Page last updated: 2024-10-24

carbamazepine and Acquired Neuromyotonia

carbamazepine has been researched along with Acquired Neuromyotonia in 31 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Research Excerpts

ExcerptRelevanceReference
" Notably, we demonstrated the positive effects of carbamazepine in treating muscle stiffness and cramps of ARAN-NM."5.22A novel mutation in HINT1 gene causes autosomal recessive axonal neuropathy with neuromyotonia, effective treatment with carbamazepine and review of the literature. ( Lin, P; Lv, X; Wang, G; Xu, L; Yan, C; Zhang, D, 2022)
"The terms "Isaac Syndrome" and "Acquired Neuromyotonia" were used."3.01Systematic Review of the Clinical Characteristics and Management of Isaac Syndrome. ( Abouainain, Y; Al-Chalabi, M; Eid, J; Hegde, P; Keener, M; Moore, SR; Parvez, H; Saleem, S; Sheikh, A, 2023)
"Treatment with carbamazepine remains first-line therapy, although other membrane stabilizing agents and surgical interventions can be effective."2.82Ocular neuromyotonia: a review of diagnosis and treatment. ( Lee, MS; Lee, SK, 2022)
"Ocular neuromyotonia (ONM) is a rare neurogenic disorder of ocular motility."2.45[Ocular neuromyotonia--clinical appearance and thoughts on pathogenesis]. ( Salchow, D; Wermund, TK, 2009)
"Ocular neuromyotonia is a rare ocular motility disorder characterized by involuntary contractions of one or several ocular motor muscles."2.43[Ocular neuromyotonia]. ( Gräf, M; Koop, G, 2006)
"The first report of oculomotor neuromyotonia (ONM) in a child induced by thyroid peroxidase antibodies (anti-TPO) in the absence of thyroid eye disease (TED)."1.72Thyroid peroxidase antibodies may induce demyelination and oculomotor neuromyotonia in the absence of thyroid eye disease. ( Bjelos, M; Bulat, S; Busic, I; Curic, A; Kuzmanovic Elabjer, B, 2022)
"Hemifacial spasm is diagnosed on a clinical base, with certain atypical features alerting the physician for mimics."1.62Post-Irradiation Facial Neuromyotonia/Myokymia: A Hemifacial Spasm Mimic. ( Koelman, JHTM; Swinnen, BEKS; van Rootselaar, AF, 2021)
"Ocular neuromyotonia is an unusual condition in which sustained, undesired contraction of one or more extraocular muscles occurs after normal muscle activation."1.39Partial third nerve palsy and ocular neuromyotonia from displacement of posterior communicating artery detected by high-resolution MRI. ( Blitz, AM; Cruz, FM; Subramanian, PS, 2013)
"It is characterized by symptomatic diplopia for the duration of the contraction and occurs either spontaneously or after a sustained eccentric gaze."1.39Oculomotor neuromyotonia with lid ptosis on abduction. ( Chang, MH; Kim, SB; Kyung, SE; Oh, SY, 2013)
"ADMS rats dominantly exhibited myokymia, neuromyotonia and generalized tonic-clonic seizures."1.38Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures. ( Baulac, S; Ishida, S; Kaneko, S; Kuwamura, M; Mashimo, T; Nishio, T; Ohno, Y; Sakamoto, Y; Serikawa, T; Takizawa, A, 2012)
"Carbamazepine treatment was only partially and transiently effective."1.36Serial monitoring of basal metabolic rate for therapeutic evaluation in an Isaacs' syndrome patient with chronic fluctuating symptoms. ( Hayashi, Y; Hozumi, I; Inuzuka, T; Kimura, A; Sakurai, T; Tanaka, Y; Watanabe, N; Yamada, M, 2010)
"She was diagnosed with ocular neuromyotonia and successfully treated with oral carbamazepine."1.35Ocular neuromyotonia in a 15-year-old girl after radiation therapy. ( Aroichane, M; de Saint Sardos, A; Ospina, LH; Vincent, A, 2008)
"This report describes Isaacs' syndrome in a child, in whom the diagnosis was made by clinical features of acquired, spontaneous muscle overactivity and typical electromyographic findings."1.35Acquired neuromyotonia in childhood: case report and review. ( Barros, G; Gonzalez, G; Nuñez, A; Russi, ME; Scavone, C, 2008)
"Ocular neuromyotonia is a rare disturbance of ocular motility, characterized by paroxysmal monocular involuntary spasms of one or more extraocular muscles supplied by the third, fourth or sixth cranial nerves."1.34[Case of ocular neuromyotonia with transient and gaze-induced diplopia]. ( Hayashi, H; Isozaki, E; Kuroda, M; Matsubara, S; Yoshida, H, 2007)
"Gabapentin thus appears to be an effective treatment for Isaacs' syndrome."1.33Isaacs' syndrome: clinical and electrophysiological response to gabapentin. ( Dhand, UK, 2006)
"Treatment with carbamazepine resulted in substantial improvement of the symptoms within 7 days."1.33Acquired neuromyotonia (Isaacs' syndrome): a case report with autonomic physiologic studies. ( Mitrabhakdi, E; Phanthumchinda, K; Sukajintanakarn, D, 2006)
"Ocular neuromyotonia is a rare clinical entity, which is characterized by spontaneous spasm of ocular muscles resulting in paroxysmal diplopia and strabismus."1.32Ocular neuromyotonia: a case report. ( Ilhan, S; Yürüten, B, 2003)
"Carbamazepine therapy was tried in 12 additional patients to determine whether the neurologic effects might be relieved."1.31Acute oxaliplatin-induced peripheral nerve hyperexcitability. ( Floeter, MK; Grem, JL; Lehky, T; Quinn, MG; Thomas, RR; Wilson, RH, 2002)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (45.16)29.6817
2010's11 (35.48)24.3611
2020's6 (19.35)2.80

