carbamazepine has been researched along with Allodynia in 38 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The synergistic interaction between paracetamol and oxcarbazepine provides new information about combination pain treatment and should be explored further in patients, especially with somatic and/or visceral pain." | 7.76 | Synergistic interactions between paracetamol and oxcarbazepine in somatic and visceral pain models in rodents. ( Bosković, B; Prostran, MS; Stepanović-Petrović, RM; Tomić, MA; Ugresić, ND; Vucković, SM, 2010) |
| "We studied whether peripheral alpha2-adrenergic receptors are involved in the antihyperalgesic effects of oxcarbazepine by examining the effects of yohimbine (selective alpha2-adrenoceptor antagonist), BRL 44408 (selective alpha(2A)-adrenoceptor antagonist), MK-912 (selective alpha2C-adrenoceptor antagonist), and clonidine (alpha2-adrenoceptor agonist) on the antihyperalgesic effect of oxcarbazepine in the rat model of inflammatory pain." | 7.74 | The involvement of peripheral alpha 2-adrenoceptors in the antihyperalgesic effect of oxcarbazepine in a rat model of inflammatory pain. ( Bosković, B; Paranos, SLj; Prostran, MS; Stepanović-Petrović, RM; Tomić, MA; Ugresić, ND; Vucković, SM, 2007) |
| "Facial allodynia was assessed using von Frey test." | 5.56 | LOW-DOSE NALTREXONE REVERSES FACIAL MECHANICAL ALLODYNIA IN A RAT MODEL OF TRIGEMINAL NEURALGIA. ( da Silva Torres, IL; de Oliveira, CL; de Oliveira, FF; de Souza, A; de Souza, VS; Lopes, BC; Marques, LX; Medeiros, LF, 2020) |
| "Treatment with carbamazepine provided significant analgesic relief in terms of both the frequency and intensity of pain." | 5.38 | A new variant nummular headache: large diameter accompanied with bitrigeminal hyperalgesia and successful treatment with carbamazepine. ( Li, LS; Man, YH; Mao, XJ; Wu, J; Yao, G; Yu, TM, 2012) |
| "The synergistic interaction between paracetamol and oxcarbazepine provides new information about combination pain treatment and should be explored further in patients, especially with somatic and/or visceral pain." | 3.76 | Synergistic interactions between paracetamol and oxcarbazepine in somatic and visceral pain models in rodents. ( Bosković, B; Prostran, MS; Stepanović-Petrović, RM; Tomić, MA; Ugresić, ND; Vucković, SM, 2010) |
| "We studied whether peripheral alpha2-adrenergic receptors are involved in the antihyperalgesic effects of oxcarbazepine by examining the effects of yohimbine (selective alpha2-adrenoceptor antagonist), BRL 44408 (selective alpha(2A)-adrenoceptor antagonist), MK-912 (selective alpha2C-adrenoceptor antagonist), and clonidine (alpha2-adrenoceptor agonist) on the antihyperalgesic effect of oxcarbazepine in the rat model of inflammatory pain." | 3.74 | The involvement of peripheral alpha 2-adrenoceptors in the antihyperalgesic effect of oxcarbazepine in a rat model of inflammatory pain. ( Bosković, B; Paranos, SLj; Prostran, MS; Stepanović-Petrović, RM; Tomić, MA; Ugresić, ND; Vucković, SM, 2007) |
| " Oxcarbazepine and carbamazepine (3-100 mg x kg(-1)) did not affect mechanical hyperalgesia or tactile allodynia induced by partial sciatic nerve ligation in the rat following oral administration." | 3.72 | Comparative activity of the anti-convulsants oxcarbazepine, carbamazepine, lamotrigine and gabapentin in a model of neuropathic pain in the rat and guinea-pig. ( Bevan, S; Fox, A; Gentry, C; Kesingland, A; Patel, S, 2003) |
