carbamates has been researched along with Weight Gain in 18 studies
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Over 13 weeks, both repaglinide and gliclazide, when combined with bedtime NPH insulin produce similar significant improvements in glycaemic control (-1%) and similar weight gain." | 5.10 | Comparison of repaglinide vs. gliclazide in combination with bedtime NPH insulin in patients with Type 2 diabetes inadequately controlled with oral hypoglycaemic agents. ( Furlong, NJ; Hardy, KJ; Hulme, SA; O'Brien, SV, 2003) |
| " One such combination regimen is repaglinide (a prandial glucose regulator that increases insulin release) plus metformin (an insulin sensitizer that inhibits hepatic glucose output, increases peripheral glucose uptake and utilization and minimizes weight gain)." | 4.84 | Oral combination therapy: repaglinide plus metformin for treatment of type 2 diabetes. ( Raskin, P, 2008) |
| " The sulfonyluereas, repaglinide, metformin, acarbose and the thiazolidinediones are effective in decreasing fasting plasma glucose levels, but their limitations may include adverse effects, such as weight gain and hypoglycemia, and an inability to modify some of the important comorbidities of diabetes." | 4.80 | Advances in oral therapy for type 2 diabetes. ( Davis, SN, 2000) |
| "A population pharmacokinetic (PK) model, including seven clinical studies, was developed to explore the effect of covariates on givinostat PK." | 3.30 | Population pharmacokinetic-pharmacodynamic analysis of givinostat. ( Bettica, P; Cazzaniga, S; Del Bene, F; Fiorentini, F; Germani, M; Pellizzoni, C; Rocchetti, M, 2023) |
| " In this study, the effects of insulin glargine (IG) in combination with repaglinide or acarbose on glycemic parameters were investigated." | 2.74 | The investigation of the efficacy of insulin glargine on glycemic control when combined with either repaglinide or acarbose in obese Type 2 diabetic patients. ( Duran, C; Ercan, I; Ersoy, C; Erturk, E; Guclu, M; Imamoglu, S; Kiyici, S; Selimoglu, H; Tuncel, E, 2009) |
| "Weight gain was less with metformin plus biphasic insulin aspart 70/30 than with repaglinide plus biphasic insulin aspart 70/30 (difference in mean body weight between treatments -2." | 2.74 | Combining insulin with metformin or an insulin secretagogue in non-obese patients with type 2 diabetes: 12 month, randomised, double blind trial. ( Frandsen, M; Hansen, BV; Lund, SS; Nielsen, BB; Parving, HH; Pedersen, O; Tarnow, L; Vaag, AA, 2009) |
| "The combination of repaglinide, metformin and bedtime NPH is safe and effective and it provides better postprandial blood glucose control." | 2.73 | Safety and efficacy of repaglinide in combination with metformin and bedtime NPH insulin as an insulin treatment regimen in type 2 diabetes. ( Civera, M; Martínez, I; Merchante, A; Salvador, M; Sanz, J, 2008) |
| " Collectively, 6-GRF inhibited the adverse effects of CBZ on the antioxidant defence systems, hormonal balance and histology of the testes and epididymis in rats." | 1.46 | 6-Gingerol-rich fraction from Zingiber officinale ameliorates carbendazim-induced endocrine disruption and toxicity in testes and epididymis of rats. ( Adedara, IA; Ajayi, BO; de Souza, D; Farombi, EO; Rocha, JBT; Salihu, M, 2017) |
