carbamazepine has been researched along with Age-Related Memory Disorders in 26 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate whether histidine can enhance the anticonvulsant efficacy of carbamazepine (CBZ) and simultaneously improve the spatial memory impairment induced by transauricular kindled seizures in Sprague-Dawley rats." | 7.73 | Histidine enhances carbamazepine action against seizures and improves spatial memory deficits induced by chronic transauricular kindling in rats. ( Chen, Z; Jin, CL; Li, Q; Liu, LY; Xu, LS; Yang, LX; Zhu-Ge, ZB, 2005) |
| " The aim of this study was to examine the frequency of the adverse events of antiepileptic drugs (AEDs), in particular carbamazepine (CBZ) and oxcarbazepine (OXC) in patients with neuralgiform pain using the psychometrically tested Liverpool Adverse Events Profile (AEP) and provide clinicians with guidance as to when to change management." | 5.42 | Comparison of tolerability and adverse symptoms in oxcarbazepine and carbamazepine in the treatment of trigeminal neuralgia and neuralgiform headaches using the Liverpool Adverse Events Profile (AEP). ( Besi, E; Boniface, DR; Cregg, R; Zakrzewska, JM, 2015) |
| " Memory alteration was least common with lamotrigine and oxcarbazepine, and there was less association between fatigues with oxcarbazepine/pregabalin." | 3.88 | Adverse effects of anti-epileptics in trigeminal neuralgiform pain. ( Cregg, R; Lee, G; O'Keeffe, AG; Reading, J; Tentolouris-Piperas, V; Zakrzewska, JM, 2018) |
| " We have tested the therapeutic potential of rapamycin, an inhibitor of the mammalian target of rapamycin (mTOR) and three other autophagy activators (spermidine, carbamazepine, and tamoxifen) in a FTLD-U mouse model with TDP-43 proteinopathies." | 3.78 | Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43. ( Guo, BS; Liu, YC; Shen, CK; Tsai, KJ; Wang, IF; Wu, CC; Yang, CH, 2012) |
| "To investigate whether histidine can enhance the anticonvulsant efficacy of carbamazepine (CBZ) and simultaneously improve the spatial memory impairment induced by transauricular kindled seizures in Sprague-Dawley rats." | 3.73 | Histidine enhances carbamazepine action against seizures and improves spatial memory deficits induced by chronic transauricular kindling in rats. ( Chen, Z; Jin, CL; Li, Q; Liu, LY; Xu, LS; Yang, LX; Zhu-Ge, ZB, 2005) |
| " The aim of this study was to examine the frequency of the adverse events of antiepileptic drugs (AEDs), in particular carbamazepine (CBZ) and oxcarbazepine (OXC) in patients with neuralgiform pain using the psychometrically tested Liverpool Adverse Events Profile (AEP) and provide clinicians with guidance as to when to change management." | 1.42 | Comparison of tolerability and adverse symptoms in oxcarbazepine and carbamazepine in the treatment of trigeminal neuralgia and neuralgiform headaches using the Liverpool Adverse Events Profile (AEP). ( Besi, E; Boniface, DR; Cregg, R; Zakrzewska, JM, 2015) |
| " Since rapamycin is also an immune suppressor, there is a concern that long-term use of rapamycin may bring severe unwanted side effects." | 1.39 | Autophagy enhancer carbamazepine alleviates memory deficits and cerebral amyloid-β pathology in a mouse model of Alzheimer's disease. ( Le, W; Li, L; Li, T; Liu, H; Tang, Y; Yang, W; Zhang, S; Zhang, X, 2013) |
| "Curcumin has shown antioxidant, anti-inflammatory and neuro-protective properties." | 1.36 | Curcumin ameliorates cognitive dysfunction and oxidative damage in phenobarbitone and carbamazepine administered rats. ( Gupta, YK; Mehla, J; Reeta, KH, 2010) |
