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carbamazepine and Acute Liver Injury, Drug-Induced

carbamazepine has been researched along with Acute Liver Injury, Drug-Induced in 112 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Research Excerpts

ExcerptRelevanceReference
"The patient was a 51-year-old man who had been prescribed carbamazepine for right third-branch trigeminal neuralgia."7.77A case of drug-induced hypersensitivity syndrome due to carbamazepine. ( Arisaka, T; Fukushima, D; Morimoto, M; Takada, A; Takahashi, S; Tanaka, Y; Tonogi, M; Watanabe, Y; Yamane, GY, 2011)
"To determine the influence of valproate (VPA) treatment on acylcarnitines in children with epilepsy."7.74Effects of valproate on acylcarnitines in children with epilepsy using ESI-MS/MS. ( Gerstner, T; Koenig, SA; Kohlmueller, D; Longin, E; Mehlem, P; Schulze, A; Teich, M; Treiss, I; Werner, T, 2007)
"To report a case of transient cholestatic hepatitis occurring in an infant between the third and seventh weeks of life, most likely due to carbamazepine exposure during pregnancy and breast feeding."7.71Neonatal cholestatic hepatitis from carbamazepine exposure during pregnancy and breast feeding. ( Braegger, CP; Frey, B; Ghelfi, D, 2002)
" Two patients presented severe febrile skin eruption following drug intake (carbamazepine or sulfazalazine), with hypereosinophilia and hepatitis."7.71[DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome after sulfasalazine and carmazepine: report of two cases]. ( Catteau, B; Delcey, V; Devulder, B; Fauchais, AL; Hachulla, E; Hatron, PY; Launay, D; Legout, L; Michon-Pasturel, U; Queyrel, V, 2001)
"We report a 3-week-old boy with cholestatic hepatitis, most likely due to carbamazepine exposure during pregnancy and breastfeeding."7.68Transient cholestatic hepatitis in a neonate associated with carbamazepine exposure during pregnancy and breast-feeding. ( Frey, B; Musy, JP; Schubiger, G, 1990)
"Three cases of carbamazepine-induced granulomatous hepatitis are reported."7.66Granulomatous hepatitis secondary to carbamazepine. ( Goodman, MW; Levy, M; Sumner, HW; Van Dyne, BJ, 1981)
"When thrombocytopenia is noted, prompt withdrawal of the drug is required."5.27Carbamazepine-induced thrombocytopenia, rash, and hepatic dysfunction. ( Ponte, CD, 1983)
"Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment."5.27Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983)
"Carbamazepine was then reinstituted for 4 days, resulting in fever, upper abdominal pain and deteriorating liver function."5.26Granulomatous hepatitis in a patient receiving carbamazepine. ( Levander, HG, 1980)
" As for SCARs, associations of HLA-B*15:02 or HLA-A*31:01 and HLA-B*58:01 have been revealed for carbamazepine- and allopurinol-related Stevens-Johnson syndrome and toxic epidermal neclolysis, respectively."4.89Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury. ( Kaniwa, N; Saito, Y, 2013)
"This review analyses the concept of extended-release (ER) formulations in epilepsy and evaluates ER formulations of carbamazepine, valproic acid and a modified-release (MR) formulation of oxcarbazepine."4.84Extended-release formulations for the treatment of epilepsy. ( Bialer, M, 2007)
"The patient was a 51-year-old man who had been prescribed carbamazepine for right third-branch trigeminal neuralgia."3.77A case of drug-induced hypersensitivity syndrome due to carbamazepine. ( Arisaka, T; Fukushima, D; Morimoto, M; Takada, A; Takahashi, S; Tanaka, Y; Tonogi, M; Watanabe, Y; Yamane, GY, 2011)
"A 43-year-old woman was being treated with oxcarbazepine for depression and was started on lamotrigine 2 weeks prior to her presentation."3.74Lamotrigine-associated reversible severe hepatitis: a case report. ( Olson, KR; Su-Yin, AN; Tai, WW, 2008)
"To determine the influence of valproate (VPA) treatment on acylcarnitines in children with epilepsy."3.74Effects of valproate on acylcarnitines in children with epilepsy using ESI-MS/MS. ( Gerstner, T; Koenig, SA; Kohlmueller, D; Longin, E; Mehlem, P; Schulze, A; Teich, M; Treiss, I; Werner, T, 2007)
"To report a case of transient cholestatic hepatitis occurring in an infant between the third and seventh weeks of life, most likely due to carbamazepine exposure during pregnancy and breast feeding."3.71Neonatal cholestatic hepatitis from carbamazepine exposure during pregnancy and breast feeding. ( Braegger, CP; Frey, B; Ghelfi, D, 2002)
"A 42-year-old woman presented with acute bullous skin lesions and angio-oedema that had developed 3 months after initiation of treatment with carbamazepine for epilepsy."3.71Non-alcoholic steatohepatitis induced by carbamazepine and variegate porphyria. ( Alfei, B; Bianco, A; Biolcati, G; Di Rocco, P; Gasbarrini, G; Grieco, A; Griso, D; Miele, L; Vecchio, FM, 2001)
" Two patients presented severe febrile skin eruption following drug intake (carbamazepine or sulfazalazine), with hypereosinophilia and hepatitis."3.71[DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome after sulfasalazine and carmazepine: report of two cases]. ( Catteau, B; Delcey, V; Devulder, B; Fauchais, AL; Hachulla, E; Hatron, PY; Launay, D; Legout, L; Michon-Pasturel, U; Queyrel, V, 2001)
"A 44-year-old woman known to be allergic to phenytoin was treated with carbamazepine for 1 month and developed fever, lymphadenopathy, pneumonitis, hepatitis, and a morbilliform eruption."3.70Carbamazepine-induced pseudolymphoma with CD-30 positive cells. ( Belsito, DV; Nathan, DL, 1998)
