Page last updated: 2024-10-24

carbamazepine and Affective Disorders

carbamazepine has been researched along with Affective Disorders in 96 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Research Excerpts

ExcerptRelevanceReference
"This study prospectively examined whether continued add-on treatment with oxcarbazepine (OXC) is associated with quantitative improvement in mood and anxiety symptoms in adult patients with partial epilepsy."9.12Oxcarbazepine improves mood in patients with epilepsy. ( Bria, P; Della Marca, G; Di Nicola, M; Janiri, L; Martinotti, G; Mazza, M; Mazza, S; Pozzi, G, 2007)
"Lamotrigine is used in pregnancy to control epilepsy and mood disorders."8.95Pregnancy Outcomes Following In Utero Exposure to Lamotrigine: A Systematic Review and Meta-Analysis. ( Adams-Webber, T; Barzilay, E; Leibson, T; Nulman, I; Pariente, G; Shulman, T, 2017)
" We review the clinical literature which suggests that tolerance can develop to most treatment approaches in bipolar illness and present an animal model of tolerance development to anticonvulsant effects of carbamazepine or lamotrigine on amgydala-kindled seizures."8.87Tolerance to the prophylactic effects of carbamazepine and related mood stabilizers in the treatment of bipolar disorders. ( Post, RM; Weiss, SR, 2011)
"Twenty-four patients suffering from affective disorders, who were being regularly treated with carbamazepine, were studied to determine the course of plasma levels of carbamazepine before (trough levels) and two and four hours after morning intake (peak levels)."7.67Measuring plasma levels of carbamazepine. A pharmacokinetic study in patients with affective disorders. ( Broekman, M; Jansen, GS; Nolen, WA, 1988)
" Since the effects of carbamazepine on substance P content are identical with previously described effects of lithium, an alteration in substance P neurotransmission may be one of the neurochemical bases of common clinical and behavioral effects of carbamazepine and lithium on affective disorders."7.67Effects of chronic treatment with trihexyphenidyl and carbamazepine alone or in combination with haloperidol on substance P content in rat brain: a possible implication of substance P in affective disorders. ( Mataga, N; Mitsushio, H; Takashima, M; Toru, M, 1988)
"A case of thrombocytopenia associated with carbamazepine use is reported, and previous reports of adverse hematologic effects in patients taking carbamazepine are discussed."7.67Thrombocytopenia associated with carbamazepine: case report and review. ( Baciewicz, G; Yerevanian, BI, 1984)
" According to the literature, OCBZ is regarded as effective in acute mania and appears to reduce the dosage of neuroleptics required for the treatment of affective and schizoaffective disorders."6.41Oxcarbazepine in affective and schizoaffective disorders. ( Dietrich, DE; Emrich, HM; Kropp, S, 2001)
"Affective disorders have a substantial public health impact due to morbidity, mortality, quality of life impairment and economic implications."6.41[Prophylactic long-term therapy of affective disorders with lithium, valproic acid and carbamazepine--effectiveness and cost-effectiveness]. ( Ahrens, B; Becker, T; Roick, C, 2001)
"Treatment with carbamazepine was evaluated in an open study design in 29 gerontopsychiatric inpatients."5.29[Therapeutic use of carbamazepine for treatment of agitation and affective disorders in geriatric psychiatry patients]. ( Lemke, MR; Stuhlmann, W, 1994)
"This study prospectively examined whether continued add-on treatment with oxcarbazepine (OXC) is associated with quantitative improvement in mood and anxiety symptoms in adult patients with partial epilepsy."5.12Oxcarbazepine improves mood in patients with epilepsy. ( Bria, P; Della Marca, G; Di Nicola, M; Janiri, L; Martinotti, G; Mazza, M; Mazza, S; Pozzi, G, 2007)
"Lamotrigine is used in pregnancy to control epilepsy and mood disorders."4.95Pregnancy Outcomes Following In Utero Exposure to Lamotrigine: A Systematic Review and Meta-Analysis. ( Adams-Webber, T; Barzilay, E; Leibson, T; Nulman, I; Pariente, G; Shulman, T, 2017)
" We review the clinical literature which suggests that tolerance can develop to most treatment approaches in bipolar illness and present an animal model of tolerance development to anticonvulsant effects of carbamazepine or lamotrigine on amgydala-kindled seizures."4.87Tolerance to the prophylactic effects of carbamazepine and related mood stabilizers in the treatment of bipolar disorders. ( Post, RM; Weiss, SR, 2011)
"A systematic search was carried out of electronic databases, reference books and other sources for original research studies which examined the effects of commonly used mood stabilizers (sodium valproate, carbamazepine, lamotrigine and lithium carbonate) on pregnancy outcomes."4.86Mood stabilizers in pregnancy: a systematic review. ( Buist, A; Galbally, M; Roberts, M, 2010)
" As the result of the detailed analysis of the literature the author recommends lamotrigine, carbamazepine and oxcarbazepine as first choice antiepileptic drug for epileptic patients suffering from depressive disorder, too."4.84[Effects of antiepileptic drugs on mood of people with epilepsy]. ( Rajna, P, 2007)
"Controlled studies of lithium, valproate and carbamazepine in preventing future episodes of affective disorders were classified according to methodological rigour, and meta-analyses were performed overall and on each type."4.80Mood stabilizers in the prevention of recurrent affective disorders: a meta-analysis. ( Davis, JM; Hogan, DM; Janicak, PG, 1999)
"In an attempt to find the key to reducing the excessive morbidity and mortality seen with mood disorders, our laboratory has been extensively investigating lithium's mechanisms of action in an integrated series of clinical and preclinical studies."4.80Modulation of CNS signal transduction pathways and gene expression by mood-stabilizing agents: therapeutic implications. ( Bebchuk, JM; Chen, G; Glitz, D; Hasanat, KA; Manji, HK; Moore, GJ, 1999)
" We describe the phenomenon of amygdala-kindled seizures episodically breaking through effective daily pharmacotherapy with carbamazepine and valproate, suggesting that these observations could reflect the balance of pathological vs compensatory illness-induced changes in gene expression."4.79A speculative model of affective illness cyclicity based on patterns of drug tolerance observed in amygdala-kindled seizures. ( Post, RM; Weiss, SR, 1996)
