Page last updated: 2024-10-24

carbamazepine and Alexander Disease

carbamazepine has been researched along with Alexander Disease in 1 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Alexander Disease: Rare leukoencephalopathy with infantile-onset accumulation of Rosenthal fibers in the subpial, periventricular, and subependymal zones of the brain. Rosenthal fibers are GLIAL FIBRILLARY ACIDIC PROTEIN aggregates found in ASTROCYTES. Juvenile- and adult-onset types show progressive atrophy of the lower brainstem instead. De novo mutations in the GFAP gene are associated with the disease with propensity for paternal inheritance.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khanlou, N1
Mathern, GW1
Mitchell, WG1
Salamon, N1
Pope, WB1
Yong, WH1
Vinters, HV1

Other Studies

1 other study available for carbamazepine and Alexander Disease

ArticleYear
Cortical dysplasia with prominent Rosenthal fiber formation in a case of intractable pediatric epilepsy.
    Human pathology, 2009, Volume: 40, Issue:8

    Topics: Alexander Disease; Anticonvulsants; Brain; Carbamazepine; Cerebral Cortex; Child, Preschool; Diagnos

2009