carbamates has been researched along with Uremia in 18 studies
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Scatchard plots for sulfadiazine binding in plasma from patients with uremia and in normal plasma carbamylated in vitro with potassium cyanate showed changes in the 2 groups when compared with those in normal individuals." | 3.66 | Plasma protein carbamylation and decreased acidic drug protein binding in uremia. ( Calvo, R; Carlos, R; Erill, S, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (33.33) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, ML | 1 |
| Huang, CF | 1 |
| Wei, YJ | 1 |
| Lin, WY | 1 |
| Lin, YH | 1 |
| Hsu, PY | 1 |
| Hsu, CT | 1 |
| Liu, TW | 1 |
| Lee, JJ | 1 |
| Niu, SW | 1 |
| Huang, JC | 1 |
| Hung, TS | 1 |
| Yeh, ML | 1 |
| Huang, CI | 1 |
| Liang, PC | 1 |
| Hsieh, MY | 1 |
| Chen, SC | 1 |
| Huang, JF | 1 |
| Chang, JM | 1 |
| Chiu, YW | 1 |
| Dai, CY | 1 |
| Hwang, SJ | 1 |
| Chuang, WL | 1 |
| Pietrement, C | 1 |
| Gorisse, L | 1 |
| Jaisson, S | 1 |
| Gillery, P | 1 |
| Kalim, S | 1 |
| Karumanchi, SA | 1 |
| Thadhani, RI | 1 |
| Berg, AH | 1 |
| Schreier, SM | 1 |
| Hollaus, M | 1 |
| Hermann, M | 1 |
| Jirovetz, L | 1 |
| Exner, M | 1 |
| Kapiotis, S | 1 |
| Gmeiner, BM | 1 |
| Laggner, H | 1 |
| Wang, Z | 1 |
| Nicholls, SJ | 1 |
| Rodriguez, ER | 1 |
| Kummu, O | 1 |
| Hörkkö, S | 1 |
| Barnard, J | 1 |
| Reynolds, WF | 1 |
| Topol, EJ | 1 |
| DiDonato, JA | 1 |
| Hazen, SL | 1 |
| Tesio, F | 1 |
| Cecchin, E | 1 |
| De Marchi, S | 1 |
| Quaia, P | 1 |
| Clegg, LS | 1 |
| Lindup, WE | 1 |
| Flückiger, R | 1 |
| Harmon, W | 1 |
| Meier, W | 1 |
| Loo, S | 1 |
| Gabbay, KH | 1 |
| Harding, JJ | 1 |
| Rixon, KC | 1 |
| Erill, S | 2 |
| Calvo, R | 1 |
| Carlos, R | 1 |
| Frazao, JM | 1 |
| Barth, RH | 1 |
| Berlyne, GM | 2 |
| Davenport, A | 1 |
| Jones, S | 1 |
| Goel, S | 1 |
| Astley, JP | 1 |
| Feest, TG | 1 |
| Kraus, LM | 1 |
| Kraus, AP | 1 |
| Hasuike, Y | 1 |
| Nakanishi, T | 1 |
| Maeda, K | 1 |
| Tanaka, T | 1 |
| Inoue, T | 1 |
| Takamitsu, Y | 1 |
| Dengler, TJ | 1 |
| Robertz-Vaupel, GM | 1 |
| Dengler, HJ | 1 |
| Bezek, S | 1 |
| Scasnár, V | 1 |
| Kukan, M | 1 |
| Trnovec, T | 1 |
| du Souich, P | 1 |
| Courteau, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Micro-elimination of Hepatitis C Virus Infection With Pan-genotypic DAA Regimen in Hepatitis C Highly Endemic and Contagious Community (ERASE-C)[NCT03891550] | Phase 3 | 135 participants (Anticipated) | Interventional | 2019-05-13 | Active, not recruiting | ||
| Comprehensive Surveillance of HCV Infecion in Uremics Under Maintenance Hemodialysis and Linking to Medical Care in Taiwan[NCT03803410] | 2,973 participants (Actual) | Observational | 2019-01-07 | Completed | |||
| Clinical Follow-up of Anti-Carbamylated Antibody Status in Rheumatoid Arthritis Patients at 6, 12 and 18 Months[NCT02958319] | 278 participants (Actual) | Observational | 2016-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"To explore the clinical differences in activity indexes (DAS28-ESR) at 6, 12 and 18 months of follow-up according the anti-CarP status.~The DAS28 is a composite score derived from 4 measures, one of them can be the erythrocyte sedimentation rate (ESR). We will be using the DAS28-ESR version. To calculate the DAS28-ESR the rheumatologist or specialist nurse will:- count the number of swollen joints (out of the 28), count the number of tender joints (out of the 28), take blood to measure ESR, ask participants to make a 'global assessment of health' (indicated by marking a 10 cm line between very good and very bad).~DAS28-ESR is calculated with classic calculators and resulting values are interpreted as follows:~<2.6: disease remission 2.6 - 3.2: low disease activity 3.2 - 5.1: moderate disease activity >5.1: high disease activity" (NCT02958319)
Timeframe: 6, 12 and 18 Months
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| 6 MONTHS | 12 MONTHS | 18 MONTHS | |
| Anti P Carb Negative RA Patients | 3.75 | 3.59 | 3.65 |
| Anti P Carb Positive RA Patients | 3.72 | 3.69 | 3.77 |
3 reviews available for carbamates and Uremia
| Article | Year |
|---|---|
Protein carbamylation in kidney disease: pathogenesis and clinical implications.
