics, 1968, Jun-28, Volume: 10, Issue:13

    Topics: Agranulocytosis; Anemia, Aplastic; Blood Platelet Disorders; Carbamazepine; Dibenzazepines; Hematolo

1968
A case of aplastic anemia and pancytopenia with tegretol therapy.
    Headache, 1969, Volume: 9, Issue:1

    Topics: Anemia, Aplastic; Carbamazepine; Chemical and Drug Induced Liver Injury; Dibenzazepines; Humans; Mal

1969