| "The results showed that CCI-ION induced hyperalgesia, which was attenuated by lidocaine or carbamazepine, developed anxiety-like behavior, which was reduced only by midazolam, and displayed a reduced number of 50-kHz calls, compared to sham." | 1.72 | Trigeminal neuropathic pain reduces 50-kHz ultrasonic vocalizations in rats, which are restored by analgesic drugs. ( Araya, EI; Baggio, DF; Chichorro, JG; Koren, LO; Schwarting, RKW, 2022) |
| "Trigeminal neuralgia is unilateral, lancinating, episodic pain that can be provoked by routine activities." | 1.72 | Analgesic Effect of Tranilast in an Animal Model of Neuropathic Pain and Its Role in the Regulation of Tetrahydrobiopterin Synthesis. ( Ikutame, D; Iwasa, T; Matsuka, Y; Okura, K; Oshima, M; Raju, R; Raman, S; Waskitho, A, 2022) |
| "Facial allodynia was assessed using von Frey test." | 1.56 | LOW-DOSE NALTREXONE REVERSES FACIAL MECHANICAL ALLODYNIA IN A RAT MODEL OF TRIGEMINAL NEURALGIA. ( da Silva Torres, IL; de Oliveira, CL; de Oliveira, FF; de Souza, A; de Souza, VS; Lopes, BC; Marques, LX; Medeiros, LF, 2020) |
| "This formulation reduced systemic exposure to carbamazepine over 1,000-fold relative to traditional analgesic dosing regimens." | 1.48 | Opiate-Free Pain Therapy Using Carbamazepine-Loaded Microparticles Provides Up to 2 Weeks of Pain Relief in a Neuropathic Pain Model. ( Dai, H; Doherty, C; Gulati, A; Holzhaus, K; Khalil, A; Mehta, N; Mercedes, G; Reynolds, FM; Tilley, DM, 2018) |
| "The development of hind paw mechanical allodynia was measured after BCAO using the von Frey test." | 1.43 | Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia. ( Harada, S; Matsuura, W; Tokuyama, S, 2016) |
| "The selected neuropathic pain model was the spared nerve injury (SNI) model and the endpoints were burrowing and measures of paw posture in Sprague Dawley rats." | 1.39 | A back translation of pregabalin and carbamazepine against evoked and non-evoked endpoints in the rat spared nerve injury model of neuropathic pain. ( de Lannoy, IA; Dykstra, C; Higgins, GA; Lau, W; Lee, DK; Silenieks, LB; Thevarkunnel, S, 2013) |
| "As carbamazepine has shown antinociceptive properties in a variety of experimental and clinical settings, in the present study, we evaluated its potential antiallodynic effects on postoperative pain in naïve and morphine-dependent rats." | 1.38 | Carbamazepine potentiates morphine analgesia on postoperative pain in morphine-dependent rats. ( Moini Zanjani, T; Naseri, K; Sabetkasaei, M; Saghaei, E, 2012) |
| "Treatment with carbamazepine provided significant analgesic relief in terms of both the frequency and intensity of pain." | 1.38 | A new variant nummular headache: large diameter accompanied with bitrigeminal hyperalgesia and successful treatment with carbamazepine. ( Li, LS; Man, YH; Mao, XJ; Wu, J; Yao, G; Yu, TM, 2012) |
| "The percentage allodynia relief was only 60% for carbamazepine and 80% for pregabalin by single administration, whereas their co-administration relieved allodynia by 100%." | 1.38 | Combined carbamazepine and pregabalin therapy in a rat model of neuropathic pain. ( Ahn, HJ; Choi, SJ; Gwak, MS; Hahm, TS; Kim, JK; Ryu, S; Yu, JM, 2012) |
| "Neuropathic pain is a chronic pain condition that occurs and persists in a heterogeneous group of etiologically different diseases characterized by a primary lesion or dysfunction of the peripheral or central nervous system." | 1.37 | Discovery of molecules for the treatment of neuropathic pain: synthesis, antiallodynic and antihyperalgesic activities of 5-(4-nitrophenyl)furoic-2-acid hydrazones. ( Arjun, M; Menon, N; Semwal, A; Sriram, D; Yogeeswari, P, 2011) |