" Preclinical data are presented that another primary pathological process--the occurrence of kindled seizures--can evoke endogenous compensatory processes that are either anticonvulsant in their own right, or enable the anticonvulsant effects of a drug such as carbamazepine."4.78Ziskind-Somerfeld Research Award 1992. Endogenous biochemical abnormalities in affective illness: therapeutic versus pathogenic. ( Post, RM; Weiss, SR, 1992)
"Patients with major affective disorders are more likely to complete suicide than patients in any other medical group."3.79Anticonvulsant therapy and suicide risk in affective disorders. ( Goodwin, FK, 1999)
" Addition of carbamazepine to lithium can counteract lithium-induced subclinical hypothyroidism, possibly improving prophylactic efficacy in recurrent affective disorders."3.69Six-year follow-up of thyroid function during lithium treatment. ( Bocchetta, A; Cherchi, A; Del Zompo, M; Derai, R; Loviselli, A; Mossa, P; Velluzzi, F, 1996)
"Carbamazepine (CBZ) is known to have beneficial effects in the treatment of epilepsies and in the prophylaxis of affective disorders."3.68Calcium-antagonistic effects of carbamazepine in epilepsies and affective psychoses. ( Bingmann, D; Düsing, R; Grunze, H; Liu, Z; Mayer, A; Schirrmacher, K; Walden, J, 1993)
"This study surveyed serum level monitoring of lithium and carbamazepine in three psychiatric hospitals, to determine how the service is used with respect to affective disorders."3.68Serum drug level monitoring in affective disorders. ( Corner, DA; Krska, J, 1992)
" Since the effects of carbamazepine on substance P content are identical with previously described effects of lithium, an alteration in substance P neurotransmission may be one of the neurochemical bases of common clinical and behavioral effects of carbamazepine and lithium on affective disorders."3.67Effects of chronic treatment with trihexyphenidyl and carbamazepine alone or in combination with haloperidol on substance P content in rat brain: a possible implication of substance P in affective disorders. ( Mataga, N; Mitsushio, H; Takashima, M; Toru, M, 1988)
"A case of thrombocytopenia associated with carbamazepine use is reported, and previous reports of adverse hematologic effects in patients taking carbamazepine are discussed."3.67Thrombocytopenia associated with carbamazepine: case report and review. ( Baciewicz, G; Yerevanian, BI, 1984)
"The therapeutic effects of carbamazepine (CBZ) were evaluated in 103 patients with affective disorders, 54 with schizophrenic disorders, and 26 with schizoaffective disorders by a multi-institutional open study."3.67Clinical efficacy of carbamazepine in affective, schizoaffective, and schizophrenic disorders. ( Hazama, H; Inanaga, K; Itoh, H; Kurihara, M; Okuma, T; Otsuki, S; Sarai, K; Takahashi, R; Watanabe, S; Yamashita, I, 1989)
"Twenty-four patients suffering from affective disorders, who were being regularly treated with carbamazepine, were studied to determine the course of plasma levels of carbamazepine before (trough levels) and two and four hours after morning intake (peak levels)."3.67Measuring plasma levels of carbamazepine. A pharmacokinetic study in patients with affective disorders. ( Broekman, M; Jansen, GS; Nolen, WA, 1988)
"The English-language literature indexed on MEDLINE/PubMed was searched for original observational studies (controlled and uncontrolled, prospective and retrospective), case reports, and case series that evaluated or described pharmacokinetic changes or TDM during pregnancy or the postpartum period."2.50Pharmacotherapy for mood disorders in pregnancy: a review of pharmacokinetic changes and clinical recommendations for therapeutic drug monitoring. ( Byatt, N; Deligiannidis, KM; Freeman, MP, 2014)
"Agents introduced for the treatment of epilepsy have also been usedsimultaneously for psychiatric indications."2.43[Anticonvulsants treatment of psychiatric disorder in elderly patients]. ( Bidzan, L, 2006)
"Valproic acid (VPA) is an antiepileptic drug with mood-stabilizing properties."2.42Search for a common mechanism of mood stabilizers. ( Agam, G; Harwood, AJ, 2003)
"Affective disorders have a substantial public health impact due to morbidity, mortality, quality of life impairment and economic implications."2.41[Prophylactic long-term therapy of affective disorders with lithium, valproic acid and carbamazepine--effectiveness and cost-effectiveness]. ( Ahrens, B; Becker, T; Roick, C, 2001)
" According to the literature, OCBZ is regarded as effective in acute mania and appears to reduce the dosage of neuroleptics required for the treatment of affective and schizoaffective disorders."2.41Oxcarbazepine in affective and schizoaffective disorders. ( Dietrich, DE; Emrich, HM; Kropp, S, 2001)
" The newer anticonvulsants felbamate, lamotrigine, topiramate, and tiagabine have different hepatically-mediated drug-drug interactions, while the renally excreted gabapentin lacks hepatic drug-drug interactions but may have reduced bioavailability at higher doses."2.40Metabolism and excretion of mood stabilizers and new anticonvulsants. ( Corá-Locatelli, G; Frye, MA; Ketter, TA; Kimbrell, TA; Post, RM, 1999)
" A large number of neurotransmitters remain candidates for the psychotropic effects and a novel animal model requiring chronic administration of carbamazepine in order to show efficacy is reported (Weiss et al."2.38Sensitization and kindling perspectives for the course of affective illness: toward a new treatment with the anticonvulsant carbamazepine. ( Post, RM, 1990)
"Carbamazepine is a tricyclic compound structurally related to imipramine that has been used since the 1960's for the treatment of trigeminal neuralgias and then approved as an anticonvulsant in the U."2.37Carbamazepine in psychiatry: a review. ( Beaudry, P; Israel, M, 1988)
" Because dosage in general was moderate and serum levels were within therapeutic boundaries in most cases, the symptom seemed to have been caused by an interaction of drugs rather than by a single agent."1.29Asterixis induced by psychotropic drug treatment. ( Rittmannsberger, H, 1996)
"Treatment with carbamazepine was evaluated in an open study design in 29 gerontopsychiatric inpatients."1.29[Therapeutic use of carbamazepine for treatment of agitation and affective disorders in geriatric psychiatry patients]. ( Lemke, MR; Stuhlmann, W, 1994)

