Page last updated: 2024-10-24

carbamazepine and Abnormalities, Drug-Induced

carbamazepine has been researched along with Abnormalities, Drug-Induced in 123 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
"Lamotrigine is used in pregnancy to control epilepsy and mood disorders."8.95Pregnancy Outcomes Following In Utero Exposure to Lamotrigine: A Systematic Review and Meta-Analysis. ( Adams-Webber, T; Barzilay, E; Leibson, T; Nulman, I; Pariente, G; Shulman, T, 2017)
" In this review, the safety of the newer AED oxcarbazepine during pregnancy is assessed based on published pregnancy outcome data."8.82Safety of the newer antiepileptic drug oxcarbazepine during pregnancy. ( Montouris, G, 2005)
"We report a stillborn, GA/LMP = 37 weeks, delivered by an epileptic woman, who received in the first four months of pregnancy phenobarbital (PH) 0."7.79Sirenomelia after phenobarbital and carbamazepine therapy in pregnancy. ( Brailoiu, CG; Cernea, N; Tica, AA; Tica, OS; Tica, VI, 2013)
"Similar to valproic acid, carbamazepine increases the risk of neural tube defects; however, it does not increase the risk of other malformations."7.78Is carbamazepine safe to take during pregnancy? ( Koren, G; Matlow, J, 2012)
" The mothers of all for children were treated with carbamazepine during pregnancy."7.70Eye malformations associated with treatment with carbamazepine during pregnancy. ( Jones, RB; Sutcliffe, AG; Woodruff, G, 1998)
" A metastatic neuroblastoma was detected immediately after birth in a boy born to a 26 year old woman with bipolar disorder, who received carbamazepine (400 mg/day) all through her pregnancy."7.70Congenital neuroblastoma in a boy born to a woman with bipolar disorder treated with carbamazepine during pregnancy. ( Araujo, H; Baptista, T; Hernández, L; Rada, P, 1998)
"Carbamazepine and water were given by gastric gavage throughout gestational period."5.42Teratogenic effect of Carbamazepine use during pregnancy in the mice. ( El-Kenawy, Ael-M; Elshama, SS; Osman, HE, 2015)
"Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment."5.27Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983)
"Lamotrigine is used in pregnancy to control epilepsy and mood disorders."4.95Pregnancy Outcomes Following In Utero Exposure to Lamotrigine: A Systematic Review and Meta-Analysis. ( Adams-Webber, T; Barzilay, E; Leibson, T; Nulman, I; Pariente, G; Shulman, T, 2017)
"A systematic search was carried out of electronic databases, reference books and other sources for original research studies which examined the effects of commonly used mood stabilizers (sodium valproate, carbamazepine, lamotrigine and lithium carbonate) on pregnancy outcomes."4.86Mood stabilizers in pregnancy: a systematic review. ( Buist, A; Galbally, M; Roberts, M, 2010)
"To identify specific major congenital malformations associated with use of carbamazepine in the first trimester of pregnancy."4.86Intrauterine exposure to carbamazepine and specific congenital malformations: systematic review and case-control study. ( de Jong-van den Berg, L; Dolk, H; Garne, E; Jentink, J; Loane, MA; Morris, JK; Wellesley, D, 2010)
" In this review, the safety of the newer AED oxcarbazepine during pregnancy is assessed based on published pregnancy outcome data."4.82Safety of the newer antiepileptic drug oxcarbazepine during pregnancy. ( Montouris, G, 2005)
"05) of an increased hazard of fetal malformation associated with exposure to valproate, carbamazepine, topiramate, zonisamide, and with conception after assisted fertilization, but a reduced hazard in the offspring of women who continued to smoke during pregnancy."4.31Specific fetal malformations following intrauterine exposure to antiseizure medication. ( Eadie, M; Graham, J; Hitchcock, A; Lander, C; O'Brien, T; Perucca, P; Vajda, F, 2023)
" Here we provide updated results from the UK Epilepsy and Pregnancy Register of the risk of MCMs after monotherapy exposure to valproate, carbamazepine and lamotrigine."3.80Malformation risks of antiepileptic drug monotherapies in pregnancy: updated results from the UK and Ireland Epilepsy and Pregnancy Registers. ( Campbell, E; Craig, J; Delanty, N; Hunt, SJ; Irwin, B; Kennedy, F; Liggan, B; Morrison, PJ; Morrow, J; Parsons, L; Russell, A; Smithson, WH, 2014)
"We report a stillborn, GA/LMP = 37 weeks, delivered by an epileptic woman, who received in the first four months of pregnancy phenobarbital (PH) 0."3.79Sirenomelia after phenobarbital and carbamazepine therapy in pregnancy. ( Brailoiu, CG; Cernea, N; Tica, AA; Tica, OS; Tica, VI, 2013)
"Similar to valproic acid, carbamazepine increases the risk of neural tube defects; however, it does not increase the risk of other malformations."3.78Is carbamazepine safe to take during pregnancy? ( Koren, G; Matlow, J, 2012)
"Based on epidemiological data it is advised to whenever possible avoid valproic acid during pregnancy."3.78Economic evaluation of anti-epileptic drug therapies with specific focus on teratogenic outcomes. ( Boersma, C; de Jong-van den Berg, LT; Jentink, J; Postma, MJ, 2012)
"Valproic acid, which current guidelines suggest should be avoided in pregnancy, was most notable in terms of strength and breadth of its associations."3.77Use of antiepileptic medications in pregnancy in relation to risks of birth defects. ( Ahrens, KA; Anderka, MT; Bosco, JL; Gilboa, SM; Holmes, LB; Mitchell, AA; Werler, MM, 2011)
"To determine the frequency of malformations among infants born to women who had taken lamotrigine or carbamazepine as part of polytherapy during the first trimester of pregnancy."3.77Fetal effects of anticonvulsant polytherapies: different risks from different drug combinations. ( Hernandez-Diaz, S; Holmes, LB; Mittendorf, R; Shen, A; Smith, CR, 2011)
"(1) Numerous follow-up studies of pregnancies in women with epilepsy show that valproic acid is more teratogenic than other antiepileptics."3.75Valproic acid: long-term effects on children exposed in utero. ( , 2009)