| "Air-puff thresholds (mechanical allodynia), pin prick responses (mechanical hyperalgesia), and spontaneous scratching behavior were examined 3 days before surgery and at 3, 7, 10, 14, 17, 21, 24, 30, and 40 days after surgery." | 1.35 | Compression of the trigeminal ganglion produces prolonged nociceptive behavior in rats. ( Ahn, DK; Bae, YC; Han, SR; Ju, JS; Kim, BC; Lee, MK; Lim, EJ; Yang, GY, 2009) |
| "Oral carbamazepine was partially effective to ameliorate the intractable central poststroke pain." | 1.35 | [Hyperalgesia with loss of temperature sensation in one side of the body due to pinpoint infarction of contralateral spinothalamic tract]. ( Kanda, T; Kashiwamura, Y; Kawai, M; Koga, M; Negoro, K; Ogasawara, J, 2009) |
| "Bicuculline alone did not produce an intrinsic effect in the paw-pressure test." | 1.35 | GABAergic mechanisms are involved in the antihyperalgesic effects of carbamazepine and oxcarbazepine in a rat model of inflammatory hyperalgesia. ( Bosković, B; Kocev, N; Prostran, MS; Stepanović-Petrović, RM; Tomić, MA; Ugresić, ND; Vucković, SM, 2008) |
| "Significant allodynia and hyperalgesia to cold stimuli were rapidly observed from 24 h to day 5 with a maximum lowering of 76% at t+30 h versus control." | 1.34 | Behavioral and immunohistological assessment of painful neuropathy induced by a single oxaliplatin injection in the rat. ( Authier, N; Balayssac, D; Coudoré, F; Coudoré-Civiale, MA; Eschalier, A; Ling, B, 2007) |
| "Gabapentin has been shown to be useful in treatment of different conditions which may be caused by increased neuronal excitability." | 1.32 | Treatment of chronic neuropathic pain after traumatic central cervical cord lesion with gabapentin. ( Haller, H; Leblhuber, F; Schmidhammer, R; Trenkler, J, 2003) |
| " Hill slope coefficients for the tested anticonvulsants indicate that the dose-response curve was less steep for gabapentin than for phenytoin, carbamazepine and ethosuximide." | 1.32 | Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats. ( Jevtovic-Todorovic, V; Rastogi, AJ; Todorovic, SM, 2003) |
| "Carbamazepine (100 mg/kg) was weakly effective against all the responses." | 1.31 | Evaluation of selective NK(1) receptor antagonist CI-1021 in animal models of inflammatory and neuropathic pain. ( Field, MJ; Gonzalez, MI; Hughes, J; Singh, L, 2000) |
| "Morphine pre-treatment was less effective in preventing development of hyperalgesia; however, whilst the ipsilateral (146 +/- 18 g) paw withdrawal threshold tended to be lower than the contralateral (183 +/- 8 g), this was not significant." | 1.29 | Pre-emptive administration of clonidine prevents development of hyperalgesia to mechanical stimuli in a model of mononeuropathy in the rat. ( Birch, PJ; Elliott, PJ; Harrison, SM; Smith, GD; Wiseman, J, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (5.26) | 18.2507 |
| 2000's | 19 (50.00) | 29.6817 |
| 2010's | 13 (34.21) | 24.3611 |
| 2020's | 4 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Yogeeswari, P | 2 |
| Ragavendran, JV | 1 |
| Sriram, D | 2 |
| Nageswari, Y | 1 |
| Kavya, R | 1 |
| Sreevatsan, N | 1 |
| Vanitha, K | 1 |
| Stables, J | 1 |
| Menon, N | 1 |
| Semwal, A | 1 |
| Arjun, M | 1 |
| Araya, EI | 1 |
| Baggio, DF | 1 |
| Koren, LO | 1 |
| Schwarting, RKW | 1 |
| Chichorro, JG | 3 |
| Raman, S | 1 |
| Waskitho, A | 1 |
| Raju, R | 1 |
| Iwasa, T | 1 |
| Ikutame, D | 1 |
| Okura, K | 1 |
| Oshima, M | 1 |
| Matsuka, Y | 1 |
| de Oliveira, CL | 1 |
| Medeiros, LF | 1 |
| de Souza, VS | 1 |
| Lopes, BC | 1 |
| de Oliveira, FF | 1 |
| Marques, LX | 1 |