Research

Studies (96)

TimeframeStudies, this research(%)All Research%
pre-199028 (29.17)18.7374
1990's31 (32.29)18.2507
2000's25 (26.04)29.6817
2010's11 (11.46)24.3611
2020's1 (1.04)2.80

Authors

AuthorsStudies
Ho, AM1
Weinshilboum, RM1
Frye, MA2
Biernacka, JM1
Pariente, G1
Leibson, T1
Shulman, T1
Adams-Webber, T1
Barzilay, E1
Nulman, I1
Vilibić, M1
Jukić, V1
Vidović, A1
Brecić, P1
Deligiannidis, KM1
Byatt, N1
Freeman, MP1
Mauer, S1
Alahmari, R1
Vöhringer, PA1
Vergne, DE1
Lövdahl, H1
Correa, E1
Patkar, A1
Pae, C1
Strejilevich, S1
Dalley, S1
Ghaemi, SN1
Gorwood, P1
Richard-Devantoy, S1
Sentissi, O1
Le Strat, Y1
Olié, JP1
Pisanu, C1
Papadima, EM1
Del Zompo, M3
Squassina, A1
Sümegi, A1
Galbally, M1
Roberts, M1
Buist, A1
Post, RM13
Weiss, SR3
Gazdag, G1
Takács, R1
Ungvari, GS1
Tanahashi, S1
Yamamura, S1
Nakagawa, M1
Motomura, E1
Okada, M1
Hydzik, P1
Balicka-Slusarczyk, B1
Jastrzebski, M1
Brady, KT1
Sonne, SC1
Malcolm, RJ1
Randall, CL1
Dansky, BS1
Simpson, K1
Roberts, JS1
Brondino, M1
Scott, J1
Pope, M1
Dietrich, DE2
Kropp, S2
Emrich, HM3
Harwood, AJ1
Agam, G1
Harris, M1
Chandran, S1
Chakraborty, N1
Healy, D1
Kaufman, KR1
Gerner, R1
Himmerich, H1
Koethe, D1
Schuld, A1
Yassouridis, A1
Pollmächer, T1
Beresford, TP1
Arciniegas, D1
Clapp, L1
Martin, B1
Alfers, J1
Selai, C1
Bannister, D1
Trimble, M1
Okuma, T2
Seifert, J1
Metzner, C1
Paetzold, W1
Borsutzky, M1
Ohlmeier, M1
Passie, T1
Hauser, U1
Becker, H1
Wiese, B1
Emrich, H1
Schneider, U1
Stoner, SC1
Lea, JW1
Wolf, AL1
Berges, AA1
Staller, JA1
Kunwar, A1
Simionescu, M1
Bidzan, L1
Mazza, M1
Della Marca, G1
Di Nicola, M1
Martinotti, G1
Pozzi, G1
Janiri, L1
Bria, P1
Mazza, S1
Savica, R1
Beghi, E1
Mazzaglia, G1
Innocenti, F1
Brignoli, O1
Cricelli, C1
Caputi, AP1
Musolino, R1
Spina, E1
Trifirò, G1
Rajna, P1
Ikeda, M1
Baillieux, H1
Verslegers, W1
Paquier, P1
De Deyn, PP1
Mariën, P1
Sheard, MH1
Ballenger, JC1
Uhde, TW3
Smith, C1
Rubinow, DR4
Bunney, WE2
Keisling, R1
Altmann, H1
Dose, M1
von Zerssen, D1
Jann, MW1
Saklad, SR1
Ereshefsky, L1
Baciewicz, G1
Yerevanian, BI1
Vieweg, V1
Pandurangi, A1
Levenson, J1
Silverman, J1
De Vriese, AS1
Philippe, J1
Van Renterghem, DM1
De Cuyper, CA1
Hindryckx, PH1
Matthys, EG1
Louagie, A1
Lynn, DJ1
Fritze, J1
Beneke, M1
Lanczik, M1
Schneider, B1
Walden, J2
Gross, R1
Grunhaus, L1
Lemke, MR1
Stuhlmann, W1
Bocchetta, A2
Loviselli, A2
Martino, E1
Ketter, TA2
Rouillon, F1
George, MS1
Rosenstein, D1
Kling, MA1
Grunze, H1
Mayer, A1
Düsing, R1
Schirrmacher, K1
Liu, Z1
Bingmann, D1
Gillham, R1
Baker, G1
Thompson, P1
Birbeck, K1
McGuire, A1
Tomlinson, L1
Eckersley, L1
Silveira, C1
Brown, S1
Rittmannsberger, H1
Cherchi, A1
Mossa, P1
Velluzzi, F1
Derai, R1
Manji, HK1
Bebchuk, JM1
Moore, GJ1
Glitz, D1
Hasanat, KA1
Chen, G1
Goodwin, FK1
Baldessarini, RJ1
Jamison, KR1
Bowden, CL1
Corá-Locatelli, G1
Kimbrell, TA1
Berner, J1
Davis, JM1
Janicak, PG1
Hogan, DM1
Iqbal, MM1
Gundlapalli, SP1
Ryan, WG1
Ryals, T1
Passman, TE1
Goldberg, JF1
Burdick, KE1
Roick, C1
Ahrens, B1
Becker, T1
Deckers, CL1
Hekster, YA1
Keyser, A1
van Lier, HJ1
Meinardi, H1
Renier, WO1
Jimerson, DC1
Krska, J1
Corner, DA1
Dolan, JD1
Kamil, R1
Rybakowski, J1
Terao, T1
Friedman, DL1
Kastner, T1
Plummer, AT1
Ruiz, MQ1
Henning, D1
Susan, R1
Weiss, B1
Springer, JA1
Garvey, MJ1
Varney, NR1
Roberts, RJ1
Murphy, DJ1
Kumar, R1
McGennis, A1
Mitsushio, H1
Takashima, M1
Mataga, N1
Toru, M1
Motohashi, N1
Ikawa, K1
Kariya, T1
Svestka, J1
Cesková, E1
Rysánek, R1
Náhunek, K1
Liu, ZZ1
Mei, QY1
Wan, Y1
Lenzi, A1
Lazzerini, F1
Placidi, GF1
Cassano, GB1
Akiskal, HS1
Yamashita, I1
Takahashi, R1
Itoh, H1
Kurihara, M1
Otsuki, S1
Watanabe, S1
Sarai, K1
Hazama, H1
Inanaga, K1
Vieweg, WV2
Godleski, LS2
Evans, RW1
Gualtieri, CT1
Israel, M1
Beaudry, P1
Gold, PW1
Nolen, WA1
Jansen, GS1
Broekman, M1
Kaschka, WP1
Thürauf, N1
Mokrusch, T1
Korth, M1
Chen, CC1
Ko, WK1
Tirrell, C1
DeForest, D1
Schwarcz, G1
Gosenfeld, L1
Gilderman, A1
Jiwesh, J1
Ripple, RE1
Signer, SF1
Benson, DF1
Rudnick, FD1
Obel, AO1
Odwako, DB1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study of Prophylactic Management of Lamotrigine for Bipolar Disorder in Pregnant Women[NCT03774641]20 participants (Anticipated)Observational2018-12-03Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