Topics: Animals; Biomarkers; Carbamates; Humans; Kidney Failure, Chronic; Male; Middle Aged; Protein Process | 2014 |
Carbamylated proteins and peptides in health and in uremia.
Topics: Carbamates; Hemoglobin A; Humans; Lipid Metabolism; Peptides; Renal Dialysis; Uremia | 1998 |
Carbamoylation of amino acids and proteins in uremia.
Topics: Amino Acids; Animals; Carbamates; Cyanates; Diabetic Nephropathies; Enzymes; Glucose; Hormones; Huma | 2001 |
1 trial available for carbamates and Uremia
| Article | Year |
|---|---|
Carbamylated hemoglobin: a potential marker for the adequacy of hemodialysis therapy in end-stage renal failure.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Carbamates; Diabetes Mellitus; | 1996 |
14 other studies available for carbamates and Uremia
| Article | Year |
|---|---|
Establishment of an outreach, grouping healthcare system to achieve microelimination of HCV for uremic patients in haemodialysis centres (ERASE-C).
Topics: Antiviral Agents; Carbamates; Drug Combinations; Hemodialysis Units, Hospital; Hepatitis C; Heterocy | 2021 |
Establishment of an outreach, grouping healthcare system to achieve microelimination of HCV for uremic patients in haemodialysis centres (ERASE-C).
Topics: Antiviral Agents; Carbamates; Drug Combinations; Hemodialysis Units, Hospital; Hepatitis C; Heterocy | 2021 |
Establishment of an outreach, grouping healthcare system to achieve microelimination of HCV for uremic patients in haemodialysis centres (ERASE-C).
Topics: Antiviral Agents; Carbamates; Drug Combinations; Hemodialysis Units, Hospital; Hepatitis C; Heterocy | 2021 |
Establishment of an outreach, grouping healthcare system to achieve microelimination of HCV for uremic patients in haemodialysis centres (ERASE-C).
Topics: Antiviral Agents; Carbamates; Drug Combinations; Hemodialysis Units, Hospital; Hepatitis C; Heterocy | 2021 |
Chronic increase of urea leads to carbamylated proteins accumulation in tissues in a mouse model of CKD.
Topics: Animals; Carbamates; Collagen; Disease Models, Animal; Extracellular Matrix; Female; Kinetics; Mice; | 2013 |
Carbamoylated free amino acids in uremia: HOCl generates volatile protein modifying and cytotoxic oxidant species from N-carbamoyl-threonine but not threonine.
Topics: Aldehydes; Carbamates; Cell Line; Cytotoxins; Humans; Hypochlorous Acid; Lipoproteins, LDL; Oxidants | 2012 |
Protein carbamylation links inflammation, smoking, uremia and atherogenesis.
Topics: Animals; Atherosclerosis; Blood Proteins; Carbamates; Cholesterol; Citrulline; Clinical Trials as To | 2007 |
Glycosylated or carbamylated hemoglobin in uremia?
Topics: Carbamates; Glucose Tolerance Test; Glycated Hemoglobin; Hemoglobin A; Humans; Renal Dialysis; Uremi | 1982 |
Drug binding defect of uraemic plasma: unlikely involvement of carbamoylated albumin.
Topics: Animals; Azo Compounds; Carbamates; Cattle; Humans; Pharmaceutical Preparations; Protein Binding; Sa | 1982 |
Hemoglobin carbamylation in uremia.
Topics: Adolescent; Adult; Aged; Carbamates; Child; Child, Preschool; Chromatography, Gas; Cyanates; Hemoglo | 1981 |
Is diarrhoea a major cause of cataract in some tropical countries?
Topics: Acidosis; Animals; Carbamates; Cataract; Cattle; Dehydration; Diarrhea; Eye Proteins; Humans; In Vit | 1981 |
Plasma protein carbamylation and decreased acidic drug protein binding in uremia.
Topics: Adult; Binding Sites; Binding, Competitive; Blood Proteins; Carbamates; Charcoal; Cyanates; Female; | 1980 |
Carbamylated hemoglobin in prerenal azotemia.
Topics: Aged; Aged, 80 and over; Blood Urea Nitrogen; Carbamates; Creatinine; Diagnosis, Differential; Femal | 1995 |
Carbamylated hemoglobin as a therapeutic marker in hemodialysis.
Topics: Biomarkers; Blood Urea Nitrogen; Carbamates; Female; Hemoglobins; Humans; Kidney Failure, Chronic; M | 2002 |
Albumin binding in uraemia: quantitative assessment of inhibition by endogenous ligands and carbamylation of albumin.
Topics: Amino Acid Sequence; Binding, Competitive; Carbamates; Dansyl Compounds; Fluorescent Dyes; Glycine; | 1992 |
Kinetics of biliary elimination of pentacaine in rats.
Topics: Animals; Bile; Bile Ducts; Brain; Carbamates; Feces; Injections, Intravenous; Liver; Male; Rats; Rat | 1990 |
Carbamylation of proteins and sulfacetamide free fraction in serum in experimentally-induced high blood urea states.
Topics: Animals; Blood Proteins; Blood Urea Nitrogen; Carbamates; Creatinine; Kidney Failure, Chronic; Male; | 1985 |