| " Low doses of carbendazim in combination with low doses of imazalil or cypermethrin caused very pronounced hepatic necrosis, more than any of the three individually applied pesticides or combination of imazalil and cypermethrin." | 1.38 | Carbendazim impends hepatic necrosis when combined with imazalil or cypermethrin. ( Benković, V; Dikić, D; Horvat-Knežević, A; Knežević, F; Landeka, I; Lončar, G; Mojsović-Ćuić, A; Rogić, D; Teparić, R, 2012) |
| "No fenoxycarb was detected (detection limit of 5 ppb) in any neonatal liver, despite the presence of hepatic fenoxycarb residues in the treated ewes, indicating that transplacental transport of fenoxycarb was minimal." | 1.30 | Reproductive effects of fenoxycarb on sheep. ( Abbitt, B; Barr, AC; Fiske, RA; Jaques, JT; Maynard, HR; Reagor, JC, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Fiorentini, F | 1 |
| Germani, M | 1 |
| Del Bene, F | 1 |
| Pellizzoni, C | 1 |
| Cazzaniga, S | 1 |
| Rocchetti, M | 1 |
| Bettica, P | 1 |
| Pucher, J | 1 |
| Gut, T | 1 |
| Mayrhofer, R | 1 |
| El-Matbouli, M | 1 |
| Viet, PH | 1 |
| Ngoc, NT | 1 |
| Lamers, M | 1 |
| Streck, T | 1 |
| Focken, U | 1 |
| Salihu, M | 1 |
| Ajayi, BO | 1 |
| Adedara, IA | 1 |
| de Souza, D | 1 |
| Rocha, JBT | 1 |
| Farombi, EO | 1 |
| Duran, C | 1 |
| Tuncel, E | 1 |
| Ersoy, C | 1 |
| Ercan, I | 1 |
| Selimoglu, H | 1 |
| Kiyici, S | 1 |
| Guclu, M | 1 |
| Erturk, E | 1 |
| Imamoglu, S | 1 |
| Davis, SN | 1 |
| Lund, SS | 1 |
| Tarnow, L | 1 |
| Frandsen, M | 1 |
| Nielsen, BB | 1 |
| Hansen, BV | 1 |
| Pedersen, O | 1 |
| Parving, HH | 1 |
| Vaag, AA | 1 |
| Farag, A | 1 |
| Ebrahim, H | 1 |
| ElMazoudy, R | 1 |
| Kadous, E | 1 |
| Dikić, D | 1 |
| Landeka, I | 1 |
| Knežević, F | 1 |
| Mojsović-Ćuić, A | 1 |
| Benković, V | 1 |
| Horvat-Knežević, A | 1 |
| Lončar, G | 1 |
| Teparić, R | 1 |
| Rogić, D | 1 |
| Cippitelli, A | 1 |
| Astarita, G | 1 |
| Duranti, A | 1 |
| Caprioli, G | 1 |
| Ubaldi, M | 1 |
| Stopponi, S | 1 |
| Kallupi, M | 1 |
| Sagratini, G | 1 |
| Rodrìguez de Fonseca, F | 1 |
| Piomelli, D | 1 |
| Ciccocioppo, R | 1 |
| Furlong, NJ | 1 |
| Hulme, SA | 1 |
| O'Brien, SV | 1 |
| Hardy, KJ | 1 |
| Raskin, P | 2 |
| McGill, J | 1 |
| Saad, MF | 1 |
| Cappleman, JM | 1 |
| Kaye, W | 1 |
| Khutoryansky, N | 1 |
| Hale, PM | 1 |
| Marco, EM | 1 |
| Adriani, W | 1 |
| Canese, R | 1 |
| Podo, F | 1 |
| Viveros, MP | 1 |
| Laviola, G | 1 |
| Davies, MJ | 1 |
| Thaware, PK | 1 |
| Tringham, JR | 1 |
| Howe, J | 1 |
| Jarvis, J | 1 |
| Johnston, V | 1 |
| Kitchener, DL | 1 |
| Skinner, TC | 1 |
| McNally, PG | 1 |
| Lawrence, IG | 1 |
| Civera, M | 1 |
| Merchante, A | 1 |
| Salvador, M | 1 |
| Sanz, J | 1 |
| Martínez, I | 1 |
| Barr, AC | 1 |
| Abbitt, B | 1 |
| Fiske, RA | 1 |
| Jaques, JT | 1 |
| Maynard, HR | 1 |
| Reagor, JC | 1 |
| Connor, RJ | 1 |
| Munyuku, AP | 1 |
| Mackyao, E | 1 |
| Halliwell, RW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Repaglinide Versus Metformin Treatment in Combination With Insulin Biasp30 (Novologmix 70/30) Predinner on Glycemic and Non-Glycemic Cardiovascular Risk-Factors in Non-Obese Patients With Type-2-Diabetes With Unsatisfactory Glycaemic Control Wit[NCT00118963] | Phase 4 | 102 participants (Actual) | Interventional | 2003-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for carbamates and Weight Gain
| Article | Year |
|---|---|
Advances in oral therapy for type 2 diabetes.
