Page last updated: 2024-10-24

carbamazepine and Alloxan Diabetes

carbamazepine has been researched along with Alloxan Diabetes in 3 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Research Excerpts

ExcerptRelevanceReference
" Analysis of the log dose-response curves for oxcarbazepine or gabapentin in a presence of amitriptyline and oxcarbazepine or gabapentin applied alone, revealed a synergism in oxcarbazepine-amitriptyline and additivity in gabapentin-amitriptyline combination."1.36Analysis of the antinociceptive interactions in two-drug combinations of gabapentin, oxcarbazepine and amitriptyline in streptozotocin-induced diabetic mice. ( Bosković, B; Micov, AM; Prostran, MS; Stepanović-Petrović, RM; Tomić, MA; Ugresić, ND; Vucković, SM, 2010)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
El-Sherbeeny, NA1
Ibrahiem, AT1
Ali, HS1
Farag, NE1
Toraih, EA1
Zaitone, SA1
Tomić, MA1
Vucković, SM1
Stepanović-Petrović, RM1
Micov, AM1
Ugresić, ND1
Prostran, MS1
Bosković, B1
Ardid, D1
Lamberty, Y1
Alloui, A1
Coudore-Civiale, MA1
Klitgaard, H1
Eschalier, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Placebo-Controlled Crossover Trial of Levetiracetam on Ethanol Intake[NCT01168687]46 participants (Actual)Interventional2008-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Standard Alcoholic Drinks Per Treatment Period

The primary outcome of this study is to determine the effect of levetiracetam on alcohol consumption as measured by change in # of drinks during each treatment period. (NCT01168687)
Timeframe: During each 14 day treatment period

Interventionnumber of drinks per treatment period (Mean)
All Subjects (n = 46) Placebo41.2
All Subjects (n = 46) Levetiracetam45.4

Other Studies

3 other studies available for carbamazepine and Alloxan Diabetes

ArticleYear
Carbamazepine conquers spinal GAP43 deficiency and sciatic Nav1.5 upregulation in diabetic mice: novel mechanisms in alleviating allodynia and hyperalgesia.
    Archives of pharmacal research, 2020, Volume: 43, Issue:7

    Topics: Alloxan; Animals; Carbamazepine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Mod

2020
Analysis of the antinociceptive interactions in two-drug combinations of gabapentin, oxcarbazepine and amitriptyline in streptozotocin-induced diabetic mice.
    European journal of pharmacology, 2010, Feb-25, Volume: 628, Issue:1-3

    Topics: Administration, Oral; Amines; Amitriptyline; Analgesics; Animals; Behavior, Animal; Carbamazepine; C

2010
Antihyperalgesic effect of levetiracetam in neuropathic pain models in rats.
    European journal of pharmacology, 2003, Jul-18, Volume: 473, Issue:1

    Topics: Acute Disease; Analgesics; Animals; Carbamazepine; Chronic Disease; Constriction, Pathologic; Diabet

2003