"Carbamazepine is a potent anticonvulsant agent with proven efficacy in the treatment of partial and tonic-clonic seizures."3.70Suspected carbamazepine-induced hepatotoxicity. ( Morales-Diaz, M; Pinilla-Roa, E; Ruiz, I, 1999)
"The effects of acute carbamazepine (CBZ) administration on haem metabolism in rat liver were examined in relation to the mechanism by which it exacerbates hepatic porphyrias."3.68Effects of acute carbamazepine administration on haem metabolism in rat liver. ( Badawy, AA; Morgan, CJ, 1992)
"We report a 3-week-old boy with cholestatic hepatitis, most likely due to carbamazepine exposure during pregnancy and breastfeeding."3.68Transient cholestatic hepatitis in a neonate associated with carbamazepine exposure during pregnancy and breast-feeding. ( Frey, B; Musy, JP; Schubiger, G, 1990)
"Three cases of carbamazepine-induced granulomatous hepatitis are reported."3.66Granulomatous hepatitis secondary to carbamazepine. ( Goodman, MW; Levy, M; Sumner, HW; Van Dyne, BJ, 1981)
"Rare, serious adverse effects of antiepileptic drugs (AEDs) include hepatotoxicity and bone marrow suppression."2.38Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy. ( Wyllie, E; Wyllie, R, 1991)
"These include 27 cases of aplastic anemia and 10 of agranulocytosis."2.37Carbamazepine side effects in children and adults. ( Pellock, JM, 1987)
"We present a female with seizures one month after delivery who had borderline elevated liver enzymes prior to the initiation of OXC treatment."1.39Acute oxcarbazepine-induced hepatotoxicity in a patient susceptible to developing drug-induced liver injury. ( Bielen, A; Bielen, I; Marusić, M; Planjar-Prvan, M; Sruk, A, 2013)
"Carbamazepine (CBZ) is a widely used antiepileptic agent."1.38Metabolic activation and inflammation reactions involved in carbamazepine-induced liver injury. ( Fukami, T; Higuchi, S; Nakajima, M; Takai, S; Tsuneyama, K; Yano, A; Yokoi, T, 2012)
" We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts."1.37FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011)
" An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems."1.36Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010)
" This raises caution that patients on carbamazepine should avoid chronic use of acetaminophen, and if required use at lower doses with vigilant monitoring for signs of liver damage."1.35Acetaminophen toxicity with concomitant use of carbamazepine. ( Ahmed, SN; Heino, A; Jickling, G, 2009)
"The carbamazepine treatment was stopped and laboratory parameters improved."1.34[Carbamazepine hepatoxicity--a case report]. ( Gawlikowski, T; Hydzik, P, 2007)
" After discontinuing RTV and reducing the dosage of CBZ, the serum concentration of CBZ returned to the optimal range, symptoms subsided, and liver function returned to baseline."1.31Potential interaction between ritonavir and carbamazepine. ( Feldman, MD; Fujii, T; Kato, Y; Kayser, SR; Mizoguchi, N; Takata, N; Ueda, K, 2000)
"Carbamazepine is a drug commonly used in the treatment of neuropathic pain."1.29Carbamazepine-induced hepatitis in a patient with cervical myelopathy. ( Kong, KH, 1996)
"Her ageusia was related to a variety of causes including an unbalanced diet, administration of the anti-epileptic drug, carbamazepine and psychological factors."1.29Case of ageusia from a variety of causes. ( Deguchi, K; Furuta, S; Imakiire, T; Ohyama, M, 1996)
"In this patient, an initial episode of photosensitization, probably elicited by clomipramine, was accompanied by contact allergy to this drug and to carbamazepine."1.28A case of photosensitivity and contact allergy to systemic tricyclic drugs, with unusual features. ( Bojs, G; Ljunggren, B, 1991)
" Other features of this adverse drug reaction were unremitting fever, leukocytosis with eosinophilia and atypical lymphocytosis, and proteinuria."1.28Phenobarbital hepatotoxicity in an 8-month-old infant. ( Goldbach, M; Phillips, MJ; Roberts, EA; Spielberg, SP, 1990)
"A 72-year-old woman with toxic hepatitis due to carbamazepine is presented."1.28[Carbamazepine-associated hepatitis]. ( Dann, EJ; Gillis, S, 1990)
"When thrombocytopenia is noted, prompt withdrawal of the drug is required."1.27Carbamazepine-induced thrombocytopenia, rash, and hepatic dysfunction. ( Ponte, CD, 1983)
" However, whereas toxic reactions following phenytoin and carbamazepine are characterised by a rather short duration of exposure before symptoms occur with accompanying clinical features of hypersensitivity, valproate-induced hepatic toxicity exhibits no signs of hypersensitivity and often occurs following prolonged exposure, speaking in favor of a metabolic aberration as the underlying cause."1.27Hepatic toxicity of antiepileptic drugs: a review. ( Bentsen, KD; Gram, L, 1983)
"Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment."1.27Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983)
" Frequency and extent of increased activity of gamma-GT were highly related to daily dosage in both preparations."1.27The influence of long-term anticonvulsant therapy with diphenylhydantoin and carbamazepine on serum gamma-glutamyltransferase, aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase. ( Aldenhövel, HG, 1988)
"Carbamazepine was then reinstituted for 4 days, resulting in fever, upper abdominal pain and deteriorating liver function."1.26Granulomatous hepatitis in a patient receiving carbamazepine. ( Levander, HG, 1980)