33 reviews available for carbamazepine and Affective Disorders

ArticleYear
Genetics and antiepileptic mood stabilizer treatment response in bipolar disorder: what do we know?
    Pharmacogenomics, 2021, Volume: 22, Issue:14

    Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Humans; La

2021
Pregnancy Outcomes Following In Utero Exposure to Lamotrigine: A Systematic Review and Meta-Analysis.
    CNS drugs, 2017, Volume: 31, Issue:6

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newbo

2017
Pharmacotherapy for mood disorders in pregnancy: a review of pharmacokinetic changes and clinical recommendations for therapeutic drug monitoring.
    Journal of clinical psychopharmacology, 2014, Volume: 34, Issue:2

    Topics: Antidepressive Agents; Carbamazepine; Drug Monitoring; Female; Humans; Lamotrigine; Mood Disorders;

2014
Understanding the molecular mechanisms underlying mood stabilizer treatments in bipolar disorder: Potential involvement of epigenetics.
    Neuroscience letters, 2018, 03-16, Volume: 669

    Topics: Antimanic Agents; Bipolar Disorder; Carbamazepine; Epigenesis, Genetic; Epigenomics; Humans; Lithium

2018
[Mood stabilizers--past, present and future].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2008, Volume: 10, Issue:1

    Topics: Affect; Antimanic Agents; Bipolar Disorder; Calcium; Carbamazepine; Depressive Disorder; gamma-Amino

2008
Mood stabilizers in pregnancy: a systematic review.
    The Australian and New Zealand journal of psychiatry, 2010, Volume: 44, Issue:11

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Carbamazepin

2010
Tolerance to the prophylactic effects of carbamazepine and related mood stabilizers in the treatment of bipolar disorders.
    CNS neuroscience & therapeutics, 2011, Volume: 17, Issue:6

    Topics: Amygdala; Animals; Anticonvulsants; Bipolar Disorder; Carbamazepine; Drug Resistance; Drug Tolerance

2011
[The optimal combination of ECT with pharmacotherapy].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2011, Volume: 13, Issue:3

    Topics: Affect; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tric

2011
[Oxcarbazepine in the treatment of affective and schizoaffective disorders].
    Fortschritte der Neurologie-Psychiatrie, 2003, Volume: 71, Issue:5

    Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; Human

2003
Search for a common mechanism of mood stabilizers.
    Biochemical pharmacology, 2003, Jul-15, Volume: 66, Issue:2

    Topics: Affect; Animals; Anticonvulsants; Antimanic Agents; Carbamazepine; Glycogen Synthase Kinase 3; Human

2003
[Investigation on the therapeutic effect of carbamazepine on the mood disorders in Japan].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2005, Volume: 107, Issue:5

    Topics: Antidepressive Agents; Carbamazepine; Double-Blind Method; Humans; Japan; Lithium; Mood Disorders

2005
[Anticonvulsants treatment of psychiatric disorder in elderly patients].
    Przeglad lekarski, 2006, Volume: 63, Issue:7

    Topics: Aged; Anticonvulsants; Anxiety Disorders; Bipolar Disorder; Carbamazepine; Epilepsy; Humans; Mental