Topics: Acarbose; Administration, Oral; Blood Glucose; Carbamates; Cyclohexanes; Diabetes Mellitus, Type 2; | 2000 |
Oral combination therapy: repaglinide plus metformin for treatment of type 2 diabetes.
Topics: Administration, Oral; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Drug Therapy, Combinatio | 2008 |
8 trials available for carbamates and Weight Gain
| Article | Year |
|---|---|
Population pharmacokinetic-pharmacodynamic analysis of givinostat.
Topics: Carbamates; Child; Humans; Male; Models, Biological; Muscular Dystrophy, Duchenne; Weight Gain | 2023 |
Pesticide-contaminated feeds in integrated grass carp aquaculture: toxicology and bioaccumulation.
Topics: Animal Feed; Animals; Carbamates; Carps; Feeding Behavior; Fenitrothion; Fish Diseases; Insecticides | 2014 |
The investigation of the efficacy of insulin glargine on glycemic control when combined with either repaglinide or acarbose in obese Type 2 diabetic patients.
Topics: Acarbose; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; G | 2009 |
Combining insulin with metformin or an insulin secretagogue in non-obese patients with type 2 diabetes: 12 month, randomised, double blind trial.
Topics: Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination | 2009 |
Comparison of repaglinide vs. gliclazide in combination with bedtime NPH insulin in patients with Type 2 diabetes inadequately controlled with oral hypoglycaemic agents.
Topics: Administration, Oral; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Drug Therapy, Combinatio | 2003 |
Combination therapy for type 2 diabetes: repaglinide plus rosiglitazone.
Topics: Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glycated He | 2004 |
A randomized controlled trial examining combinations of repaglinide, metformin and NPH insulin.
Topics: Adult; Aged; Aged, 80 and over; Carbamates; Diabetes Mellitus, Type 2; Drug Administration Schedule; | 2007 |
Safety and efficacy of repaglinide in combination with metformin and bedtime NPH insulin as an insulin treatment regimen in type 2 diabetes.
Topics: Aged; Blood Glucose; Blood Pressure; Body Mass Index; Carbamates; Diabetes Mellitus, Type 2; Drug Ad | 2008 |
8 other studies available for carbamates and Weight Gain
| Article | Year |
|---|---|
6-Gingerol-rich fraction from Zingiber officinale ameliorates carbendazim-induced endocrine disruption and toxicity in testes and epididymis of rats.
Topics: Animals; Benzimidazoles; Carbamates; Catalase; Catechols; Endocrine Disruptors; Epididymis; Fatty Al | 2017 |
Developmental toxicity of fungicide carbendazim in female mice.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Analysis of Variance; Animals; Benzimidazoles; Bl | 2011 |
Carbendazim impends hepatic necrosis when combined with imazalil or cypermethrin.
Topics: Animals; Benzimidazoles; Biomarkers; Carbamates; Chemical and Drug Induced Liver Injury; Drug Intera | 2012 |
Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition.
Topics: Acute Disease; Amidohydrolases; Animals; Anxiety; Arachidonic Acids; Benzamides; Brain; Cannabinoid | 2011 |
Insulin in type 2 diabetes: a useful alternative despite limited assessment based on surrogate endpoints.
Topics: Acarbose; Administration, Oral; Carbamates; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Gl | 2005 |
Enhancement of endocannabinoid signalling during adolescence: Modulation of impulsivity and long-term consequences on metabolic brain parameters in early maternally deprived rats.
Topics: Amidohydrolases; Animals; Benzamides; Brain; Brain Chemistry; Cannabinoid Receptor Modulators; Carba | 2007 |
Reproductive effects of fenoxycarb on sheep.
Topics: Animals; Blood Chemical Analysis; Body Weight; Carbamates; Dose-Response Relationship, Drug; Estrus; | 1997 |
Helminthosis in goats in southern Tanzania: investigations on epidemiology and control.
Topics: Animals; Carbamates; Feces; Female; Goat Diseases; Goats; Helminthiasis; Helminthiasis, Animal; Inte | 1990 |