Research

Studies (112)

TimeframeStudies, this research(%)All Research%
pre-199036 (32.14)18.7374
1990's22 (19.64)18.2507
2000's21 (18.75)29.6817
2010's31 (27.68)24.3611
2020's2 (1.79)2.80

Authors

AuthorsStudies
Yogeeswari, P1
Sriram, D1
Thirumurugan, R1
Raghavendran, JV1
Sudhan, K1
Pavana, RK1
Stables, J1
Rana, A1
Siddiqui, N1
Khan, SA1
Ehtaishamul Haque, S1
Bhat, MA1
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Greene, N1
Fisk, L1
Naven, RT1
Note, RR1
Patel, ML1
Pelletier, DJ1
Ekins, S1
Williams, AJ1
Xu, JJ1
Chen, M2
Vijay, V1
Shi, Q2
Liu, Z2
Fang, H2
Tong, W3
Dawson, S1
Stahl, S2
Paul, N1
Barber, J1
Kenna, JG2
Ding, D1
Kelly, R1
Sakatis, MZ1
Reese, MJ1
Harrell, AW1
Taylor, MA1
Baines, IA1
Chen, L1
Bloomer, JC1
Yang, EY1
Ellens, HM1
Ambroso, JL1
Lovatt, CA1
Ayrton, AD1
Clarke, SE1
Warner, DJ1
Chen, H1
Cantin, LD1
Walker, CL1
Noeske, T1
Morgan, RE1
van Staden, CJ1
Chen, Y2
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Afshari, CA1
Hamadeh, HK1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
Chalasani, N1
Bonkovsky, HL1
Stine, JG1
Gu, J1
Barnhart, H1
Jacobsen, E1
Björnsson, E1
Fontana, RJ1
Kleiner, DE1
Hoofnagle, JH1
Wang, Z1
Xu, G1
Zhan, X1
Liu, Y1
Gao, Y1
Chen, N1
Guo, Y1
Li, R1
He, T1
Song, X1
Niu, M1
Wang, J1
Bai, Z2
Xiao, X1
Jia, K1
Chen, G1
Liao, X1
Cao, Z1
Zhao, Y1
Zhang, C1
Lu, H1
Visentin, M1
Lenggenhager, D1
Gai, Z1
Kullak-Ublick, GA1
Sasaki, E3
Yokoi, T4
Jacobs, TG1
Burger, DM1
Pranger, AD1
Khoo, SH1
Drenth, JPH1
van Crevel, R1
Nicoletti, P1
Barrett, S1
McEvoy, L1
Daly, AK2
Aithal, G1
Lucena, MI1
Andrade, RJ1
Wadelius, M1
Hallberg, P1
Stephens, C1
Bjornsson, ES1
Friedmann, P1
Kainu, K1
Laitinen, T1
Marson, A1
Molokhia, M1
Phillips, E1
Pichler, W1
Romano, A1
Shear, N1
Sills, G1
Tanno, LK1
Swale, A1
Floratos, A1
Shen, Y1
Nelson, MR1
Watkins, PB1
Daly, MJ1
Morris, AP1
Alfirevic, A1
Pirmohamed, M3
Kaniwa, N1
Saito, Y1
Planjar-Prvan, M1
Bielen, A1
Sruk, A1
Marusić, M1
Bielen, I1
Smith, K1
Fredriksson, L1
Wink, S1
Herpers, B1
Benedetti, G1
Hadi, M2
de Bont, H1
Groothuis, G1
Luijten, M1
Danen, E1
de Graauw, M1
Meerman, J1
van de Water, B1
Eun, JW1
Bae, HJ1
Shen, Q1
Park, SJ1
Kim, HS1
Shin, WC1
Yang, HD1
Jin, CY1
You, JS1
Kang, HJ1
Kim, H1
Ahn, YM1
Park, WS1
Lee, JY1
Nam, SW1
Iida, A2
Yano, A2
Tsuneyama, K3
Fukami, T3
Nakajima, M3
Brotherton, BJ1
Steinberg, I1
Johnson, JL1
Peyre, L1
de Sousa, G1
Barcellini-Couget, S1
Luzy, AP1
Zucchini-Pascal, N1
Rahmani, R1
Oda, S1
Kano, Y1
Hirahara, K1
Asano, Y1
Shiohara, T1
Su-Yin, AN1
Tai, WW1
Olson, KR1
Franciotta, D1
Kwan, P1
Perucca, E1
Crespo Pérez, L1
Moreira Vicente, V1
Cano Ruiz, A1
Gobernado Serrano, JM1
Cobo Ibañez, N1
Milicua Salamero, JM1
Jickling, G1
Heino, A1
Ahmed, SN1
Hsu, HF1
Huang, SY1
Morimoto, M1
Watanabe, Y1
Arisaka, T1
Takada, A1
Tonogi, M1
Yamane, GY1
Fukushima, D1
Takahashi, S1
Tanaka, Y1
Bollaert, M1
Jeulin, H1
Waton, J1
Gastin, I1
Tréchot, P1
Rabaud, C1
Schmutz, JL1
Barbaud, A1
Higuchi, S1
Takai, S1
Starokozhko, V1
Merema, MT1
Groothuis, GM1
Parikh, S1
Dillon, LC1
Scharf, SL1
Penela Vélez de Guevara, MT1
Puente Sánchez, MC1
Jiménez Moya, AI1
Herrera Martín, M1
Romero Escós, MD1
Himmerich, H1
Nickel, T1
Dalal, MA1
Müller, MB1
Werner, T1
Treiss, I1
Kohlmueller, D1
Mehlem, P1
Teich, M1
Longin, E1
Gerstner, T1
Koenig, SA1
Schulze, A1
Réaud, S1
Oberti, F1
Leclech, C1
Calès, P1
Ueda, K2
Ishitsu, T1
Seo, T1
Ueda, N1
Murata, T1
Hori, M1
Nakagawa, K1
Bialer, M1
Gawlikowski, T1
Hydzik, P1
Berkovic, SF1
Bladin, PF1
Jones, DB1
Smallwood, RA1
Vajda, FJ1
Ponte, CD1
Rozov, VD1
Zaporozhskiĭ, VM1
Keränen, T1
Sivenius, J1
Gram, L1
Bentsen, KD1
Paladini, G1
Marinig, L1
Okada, Y1
Watanabe, T1
Kajiwara, E1
Tsuji, H1
Murai, K1
Akagi, K1
Onoyama, K1
Omae, T1
Rigau Cañardo, J1
Bruguera, M1
Sese, J1
Morlans, G1
Diaz-Torres, MA1
Caraballo, R1
Ollero, M1
Lissen, E1
Davion, T2
Capron, JP2
Andrejak, M2
Geoffroy, P1
Capron-Chivrac, D2
Quénum, C1
Rolland, JC1
Autret, E1
Drucker, J1
Grande-Ponte, MC1
Billard, C1
Laugier, J1
Grenier, B1
Soffer, EE1
Taylor, RJ1
Bertram, PD1
Haggitt, RC1
Levinson, MJ1
Orozco López, P1
Román Martínez, J1
Sorribes Puelles, R1
Trilla Soler, M1
Pujol Fernández, C1
Levy, M1
Goodman, MW1
Van Dyne, BJ1
Sumner, HW1
Mitchell, MC1
Boitnott, JK1
Arregui, A1
Maddrey, WC1
Hopen, G1
Nesthus, I1
Laerum, OD1
Levander, HG1
Callaghan, N1
Majeed, T1
O'Connell, A1
Oliveira, DB2
Froomes, PR1
Stewart, MR1
Baischer, W1
Wagner, A1
Seidler, D1
Musalek, M1
Laggner, A1
Kong, KH1
Deguchi, K1
Furuta, S1
Imakiire, T1
Ohyama, M1
Ramsay, SG1
Clee, MD1
Nathan, DL1
Belsito, DV1
Morales-Diaz, M1
Pinilla-Roa, E1
Ruiz, I1
Kaufman, KR1
Nari, G1
Kato, Y1
Fujii, T1
Mizoguchi, N1
Takata, N1
Feldman, MD1
Kayser, SR1
Haukeland, JW1
Jahnsen, J1
Raknerud, N1
Yamaki, M1
Yoshida, I1
Queyrel, V1
Catteau, B1
Michon-Pasturel, U1
Fauchais, AL1
Delcey, V1
Launay, D1
Legout, L1
Hachulla, E1
Hatron, PY1
Devulder, B1
Grieco, A1
Alfei, B1
Di Rocco, P1
Miele, L1
Biolcati, G1
Griso, D1
Vecchio, FM1
Bianco, A1
Gasbarrini, G1
Frey, B2
Braegger, CP1
Ghelfi, D1
Knudsen, L1
Jensen, KB1
Huf, RL1
Schain, RJ1
Zucker, P1
Daum, F1
Cohen, MI1
Viani, F1
Claris-Appiani, A1
Rossi, LN1
Giani, M1
Romeo, A1
Kitteringham, NR1
Breckenridge, AM1
Park, BK1
Morgan, CJ1
Badawy, AA1
Wyllie, E1
Wyllie, R1
Ljunggren, B1
Bojs, G1
Foster, GR1
Goldin, RD1
Freeth, CJ1
Nieman, E1
Gillis, S1
Dann, EJ1
Hintsche-Kilger, BB1
Fengler, JD1
Baumgarten, R1
Schubiger, G1
Musy, JP1
Askmark, H1
Wiholm, BE1
Roberts, EA1
Spielberg, SP1
Goldbach, M1
Phillips, MJ1
Hadzić, N1
Portmann, B1
Davies, ET1
Mowat, AP1
Mieli-Vergani, G1
Aldenhövel, HG1
Ramsay, RE1
Pellock, JM1
Moore, NC1
Lerer, B1
Meyendorff, E1
Gershon, S1
Matsukura, H1
Suzuki, Y1
Olsson, R1
Zettergren, L1
Swinburn, BA1
Croxson, MS1
Miller, MV1
Crawford, KB1
Noguerado, A1
Isasia, T1
Martínez, MC1
García-Sánchez, A1
Costa, JF1
Sramek, JJ1
Herrera, JM1
Canterbury, RJ1
Bastús, JB1
Galeone, D1
Lamontanara, G1
Torelli, D1
Dold, U1
Reichenmiller, HE1
Fellows, WR1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Bioequivalence Study of Sodium Valproate and Valproic Acid Extended Release Tablets in Healthy Human Volunteers[NCT05641649]Phase 416 participants (Anticipated)Interventional2023-08-06Active, not recruiting
A Preliminary Study of the Efficacy and Safety of Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency[NCT01379469]Phase 220 participants (Actual)Interventional2012-01-31Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