" We point out that during the pregnancy 4 of these 5 women with epilepsy had taken valproates, and the other one--carbamazepine."3.75[Fetal malformations in women with epilepsy]. ( Bozhinov, P; Bozhinova, C; Markova, C, 2009)
"An increased risk for isolated CL/P was found in cases born to mothers treated with amoxicillin, phenytoin, oxprenolol, and thiethylperazine during the second and third month of pregnancy, i."3.74Drug treatment during pregnancy and isolated orofacial clefts in hungary. ( Czeizel, AE; Métneki, J; Puhó, EH; Szunyogh, M, 2007)
" By contrast, offspring of rats exposed to carbamazepine (which at the dose used produced low plasma concentrations) or to generalized convulsive seizures showed no clear-cut evidence of dysplasias."3.74Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias. ( Ben-Ari, Y; Depaulis, A; Jorquera, I; Manent, JB; Mazzucchelli, I; Perucca, E; Represa, A, 2007)
"Children exposed during pregnancy to the anticonvulsant drugs phenytoin, phenobarbital, and carbamazepine as monotherapy and polytherapy have an increased frequency of midface and digit hypoplasia."3.73The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs. ( Coull, BA; Dorfman, J; Holmes, LB; Rosenberger, PB, 2005)
"We selected all subjects who enrolled in the California Teratogen Information Service (CTIS) pregnancy outcome study for prenatal exposure to carbamazepine or valproic acid between 1990 and 1997 and who received prenatal care through Kaiser Permanente of Southern California (n = 13)."3.71Selection bias in Teratology Information Service pregnancy outcome studies. ( Chambers, CD; Johnson, KA; Jones, KL; Weber, PA, 2001)
" A metastatic neuroblastoma was detected immediately after birth in a boy born to a 26 year old woman with bipolar disorder, who received carbamazepine (400 mg/day) all through her pregnancy."3.70Congenital neuroblastoma in a boy born to a woman with bipolar disorder treated with carbamazepine during pregnancy. ( Araujo, H; Baptista, T; Hernández, L; Rada, P, 1998)
" The mothers of all for children were treated with carbamazepine during pregnancy."3.70Eye malformations associated with treatment with carbamazepine during pregnancy. ( Jones, RB; Sutcliffe, AG; Woodruff, G, 1998)
"The effects of antiepileptic drugs (AED) on infants during pregnancy and delivery were studied in a total of 82 epileptic mothers on various monotherapies; 29 cases receiving valproic acid (VPA), 20 receiving phenytoin (PHT), 18 on carbamazepine (CBZ) and 15 on phenobarbital (PB)."3.68[Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital]. ( Ishikawa, S; Izumi, M; Okada, H; Takeda, A; Tanaka, H, 1991)
"A girl was born to a mother who had undergone treatment for epilepsy with carbamazepine during pregnancy."3.68Teratogenic effect of carbamazepine. ( Vestermark, S; Vestermark, V, 1991)
"Neural tube, craniofacial, and other congenital abnormalities have been described in infants born to mothers with epilepsy who were treated with valproic acid (VPA) during pregnancy."3.67Congenital abnormalities in two sibs exposed to valproic acid in utero. ( Anderson, L; Chitayat, D; Farrell, K; Hall, JG, 1988)
"Evidence for the comparative teratogenic risk of antiepileptic drugs is insufficient, particularly in relation to the dosage used."1.48Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry. ( Battino, D; Bonizzoni, E; Craig, J; Lindhout, D; Perucca, E; Sabers, A; Thomas, SV; Tomson, T; Vajda, F, 2018)
"Carbamazepine and water were given by gastric gavage throughout gestational period."1.42Teratogenic effect of Carbamazepine use during pregnancy in the mice. ( El-Kenawy, Ael-M; Elshama, SS; Osman, HE, 2015)
" The mean dosage of AED for valproate was 498 mg/day and carbamazepine was 555 mg/day."1.39Malformation in index pregnancy in women with epilepsy is not followed by recurrence in subsequent pregnancy. ( Begum, S; Sarma, SP; Thomas, SV, 2013)
"Carbamazepine is an antiepileptic drug used widely for the treatment of epileptic seizures and neuropathic pain."1.36Teratogenic effects of carbamazepine on embryonic eye development in pregnant mice. ( Afshar, M; Houshang Mohammadpour, A; Jafar Golalipour, M; Majid Jalalian, S; Moallem, SA; Shiravi, A, 2010)
"Women with epilepsy have a higher risk of having dysmorphic child."1.33A case of fetal anticonvulsant syndrome with severe bilateral upper limb defect. ( Batukan, C; Ceylaner, G; Ceylaner, S; Guven, MA; Uzel, M, 2006)
" During this pregnancy the patient took a reduced dosage of carbamazepine."1.29Fetal malformations in an epileptic pregnant woman treated with carbamazepine. ( Caradonna, F; Caruso, G; Ceci, O; Clemente, R; Ferreri, R; Loizzi, P, 1996)
"Over the past 10 years, knowledge gained about the pharmacokinetic profiles of valproate and carbamazepine has increased the clinical effectiveness of their use."1.28Pharmacokinetics of valproate and carbamazepine. ( Wilder, BJ, 1992)
"Carbamazepine was the antiepileptic drug prescribed most frequently followed by valproic acid."1.28[The course of pregnancy and teratogenicity of antiepileptic agents in 66 patients with epilepsy]. ( Bülau, P; Fröscher, W; Herrmann, R; Hildenbrand, G; Niesen, M; Penin, H, 1991)
"Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment."1.27Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983)
"The objective of this investigation was to study the teratogenic effects of dosage levels and time of administration of three anticonvulsant drugs (carbamazepine [CMZ], sodium valproate [NaV], and diphenylhydantoin [DPH]) on craniofacial development in the CD-1 mouse fetus."1.27Teratogenic effects of dosage levels and time of administration of carbamazepine, sodium valproate, and diphenylhydantoin on craniofacial development in the CD-1 mouse fetus. ( Eluma, FO; Hayes, TG; Paulson, RB; Sucheston, ME, 1984)
"The incidence of malformations in fetal mice exposed to phenytoin depends on drug dosage and the strain of mice."1.26Teratogenic effects of anticonvulsants. ( Paulson, GW; Paulson, RB, 1981)