Authors

AuthorsStudies
Swinnen, BEKS1
Koelman, JHTM1
van Rootselaar, AF1
Xu, L1
Wang, G1
Lv, X1
Zhang, D1
Yan, C1
Lin, P1
Bjelos, M1
Curic, A1
Kuzmanovic Elabjer, B1
Busic, I1
Bulat, S1
Lee, SK1
Lee, MS1
Al-Chalabi, M1
Hegde, P1
Moore, SR1
Abouainain, Y1
Keener, M1
Parvez, H1
Eid, J1
Saleem, S1
Sheikh, A1
Rivera, CZ1
Solomon, AM1
Francis, CE1
Grosinger, A1
Chen, JJ1
Bhatti, MT1
Morales-Briceño, H1
Perez, JR1
Balint, B1
Fung, VSC1
Roper-Hall, G1
Cruz, OA1
Espinoza, GM1
Chung, SM1
Gadoth, A1
Kipervasser, S1
Korczyn, AD1
Neufeld, MY1
Kesler, A1
Cruz, FM1
Blitz, AM1
Subramanian, PS1
Storey, PP1
Kim, EL1
Patel, V1
de Saint Sardos, A1
Vincent, A1
Aroichane, M1
Ospina, LH1
Wermund, TK1
Salchow, D1
Hayashi, Y1
Kimura, A1
Watanabe, N1
Yamada, M1
Sakurai, T1
Tanaka, Y1
Hozumi, I1
Inuzuka, T1
Weston, K1
Bush, K1
Afshar, F1
Rowley, S1
Weiss, N1
Behin, A1
Psimaras, D1
Delattre, JY1
Ishida, S1
Sakamoto, Y1
Nishio, T1
Baulac, S1
Kuwamura, M1
Ohno, Y1
Takizawa, A1
Kaneko, S1
Serikawa, T1
Mashimo, T1
Kim, SB1
Oh, SY1
Chang, MH1
Kyung, SE1
Yürüten, B1
Ilhan, S1
Banks, MC1
Caruso, PA1
Lessell, S1
Koop, G1
Gräf, M1
Jacob, M1
Vighetto, A1
Bernard, M1
Tilikete, C1
Dhand, UK1
Sukajintanakarn, D1
Mitrabhakdi, E1
Phanthumchinda, K1
O'Sullivan, SS1
Mullins, GM1
Neligan, A1
McNamara, B1
Galvin, RJ1
Kuroda, M1
Isozaki, E1
Matsubara, S1
Yoshida, H1
Hayashi, H1
Gonzalez, G1
Barros, G1
Russi, ME1
Nuñez, A1
Scavone, C1
Otsuka, R1
Arimura, K1
Osame, M1
Wilson, RH1
Lehky, T1
Thomas, RR1
Quinn, MG1
Floeter, MK1
Grem, JL1
Tindle, HA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Study of Oxaliplatin in Combination With Capecitabine in Adult Cancer Patients[NCT00019773]Phase 10 participants Interventional1999-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for carbamazepine and Acquired Neuromyotonia

ArticleYear
A novel mutation in HINT1 gene causes autosomal recessive axonal neuropathy with neuromyotonia, effective treatment with carbamazepine and review of the literature.
    Acta neurologica Belgica, 2022, Volume: 122, Issue:5