13 reviews available for carbamazepine and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016
Drug-induced bile duct injury.
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:4 Pt B

    Topics: Amoxicillin-Potassium Clavulanate Combination; Bile Acids and Salts; Bile Ducts; Biomarkers; Biotran

2018
Role of cytochrome P450-mediated metabolism and involvement of reactive metabolite formations on antiepileptic drug-induced liver injuries.
    The Journal of toxicological sciences, 2018, Volume: 43, Issue:2

    Topics: Animals; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 En

2018
Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions.
    Clinical pharmacology and therapeutics, 2019, Volume: 106, Issue:5

    Topics: Adult; Anaplastic Lymphoma Kinase; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Hyper

2019
Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury.
    Journal of human genetics, 2013, Volume: 58, Issue:6

    Topics: Alleles; Allopurinol; Amoxicillin-Potassium Clavulanate Combination; Azetidines; Benzylamines; Carba

2013
Genetic basis for idiosyncratic reactions to antiepileptic drugs.
    Current opinion in neurology, 2009, Volume: 22, Issue:2

    Topics: Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Epile

2009
[Anticonvulsant hypersensitivity syndrome: an entity to be remembered].
    Gastroenterologia y hepatologia, 2009, Volume: 32, Issue:10

    Topics: Adolescent; Amines; Anemia, Hemolytic; Anticonvulsants; Astrocytoma; Brain Neoplasms; Carbamazepine;

2009
Using genome-wide association studies to identify genes important in serious adverse drug reactions.
    Annual review of pharmacology and toxicology, 2012, Volume: 52