Research

Studies (123)

TimeframeStudies, this research(%)All Research%
pre-199038 (30.89)18.7374
1990's29 (23.58)18.2507
2000's31 (25.20)29.6817
2010's23 (18.70)24.3611
2020's2 (1.63)2.80

Authors

AuthorsStudies
Cohen, JM3
Alvestad, S3
Cesta, CE3
Bjørk, MH3
Leinonen, MK3
Nørgaard, M3
Einarsdóttir, K3
Engeland, A3
Gissler, M3
Karlstad, Ø3
Klungsøyr, K3
Odsbu, I3
Reutfors, J3
Selmer, RM3
Tomson, T7
Ulrichsen, SP3
Zoega, H3
Furu, K3
Vajda, F3
O'Brien, T1
Graham, J2
Hitchcock, A1
Perucca, P1
Lander, C1
Eadie, M1
Pariente, G1
Leibson, T1
Shulman, T1
Adams-Webber, T1
Barzilay, E1
Nulman, I2
Battino, D4
Bonizzoni, E2
Craig, J3
Lindhout, D6
Perucca, E4
Sabers, A2
Thomas, SV2
Giménez, A1
Pacchiarotti, I1
Gil, J1
Murru, A1
Gomes, SP1
Pinzón, JE1
Anmella, G1
Gómez-Ramiro, M1
Verdolini, N1
Valentí, M1
Goikolea, JM1
Vieta, E1
Tica, OS1
Tica, AA1
Brailoiu, CG1
Cernea, N1
Tica, VI1
Begum, S1
Sarma, SP1
Campbell, E1
Kennedy, F1
Russell, A1
Smithson, WH1
Parsons, L1
Morrison, PJ1
Liggan, B1
Irwin, B1
Delanty, N1
Hunt, SJ1
Morrow, J1
Elshama, SS1
Osman, HE1
El-Kenawy, Ael-M1
Vajda, FJE1
O'Brien, TJ2
Lander, CM1
Eadie, MJ2
Harden, CL1
Sethi, NK1
Aksamija, A1
Habek, D1
Stanojević, M1
Ujević, B1
Ackers, R1
Besag, FM1
Wade, A1
Murray, ML1
Wong, IC1
Bozhinov, P1
Bozhinova, C1
Markova, C1
Somerville, ER1
Cook, MJ1
Afshar, M1
Moallem, SA1
Houshang Mohammadpour, A1
Shiravi, A1
Majid Jalalian, S1
Jafar Golalipour, M1
Galbally, M1
Roberts, M1
Buist, A1
Jentink, J2
Dolk, H1
Loane, MA1
Morris, JK1
Wellesley, D1
Garne, E1
de Jong-van den Berg, L1
Chambers, CD2
Iniesta, I1
Holmes, LB4
Mittendorf, R1
Shen, A1
Smith, CR1
Hernandez-Diaz, S1
Kulaga, S1
Sheehy, O1
Zargarzadeh, AH1
Moussally, K1
Bérard, A1
Werler, MM1
Ahrens, KA1
Bosco, JL1
Mitchell, AA1
Anderka, MT1
Gilboa, SM1
Matlow, J1
Koren, G2
Boersma, C1
de Jong-van den Berg, LT1
Postma, MJ1
Akar, M1
Dilli, D1
Yilmaz, Y1
Erdeve, O1
Oguz, S1
Uras, N1
Dilmen, U1
Dursun, A1
Karadağ, N1
Karagöl, B1
Kundak, AA1
Zenciroğlu, A1
Okumuş, N1
Ceylaner, S2
Bravo, A1
Hernandez, D1
Martinez-Villarreal, L1
Elizondo, G1
Esmer, C1
Kaaja, E1
Kaaja, R1
Hiilesmaa, V1
Miller, M1
D'Souza, J1
Zaninelli, R1
Meischenguiser, R2
D'Giano, CH2
Ferraro, SM2
Shorvon, SD1
Karlov, VA1
Coull, BA2
Dorfman, J1
Rosenberger, PB1
Montouris, G1
Kini, U1
Adab, N1
Vinten, J1
Fryer, A1
Clayton-Smith, J1
Guven, MA1
Batukan, C1
Ceylaner, G1
Uzel, M1
Barqawi, R1
Meador, KJ1
Baker, GA1
Finnell, RH1
Kalayjian, LA1
Liporace, JD1
Loring, DW1
Mawer, G1
Pennell, PB1
Smith, JC1
Wolff, MC1
Puhó, EH1
Szunyogh, M1
Métneki, J1
Czeizel, AE1
Manent, JB1
Jorquera, I1
Mazzucchelli, I1
Depaulis, A1
Ben-Ari, Y1
Represa, A1
James, L1
Barnes, TR1
Lelliott, P1
Taylor, D1
Paton, C1
Friis, ML1
Keränen, T1
Sivenius, J1
Loiseau, P2
Eluma, FO1
Sucheston, ME1
Hayes, TG1
Paulson, RB2
Sereno Colo, JA1
Domínguez Chavez, FJ1
Núñez Gutiérrez, J1
Butler, CD1
El-Sayed, MG1
Aly, AE1
Kadri, M1
Moustafa, AM1
Kuhnz, W1
Jäger-Roman, E1
Rating, D1
Deichl, A1
Kunze, J1
Helge, H1
Nau, H2
Höppener, RJ1
Meinardi, H2
Paulson, GW1
Philbert, A1
Dam, M1
Pedersen, A1
Poskitt, EM1
Hensey, OJ1
Smith, CS1
Zenk, KE1
Wray, SD1
Hassell, TM1
Phillips, C1
Johnston, MC1
Oakeshott, P2
Hunt, G1
Ylagan, LR1
Budorick, NE1
Martin, PJ1
Millac, PA1
Kaneko, S1
Otani, K1
Kondo, T1
Fukushima, Y1
Kan, R1
Takeda, A2
Nakane, Y1
Little, BB1
Santos-Ramos, R1
Newell, JF1
Maberry, MC1
Omtzigt, JG1
Los, FJ1
Meijer, JW2
Ceci, O1
Loizzi, P1
Caruso, G1
Caradonna, F1
Clemente, R1
Ferreri, R1
Quattrini, A1
Ortenzi, A1
Paggi, A1
Foschi, N1
Quattrini, C1
Yerby, MS3
Azarbayjani, F1
Danielsson, BR1
Baptista, T1
Araujo, H1
Rada, P1
Hernández, L1
Tueth, MJ1
Murphy, TK1
Evans, DL1
Sutcliffe, AG1
Jones, RB1
Woodruff, G1
Canger, R1
Canevini, MP1
Fumarola, C1
Guidolin, L1
Vignoli, A1
Mamoli, D1
Palmieri, C1
Molteni, F1
Granata, T1
Hassibi, P1
Zamperini, P1
Pardi, G1
Avanzini, G1
Moore, SJ2
Turnpenny, P1
Quinn, A1
Glover, S1
Lloyd, DJ1
Montgomery, T1
Dean, JC2
Fairgrieve, SD1
Jackson, M1
Jonas, P1
Walshaw, D1
White, K1
Montgomery, TL1
Burn, J1
Lynch, SA1
Iqbal, MM1
Gundlapalli, SP1
Ryan, WG1
Ryals, T1
Passman, TE1
Harvey, EA1
Huntington, KB1
Khoshbin, S1
Hayes, AM1
Ryan, LM1
Johnson, KA2
Weber, PA1
Jones, KL2
Diav-Citrin, O1
Shechtman, S1
Arnon, J1
Ornoy, A1
Glover, SJ1
Quinn, AG1
Barter, P1
Hart, J1
Turnpenny, PD1
Livingston, S1
Pruce, I1
Pauli, LL1
Janz, D1
Conomy, JP1
Swanson, PD1
Hicks, EP1
Sullivan, FM1
McElhatton, PR1
Wilder, BJ1
Leavitt, A1
Erickson, DM1
McCormick, KB1
Loewenson, RB1
Sells, CJ1
Benedetti, TJ1
Gladstone, DJ1
Bologa, M1
Maguire, C1
Pastuszak, A1
Fröscher, W2
Herrmann, R1
Niesen, M2
Bülau, P1
Penin, H1
Hildenbrand, G1
Tanaka, H1
Izumi, M1
Okada, H1
Ishikawa, S1
Hunt, GM1
van der Pol, MC1
Hadders-Algra, M1
Huisjes, HJ1
Touwen, BC1
Rosa, FW1
Legido, A2
Toomey, K2
Goldsmith, L2
Vestermark, V1
Vestermark, S1
Cohen, LS1
Heller, VL1
West, J1
Burke, JP1
Strachan, I1
Chadwick, D1
Piccione, E1
Ticconi, C1
Cennamo, M1
Pellock, JM1
Lacro, RV1
Adams, J1
Bag, S1
Behari, M1
Ahuja, GK1
Karmarkar, MG1
Pacifici, GM1
Bertilsson, L1
Rane, A1
Bertollini, R1
Källen, B1
Mastroiacovo, P1
Robert, E1
Wladimiroff, JW1
Stewart, PA1
Reuss, A1
van Swaay, E1
Sachs, ES1
Chitayat, D1
Farrell, K1
Anderson, L1
Hall, JG1
Calabrese, JR1
Gulledge, AD1
Dalessio, DJ1
Meyer, JG1
Henry, TP1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822]550 participants (Anticipated)Observational2022-02-18Recruiting
Neurodevelopmental Effects of Antiepileptic Drugs II: the NEAD Study[NCT00021866]331 participants (Actual)Observational2000-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