2006
[Effects of antiepileptic drugs on mood of people with epilepsy].
    Ideggyogyaszati szemle, 2007, Sep-30, Volume: 60, Issue:9-10

    Topics: Affect; Anticonvulsants; Antidepressive Agents; Carbamazepine; Depressive Disorder; Epilepsy; Fructo

2007
Effects of mood stabilizer on the circadian system: possible implication for abnormalities in mood disorders.
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2007, Volume: 130, Issue:6

    Topics: 5'-Nucleotidase; Animals; Antimanic Agents; Biological Clocks; Carbamazepine; Circadian Rhythm; Huma

2007
Clinical pharmacology of aggressive behavior.
    Clinical neuropharmacology, 1984, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aged; Aggression; Anger; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; C

1984
The consulting psychiatrist and the polydipsia-hyponatremia syndrome in schizophrenia.
    International journal of psychiatry in medicine, 1994, Volume: 24, Issue:4

    Topics: Angiotensin II; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Carbamazepine; Cognit

1994
Carbamazepine hypersensitivity syndrome: report of 4 cases and review of the literature.
    Medicine, 1995, Volume: 74, Issue:3

    Topics: Adult; Aged; Carbamazepine; Drug Hypersensitivity; Epilepsy; Female; Humans; Lymphocyte Activation;

1995
A speculative model of affective illness cyclicity based on patterns of drug tolerance observed in amygdala-kindled seizures.
    Molecular neurobiology, 1996, Volume: 13, Issue:1

    Topics: Affect; Amygdala; Animals; Anticonvulsants; Bipolar Disorder; Carbamazepine; Disease Progression; Dr

1996
Modulation of CNS signal transduction pathways and gene expression by mood-stabilizing agents: therapeutic implications.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 2

    Topics: Bipolar Disorder; Calcium-Calmodulin-Dependent Protein Kinases; Carbamazepine; Gene Expression; Glyc

1999
Anticonvulsant therapy and suicide risk in affective disorders.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 2

    Topics: Amitriptyline; Anticonvulsants; Bipolar Disorder; Carbamazepine; Double-Blind Method; Female; Follow

1999
Metabolism and excretion of mood stabilizers and new anticonvulsants.
    Cellular and molecular neurobiology, 1999, Volume: 19, Issue:4

    Topics: Anticonvulsants; Antimanic Agents; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Huma

1999
Mood stabilizers in the prevention of recurrent affective disorders: a meta-analysis.
    Acta psychiatrica Scandinavica, 1999, Volume: 100, Issue:6

    Topics: Antimanic Agents; Carbamazepine; Humans; Lithium Carbonate; Mood Disorders; Prognosis; Recurrence; S

1999
Effects of antimanic mood-stabilizing drugs on fetuses, neonates, and nursing infants.
    Southern medical journal, 2001, Volume: 94, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Antimanic Agents; Benzodiazepines; Breast Feed

2001
Cognitive side effects of anticonvulsants.
    The Journal of clinical psychiatry, 2001, Volume: 62 Suppl 14

    Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cognition Disorders; Cyclohexane

2001
[Prophylactic long-term therapy of affective disorders with lithium, valproic acid and carbamazepine--effectiveness and cost-effectiveness].
    Psychiatrische Praxis, 2001, Volume: 28 Suppl 1

    Topics: Antimanic Agents; Carbamazepine; Cost-Benefit Analysis; Disease Management; Germany; Humans; Lithium

2001
Oxcarbazepine in affective and schizoaffective disorders.
    Pharmacopsychiatry, 2001, Volume: 34, Issue:6

    Topics: Anticonvulsants; Carbamazepine; Humans; Mood Disorders; Oxcarbazepine; Psychotic Disorders

2001
Perspectives in the treatment of the psychoneurological disorders: affective disorders.
    Progress in neuro-psychopharmacology, 1979, Volume: 3, Issue:1-3

    Topics: Animals; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Humans; Mood Disorders; Peptide Frag

1979
Ziskind-Somerfeld Research Award 1992. Endogenous biochemical abnormalities in affective illness: therapeutic versus pathogenic.
    Biological psychiatry, 1992, Sep-15, Volume: 32, Issue:6

    Topics: Amygdala; Carbamazepine; Female; Humans; Kindling, Neurologic; Male; Mental Disorders; Models, Neuro

1992
Mechanisms of the psychotropic action of lithium and carbamazepine.
    Pharmacology & toxicology, 1992, Volume: 71 Suppl 1

    Topics: Brain; Carbamazepine; Drug Synergism; Humans; Lithium; Mood Disorders

1992
Sensitization, kindling, and carbamazepine: an update on their implications for the course of affective illness.
    Pharmacopsychiatry, 1992, Volume: 25, Issue:1

    Topics: Animals; Behavior; Behavior, Animal; Carbamazepine; Humans; Kindling, Neurologic; Mood Disorders; Ps

1992
Sensitization and kindling perspectives for the course of affective illness: toward a new treatment with the anticonvulsant carbamazepine.
    Pharmacopsychiatry, 1990, Volume: 23, Issue:1

    Topics: Carbamazepine; Humans; Kindling, Neurologic; Mood Disorders

1990
Carbamazepine: a neuropsychological and psychiatric profile.
    Clinical neuropharmacology, 1985, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Attention; Blood Proteins; Carbamazepine; Child; Cognition; Epilepsy; Female; Hum

1985
Carbamazepine in psychiatry: a review.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1988, Volume: 33, Issue:7

    Topics: Aggression; Carbamazepine; Humans; Mental Disorders; Mood Disorders

1988

Trials

11 trials available for carbamazepine and Affective Disorders

ArticleYear
Carbamazepine in the treatment of cocaine dependence: subtyping by affective disorder.
    Experimental and clinical psychopharmacology, 2002, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cocaine-Related Disorders; Double-Blind Method; F