| da Silva Torres, IL | 1 |
| de Souza, A | 1 |
| El-Sherbeeny, NA | 1 |
| Ibrahiem, AT | 1 |
| Ali, HS | 1 |
| Farag, NE | 1 |
| Toraih, EA | 1 |
| Zaitone, SA | 1 |
| Dai, H | 1 |
| Tilley, DM | 1 |
| Mercedes, G | 1 |
| Doherty, C | 1 |
| Gulati, A | 1 |
| Mehta, N | 1 |
| Khalil, A | 1 |
| Holzhaus, K | 1 |
| Reynolds, FM | 1 |
| Lau, W | 1 |
| Dykstra, C | 1 |
| Thevarkunnel, S | 1 |
| Silenieks, LB | 1 |
| de Lannoy, IA | 1 |
| Lee, DK | 1 |
| Higgins, GA | 1 |
| Bektas, N | 1 |
| Arslan, R | 1 |
| Ozturk, Y | 1 |
| Kopruszinski, CM | 2 |
| Reis, RC | 2 |
| Bressan, E | 1 |
| Reeh, PW | 1 |
| Ren, Z | 1 |
| Yang, B | 2 |
| Shi, L | 1 |
| Sun, QL | 1 |
| Sun, AP | 1 |
| Lu, L | 1 |
| Liu, X | 1 |
| Zhao, R | 1 |
| Zhai, S | 1 |
| Matsuura, W | 1 |
| Harada, S | 1 |
| Tokuyama, S | 1 |
| Ahn, DK | 1 |
| Lim, EJ | 1 |
| Kim, BC | 1 |
| Yang, GY | 1 |
| Lee, MK | 1 |
| Ju, JS | 1 |
| Han, SR | 1 |
| Bae, YC | 1 |
| Kashiwamura, Y | 1 |
| Kawai, M | 1 |
| Ogasawara, J | 1 |
| Koga, M | 1 |
| Negoro, K | 1 |
| Kanda, T | 1 |
| Tomić, MA | 8 |
| Vucković, SM | 8 |
| Stepanović-Petrović, RM | 8 |
| Ugresić, ND | 5 |
| Prostran, MS | 8 |
| Bosković, B | 10 |
| Poznanović, G | 1 |
| Naseri, K | 1 |
| Sabetkasaei, M | 1 |
| Moini Zanjani, T | 1 |
| Saghaei, E | 1 |
| Man, YH | 1 |
| Yu, TM | 1 |
| Li, LS | 1 |
| Yao, G | 1 |
| Mao, XJ | 1 |
| Wu, J | 1 |
| Hahm, TS | 1 |
| Ahn, HJ | 1 |
| Ryu, S | 1 |
| Gwak, MS | 1 |
| Choi, SJ | 1 |
| Kim, JK | 1 |
| Yu, JM | 1 |
| Walker, KM | 1 |
| Urban, L | 1 |
| Medhurst, SJ | 1 |
| Patel, S | 2 |
| Panesar, M | 1 |
| Fox, AJ | 1 |
| McIntyre, P | 1 |
| Ardid, D | 1 |
| Lamberty, Y | 1 |
| Alloui, A | 1 |
| Coudore-Civiale, MA | 2 |
| Klitgaard, H | 1 |
| Eschalier, A | 2 |
| Haller, H | 1 |
| Leblhuber, F | 1 |
| Trenkler, J | 1 |
| Schmidhammer, R | 1 |
| Todorovic, SM | 1 |
| Rastogi, AJ | 1 |
| Jevtovic-Todorovic, V | 1 |
| Fox, A | 1 |
| Gentry, C | 1 |
| Kesingland, A | 1 |
| Bevan, S | 1 |
| Ugrešić, N | 5 |
| Vuckovic, S | 2 |
| Tomic, M | 2 |
| Stepanovic-Petrovic, R | 2 |
| Prostran, M | 2 |
| Ilyin, VI | 1 |
| Pomonis, JD | 1 |
| Whiteside, GT | 1 |
| Harrison, JE | 1 |
| Pearson, MS | 1 |
| Mark, L | 1 |
| Turchin, PI | 1 |
| Gottshall, S | 1 |
| Carter, RB | 1 |
| Nguyen, P | 1 |
| Hogenkamp, DJ | 1 |
| Olanrewaju, S | 1 |
| Benjamin, E | 1 |
| Woodward, RM | 1 |
| Ling, B | 1 |
| Balayssac, D | 1 |
| Coudoré, F | 1 |
| Authier, N | 1 |
| Paranos, SLj | 1 |
| Kocev, N | 1 |
| Smith, GD | 1 |
| Harrison, SM | 1 |
| Wiseman, J | 1 |
| Elliott, PJ | 1 |
| Birch, PJ | 1 |
| Bianchi, M | 1 |
| Rossoni, G | 1 |
| Sacerdote, P | 1 |
| Panerai, AE | 1 |
| Berti, F | 1 |
| Gonzalez, MI | 1 |
| Field, MJ | 1 |
| Hughes, J | 1 |
| Singh, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Placebo-Controlled Crossover Trial of Levetiracetam on Ethanol Intake[NCT01168687] | 46 participants (Actual) | Interventional | 2008-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The primary outcome of this study is to determine the effect of levetiracetam on alcohol consumption as measured by change in # of drinks during each treatment period. (NCT01168687)
Timeframe: During each 14 day treatment period
| Intervention | number of drinks per treatment period (Mean) |
|---|---|
| All Subjects (n = 46) Placebo | 41.2 |
| All Subjects (n = 46) Levetiracetam | 45.4 |
38 other studies available for carbamazepine and Allodynia
| Article | Year |
|---|---|
Discovery of 4-aminobutyric acid derivatives possessing anticonvulsant and antinociceptive activities: a hybrid pharmacophore approach.