    Topics: Aryl Hydrocarbon Hydroxylases; Carbamazepine; Chemical and Drug Induced Liver Injury; Cytochrome P-4

2012
Extended-release formulations for the treatment of epilepsy.
    CNS drugs, 2007, Volume: 21, Issue:9

    Topics: Animals; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Delayed-Action Prep

2007
Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy.
    Epilepsia, 1991, Volume: 32 Suppl 5

    Topics: Anemia, Aplastic; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Monit

1991
Use of phenytoin and carbamazepine in treatment of epilepsy.
    Neurologic clinics, 1986, Volume: 4, Issue:3

    Topics: Anemia, Aplastic; Carbamazepine; Cerebellar Ataxia; Chemical and Drug Induced Liver Injury; Cognitio

1986
Carbamazepine side effects in children and adults.
    Epilepsia, 1987, Volume: 28 Suppl 3

    Topics: Adult; Agranulocytosis; Anemia, Aplastic; Carbamazepine; Chemical and Drug Induced Liver Injury; Chi

1987
[Hepatitis due to antiepileptic agents].
    Gastroenterologie clinique et biologique, 1985, Volume: 9, Issue:2

    Topics: Acute Disease; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Chemical and Drug Indu

1985

Other Studies

99 other studies available for carbamazepine and Acute Liver Injury, Drug-Induced

ArticleYear
Discovery of N-(2,6-dimethylphenyl)-substituted semicarbazones as anticonvulsants: hybrid pharmacophore-based design.
    Journal of medicinal chemistry, 2005, Oct-06, Volume: 48, Issue:20

    Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Benzamides; Chemical and Drug Induced Liver

2005
N-{[(6-substituted-1,3-benzothiazole-2-yl)amino]carbonothioyl}-2/4-substituted benzamides: synthesis and pharmacological evaluation.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:5

    Topics: Animals; Anticonvulsants; Benzamides; Benzothiazoles; Central Nervous System Depressants; Chemical a

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship;

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
Clinical characteristics of antiepileptic-induced liver injury in patients from the DILIN prospective study.
    Journal of hepatology, 2022, Volume: 76, Issue:4

    Topics: Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Chemical and Drug Ind

2022
Carbamazepine promotes specific stimuli-induced NLRP3 inflammasome activation and causes idiosyncratic liver injury in mice.
    Archives of toxicology, 2019, Volume: 93, Issue:12

    Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbamazepine; C

2019
Carbamazepine induces hepatotoxicity in zebrafish by inhibition of the Wnt/β-catenin signaling pathway.
    Environmental pollution (Barking, Essex : 1987), 2021, May-01, Volume: 276

    Topics: Animals; Carbamazepine; Chemical and Drug Induced Liver Injury; Larva; Wnt Signaling Pathway; Zebraf

2021
Carbamazepine intervention in a patient with efavirenz-induced liver injury.
    AIDS (London, England), 2019, 05-01, Volume: 33, Issue:6

    Topics: Alanine Transaminase; Alkynes; Anti-HIV Agents; Aspartate Aminotransferases; Benzoxazines; Bilirubin

2019
Acute oxcarbazepine-induced hepatotoxicity in a patient susceptible to developing drug-induced liver injury.
    Collegium antropologicum, 2013, Volume: 37, Issue:1

    Topics: Acridines; Carbamazepine; Chemical and Drug Induced Liver Injury; Delivery, Obstetric; Female; Human

2013
Liver: Carbamazepine accelerates liver regeneration in mice after acute injury.
    Nature reviews. Gastroenterology & hepatology, 2013, Volume: 10, Issue:9

    Topics: Analgesics, Non-Narcotic; Animals; Carbamazepine; Chemical and Drug Induced Liver Injury; Disease Mo

2013
Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 140, Issue:1

    Topics: Animals; Apoptosis; Carbamazepine; Chemical and Drug Induced Liver Injury; Diclofenac; Drug Synergis

2014
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
    Journal of applied toxicology : JAT, 2015, Volume: 35, Issue:2

    Topics: Animals; Biomarkers; Carbamazepine; Chemical and Drug Induced Liver Injury; Chlorpromazine; Disease

2015
Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2015, Volume: 43, Issue:7

    Topics: Alanine Transaminase; Animals; Anti-Bacterial Agents; Antifungal Agents; Buthionine Sulfoximine; Car

2015
Case 3: Fever, Vomiting, and Increased Sleepiness in a 4-year-old Girl.
    Pediatrics in review, 2015, Volume: 36, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Child, Preschool; Diagnosis,

2015
High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical's bio-activation with regards hepatotoxicity.
    Toxicology in vitro : an international journal published in association with BIBRA, 2015, Volume: 29, Issue:7

    Topics: Acetaminophen; Amodiaquine; Animals; Carbamazepine; Cell Line, Tumor; Cell Survival; Cells, Cultured

2015
Pathogenetic analyses of carbamazepine-induced liver injury in F344 rats focused on immune- and inflammation-related factors.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2016, Volume: 68, Issue:1

    Topics: Animals; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Disease Models, Ani

2016
HLA-B allele associations with certain drugs are not confirmed in Japanese patients with severe cutaneous drug reactions.
    Acta dermato-venereologica, 2008, Volume: 88, Issue:6

    Topics: Alleles; Allopurinol; Anticonvulsants; Asian People; Carbamazepine; Chemical and Drug Induced Liver

2008
Lamotrigine-associated reversible severe hepatitis: a case report.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2008, Volume: 4, Issue:4

    Topics: Adult; Anticonvulsants; Antimanic Agents; Carbamazepine; Chemical and Drug Induced Liver Injury; Dep

2008
Acetaminophen toxicity with concomitant use of carbamazepine.
    Epileptic disorders : international epilepsy journal with videotape, 2009, Volume: 11, Issue:4

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anticonvulsants; Back Pain; Carbamazepine; Chemical