20 reviews available for carbamazepine and Abnormalities, Drug-Induced

ArticleYear
Pregnancy Outcomes Following In Utero Exposure to Lamotrigine: A Systematic Review and Meta-Analysis.
    CNS drugs, 2017, Volume: 31, Issue:6

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newbo

2017
Adverse outcomes during pregnancy and major congenital malformations in infants of patients with bipolar and schizoaffective disorders treated with antiepileptic drugs: A systematic review.
    Psychiatria polska, 2019, Apr-30, Volume: 53, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Bipolar Disorder; Carbamazepine; Female; Humans

2019
Is carbamazepine a human teratogen?
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 23

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Australia; Carbamazepine; Epilepsy; Female; Fet

2016
Epileptic disorders in pregnancy: an overview.
    Current opinion in obstetrics & gynecology, 2008, Volume: 20, Issue:6

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Folic Acid; Hemorrhag

2008
Fetal malformations associated with the use of methylphenobarbital and carbamazepine during pregnancy. Two case reports and review of the literature.
    Fetal diagnosis and therapy, 2009, Volume: 25, Issue:1

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male;

2009
Mood stabilizers in pregnancy: a systematic review.
    The Australian and New Zealand journal of psychiatry, 2010, Volume: 44, Issue:11

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Carbamazepin

2010
Intrauterine exposure to carbamazepine and specific congenital malformations: systematic review and case-control study.
    BMJ (Clinical research ed.), 2010, Dec-02, Volume: 341

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Case-Control Studies; Epilepsy; Europe;

2010
[Therapy of epilepsy: current strategy and tactics].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2004, Volume: 104, Issue:8

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Child;

