Page last updated: 2024-10-24

carbamazepine and Age-Related Osteoporosis

carbamazepine has been researched along with Age-Related Osteoporosis in 8 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Research Excerpts

ExcerptRelevanceReference
"To study the markers of bone turnover in epilepsy patients in the different stages of the pubertal growth before and after the beginning of carbamazepine (CBZ) monotherapy."3.71Increased bone turnover in prepubertal, pubertal, and postpubertal patients receiving carbamazepine. ( Chiarelli, F; Greco, R; Latini, G; Morgese, G; Verrotti, A, 2002)
"Axial (second, third, and fourth lumbar vertebrae) and appendicular (distal third of radius) bone mineral density was measured by dual-energy x-ray absorptiometry in 27 healthy children and 26 children with uncomplicated idiopathic epilepsy treated with either carbamazepine (n = 13) or valproate (n = 13) for more than 18 months."3.69Effect of carbamazepine and valproate on bone mineral density. ( Bodensteiner, JB; Hobbs, GR; Jacob, JC; Penney, S; Riggs, JE; Sheth, RD; Wesolowski, CA, 1995)
"For patients with mental retardation or developmental delay, 25(OH)D3 levels were lower than the levels in patients with normal intelligence quotient levels (p=0."1.40Vitamin D levels in children and adolescents with antiepileptic drug treatment. ( Baek, JH; Eun, BL; Kim, GH; Kim, MK; Seo, YH, 2014)
"Markers of bone formation and bone resorption were determined in serum and urine."1.31Long-term anticonvulsant therapy leads to low bone mineral density--evidence for direct drug effects of phenytoin and carbamazepine on human osteoblast-like cells. ( Becker, A; Feldkamp, J; Scharff, D; Scherbaum, WA; Witte, OW, 2000)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Wang, H1
Liu, Z1
Niu, D1
Li, H1
Han, Y1
Peng, J1
Qian, Q1
Zhang, R1
Yang, M1
Li, Y1
Liu, H1
Ren, M1
Tao, ZS1
Baek, JH1
Seo, YH1
Kim, GH1
Kim, MK1
Eun, BL1
Sheth, RD2
Verrotti, A1
Greco, R1
Latini, G1
Morgese, G1
Chiarelli, F1
Baars, A1
Baars, M1
Beier, R1
Bretschneider, T1
Wesolowski, CA1
Jacob, JC1
Penney, S1
Hobbs, GR1
Riggs, JE1
Bodensteiner, JB1
Feldkamp, J1
Becker, A1
Witte, OW1
Scharff, D1
Scherbaum, WA1

Other Studies

8 other studies available for carbamazepine and Age-Related Osteoporosis

ArticleYear
Carbamazepine regulates USP10 through miR-20a-5p to affect the deubiquitination of SKP2 and inhibit osteogenic differentiation.
    Journal of orthopaedic surgery and research, 2023, Nov-01, Volume: 18, Issue:1

    Topics: Alkaline Phosphatase; Carbamazepine; Cell Differentiation; Cells, Cultured; Collagen; Core Binding F

2023
Effect of alendronate on the femoral metaphyseal defect under carbamazepine in ovariectomized rats.
    Journal of orthopaedic surgery and research, 2021, Jan-06, Volume: 16, Issue:1

    Topics: Alendronate; Animals; Anticonvulsants; Bone Density Conservation Agents; Bone Regeneration; Carbamaz

2021
Vitamin D levels in children and adolescents with antiepileptic drug treatment.
    Yonsei medical journal, 2014, Volume: 55, Issue:2

    Topics: Adolescent; Anticonvulsants; Bone Density; Bone Diseases, Metabolic; Carbamazepine; Child; Child, Pr

2014
Bone health in epilepsy.
    Epilepsia, 2002, Volume: 43, Issue:12

    Topics: Adolescent; Anticonvulsants; Bone Diseases, Metabolic; Carbamazepine; Cytochrome P-450 Enzyme System

2002
Increased bone turnover in prepubertal, pubertal, and postpubertal patients receiving carbamazepine.
    Epilepsia, 2002, Volume: 43, Issue:12

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Biomarkers; Bone Diseases, Metabolic; Bone Resorpti

2002
[Diagnosis of osteopathy caused by antiepileptic drugs].
    Zeitschrift fur arztliche Fortbildung, 1981, Aug-01, Volume: 75, Issue:15

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Bone Diseases; Carbamazepine; Epilepsy; Female; Femur; Han

1981
Effect of carbamazepine and valproate on bone mineral density.
    The Journal of pediatrics, 1995, Volume: 127, Issue:2

    Topics: Absorptiometry, Photon; Adolescent; Bone Density; Calcium, Dietary; Carbamazepine; Case-Control Stud

1995
Long-term anticonvulsant therapy leads to low bone mineral density--evidence for direct drug effects of phenytoin and carbamazepine on human osteoblast-like cells.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2000, Volume: 108, Issue:1

    Topics: Absorptiometry, Photon; Adult; Amino Acids; Anticonvulsants; Bone Density; Bone Resorption; Carbamaz

2000