2009
Severe hepatitis associated with administration of oxcarbazepine.
    Pediatrics international : official journal of the Japan Pediatric Society, 2010, Volume: 52, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Child; Female; Humans; Oxcar

2010
A case of drug-induced hypersensitivity syndrome due to carbamazepine.
    The Bulletin of Tokyo Dental College, 2011, Volume: 52, Issue:3

    Topics: Analgesics, Non-Narcotic; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Eruptions; Dru

2011
[Six cases of spring DRESS].
    Annales de dermatologie et de venereologie, 2012, Volume: 139, Issue:1

    Topics: Acute Kidney Injury; Adult; Aged; Allopurinol; Amoxicillin; Anti-Bacterial Agents; Carbamazepine; Ch

2012
Genetics and the potential for predictive tests in adverse drug reactions.
    Chemical immunology and allergy, 2012, Volume: 97

    Topics: Allopurinol; Anti-Bacterial Agents; Anti-HIV Agents; Anticonvulsants; Antimetabolites; Biomarkers; C

2012
Metabolic activation and inflammation reactions involved in carbamazepine-induced liver injury.
    Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 130, Issue:1

    Topics: Alanine Transaminase; Alprostadil; Animals; Anticonvulsants; Aspartate Aminotransferases; Biomarkers

2012
Mouse precision-cut liver slices as an ex vivo model to study idiosyncratic drug-induced liver injury.
    Chemical research in toxicology, 2012, Sep-17, Volume: 25, Issue:9

    Topics: Animals; Benzodiazepines; Biomarkers; Carbamazepine; Cell Survival; Chemical and Drug Induced Liver

2012
Hepatotoxicity possibly due to paracetamol with carbamazepine.
    Internal medicine journal, 2004, Volume: 34, Issue:7

    Topics: Acetaminophen; Age Factors; Aged; Aged, 80 and over; Carbamazepine; Chemical and Drug Induced Liver

2004
[Erythroderma and hepatitis].
    Anales de pediatria (Barcelona, Spain : 2003), 2004, Volume: 61, Issue:4

    Topics: Anti-Allergic Agents; Carbamazepine; Chemical and Drug Induced Liver Injury; Child, Preschool; Derma

2004
[Gabapentin treatment in a female patient with panic disorder and adverse effects under carbamazepine during benzodiazepine withdrawal].
    Psychiatrische Praxis, 2007, Volume: 34, Issue:2

    Topics: Aged; Alprazolam; Amines; Antimanic Agents; Benzodiazepines; Carbamazepine; Chemical and Drug Induce

2007
Effects of valproate on acylcarnitines in children with epilepsy using ESI-MS/MS.
    Epilepsia, 2007, Volume: 48, Issue:1

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Carnitine; Chemical and Drug Induced Liver Injury; Child

2007
[Hepatotoxicity of carbamazepine: a case of "DRESS syndrome"].
    Gastroenterologie clinique et biologique, 2007, Volume: 31, Issue:2

    Topics: Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity

2007
Glutathione S-transferase M1 null genotype as a risk factor for carbamazepine-induced mild hepatotoxicity.
    Pharmacogenomics, 2007, Volume: 8, Issue:5

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Epilepsy; Female

2007
[Carbamazepine hepatoxicity--a case report].
    Przeglad lekarski, 2007, Volume: 64, Issue:4-5

    Topics: Adolescent; Carbamazepine; Chemical and Drug Induced Liver Injury; Epilepsy; Hepatitis B Surface Ant

2007
Hepatotoxicity of sodium valproate.
    Clinical and experimental neurology, 1983, Volume: 19

    Topics: Adolescent; Adult; Aged; Carbamazepine; Chemical and Drug Induced Liver Injury; Child; Fibrinogen; g

1983
Carbamazepine-induced thrombocytopenia, rash, and hepatic dysfunction.
    Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:9

    Topics: Adult; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; Humans; Thromb

1983
[Toxiderma due to finlepsin].
    Vestnik dermatologii i venerologii, 1983, Issue:9

    Topics: Analgesics; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; Humans; M

1983
Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy.
    Acta neurologica Scandinavica. Supplementum, 1983, Volume: 97

    Topics: Abnormalities, Drug-Induced; Arousal; Benzodiazepinones; Carbamazepine; Chemical and Drug Induced Li

1983
Hepatic toxicity of antiepileptic drugs: a review.
    Acta neurologica Scandinavica. Supplementum, 1983, Volume: 97

    Topics: Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Energy Metabolism; Epilepsy;

1983
[Immuno-allergic side effects induced by the administration of carbamazepine. Case contribution].
    Minerva medica, 1984, Jun-30, Volume: 75, Issue:27

    Topics: Adolescent; Adult; Carbamazepine; Chemical and Drug Induced Liver Injury; Cholangitis; Drug Hypersen

1984
[Two cases of carbamazepine induced hepatitis].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1984, Volume: 73, Issue:8

    Topics: Adult; Carbamazepine; Chemical and Drug Induced Liver Injury; Female; Humans; Liver

1984
[Acute cholestatic hepatitis due to carbamazepine].
    Gastroenterologie clinique et biologique, 1984, Volume: 8, Issue:10

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Female; Humans; Mi

1984
[Hepatitis caused by carbamazepine].
    Medicina clinica, 1984, Dec-08, Volume: 83, Issue:19

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Female; Humans; Middle Aged

1984
[Acute hepatitis due to carbamazepine (Tegretol). Study of a case and review of the literature].
    Gastroenterologie clinique et biologique, 1984, Volume: 8, Issue:1

    Topics: Acute Disease; Adult; Carbamazepine; Chemical and Drug Induced Liver Injury; Female; Humans; Liver

1984
[Fatal liver disorder during treatment with sodium valproate and carbamazepine].
    Archives francaises de pediatrie, 1982, Volume: 39, Issue:9

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Child; Drug Therapy, Combination; Epilepsies,