2002
Plasma levels of leptin and endogenous immune modulators during treatment with carbamazepine or lithium.
    Psychopharmacology, 2005, Volume: 179, Issue:2

    Topics: Adult; Antimanic Agents; Bipolar Disorder; Body Mass Index; Body Weight; Carbamazepine; Female; Huma

2005
Mood and affect during detoxification of opiate addicts: a comparison of buprenorphine versus methadone.
    Addiction biology, 2005, Volume: 10, Issue:2

    Topics: Adult; Anticonvulsants; Buprenorphine; Carbamazepine; Diagnostic and Statistical Manual of Mental Di

2005
Oxcarbazepine improves mood in patients with epilepsy.
    Epilepsy & behavior : E&B, 2007, Volume: 10, Issue:3

    Topics: Adult; Analysis of Variance; Anticonvulsants; Antidepressive Agents; Anxiety; Carbamazepine; Case-Co

2007
Therapeutic effects of GABA-ergic drugs in affective disorders. A preliminary report.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Analgesics; Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as

1983
Carbamazepine as adjunct or alternative to lithium in the prophylaxis of recurrent affective disorders.
    Pharmacopsychiatry, 1994, Volume: 27, Issue:5

    Topics: Adult; Carbamazepine; Drug Therapy, Combination; Female; Humans; Lithium; Male; Mood Disorders; Recu

1994
Standardisation of a self-report questionnaire for use in evaluating cognitive, affective and behavioural side-effects of anti-epileptic drug treatments.
    Epilepsy research, 1996, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Affect; Aging; Anticonvulsants; Behavior; Carbamazepine; Cognition Disorders; Dou

1996
Anticonvulsant therapy and suicide risk in affective disorders.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 2

    Topics: Amitriptyline; Anticonvulsants; Bipolar Disorder; Carbamazepine; Double-Blind Method; Female; Follow

1999
Monotherapy versus polytherapy for epilepsy: a multicenter double-blind randomized study.
    Epilepsia, 2001, Volume: 42, Issue:11

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cognition Disorders; Double-Blind Method; Drug Ad

2001
Predictors of compliance with lithium and carbamazepine regimens in the long-term treatment of recurrent mood and related psychotic disorders.
    Pharmacopsychiatry, 1989, Volume: 22, Issue:1

    Topics: Aged; Aged, 80 and over; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Female; Human

1989
Carbamazepine in recurrent affective disorders?
    Drug and therapeutics bulletin, 1986, Jul-28, Volume: 24, Issue:15

    Topics: Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Humans; Mood Disorders; Recurrence

1986

Other Studies

53 other studies available for carbamazepine and Affective Disorders

ArticleYear
Cobalamin deficiency manifested with seizures, mood oscillations, psychotic features and reversible dementia in the absence of typical neurologic and hematologic signs and symptoms: a case report.
    Collegium antropologicum, 2013, Volume: 37, Issue:1

    Topics: Carbamazepine; Dementia; Diazepam; Electroencephalography; Haloperidol; Hematology; Humans; Hydroxoc

2013
International prescribing patterns for mood illness: the International Mood Network (IMN).
    Journal of affective disorders, 2014, Volume: 167

    Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Asia; Bipolar Disorder; Carbamazepine

2014
The number of past manic episodes is the best predictor of antidepressant-emergent manic switch in a cohort of bipolar depressed patients.
    Psychiatry research, 2016, 06-30, Volume: 240

    Topics: Adult; Affect; Aged; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Carbamazepine; Depre

2016
Effect of lamotrigine and carbamazepine on corticotropin-releasing factor-associated serotonergic transmission in rat dorsal raphe nucleus.
    Psychopharmacology, 2012, Volume: 220, Issue:3

    Topics: Animals; Anticonvulsants; Carbamazepine; Corticotropin-Releasing Hormone; Dose-Response Relationship

2012
[Cardiologic interaction carbamazepine with atypical neuroleptics. Acute mixed carbamazepine and quetiapine intoxication--case report].
    Przeglad lekarski, 2011, Volume: 68, Issue:8

    Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Arrhythmias, Cardiac; Bipolar Disorde

2011
Self-reported adherence to treatment with mood stabilizers, plasma levels, and psychiatric hospitalization.
    The American journal of psychiatry, 2002, Volume: 159, Issue:11

    Topics: Adolescent; Aged; Antimanic Agents; Biological Availability; Bipolar Disorder; Carbamazepine; Drug T

2002
Mood-stabilizers: the archeology of the concept.
    Bipolar disorders, 2003, Volume: 5, Issue:6

    Topics: Affect; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Concept Formation; Forec

2003
Adjunctive oxcarbazepine in comorbid anxiety and affective disorder with hyponatremic seizure: case analysis and literature review.
    Epilepsy & behavior : E&B, 2003, Volume: 4, Issue:6

    Topics: Adult; Anticonvulsants; Anxiety; Carbamazepine; Comorbidity; Drug Therapy, Combination; Follow-Up St

2003
Reduction of affective lability and alcohol use following traumatic brain injury: a clinical pilot study of anti-convulsant medications.
    Brain injury, 2005, Volume: 19, Issue:4

    Topics: Adult; Alcoholism; Anticonvulsants; Anxiety Disorders; Brain Injuries; Carbamazepine; Female; Humans

2005
Antiepileptic drugs and the regulation of mood and quality of life (QOL): the evidence from epilepsy.
    Epilepsia, 2005, Volume: 46 Suppl 4

    Topics: Affect; Anticonvulsants; Carbamazepine; Epilepsy; Health Status; Humans; Lamotrigine; Mood Disorders