| "In particular, memory deficits, attentional problems, psychomotor slowing and reading and writing difficulties are highlighted, and the impact of the seizures, brain damage, and anticonvulsant drugs on cognitive function noted." | 1.27 | [Cognitive effects of antiepileptic drugs]. ( Trimble, R, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (34.62) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 11 (42.31) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Valero, M | 1 |
| Averkin, RG | 1 |
| Fernandez-Lamo, I | 1 |
| Aguilar, J | 1 |
| Lopez-Pigozzi, D | 1 |
| Brotons-Mas, JR | 1 |
| Cid, E | 1 |
| Tamas, G | 1 |
| Menendez de la Prida, L | 1 |
| Tentolouris-Piperas, V | 1 |
| Lee, G | 1 |
| Reading, J | 1 |
| O'Keeffe, AG | 1 |
| Zakrzewska, JM | 2 |
| Cregg, R | 2 |
| Barton, S | 1 |
| Nadebaum, C | 1 |
| Anderson, VA | 1 |
| Vajda, F | 1 |
| Reutens, DC | 1 |
| Wood, AG | 1 |
| Cohen, MJ | 1 |
| Meador, KJ | 1 |
| May, R | 1 |
| Loblein, H | 1 |
| Conrad, T | 1 |
| Baker, GA | 1 |
| Bromley, RL | 1 |
| Clayton-Smith, J | 1 |
| Kalayjian, LA | 1 |
| Kanner, A | 1 |
| Liporace, JD | 1 |
| Pennell, PB | 1 |
| Privitera, M | 1 |
| Loring, DW | 1 |
| Besi, E | 1 |
| Boniface, DR | 1 |
| Reeta, KH | 1 |
| Mehla, J | 1 |
| Gupta, YK | 1 |
| Hessen, E | 1 |
| Lossius, MI | 1 |
| Gjerstad, L | 1 |
| Toledo, M | 1 |
| Munuera, J | 1 |
| Salas-Puig, X | 1 |
| Santamarina, E | 1 |
| Lacuey, N | 1 |
| Rovira, A | 1 |
| Wang, IF | 1 |
| Guo, BS | 1 |
| Liu, YC | 1 |
| Wu, CC | 1 |
| Yang, CH | 1 |
| Tsai, KJ | 1 |
| Shen, CK | 1 |
| Corradini, I | 1 |
| Donzelli, A | 1 |
| Antonucci, F | 1 |
| Welzl, H | 1 |
| Loos, M | 1 |
| Martucci, R | 1 |
| De Astis, S | 1 |
| Pattini, L | 1 |
| Inverardi, F | 1 |
| Wolfer, D | 1 |
| Caleo, M | 1 |
| Bozzi, Y | 1 |
| Verderio, C | 1 |
| Frassoni, C | 1 |
| Braida, D | 1 |
| Clerici, M | 1 |
| Lipp, HP | 1 |
| Sala, M | 1 |
| Matteoli, M | 1 |
| Li, L | 1 |
| Zhang, S | 1 |
| Zhang, X | 1 |
| Li, T | 1 |
| Tang, Y | 1 |
| Liu, H | 1 |
| Yang, W | 1 |
| Le, W | 1 |
| Li, Q | 1 |
| Jin, CL | 1 |
| Xu, LS | 1 |
| Zhu-Ge, ZB | 1 |
| Yang, LX | 1 |
| Liu, LY | 1 |
| Chen, Z | 1 |
| Mondadori, C | 1 |
| Schmutz, M | 1 |
| Baltzer, V | 1 |
| Butlin, AT | 2 |
| Danta, G | 2 |
| Cook, ML | 2 |
| Mellanby, J | 1 |
| Hawkins, C | 1 |
| Wilks, L | 1 |
| Andrewes, DG | 1 |
| Tomlinson, L | 1 |
| Elwes, RD | 1 |
| Reynolds, EH | 1 |
| Thompson, P | 1 |
| Huppert, F | 1 |
| Trimble, M | 1 |
| Pulliainen, V | 1 |
| Jokelainen, M | 1 |
| Wright, S | 1 |
| Young, AW | 1 |
| Hellawell, DJ | 1 |
| Aldenkamp, AP | 1 |
| Alpherts, WC | 1 |
| Blennow, G | 1 |
| Elmqvist, D | 1 |
| Heijbel, J | 1 |
| Nilsson, HL | 1 |
| Sandstedt, P | 1 |
| Tonnby, B | 1 |
| Wåhlander, L | 1 |
| Wosse, E | 1 |
| McCabe, PH | 1 |
| Eslinger, PJ | 1 |
| Wu, Y | 1 |
| Wang, L | 1 |
| Pedersen, B | 1 |
| Dam, M | 1 |
| Trimble, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Rapamycin (Sirolimus) Treatment for Amyotrophic Lateral Sclerosis[NCT03359538] | Phase 2 | 63 participants (Actual) | Interventional | 2017-09-19 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for carbamazepine and Age-Related Memory Disorders
| Article | Year |
|---|---|
Improvement in verbal memory after withdrawal of carbamazepine and valproate in patients with well-controlled epilepsy: a randomized, double-blind study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Double-Blind Method; Female; Humans; Male; | 2011 |
Effects of phenytoin and carbamazepine on cognitive functions in newly diagnosed epileptic patients.
Topics: Adult; Carbamazepine; Cognition Disorders; Epilepsy; Female; Follow-Up Studies; Humans; Learning; Ma | 1994 |
Withdrawal of antiepileptic medication in children--effects on cognitive function: The Multicenter Holmfrid Study.