1982
Carbamazepine-induced liver injury.
    Southern medical journal, 1983, Volume: 76, Issue:5

    Topics: Adult; Biopsy; Carbamazepine; Chemical and Drug Induced Liver Injury; Female; Hepatitis; Humans; Liv

1983
[Carbamazepine and methyldopa: a hepatotoxic combination?].
    Medicina clinica, 1983, Jun-11, Volume: 81, Issue:1

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Interactions; Female; Humans; Methyldopa

1983
Granulomatous hepatitis secondary to carbamazepine.
    Annals of internal medicine, 1981, Volume: 95, Issue:1

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Cholangitis; Granuloma; Humans; Liver; Male;

1981
Granulomatous hepatitis associated with carbamazepine therapy.
    The American journal of medicine, 1981, Volume: 71, Issue:4

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Granuloma; Humans; Liver; Male; Middle Aged

1981
Fatal carbamazepine-associated hepatitis. Report of two cases.
    Acta medica Scandinavica, 1981, Volume: 210, Issue:4

    Topics: Adult; Alcoholism; Carbamazepine; Chemical and Drug Induced Liver Injury; Epilepsy; Female; Humans;

1981
Granulomatous hepatitis in a patient receiving carbamazepine.
    Acta medica Scandinavica, 1980, Volume: 208, Issue:4

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Female; Granuloma; Humans; Liver; Middle Aged

1980
A comparative study of serum F protein and other liver function tests as an index of hepatocellular damage in epileptic patients.
    Acta neurologica Scandinavica, 1994, Volume: 89, Issue:4

    Topics: Adult; Alkaline Phosphatase; Anticonvulsants; Aspartate Aminotransferases; Carbamazepine; Chemical a

1994
A reversible parkinsonian syndrome and hepatotoxcity following addition of carbamazepine to sodium valproate.
    Australian and New Zealand journal of medicine, 1994, Volume: 24, Issue:4

    Topics: Aged; Carbamazepine; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Interactions; Drug Th

1994
[Carbamazepine poisoning: protracted course with development of intestinal atony and hepatic toxicity].
    Wiener klinische Wochenschrift, 1994, Volume: 106, Issue:1

    Topics: Adult; Bipolar Disorder; Carbamazepine; Chemical and Drug Induced Liver Injury; Coma; Drug Overdose;

1994
Carbamazepine-induced hepatitis in a patient with cervical myelopathy.
    Archives of physical medicine and rehabilitation, 1996, Volume: 77, Issue:3

    Topics: Aged; Carbamazepine; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Eruptions; Eosinophil

1996
Case of ageusia from a variety of causes.
    The Journal of laryngology and otology, 1996, Volume: 110, Issue:6

    Topics: Adult; Ageusia; Anorexia; Carbamazepine; Chemical and Drug Induced Liver Injury; Female; Humans; Liv

1996
Recreational overdosage of carbamazepine in Paisley drug abusers.
    Scottish medical journal, 1997, Volume: 42, Issue:3

    Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Carbamazepine; Chemical and Drug Induced Liver In

1997
Carbamazepine-induced pseudolymphoma with CD-30 positive cells.
    Journal of the American Academy of Dermatology, 1998, Volume: 38, Issue:5 Pt 2

    Topics: Adult; Anticonvulsants; Antigens, CD20; Biopsy; Carbamazepine; CD3 Complex; Chemical and Drug Induce

1998
Suspected carbamazepine-induced hepatotoxicity.
    Pharmacotherapy, 1999, Volume: 19, Issue:2

    Topics: Adverse Drug Reaction Reporting Systems; Anticonvulsants; Carbamazepine; Chemical and Drug Induced L

1999
Carbamazepine, hepatotoxicity, organic solvents, and paints.
    Seizure, 1999, Volume: 8, Issue:4

    Topics: Alcohol Drinking; Anticonvulsants; Bipolar Disorder; Carbamazepine; Chemical and Drug Induced Liver

1999
[Carbamazepine-induced hepatitis. A case report].
    Acta gastroenterologica Latinoamericana, 1999, Volume: 29, Issue:4

    Topics: Adrenal Cortex Hormones; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Hum

1999
Potential interaction between ritonavir and carbamazepine.
    Pharmacotherapy, 2000, Volume: 20, Issue:7

    Topics: Adult; Anti-HIV Agents; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug

2000
[Carbamazepine-induced hepatitis].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2000, Oct-10, Volume: 120, Issue:24

    Topics: Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Female; Humans; Liver

2000
[A case of acute renal failure and liver dysfunction induced by carbamazepine(CBZ)].
    Nihon Jinzo Gakkai shi, 2001, Volume: 43, Issue:4

    Topics: Acute Kidney Injury; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Female;

2001
[DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome after sulfasalazine and carmazepine: report of two cases].
    La Revue de medecine interne, 2001, Volume: 22, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants

2001
Non-alcoholic steatohepatitis induced by carbamazepine and variegate porphyria.
    European journal of gastroenterology & hepatology, 2001, Volume: 13, Issue:8

    Topics: Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Diagnosis, Differenti

2001
Neonatal cholestatic hepatitis from carbamazepine exposure during pregnancy and breast feeding.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:4

    Topics: Breast Feeding; Carbamazepine; Chemical and Drug Induced Liver Injury; Cholestasis; Epilepsy; Female

2002
[Drug-induced hepatitis. Review and report of a case caused by carbamazepine (Tegretol)].
    Ugeskrift for laeger, 1979, Nov-12, Volume: 141, Issue:46

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Humans; Liver; Male; Middle Aged

1979
Liver functions in children receiving carbamazepine.
    The Journal of pediatrics, 1978, Volume: 93, Issue:5

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Function Tests

1978
Fatal carbamazepine hepatitis.
    The Journal of pediatrics, 1977, Volume: 91, Issue:4

    Topics: Adolescent; Carbamazepine; Chemical and Drug Induced Liver Injury; Epilepsy; Female; Humans