2005
Levetiracetam for mood stabilization and maintenance of seizure control following multiple treatment failures.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:11

    Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Female; Fructose; Humans; Levetiracetam;

2005
Oxcarbazepine in the treatment of child psychiatric disorders: a retrospective chart review.
    Journal of child and adolescent psychopharmacology, 2005, Volume: 15, Issue:6

    Topics: Adolescent; Anger; Antipsychotic Agents; Carbamazepine; Child; Child Behavior Disorders; Drug Admini

2005
Prescribing patterns of antiepileptic drugs in Italy: a nationwide population-based study in the years 2000-2005.
    European journal of neurology, 2007, Volume: 14, Issue:12

    Topics: Adolescent; Adult; Age Distribution; Aged; Amines; Anticonvulsants; Carbamazepine; Catchment Area, H

2007
Cerebellar cognitive affective syndrome associated with topiramate.
    Clinical neurology and neurosurgery, 2008, Volume: 110, Issue:5

    Topics: Amines; Anticonvulsants; Carbamazepine; Cerebellar Diseases; Cerebellum; Cognition Disorders; Cycloh

2008
Effect of carbamazepine on cyclic nucleotides in CSF of patients with affective illness.
    Biological psychiatry, 1982, Volume: 17, Issue:9

    Topics: Adult; Affective Disorders, Psychotic; Aged; Bipolar Disorder; Carbamazepine; Cyclic AMP; Cyclic GMP

1982
Carbamazepine and lithium carbonate in the treatment of refractory affective disorders.
    Archives of general psychiatry, 1983, Volume: 40, Issue:2

    Topics: Adult; Bipolar Disorder; Carbamazepine; Depressive Disorder; Humans; Lithium; Lithium Carbonate; Mal

1983
Biochemical mechanisms of action of carbamazepine in affective illness and epilepsy.
    Psychopharmacology bulletin, 1984,Summer, Volume: 20, Issue:3

    Topics: Carbamazepine; Epilepsy; Humans; Mood Disorders

1984
Carbamazepine for patients with affective target symptoms.
    Drug intelligence & clinical pharmacy, 1984, Volume: 18, Issue:1

    Topics: Bipolar Disorder; Carbamazepine; Female; Humans; Male; Mood Disorders

1984
Thrombocytopenia associated with carbamazepine: case report and review.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:7

    Topics: Aged; Blood Cell Count; Carbamazepine; Depressive Disorder; Female; Humans; Mood Disorders; Thromboc

1984
Sensitization and oscillation following repeated stimulation: relationship to affective illness and its treatment with lithium and carbamazepine [proceedings].
    Psychopharmacology bulletin, 1980, Volume: 16, Issue:4

    Topics: Animals; Carbamazepine; Humans; Lithium; Mood Disorders

1980
Lithium in steroid-induced depression.
    The British journal of psychiatry : the journal of mental science, 1995, Volume: 166, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Carbamazepine; Female; Humans; Lithium; Mood Disorders

1995
Choosing lithium, anticonvulsant, or electroconvulsant therapy for mood disorders.
    Southern medical journal, 1995, Volume: 88, Issue:2

    Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Controlled Clinical Trials as Topic; Electroconvul

1995
[Therapeutic use of carbamazepine for treatment of agitation and affective disorders in geriatric psychiatry patients].
    Psychiatrische Praxis, 1994, Volume: 21, Issue:4

    Topics: Aged; Carbamazepine; Dementia; Dose-Response Relationship, Drug; Drug Administration Schedule; Femal

1994
Thyroid function during carbamazepine.
    Biological psychiatry, 1994, Jul-15, Volume: 36, Issue:2

    Topics: Carbamazepine; Humans; Hypothyroidism; Mood Disorders; Thyroid Function Tests; Thyroid Hormones; Thy

1994
[Mood regulator agents (excluding lithium)].
    La Revue du praticien, 1994, Nov-01, Volume: 44, Issue:17

    Topics: Anticonvulsants; Carbamazepine; Contraindications; Humans; Mood Disorders

1994
CSF magnesium in affective disorder: lack of correlation with clinical course of treatment.
    Psychiatry research, 1994, Volume: 51, Issue:2

    Topics: Adult; Carbamazepine; Female; Humans; Lithium; Magnesium; Male; Mood Disorders; Sex Factors; Spinal

1994
Calcium-antagonistic effects of carbamazepine in epilepsies and affective psychoses.
    Neuropsychobiology, 1993, Volume: 27, Issue:3

    Topics: Animals; Caffeine; Calcium Channel Blockers; Carbamazepine; Epilepsy; Guinea Pigs; Hippocampus; In V

1993
Asterixis induced by psychotropic drug treatment.
    Clinical neuropharmacology, 1996, Volume: 19, Issue:4

    Topics: Adult; Aged; Carbamazepine; Clozapine; Female; Humans; Male; Middle Aged; Mood Disorders; Psychotrop

1996
Six-year follow-up of thyroid function during lithium treatment.
    Acta psychiatrica Scandinavica, 1996, Volume: 94, Issue:1

    Topics: Antibodies; Anticonvulsants; Antipsychotic Agents; Carbamazepine; Drug Therapy, Combination; Female;

1996
Effects of medical interventions on suicidal behavior. Summary and conclusions.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 2

    Topics: Anticonvulsants; Carbamazepine; Comorbidity; Depressive Disorder; Health Education; Humans; Lithium;

1999
Introduction: the use of mood stabilizers in the treatment of psychiatric disorders.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 5

    Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Humans; Li

1999
Lithium-treated mood disorders, paroxysmal rhinorrhea, and mesial temporal lobe epilepsy.
    The Journal of neuropsychiatry and clinical neurosciences, 1999,Summer, Volume: 11, Issue:3