2004
Safety of the newer antiepileptic drug oxcarbazepine during pregnancy.
    Current medical research and opinion, 2005, Volume: 21, Issue:5

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Carbamazepine; Female; Humans; Oxcarba

2005
Antiepileptic drugs as human teratogens.
    Expert opinion on drug safety, 2008, Volume: 7, Issue:2

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital

2008
The epileptic mother and her child.
    Epilepsia, 1982, Volume: 23, Issue:1

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Fetal

1982
An overview of perinatal clinical pharmacology.
    Clinics in laboratory medicine, 1981, Volume: 1, Issue:2

    Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digo

1981
Special considerations: use of lithium in children, adolescents, and elderly populations.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 6

    Topics: Abnormalities, Drug-Induced; Acetates; Adolescent; Adult; Age Factors; Aged; Amines; Anticonvulsants

1998
Effects of antimanic mood-stabilizing drugs on fetuses, neonates, and nursing infants.
    Southern medical journal, 2001, Volume: 94, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Antimanic Agents; Benzodiazepines; Breast Feed

2001
The teratogenic risk of antiepileptic drugs.
    Epilepsia, 1975, Volume: 16, Issue:1

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anencephaly; Anti-Anxiety Agents; Anticonvulsa

1975
Spina bifida in infants of women treated with carbamazepine during pregnancy.
    The New England journal of medicine, 1991, Mar-07, Volume: 324, Issue:10

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Epilepsy; Female; Human

1991
[Problems of neurological drug therapy in pregnancy].
    La Clinica terapeutica, 1989, Apr-30, Volume: 129, Issue:2

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Antiparkinson Agents; Carbamazepine; Chelating Agents;

1989
Efficacy and adverse effects of antiepileptic drugs.
    Pediatric clinics of North America, 1989, Volume: 36, Issue:2

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital

1989
Problems and management of the pregnant woman with epilepsy.
    Epilepsia, 1987, Volume: 28 Suppl 3

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Pregnancy; Pr

1987
Current concepts. Seizure disorders and pregnancy.
    The New England journal of medicine, 1985, Feb-28, Volume: 312, Issue:9

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Administration Schedule; Epilepsy;

1985

Trials

3 trials available for carbamazepine and Abnormalities, Drug-Induced

ArticleYear
Major malformations in offspring of women with epilepsy.
    Neurology, 2003, Dec-09, Volume: 61, Issue:11

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Logistic Mode

2003
Evaluation of antiepileptic drugs in pregnancy in a Jordanian army hospital.
    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 2005, Volume: 11, Issue:4

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Clinical Protocols; Drug Monitor

2005
In utero antiepileptic drug exposure: fetal death and malformations.
    Neurology, 2006, Aug-08, Volume: 67, Issue:3

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Cognition; Female; Fetal Death;

2006

Other Studies

100 other studies available for carbamazepine and Abnormalities, Drug-Induced

ArticleYear
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
    Annals of neurology, 2023, Volume: 93, Issue:3

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep

2023
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
    Annals of neurology, 2023, Volume: 93, Issue:3

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep

2023
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
    Annals of neurology, 2023, Volume: 93, Issue:3

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep

2023
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
    Annals of neurology, 2023, Volume: 93, Issue:3

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep

2023
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
    Annals of neurology, 2023, Volume: 93, Issue:3

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep

2023
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
    Annals of neurology, 2023, Volume: 93, Issue:3

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep

2023
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
    Annals of neurology, 2023, Volume: 93, Issue:3

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep

2023
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
    Annals of neurology, 2023, Volume: 93, Issue:3

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep

2023
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
    Annals of neurology, 2023, Volume: 93, Issue:3

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilep

2023
Specific fetal malformations following intrauterine exposure to antiseizure medication.
    Epilepsy & behavior : E&B, 2023, Volume: 142

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Australia; Carbamazepine; Female; Humans; Male; Pregna

2023
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.
    The Lancet. Neurology, 2018, Volume: 17, Issue:6

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug

2018
Sirenomelia after phenobarbital and carbamazepine therapy in pregnancy.
    Birth defects research. Part A, Clinical and molecular teratology, 2013, Volume: 97, Issue:6

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Ectromelia; Epilepsy; Fatal Outcome; Female; Humans; Phe

2013
Malformation in index pregnancy in women with epilepsy is not followed by recurrence in subsequent pregnancy.
    Epilepsia, 2013, Volume: 54, Issue:12

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; India; Pregna

2013
Malformation risks of antiepileptic drug monotherapies in pregnancy: updated results from the UK and Ireland Epilepsy and Pregnancy Registers.
    Journal of neurology, neurosurgery, and psychiatry, 2014, Volume: 85, Issue:9

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug

2014
Teratogenic effect of Carbamazepine use during pregnancy in the mice.
    Pakistan journal of pharmaceutical sciences, 2015, Volume: 28, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Female; Fetal Growth Retardati

2015
Changing trends in antiepileptic drug prescribing in girls of child-bearing potential.
    Archives of disease in childhood, 2009, Volume: 94, Issue:6

    Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Child; Contraceptive Agents

2009
[Fetal malformations in women with epilepsy].
    Akusherstvo i ginekologiia, 2009, Volume: 48, Issue:1

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Bulgaria; Carbamazepine; Epilepsy; Female; Humans; Inf

2009
Pregnancy treatment guidelines: throwing the baby out with the bath water.
    Epilepsia, 2009, Volume: 50, Issue:9

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Femal

2009
Teratogenic effects of carbamazepine on embryonic eye development in pregnant mice.
    Cutaneous and ocular toxicology, 2010, Volume: 29, Issue:1

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Analgesics, Non-Narcotic; Animals; Anticonvuls

2010
Valproic acid: long-term effects on children exposed in utero.
    Prescrire international, 2009, Volume: 18, Issue:104

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Contraindications; Dose

2009
Carbamazepine in pregnancy.
    BMJ (Clinical research ed.), 2010, Dec-02, Volume: 341

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newbo

2010
Value of the small cohort study including a physical examination for minor structural defects in identifying new human teratogens.
    Congenital anomalies, 2011, Volume: 51, Issue:1