Topics: Adolescent; Carbamazepine; Child; Cognition; Cognition Disorders; Epilepsy; Female; Follow-Up Studie | 1993 |
23 other studies available for carbamazepine and Age-Related Memory Disorders
| Article | Year |
|---|---|
Mechanisms for Selective Single-Cell Reactivation during Offline Sharp-Wave Ripples and Their Distortion by Fast Ripples.
Topics: Action Potentials; Animals; Anticonvulsants; Brain Waves; CA1 Region, Hippocampal; Carbamazepine; Di | 2017 |
Adverse effects of anti-epileptics in trigeminal neuralgiform pain.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cross-Sectional Studies; Fatigue; Female; Humans; Lamot | 2018 |
Memory dysfunction in school-aged children exposed prenatally to antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsy; Female; Hu | 2018 |
Fetal antiepileptic drug exposure and learning and memory functioning at 6 years of age: The NEAD prospective observational study.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Lamotrigine; Learning; Memor | 2019 |
Comparison of tolerability and adverse symptoms in oxcarbazepine and carbamazepine in the treatment of trigeminal neuralgia and neuralgiform headaches using the Liverpool Adverse Events Profile (AEP).
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Anticonvulsants; Carbamazepine; Cluster Headac | 2015 |
Curcumin ameliorates cognitive dysfunction and oxidative damage in phenobarbitone and carbamazepine administered rats.
Topics: Animals; Anticonvulsants; Antioxidants; Avoidance Learning; Brain; Carbamazepine; Cognition Disorder | 2010 |
Localisation value of ictal arterial spin-labelled sequences in partial seizures.
Topics: Adult; Anticonvulsants; Brain Injuries; Carbamazepine; Depressive Disorder; Diffusion Magnetic Reson | 2011 |
Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43.
Topics: Analysis of Variance; Animals; Autophagy; Blotting, Western; Carbamazepine; Caspase 3; Fluorometry; | 2012 |
Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs.
Topics: Animals; Anticonvulsants; Association Learning; Brain; Carbamazepine; Cognition Disorders; Epilepsy; | 2014 |
Autophagy enhancer carbamazepine alleviates memory deficits and cerebral amyloid-β pathology in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein | 2013 |
Histidine enhances carbamazepine action against seizures and improves spatial memory deficits induced by chronic transauricular kindling in rats.
Topics: Animals; Anticonvulsants; Brain; Brain Stem; Carbamazepine; Drug Synergism; Hippocampus; Histamine; | 2005 |
Potentiation of the anticonvulsant effects of antiepileptic drugs by "nootropics"; a potential new therapeutic approach.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Drug Synergis | 1984 |
Anticonvulsant effects on the memory performance of epileptics.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Intelligence; Memory; Memory Di | 1984 |
Anticonvulsants, folic acid and memory dysfunction in epileptics.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Erythrocytes; Folic Acid; Humans; Memor | 1984 |
The relationship between seizures and amnesia in experimental epilepsy.
Topics: Amnesia; Animals; Carbamazepine; Epilepsy; Humans; Male; Memory Disorders; Rats; Rats, Inbred Strain | 1984 |
The influence of carbamazepine and phenytoin on memory and other aspects of cognitive function in new referrals with epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Cognition Disorders; Decision Making; Epilepsy; Fixation, Oc | 1984 |
Anticonvulsant drugs, cognitive function and memory.
Topics: Anticonvulsants; Carbamazepine; Double-Blind Method; Epilepsy; Humans; Male; Memory Disorders; Menta | 1980 |
Sequential Cotard and Capgras delusions.
Topics: Adult; Brain; Capgras Syndrome; Carbamazepine; Chlorpromazine; Delusions; Depressive Disorder; Elect | 1993 |
Abnormal Wada and neuropsychological testing results due to topiramate therapy.
Topics: Amobarbital; Anticonvulsants; Carbamazepine; Carotid Artery, Internal; Drug Therapy, Combination; Ep | 2000 |
The effects of antiepileptic drugs on spatial learning and hippocampal protein kinase C gamma in immature rats.
Topics: Animals; Anticonvulsants; Blotting, Western; Carbamazepine; Hippocampus; Immunohistochemistry; Isoen | 2002 |
Memory disturbances in epileptic patients.
Topics: Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Memory Disorders; Phenytoin; Valproic Ac | 1986 |
[Cognitive effects of antiepileptic drugs].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cognition Disorders; Epilepsy; | 1987 |
American Academy of Pediatrics. Behavioral and cognitive effects of anticonvulsant therapy. Committee on Drugs.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Child; Child Behavior Disorders; Clonazepam; Cogni | 1985 |