1977
Severe hepatorenal failure in a child receiving carbamazepine and erythromycin.
    European journal of pediatrics, 1992, Volume: 151, Issue:9

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Child; Erythromycin; Humans; Kidney Tubular N

1992
Detection of an autoantibody directed against human liver microsomal protein in a patient with carbamazepine hypersensitivity.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:2

    Topics: Adolescent; Animals; Autoantibodies; Carbamazepine; Cell Death; Chemical and Drug Induced Liver Inju

1992
Effects of acute carbamazepine administration on haem metabolism in rat liver.
    Biochemical pharmacology, 1992, Apr-01, Volume: 43, Issue:7

    Topics: 5-Aminolevulinate Synthetase; Allopurinol; Animals; Carbamazepine; Chemical and Drug Induced Liver I

1992
A case of photosensitivity and contact allergy to systemic tricyclic drugs, with unusual features.
    Contact dermatitis, 1991, Volume: 24, Issue:4

    Topics: Adult; Carbamazepine; Chemical and Drug Induced Liver Injury; Clomipramine; Cross Reactions; Dermati

1991
Liver damage in long-term anticonvulsant therapy: a serological and histological study.
    The Quarterly journal of medicine, 1991, Volume: 79, Issue:288

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Combinatio

1991
[Carbamazepine-associated hepatitis].
    Harefuah, 1990, Dec-16, Volume: 119, Issue:12

    Topics: Aged; Carbamazepine; Chemical and Drug Induced Liver Injury; Female; Humans

1990
[Mononucleosis syndrome with hypersensitivity hepatitis following carbamazepine administration].
    Zeitschrift fur arztliche Fortbildung, 1990, Volume: 84, Issue:11

    Topics: Adult; Carbamazepine; Chemical and Drug Induced Liver Injury; Depressive Disorder; Diagnosis, Differ

1990
Transient cholestatic hepatitis in a neonate associated with carbamazepine exposure during pregnancy and breast-feeding.
    European journal of pediatrics, 1990, Volume: 150, Issue:2

    Topics: Breast Feeding; Carbamazepine; Chemical and Drug Induced Liver Injury; Epilepsy; Female; Humans; Inf

1990
Epidemiology of adverse reactions to carbamazepine as seen in a spontaneous reporting system.
    Acta neurologica Scandinavica, 1990, Volume: 81, Issue:2

    Topics: Age Factors; Carbamazepine; Chemical and Drug Induced Liver Injury; Epilepsy; Female; Hematologic Di

1990
Phenobarbital hepatotoxicity in an 8-month-old infant.
    Journal of hepatology, 1990, Volume: 10, Issue:2

    Topics: Carbamazepine; Cell Survival; Chemical and Drug Induced Liver Injury; Humans; Infant; Lymphocytes; M

1990
Acute liver failure induced by carbamazepine.
    Archives of disease in childhood, 1990, Volume: 65, Issue:3

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Child; Female; Humans; Liver; Liver Diseases;

1990
The influence of long-term anticonvulsant therapy with diphenylhydantoin and carbamazepine on serum gamma-glutamyltransferase, aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase.
    European archives of psychiatry and neurological sciences, 1988, Volume: 237, Issue:5

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Carbamazepine; Chemi

1988
Three cases of carbamazepine toxicity.
    The American journal of psychiatry, 1985, Volume: 142, Issue:8

    Topics: Adult; Anemia, Aplastic; Bipolar Disorder; Carbamazepine; Chemical and Drug Induced Liver Injury; Dr

1985
A case of hepatitis associated with carbamazepine therapy.
    European journal of pediatrics, 1988, Volume: 147, Issue:6

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Child; Female; Humans

1988
Anticonvulsant-induced liver damage.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:5

    Topics: Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Clonazepam; Humans; L

1988
Carbamazepine induced granulomatous hepatitis.
    The New Zealand medical journal, 1986, Mar-12, Volume: 99, Issue:797

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Epilepsy, Temporal Lobe; Granuloma; Humans; M

1986
[Granulomatous hepatitis caused by carbamazepine].
    Revista clinica espanola, 1987, Volume: 181, Issue:2

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Female; Granuloma; Humans; Middle Aged

1987
Hepatic reaction to carbamazepine.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:4

    Topics: Adult; Carbamazepine; Chemical and Drug Induced Liver Injury; Humans; Liver; Male

1986
The side effects of carbamazepine.
    The American journal of psychiatry, 1986, Volume: 143, Issue:3

    Topics: Anemia, Aplastic; Bipolar Disorder; Carbamazepine; Chemical and Drug Induced Liver Injury; Humans; P

1986
[Hepatitis caused by carbamazepine].
    Medicina clinica, 1985, Apr-06, Volume: 84, Issue:13

    Topics: Carbamazepine; Chemical and Drug Induced Liver Injury; Humans

1985
Acute hepatitis in a patient treated with carbamazepine.
    Journal of neurology, 1985, Volume: 232, Issue:5

    Topics: Acute Disease; Carbamazepine; Chemical and Drug Induced Liver Injury; Child, Preschool; Epilepsy; Hu

1985
Diphenylhydantoin.
    The Medical letter on drugs and therapeutics, 1971, Jun-11, Volume: 13, Issue:12

    Topics: Affective Symptoms; Arrhythmias, Cardiac; Ataxia; Carbamazepine; Central Nervous System Diseases; Ch

1971
[Acute hepatic cell damage by simultaneous administration of isonicotinic acid hydrazide and antiepileptic agents in humans, (diphenylhydantoin or carbamazepin)].
    Die Medizinische Welt, 1969, Jan-04, Volume: 1

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Dibenzaze

1969
A case of aplastic anemia and pancytopenia with tegretol therapy.
    Headache, 1969, Volume: 9, Issue:1

    Topics: Anemia, Aplastic; Carbamazepine; Chemical and Drug Induced Liver Injury; Dibenzazepines; Humans; Mal

1969