Topics: Analgesics; Animals; Anticonvulsants; Disease Models, Animal; gamma-Aminobutyric Acid; Hyperalgesia; | 2007 |
Discovery of molecules for the treatment of neuropathic pain: synthesis, antiallodynic and antihyperalgesic activities of 5-(4-nitrophenyl)furoic-2-acid hydrazones.
Topics: Analgesics; Animals; Disease Models, Animal; Drug Discovery; Female; Furans; Humans; Hydrazones; Hyp | 2011 |
Trigeminal neuropathic pain reduces 50-kHz ultrasonic vocalizations in rats, which are restored by analgesic drugs.
Topics: Analgesics; Animals; Carbamazepine; Hyperalgesia; Lidocaine; Male; Midazolam; Neuralgia; Rats; Trige | 2022 |
Analgesic Effect of Tranilast in an Animal Model of Neuropathic Pain and Its Role in the Regulation of Tetrahydrobiopterin Synthesis.
Topics: Analgesics; Animals; Biopterins; Carbamazepine; Disease Models, Animal; Hyperalgesia; Neuralgia; ort | 2022 |
LOW-DOSE NALTREXONE REVERSES FACIAL MECHANICAL ALLODYNIA IN A RAT MODEL OF TRIGEMINAL NEURALGIA.
Topics: Analgesics, Non-Narcotic; Animals; Brain-Derived Neurotrophic Factor; Carbamazepine; Disease Models, | 2020 |
Carbamazepine conquers spinal GAP43 deficiency and sciatic Nav1.5 upregulation in diabetic mice: novel mechanisms in alleviating allodynia and hyperalgesia.
Topics: Alloxan; Animals; Carbamazepine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Mod | 2020 |
Opiate-Free Pain Therapy Using Carbamazepine-Loaded Microparticles Provides Up to 2 Weeks of Pain Relief in a Neuropathic Pain Model.
Topics: Analgesics; Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Dosage Forms; Hyperalge | 2018 |
A back translation of pregabalin and carbamazepine against evoked and non-evoked endpoints in the rat spared nerve injury model of neuropathic pain.
Topics: Animals; Behavior, Animal; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; | 2013 |
Zonisamide: Antihyperalgesic efficacy, the role of serotonergic receptors on efficacy in a rat model for painful diabetic neuropathy.
Topics: Animals; Anticonvulsants; Carbamazepine; Diabetic Neuropathies; Disease Models, Animal; Dose-Respons | 2014 |
Vitamin B complex attenuated heat hyperalgesia following infraorbital nerve constriction in rats and reduced capsaicin in vivo and in vitro effects.
Topics: Animals; Calcium; Capsaicin; Carbamazepine; Constriction; Dose-Response Relationship, Drug; Drug Syn | 2015 |
Carbamazepine Withdrawal-induced Hyperalgesia in Chronic Neuropathic Pain.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Carbamazepine; Chronic Pain; Drug Therapy, Combination | 2015 |
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antico | 2016 |
Compression of the trigeminal ganglion produces prolonged nociceptive behavior in rats.
Topics: Agar; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Body Weight; Carbamazepine; Facial Pain; | 2009 |
[Hyperalgesia with loss of temperature sensation in one side of the body due to pinpoint infarction of contralateral spinothalamic tract].
Topics: Administration, Oral; Aged; Carbamazepine; Humans; Hyperalgesia; Infarction; Lateral Medullary Syndr | 2009 |
Synergistic interactions between paracetamol and oxcarbazepine in somatic and visceral pain models in rodents.
Topics: Acetaminophen; Acetic Acid; Algorithms; Analgesics, Non-Narcotic; Animals; Anticonvulsants; Carbamaz | 2010 |
Pharmacological interaction between oxcarbazepine and two COX inhibitors in a rat model of inflammatory hyperalgesia.
Topics: Animals; Carbamazepine; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug Interactions; Hype | 2011 |
Carbamazepine potentiates morphine analgesia on postoperative pain in morphine-dependent rats.
Topics: Analgesics; Animals; Ataxia; Carbamazepine; Drug Synergism; Hyperalgesia; Hypnotics and Sedatives; M | 2012 |
A new variant nummular headache: large diameter accompanied with bitrigeminal hyperalgesia and successful treatment with carbamazepine.