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Antidepressive Agents; Arthritis, Rheumatoid; Carbamaz

2011
Carbamazepine in pregnancy: Levetiracetam and lamotrigine are better options.
    BMJ (Clinical research ed.), 2011, Jan-25, Volume: 342

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Contraindications; Epilepsy; Female; Hu

2011
Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry.
    The Lancet. Neurology, 2011, Volume: 10, Issue:7

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epile

2011
Fetal effects of anticonvulsant polytherapies: different risks from different drug combinations.
    Archives of neurology, 2011, Volume: 68, Issue:10

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Canada; Carbamazepine; Cohort Studies; Drug Therapy, C

2011
Antiepileptic drug use during pregnancy: perinatal outcomes.
    Seizure, 2011, Volume: 20, Issue:9

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Cohort Studies; Drug

2011
Use of antiepileptic medications in pregnancy in relation to risks of birth defects.
    Annals of epidemiology, 2011, Volume: 21, Issue:11

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Hu

2011
Is carbamazepine safe to take during pregnancy?
    Canadian family physician Medecin de famille canadien, 2012, Volume: 58, Issue:2

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Neural Tube D

2012
Economic evaluation of anti-epileptic drug therapies with specific focus on teratogenic outcomes.
    Journal of medical economics, 2012, Volume: 15, Issue:5

    Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Cost-Benefit Analysis; Epil

2012
A case of fetal carbamazepine syndrome with right hemihypoplasia of the entire body.
    Genetic counseling (Geneva, Switzerland), 2012, Volume: 23, Issue:1

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Bone and Bones; Carbamazepine; Congenital Abnormalitie

2012
Carbamazepine use in pregnancy and coincidental thalidomide-like phocomelia in a newborn.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2012, Volume: 32, Issue:5

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Ectromelia; Female; Humans; Infant, New

2012
Severe consequences of carbamazepine exposure in utero.
    BMJ case reports, 2011, Aug-04, Volume: 2011

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant

2011
Major malformations in offspring of women with epilepsy.
    Neurology, 2003, Feb-25, Volume: 60, Issue:4

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Comorbidity; Educational Status;

2003
Major malformations in offspring of women with epilepsy.
    Neurology, 2003, Dec-09, Volume: 61, Issue:11

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Logistic Mode

2003
Oxcarbazepine in pregnancy: clinical experience in Argentina.
    Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:2

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Argentina; Carbamazepine; Drug Therapy, Combination; E

2004
Navigating toward fetal and maternal health: the challenge of treating epilepsy in pregnancy.
    Epilepsia, 2004, Volume: 45, Issue:10

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Child; Cohort Studies; Confoundi

2004
Longer term outcome of children born to mothers with epilepsy.
    Journal of neurology, neurosurgery, and psychiatry, 2004, Volume: 75, Issue:11

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Fema

2004
The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs.
    The Journal of pediatrics, 2005, Volume: 146, Issue:1

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cognition Disorders; Face; Facie

2005
Dysmorphic features: an important clue to the diagnosis and severity of fetal anticonvulsant syndromes.
    Archives of disease in childhood. Fetal and neonatal edition, 2006, Volume: 91, Issue:2

    Topics: Abnormalities, Drug-Induced; Adolescent; Anthropometry; Anticonvulsants; Carbamazepine; Child; Child

2006
A case of fetal anticonvulsant syndrome with severe bilateral upper limb defect.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2006, Volume: 19, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fetal Diseases

2006
Drug treatment during pregnancy and isolated orofacial clefts in hungary.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2007, Volume: 44, Issue:2

    Topics: Abnormalities, Drug-Induced; Adrenergic beta-Antagonists; Amoxicillin; Anti-Bacterial Agents; Antico

2007
Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias.
    Epilepsia, 2007, Volume: 48, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Female; Fetus

2007
Informing patients of the teratogenic potential of mood stabilizing drugs: a case note review of the practice of psychiatrists.
    Journal of psychopharmacology (Oxford, England), 2007, Volume: 21, Issue:8

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Affect; Antimanic Agents; Carbamazepine; Counseling;

2007
Antiepileptic drugs and teratogenesis. How should patients, doctors and health authorities be counselled?
    Acta neurologica Scandinavica. Supplementum, 1983, Volume: 94

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newbo

1983
Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy.
    Acta neurologica Scandinavica. Supplementum, 1983, Volume: 97

    Topics: Abnormalities, Drug-Induced; Arousal; Benzodiazepinones; Carbamazepine; Chemical and Drug Induced Li

1983
Rational use of valproate: indications and drug regimen in epilepsy.
    Epilepsia, 1984, Volume: 25 Suppl 1

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child,

1984
Teratogenic effects of dosage levels and time of administration of carbamazepine, sodium valproate, and diphenylhydantoin on craniofacial development in the CD-1 mouse fetus.
    Journal of craniofacial genetics and developmental biology, 1984, Volume: 4, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Dr

1984
[Treatment of pregnant epileptics with carbamazepine. Preliminary report].
    Ginecologia y obstetricia de Mexico, 1984, Volume: 52, Issue:329

    Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Epilepsy; Female; Humans; Pregnancy; Pregnancy Co

1984
Carbamazepine, seizure disorders, and pregnancy.
    JAMA, 1983, Dec-16, Volume: 250, Issue:23

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Epilepsy; Female; Humans; Pregnancy; Pregnancy Complicat

1983
Comparative study on the teratogenicity of some antiepileptics in the rat.
    East African medical journal, 1983, Volume: 60, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Carbamazepine; Ethos

1983
Carbamazepine and carbamazepine-10,11- epoxide during pregnancy and postnatal period in epileptic mother and their nursed infants: pharmacokinetics and clinical effects.
    Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:3-4

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Female;

1983
Teratogenicity of antiepileptic drug combinations with special emphasis on epoxidation (of carbamazepine).
    Epilepsia, 1984, Volume: 25, Issue:1