    Topics: Adolescent; Carbamazepine; Charcot-Marie-Tooth Disease; Histidine; Humans; Isaacs Syndrome; Muscle C

2022
Ocular neuromyotonia: a review of diagnosis and treatment.
    Current opinion in ophthalmology, 2022, Nov-01, Volume: 33, Issue:6

    Topics: Adult; Carbamazepine; Child; Diplopia; Excipients; Humans; Isaacs Syndrome; Ocular Motility Disorder

2022
Systematic Review of the Clinical Characteristics and Management of Isaac Syndrome.
    Journal of clinical neuromuscular disease, 2023, Dec-01, Volume: 25, Issue:2

    Topics: Anticonvulsants; Autoantibodies; Carbamazepine; Female; Humans; Isaacs Syndrome; Male; Middle Aged;

2023
[Ocular neuromyotonia--clinical appearance and thoughts on pathogenesis].
    Klinische Monatsblatter fur Augenheilkunde, 2009, Volume: 226, Issue:11

    Topics: Animals; Anticonvulsants; Axons; Carbamazepine; Diplopia; Electromyography; Interneurons; Isaacs Syn

2009
[Ocular neuromyotonia].
    Klinische Monatsblatter fur Augenheilkunde, 2006, Volume: 223, Issue:3

    Topics: Abducens Nerve Diseases; Carbamazepine; Combined Modality Therapy; Diplopia; Female; Humans; Isaacs

2006
[Isaacs' syndrome].
    Ryoikibetsu shokogun shirizu, 2000, Issue:31

    Topics: Animals; Anticonvulsants; Autoantibodies; Carbamazepine; Diagnosis, Differential; Humans; Isaacs Syn

2000

Other Studies

25 other studies available for carbamazepine and Acquired Neuromyotonia

ArticleYear
Post-Irradiation Facial Neuromyotonia/Myokymia: A Hemifacial Spasm Mimic.
    Tremor and other hyperkinetic movements (New York, N.Y.), 2021, Volume: 11

    Topics: Carbamazepine; Facial Nerve Diseases; Hemifacial Spasm; Humans; Isaacs Syndrome; Myokymia

2021
Thyroid peroxidase antibodies may induce demyelination and oculomotor neuromyotonia in the absence of thyroid eye disease.
    Neuro endocrinology letters, 2022, Jun-07, Volume: 43, Issue:2

    Topics: Adolescent; Adult; Carbamazepine; Child; Demyelinating Diseases; Female; Graves Ophthalmopathy; Huma

2022
Case of Facial Neuromyotonia.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2021, 03-01, Volume: 41, Issue:1

    Topics: Aged; Anticonvulsants; Carbamazepine; Facial Nerve Diseases; Female; Humans; Isaacs Syndrome; Magnet

2021
Gaze-Provoked Exotropia in a Young Woman.
    JAMA ophthalmology, 2019, Jul-01, Volume: 137, Issue:7

    Topics: Abducens Nerve Diseases; Adult; Carbamazepine; Diplopia; Exotropia; Eye Movements; Female; Fixation,

2019
Teaching Video NeuroImages: Cold-induced laryngeal pseudomyotonia in Isaacs syndrome.
    Neurology, 2019, 06-04, Volume: 92, Issue:23

    Topics: Adult; Analgesics, Non-Narcotic; Carbamazepine; Cold Temperature; Electromyography; Humans; Immunogl

2019
Cyclic (alternate day) vertical deviation--possible forme fruste of ocular neuromyotonia.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2013, Volume: 17, Issue:3

    Topics: Carbamazepine; Diplopia; Exophthalmos; Female; Humans; Isaacs Syndrome; Male; Middle Aged; Oculomoto

2013
Acquired oculomotor nerve paresis with cyclic spasms in a young woman, a rare subtype of neuromyotonia.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2013, Volume: 33, Issue:3

    Topics: Adult; Anticonvulsants; Carbamazepine; Cerebellar Neoplasms; Female; Humans; Isaacs Syndrome; Medull

2013
Partial third nerve palsy and ocular neuromyotonia from displacement of posterior communicating artery detected by high-resolution MRI.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2013, Volume: 33, Issue:3

    Topics: Aged; Anticonvulsants; Carbamazepine; Circle of Willis; Diplopia; Female; Humans; Isaacs Syndrome; M

2013
Ptosis, Miosis, and Intermittent Esotropia Following Pituitary Adenoma Resection.
    JAMA ophthalmology, 2016, 08-01, Volume: 134, Issue:8