    Topics: Adult; Antimanic Agents; Carbamazepine; Cerebrospinal Fluid Rhinorrhea; Epilepsy, Temporal Lobe; Fem

1999
Serum drug level monitoring in affective disorders.
    Journal of clinical pharmacy and therapeutics, 1992, Volume: 17, Issue:6

    Topics: Carbamazepine; Dose-Response Relationship, Drug; Humans; Lithium; Monitoring, Physiologic; Mood Diso

1992
Atypical affective disorder with episodic dyscontrol: a case of von Economo's disease (encephalitis lethargica).
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1992, Volume: 37, Issue:2

    Topics: Adult; Antipsychotic Agents; Carbamazepine; Chlorpromazine; Chronic Disease; Electroencephalography;

1992
Episodic dyscontrol.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 161

    Topics: Carbamazepine; Humans; Mood Disorders; Neurocognitive Disorders

1992
Adverse behavioral effects in individuals with mental retardation and mood disorders treated with carbamazepine.
    American journal of mental retardation : AJMR, 1992, Volume: 96, Issue:5

    Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Female; Humans;

1992
Dichotic listening failure in dysphoric neuropsychiatric patients who endorse multiple seizure-like symptoms.
    The Journal of nervous and mental disease, 1991, Volume: 179, Issue:8

    Topics: Adult; Anxiety Disorders; Auditory Perception; Auditory Threshold; Carbamazepine; Depressive Disorde

1991
Carbamazepine in affective disorders.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 156

    Topics: Carbamazepine; Humans; Mood Disorders

1990
Effects of chronic treatment with trihexyphenidyl and carbamazepine alone or in combination with haloperidol on substance P content in rat brain: a possible implication of substance P in affective disorders.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:3

    Topics: Animals; Body Weight; Brain Chemistry; Carbamazepine; Dopamine; Dose-Response Relationship, Drug; ga

1988
GABAB receptors are up-regulated by chronic treatment with lithium or carbamazepine. GABA hypothesis of affective disorders?
    European journal of pharmacology, 1989, Jul-04, Volume: 166, Issue:1

    Topics: Animals; Baclofen; Carbamazepine; Cerebral Cortex; gamma-Aminobutyric Acid; Hippocampus; Lithium; Ma

1989
Controlled cross-over comparison of carbamazepine with perphenazine in schizophrenic psychoses.
    Activitas nervosa superior, 1989, Volume: 31, Issue:4

    Topics: Adult; Antipsychotic Agents; Carbamazepine; Female; Humans; Male; Middle Aged; Mood Disorders; Perph

1989
[A follow-up study on rapid cycling affective disorders].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1989, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Aged; Carbamazepine; Cyclothymic Disorder; Female; Follow-Up Studies; Humans; Lit

1989
Clinical efficacy of carbamazepine in affective, schizoaffective, and schizophrenic disorders.
    Pharmacopsychiatry, 1989, Volume: 22, Issue:2

    Topics: Adult; Carbamazepine; Female; Humans; Male; Middle Aged; Mood Disorders; Psychiatric Status Rating S

1989
Polydipsia, hyponatremia, and psychosis.
    The American journal of psychiatry, 1989, Volume: 146, Issue:1

    Topics: Carbamazepine; Drinking; Drug Therapy, Combination; Humans; Hyponatremia; Inappropriate ADH Syndrome

1989
Effect of carbamazepine on mean urinary free cortisol excretion in patients with major affective illness.
    Psychopharmacology, 1986, Volume: 88, Issue:1

    Topics: Carbamazepine; Humans; Hydrocortisone; Mood Disorders; Radioimmunoassay; Time Factors

1986
Measuring plasma levels of carbamazepine. A pharmacokinetic study in patients with affective disorders.
    Pharmacopsychiatry, 1988, Volume: 21, Issue:5

    Topics: Adult; Aged; Bipolar Disorder; Carbamazepine; Female; Humans; Male; Middle Aged; Mood Disorders

1988
Electrooculography and dark adaptation in patients with affective and schizoaffective psychoses: early physiological effects of carbamazepine and lithium.
    Pharmacopsychiatry, 1988, Volume: 21, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Carbamazepine; Dark Adaptation; Electrooculography; Female; Humans;

1988
Carbamazepine and hyponatremia.
    The American journal of psychiatry, 1988, Volume: 145, Issue:10

    Topics: Carbamazepine; Drug Therapy, Combination; Humans; Hyponatremia; Lithium; Mood Disorders

1988
[A clinical study on combined lithium and carbamazepine treatment of major affective disorders].
    Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences, 1987, Volume: 3, Issue:3

    Topics: Adult; Carbamazepine; Drug Therapy, Combination; Female; Humans; Lithium; Male; Mood Disorders; Recu

1987
Neuroendocrine factors in affective disorders.
    Archives of psychiatric nursing, 1987, Volume: 1, Issue:4

    Topics: Carbamazepine; Humans; Lithium; Mood Disorders; Neurosecretory Systems

1987
Akathisia associated with carbamazepine therapy.
    The American journal of psychiatry, 1986, Volume: 143, Issue:9

    Topics: Adult; Akathisia, Drug-Induced; Carbamazepine; Humans; Male; Mood Disorders

1986
Undetected affective disorder in the developmentally retarded.
    The American journal of psychiatry, 1986, Volume: 143, Issue:2

    Topics: Adult; Carbamazepine; Depressive Disorder; Humans; Intellectual Disability; Male; Mood Disorders

1986
Practical therapeutics: the use of carbamazepine in affective disorders.
    East African medical journal, 1985, Volume: 62, Issue:3

    Topics: Carbamazepine; Humans; Mood Disorders

1985