Topics: Analgesics, Non-Narcotic; Carbamazepine; Carotid Stenosis; Headache; Humans; Hyperalgesia; Male; Mid | 2012 |
Combined carbamazepine and pregabalin therapy in a rat model of neuropathic pain.
Topics: Analgesics; Animals; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug S | 2012 |
B vitamins relieve neuropathic pain behaviors induced by infraorbital nerve constriction in rats.
Topics: Analysis of Variance; Animals; Carbamazepine; Hyperalgesia; Male; Nerve Compression Syndromes; Neura | 2012 |
The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain.
Topics: Algorithms; Animals; Anticonvulsants; Capsaicin; Carbamazepine; Dose-Response Relationship, Drug; Gu | 2003 |
Antihyperalgesic effect of levetiracetam in neuropathic pain models in rats.
Topics: Acute Disease; Analgesics; Animals; Carbamazepine; Chronic Disease; Constriction, Pathologic; Diabet | 2003 |
Treatment of chronic neuropathic pain after traumatic central cervical cord lesion with gabapentin.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Arm; Carbamazepine; Central Cord Syndrome; Cervical Ver | 2003 |
Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Cyc | 2003 |
Comparative activity of the anti-convulsants oxcarbazepine, carbamazepine, lamotrigine and gabapentin in a model of neuropathic pain in the rat and guinea-pig.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Gabapentin; | 2003 |
The anti-hyperalgesic effects of carbamazepine and oxcarbazepine are attenuated by treatment with adenosine receptor antagonists.
Topics: Analgesics, Non-Narcotic; Animals; Caffeine; Carbamazepine; Dose-Response Relationship, Drug; Drug I | 2004 |
Peripheral antinociception by carbamazepine in an inflammatory mechanical hyperalgesia model in the rat: a new target for carbamazepine?
Topics: Analgesics; Animals; Caffeine; Carbamazepine; Concanavalin A; Disease Models, Animal; Dose-Response | 2006 |
Pharmacology of 2-[4-(4-chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide: a potent, broad-spectrum state-dependent sodium channel blocker for treating pain states.
Topics: Animals; Carbamazepine; Humans; Hyperalgesia; Lamotrigine; Male; Motor Activity; Pain; Pyrimidines; | 2006 |
The effects of alpha2-adrenoceptor agents on anti-hyperalgesic effects of carbamazepine and oxcarbazepine in a rat model of inflammatory pain.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics, Non-Narco | 2006 |
Peripheral anti-hyperalgesia by oxcarbazepine: involvement of adenosine A1 receptors.
Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Anticonvulsants; Caffein | 2006 |
Behavioral and immunohistological assessment of painful neuropathy induced by a single oxaliplatin injection in the rat.
Topics: Analgesics, Non-Narcotic; Animals; Antineoplastic Agents; Behavior, Animal; Calcitonin Gene-Related | 2007 |
Opioidergic mechanisms are not involved in the antihyperalgesic effects of carbamazepine and oxcarbazepine.
Topics: Analgesics, Non-Narcotic; Animals; Anticonvulsants; Carbamazepine; Concanavalin A; Hyperalgesia; Mal | 2007 |
The involvement of peripheral alpha 2-adrenoceptors in the antihyperalgesic effect of oxcarbazepine in a rat model of inflammatory pain.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Carbamazepine; Clonidine; Disease Models, Animal; Dos | 2007 |
Role of alpha2-adrenoceptors in the local peripheral antinociception by carbamazepine in a rat model of inflammatory mechanical hyperalgesia.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Ani | 2007 |
GABAergic mechanisms are involved in the antihyperalgesic effects of carbamazepine and oxcarbazepine in a rat model of inflammatory hyperalgesia.
Topics: Analgesics, Non-Narcotic; Animals; Anticonvulsants; Bicuculline; Carbamazepine; Concanavalin A; Dise | 2008 |
Pre-emptive administration of clonidine prevents development of hyperalgesia to mechanical stimuli in a model of mononeuropathy in the rat.
Topics: Analysis of Variance; Animals; Baclofen; Carbamazepine; Clonidine; Disease Models, Animal; Hyperalge | 1993 |
Carbamazepine exerts anti-inflammatory effects in the rat.
Topics: Animals; Anti-Inflammatory Agents; Carbamazepine; Dinoprostone; Dose-Response Relationship, Drug; Ed | 1995 |
Evaluation of selective NK(1) receptor antagonist CI-1021 in animal models of inflammatory and neuropathic pain.
Topics: Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Benzofurans; Ca | 2000 |