    Topics: Adenoma; Analgesics, Non-Narcotic; Blepharoptosis; Carbamazepine; Esotropia; Female; Humans; Isaacs

2016
Ocular neuromyotonia in a 15-year-old girl after radiation therapy.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2008, Volume: 12, Issue:6

    Topics: Adolescent; Autoantibodies; Carbamazepine; Cerebellar Neoplasms; Combined Modality Therapy; Cranial

2008
Serial monitoring of basal metabolic rate for therapeutic evaluation in an Isaacs' syndrome patient with chronic fluctuating symptoms.
    Internal medicine (Tokyo, Japan), 2010, Volume: 49, Issue:5

    Topics: Anticonvulsants; Basal Metabolism; Breath Tests; Carbamazepine; Electromyography; Humans; Immunoglob

2010
Can he fix it? Yes, he can!
    BMJ (Clinical research ed.), 2010, Dec-08, Volume: 341

    Topics: Aged; Anticonvulsants; Carbamazepine; Diplopia; Eye Protective Devices; Female; Humans; Isaacs Syndr

2010
Postirradiation neuromyotonia of spinal accessory nerves.
    Neurology, 2011, Mar-29, Volume: 76, Issue:13

    Topics: Accessory Nerve; Aged; Anticonvulsants; Carbamazepine; Electromyography; Humans; Isaacs Syndrome; Ma

2011
Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures.
    Brain research, 2012, Jan-30, Volume: 1435

    Topics: Animals; Antiemetics; Biophysical Phenomena; Biotinylation; Body Weight; Carbamazepine; Cells, Cultu

2012
Oculomotor neuromyotonia with lid ptosis on abduction.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2013, Volume: 17, Issue:1

    Topics: Analgesics, Non-Narcotic; Blepharoptosis; Carbamazepine; Diplopia; Humans; Isaacs Syndrome; Male; Mi

2013
Ocular neuromyotonia: a case report.
    Clinical neurology and neurosurgery, 2003, Volume: 105, Issue:2

    Topics: Adult; Anticonvulsants; Carbamazepine; Diplopia; Female; Humans; Isaacs Syndrome; Oculomotor Nerve D

2003
Midbrain-thalamic ocular neuromyotonia.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2005, Volume: 123, Issue:1

    Topics: Adult; Anticonvulsants; Carbamazepine; Diplopia; Dizziness; Humans; Isaacs Syndrome; Magnetic Resona

2005
Ocular neuromyotonia secondary to a cavernous sinus meningioma.
    Neurology, 2006, May-23, Volume: 66, Issue:10

    Topics: Acetazolamide; Adult; Carbamazepine; Cavernous Sinus; Clonazepam; Diplopia; Esotropia; Female; Human

2006
Isaacs' syndrome: clinical and electrophysiological response to gabapentin.
    Muscle & nerve, 2006, Volume: 34, Issue:5

    Topics: Action Potentials; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Electromyogr

2006
Acquired neuromyotonia (Isaacs' syndrome): a case report with autonomic physiologic studies.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2006, Volume: 89, Issue:8

    Topics: Adolescent; Antibodies; Anticonvulsants; Carbamazepine; Electromyography; Humans; Isaacs Syndrome; M

2006
Acquired generalised neuromyotonia, cutaneous lupus erythematosus and alopecia areata in a patient with myasthenia gravis.
    Clinical neurology and neurosurgery, 2007, Volume: 109, Issue:4

    Topics: Alopecia Areata; Antibodies, Antinuclear; Autoantibodies; Autoimmune Diseases; Carbamazepine; Female

2007
[Case of ocular neuromyotonia with transient and gaze-induced diplopia].
    Rinsho shinkeigaku = Clinical neurology, 2007, Volume: 47, Issue:6

    Topics: Aged; Carbamazepine; Diplopia; Fixation, Ocular; Humans; Isaacs Syndrome; Male; Ocular Motility Diso

2007
Acquired neuromyotonia in childhood: case report and review.
    Pediatric neurology, 2008, Volume: 38, Issue:1

    Topics: Adolescent; Age Factors; Anticonvulsants; Autoantibodies; Carbamazepine; Diagnosis, Differential; El

2008
Acute oxaliplatin-induced peripheral nerve hyperexcitability.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Apr-01, Volume: 20, Issue:7

    Topics: Acute Disease; Aged; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Pr

2002
Why etiology matters.
    Medical economics, 2002, Apr-12, Volume: 79, Issue:7

    Topics: Adult; Analgesics, Non-Narcotic; Carbamazepine; Diagnosis, Differential; Family Practice; Headache;

2002