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Therapy,

1984
Teratogenic effects of anticonvulsants.
    Archives of neurology, 1981, Volume: 38, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Cleft Palate; Eyelid Diseases;

1981
[Valproate and congenital abnormalities].
    Ugeskrift for laeger, 1982, Dec-06, Volume: 144, Issue:49

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Female; Humans; Pregnancy; Valproic Acid

1982
Alcohol, other drugs and the fetus.
    Developmental medicine and child neurology, 1982, Volume: 24, Issue:5

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Dextropropoxyphene; Diazepam; Drug Synergism; Female; Fe

1982
Preliminary study of the effects of carbamazepine on congenital orofacial defects in offspring of A/J mice.
    Epilepsia, 1982, Volume: 23, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Carbamazepine; Cleft Lip; Cleft Palate; Female; Maternal-Fetal

1982
Prevention of neural tube defects.
    Lancet (London, England), 1994, Jan-08, Volume: 343, Issue:8889

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Female; Folic Acid; Humans; Neural Tube Defects; Pregnan

1994
Radial ray aplasia in utero: a prenatal finding associated with valproic acid exposure.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 1994, Volume: 13, Issue:5

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Carbamazepine; Epilepsy, Absence; Female; Huma

1994
Pregnancy, epilepsy, management and outcome: a 10-year perspective.
    Seizure, 1993, Volume: 2, Issue:4

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Birth Weight; Carbamazepine; Cohort Studies; Drug Ther

1993
Teratogenicity of antiepileptic drugs and drug specific malformations.
    The Japanese journal of psychiatry and neurology, 1993, Volume: 47, Issue:2

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug

1993
Megadose carbamazepine during the period of neural tube closure.
    Obstetrics and gynecology, 1993, Volume: 82, Issue:4 Pt 2 Sup

    Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Central Nervous System; Female; Humans; Neural Tu

1993
The 10,11-epoxide-10,11-diol pathway of carbamazepine in early pregnancy in maternal serum, urine, and amniotic fluid: effect of dose, comedication, and relation to outcome of pregnancy.
    Therapeutic drug monitoring, 1993, Volume: 15, Issue:1

    Topics: Abnormalities, Drug-Induced; Amniotic Fluid; Carbamazepine; Cohort Studies; Dose-Response Relationsh

1993
Fetal malformations in an epileptic pregnant woman treated with carbamazepine.
    Zentralblatt fur Gynakologie, 1996, Volume: 118, Issue:3

    Topics: Abnormalities, Drug-Induced; Abortion, Eugenic; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Fem

1996
Lamotrigine and pregnancy.
    Italian journal of neurological sciences, 1996, Volume: 17, Issue:6

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Femal

1996
Teratogenic effects of antiepileptic drugs: what do we advise patients?
    Epilepsia, 1997, Volume: 38, Issue:9

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Patient Advoc

1997
Pharmacologically induced embryonic dysrhythmia and episodes of hypoxia followed by reoxygenation: a common teratogenic mechanism for antiepileptic drugs?
    Teratology, 1998, Volume: 57, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac;

1998
Congenital neuroblastoma in a boy born to a woman with bipolar disorder treated with carbamazepine during pregnancy.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:3

    Topics: Abnormalities, Drug-Induced; Adrenal Gland Neoplasms; Adult; Anticonvulsants; Bipolar Disorder; Carb

1998
Eye malformations associated with treatment with carbamazepine during pregnancy.
    Ophthalmic genetics, 1998, Volume: 19, Issue:2

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Coloboma; Eye Abnormalities; Female; Fe

1998
Malformations in offspring of women with epilepsy: a prospective study.
    Epilepsia, 1999, Volume: 40, Issue:9

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Comorbidity; Congenital Abnormalities;

1999
A clinical study of 57 children with fetal anticonvulsant syndromes.
    Journal of medical genetics, 2000, Volume: 37, Issue:7

    Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Ep

2000
Population based, prospective study of the care of women with epilepsy in pregnancy.
    BMJ (Clinical research ed.), 2000, Sep-16, Volume: 321, Issue:7262

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fetal Death; Guidelin

2000
Valproate and other anticonvulsants for psychiatric disorders.
    The Medical letter on drugs and therapeutics, 2000, Dec-11, Volume: 42, Issue:1094

    Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Bipolar

2000
The teratogenicity of anticonvulsant drugs.
    The New England journal of medicine, 2001, Apr-12, Volume: 344, Issue:15

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Case-Control Studies; Congenital Abnorm

2001
Selection bias in Teratology Information Service pregnancy outcome studies.
    Teratology, 2001, Volume: 64, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; California; Carbamazepine; Drug Information Ser

2001
Is carbamazepine teratogenic? A prospective controlled study of 210 pregnancies.
    Neurology, 2001, Jul-24, Volume: 57, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Pregna

2001
Ophthalmic findings in fetal anticonvulsant syndrome(s).
    Ophthalmology, 2002, Volume: 109, Issue:5

    Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Ep

2002
The medical treatment of epilepsy: antiepileptic drug interactions and teratogenicity.
    Pediatric annals, 1979, Volume: 8, Issue:4

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Calcium; Carbamazepine; Child; Dicumarol; Digit

1979
Long-term use of the major anticonvulsant drugs.
    American family physician, 1978, Volume: 18, Issue:4

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximi

1978
Anticonvulsant therapy. Approaches to some common clinical problems.
    Postgraduate medicine, 1979, Volume: 65, Issue:3

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Eth

1979
Carbamazepine in two pregnancies.
    Clinical and experimental neurology, 1979, Volume: 16

    Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Epilepsy; Female; Fetal Death; Humans; Maternal-F

1979
A comparison of the teratogenic activity of the antiepileptic drugs carbamazepine, clonazepam, ethosuximide, phenobarbital, phenytoin, and primidone in mice.
    Toxicology and applied pharmacology, 1977, Volume: 40, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Fema

