carbamazepine has been researched along with Abnormalities, Autosome in 8 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Following treatment with antiepileptic drugs (AEDs), the patient developed several rare complications: after beginning therapy with phenytoin, the patient developed pseudolymphoma; after monotherapy with carbamazepine (CBZ), the patient thereafter developed myoclonic jerks of upper and lower limbs upon awakening; after one year of treatment with valproate (VPA) the patient developed clinical and immuno-haematological signs of SLE." | 3.69 | Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p. ( Diomedi, M; Gigli, GL; Masala, C; Placidi, F; Pomponi, MG; Scalise, A; Silvestri, G, 1996) |
| "A 25-year-old Oriental woman developed systemic lupus erythematosus during a course of treatment with carbamazepine for long-standing idiopathic epilepsy." | 3.65 | IgA deficiency and systemic lupus erythematosus. Occurrence in an oriental woman with idiopathic epilepsy. ( Imamura, S; Kanoh, T; Takahashi, C; Takigawa, M, 1976) |
| "Sister chromatid exchanges (SCEs) and chromosomal aberrations (CAs) genotoxic assays were utilized to achieve the study objective." | 1.91 | Reduction of Genotoxicity of Carbamazepine to Human Lymphocytes by Pre-treatment with Vitamin B12. ( Al-Eitan, LN; Alzoubi, KH; Hendawi, EK; Khabour, OF, 2023) |
| "Analysis of chromosome aberrations (CA), sister chromatid exchanges (SCEs), mitotic and proliferation indices (PRI) were performed." | 1.30 | In vivo and in vitro evaluation of the mutagenic potential of carbamazepine: does melatonin have anti-mutagenic activity? ( Awara, WM; El-Gohary, M; El-Nabi, SH; Fadel, WA, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Hendawi, EK | 1 |
| Khabour, OF | 1 |
| Al-Eitan, LN | 1 |
| Alzoubi, KH | 1 |
| Atlı Şekeroğlu, Z | 1 |
| Kefelioğlu, H | 1 |
| Kontaş Yedier, S | 1 |
| Şekeroğlu, V | 1 |
| Delmecioğlu, B | 1 |
| Königstein, M | 1 |
| Larisch, M | 1 |
| Obe, G | 2 |
| Sinués, B | 1 |
| Gazulla, J | 1 |
| Bernal, ML | 1 |
| Lanuza, J | 1 |
| Fanlo, A | 1 |
| Saenz, MA | 1 |
| Barolome, M | 1 |
| Gigli, GL | 1 |
| Scalise, A | 1 |
| Silvestri, G | 1 |
| Diomedi, M | 1 |
| Placidi, F | 1 |
| Pomponi, MG | 1 |
| Masala, C | 1 |
| Awara, WM | 1 |
| El-Gohary, M | 1 |
| El-Nabi, SH | 1 |
| Fadel, WA | 1 |
| Takigawa, M | 1 |
| Kanoh, T | 1 |
| Imamura, S | 1 |
| Takahashi, C | 1 |
| Herha, J | 1 |
8 other studies available for carbamazepine and Abnormalities, Autosome
| Article | Year |
|---|---|
Reduction of Genotoxicity of Carbamazepine to Human Lymphocytes by Pre-treatment with Vitamin B12.
Topics: Benzodiazepines; Carbamazepine; Chromosome Aberrations; DNA Damage; Humans; Lymphocytes; Vitamin B 1 | 2023 |
Oxcarbazepine-induced cytotoxicity and genotoxicity in human lymphocyte cultures with or without metabolic activation.
Topics: Adult; Anticonvulsants; Carbamazepine; Cell Survival; Cells, Cultured; Chromosome Aberrations; Dose- | 2017 |
Mutagenicity of antiepileptic drugs. I. Carbamazepine and some of its metabolites.
Topics: Carbamazepine; Cells, Cultured; Chromosome Aberrations; Crossing Over, Genetic; Humans; Lymphocytes; | 1984 |
Six mutagenicity assays in exposure biomonitoring of patients receiving carbamazepine for epilepsy or trigeminal neuralgia.
Topics: Adolescent; Adult; Aged; Biotransformation; Carbamazepine; Case-Control Studies; Cell Division; Chil | 1995 |
Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Chromosome Aberrations; Chromosome Disorders; Chromoso | 1996 |
In vivo and in vitro evaluation of the mutagenic potential of carbamazepine: does melatonin have anti-mutagenic activity?
Topics: Adult; Anticonvulsants; Carbamazepine; Chromosome Aberrations; Female; Humans; Lymphocytes; Male; Me | 1998 |
IgA deficiency and systemic lupus erythematosus. Occurrence in an oriental woman with idiopathic epilepsy.
Topics: Adult; B-Lymphocytes; Carbamazepine; Chromosome Aberrations; Chromosome Disorders; Dysgammaglobuline | 1976 |
Chromosomal damage in epileptics on monotherapy with carbamazepine and diphenylhydantoin.
Topics: Adolescent; Adult; Carbamazepine; Chromosome Aberrations; Chromosomes; Epilepsy; Female; Humans; Mal | 1976 |