1977
Pharmacokinetics of valproate and carbamazepine.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:1 Suppl

    Topics: Abnormalities, Drug-Induced; Animals; Carbamazepine; Humans; Intestinal Absorption; Protein Binding;

1992
Antiepileptics and the development of congenital anomalies.
    Neurology, 1992, Volume: 42, Issue:4 Suppl 5

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Apgar Score; Birth Weight; Carbamazepine; Epilepsy; Fe

1992
Antiepileptic drugs and teratogenesis in two consecutive cohorts: changes in prescription policy paralleled by changes in pattern of malformations.
    Neurology, 1992, Volume: 42, Issue:4 Suppl 5

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Drug Prescriptions; Epi

1992
Course of pregnancy and fetal outcome following maternal exposure to carbamazepine and phenytoin: a prospective study.
    Reproductive toxicology (Elmsford, N.Y.), 1992, Volume: 6, Issue:3

    Topics: Abnormalities, Drug-Induced; Analysis of Variance; Carbamazepine; Epilepsy; Female; Humans; Phenytoi

1992
Teratogenesis with carbamazepine.
    Lancet (London, England), 1991, Jun-01, Volume: 337, Issue:8753

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Epilepsy; Female; Humans; Pregnancy; Pregnancy Complicat

1991
[The course of pregnancy and teratogenicity of antiepileptic agents in 66 patients with epilepsy].
    Schweizer Archiv fur Neurologie und Psychiatrie (Zurich, Switzerland : 1985), 1991, Volume: 142, Issue:5

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combin

1991
[Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital].
    Rinsho shinkeigaku = Clinical neurology, 1991, Volume: 31, Issue:3

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Birth Weight; Carbamazepine; Embryonic and Feta

1991
Carbamazepine and spina bifida.
    BMJ (Clinical research ed.), 1991, Sep-14, Volume: 303, Issue:6803

    Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Female; Humans; Infant, Newborn; Pregnancy; Spina

1991
Antiepileptic medication in pregnancy: late effects on the children's central nervous system development.
    American journal of obstetrics and gynecology, 1991, Volume: 164, Issue:1 Pt 1

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Central Nervous System; Child; Child De

1991
Congenital rib anomalies in a fetus exposed to carbamazepine.
    Clinical pediatrics, 1991, Volume: 30, Issue:1

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Female; Fetus; Humans; Infant, Newborn; Maternal-Fetal E

1991
Congenital rib anomalies in a fetus exposed to carbamazepine.
    Clinical pediatrics, 1991, Volume: 30, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Female; Fetus; Humans; Infant, Newborn; Ribs

1991
Teratogenic effect of carbamazepine.
    Archives of disease in childhood, 1991, Volume: 66, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Epilepsy; Facial Bones; Female; Humans; Infant, N

1991
On the use of anticonvulsants for manic depression during pregnancy.
    Psychosomatics, 1990,Fall, Volume: 31, Issue:4

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Bipolar Disorder; Carbamazepine; Female; Humans; Infan

1990
Carbamazepine, epilepsy, and optic nerve hypoplasia.
    The British journal of ophthalmology, 1990, Volume: 74, Issue:8

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Epilepsy; Female; Humans; Infant, Newborn; Optic Nerve

1990
Epilepsy in women of childbearing age.
    BMJ (Clinical research ed.), 1989, Oct-14, Volume: 299, Issue:6705

    Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Child; Epilepsy; Female; Humans; Pregnancy; Pregn

1989
Epilepsy in women of childbearing age.
    BMJ (Clinical research ed.), 1989, Nov-04, Volume: 299, Issue:6708

    Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Epilepsy; Female; Humans; Pregnancy; Pregnancy Co

1989
Pattern of malformations in the children of women treated with carbamazepine during pregnancy.
    The New England journal of medicine, 1989, Jun-22, Volume: 320, Issue:25

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Female; Fetu

1989
Pregnancy and epilepsy.
    Journal of neurology, 1989, Volume: 236, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Estrogens; Female; Hum

1989
Teratogenic effects of carbamazepine.
    The New England journal of medicine, 1989, Nov-23, Volume: 321, Issue:21

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Epilepsy; Female; Fetus; Humans; Pregnancy; Pregnancy Co

1989
Valpromide/carbamazepine and risk of teratogenicity.
    Lancet (London, England), 1985, Feb-16, Volume: 1, Issue:8425

    Topics: Abnormalities, Drug-Induced; Animals; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Hu

1985
Anticonvulsant drugs in monotherapy. Effect on the fetus.
    European journal of epidemiology, 1987, Volume: 3, Issue:2

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fe

1987
The role of ultrasound in the early diagnosis of fetal structural defects following maternal anticonvulsant therapy.
    Ultrasound in medicine & biology, 1988, Volume: 14, Issue:8

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Diazepam; Female; Humans; Infant, Newbo

1988
Congenital abnormalities in two sibs exposed to valproic acid in utero.
    American journal of medical genetics, 1988, Volume: 31, Issue:2

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Infan

1988
Carbamazepine, clonazepam use during pregnancy.
    Psychosomatics, 1986, Volume: 27, Issue:6

    Topics: Abnormalities, Drug-Induced; Benzodiazepinones; Carbamazepine; Clonazepam; Epilepsy; Female; Humans;

1986
Finger- and toenail hypoplasia after carbamazepine monotherapy in late pregnancy.
    Neuropediatrics, 1985, Volume: 16, Issue:3

    Topics: Abnormalities, Drug-Induced; Adult; Carbamazepine; Epilepsy; Female; Humans; Infant, Newborn; Nails,

1985
The teratological effects of anticonvulsants and the effects on pregnancy and birth.
    European neurology, 1973, Volume: 10, Issue:3

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cleft Lip; Cleft Palate; Cyclohe

1973
[Letter: Teratogenic hazards in antiepileptic therapy].
    La Nouvelle presse medicale, 1974, Jan-12, Volume: 3, Issue:2

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Preg

1974